Bmc Bioinformatics, Zhenqiang Su, Huixiao Hong, Hong Fang, Leming Shi, Roger Perkins, ...
Proceedings Very Important Pool (VIP) genes – an application for microarray-based molecular signatures
Bmc Bioinformatics, Hapmap Samples, Huixiao Hong, Zhenqiang Su, Weigong Ge, Leming Shi, ...
Proceedings Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270
ebTrack: an environmental bioinformatics system built upon ArrayTrack™ (2009)
Chen, Minjun, Martin, Jackson, Fang, Hong, Isukapalli, Sastry, Georgopoulos, Panos G, Welsh, William J, ...
Abstract ebTrack is being developed as an integrated bioinformatics system for environmental research and analysis by addressing the issues of integration, curation, management, first level analysis...
Fan, Xiaohui, Shi, Leming, Fang, Hong, Harris, Stephen, Perkins, Roger, Tong, Weida
Abstract Recent publications have raised concerns about the reliability of microarray technology because of the lack of reproducibility of differentially expressed genes (DEGs) from highly similar...
Toxicogenomics and Cell-based Assays for Toxicology (2009)
Weida Tong, Hong Fang, Donna Mendrick
Toxicity is usually investigated using a set of standardized animal-based studies which, unfortunately, fail to detect all compounds that induce human adverse events and do not provide detailed...
Weida Tong, Qian Xie, Huixiao Hong, Hong Fang, Leming Shi, Roger Perkins, ...
Class prediction using “omics ” data is playing an increasing role in toxicogenomics, diagnosis/prognosis, and risk assessment. These data are usually noisy and represented by relatively few...
Very Important Pool (VIP) genes – an application for microarray-based molecular signatures (2008)
Su, Zhenqiang, Hong, Huixiao, Fang, Hong, Shi, Leming, Perkins, Roger, Tong, Weida
Abstract Background Advances in DNA microarray technology portend that molecular signatures from which microarray will eventually be used in clinical environments and personalized medicine....
Hong, Huixiao, Su, Zhenqiang, Ge, Weigong, Shi, Leming, Perkins, Roger, Fang, Hong, ...
Abstract Background Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associated with...
Shi, Leming, Jones, Wendell D, Jensen, Roderick V, Harris, Stephen C, Perkins, Roger G, Goodsaid, Federico M, ...
Abstract Background Reproducibility is a fundamental requirement in scientific experiments. Some recent publications have claimed that microarrays are unreliable because lists of differentially...
The Reproducibility of Lists of Differentially Expressed Genes in Microarray Studies (2007)
Leming D. Shi, Wendell D. Jones, Roderick V. Jensen, Stephen C. Harris, Roger G. Perkins, Federico M. Goodsaid, ...
Reproducibility is a fundamental requirement in scientific experiments and clinical contexts. Recent publications raise concerns about the reliability of microarray technology because of the apparent...
The Reproducibility of Lists of Differentially Expressed Genes in Microarray Studies (2007)
Leming Shi, Wendell D. Jones, Roderick V. Jensen, Stephen C. Harris, Roger G. Perkins, Federico M. Goodsaid, ...
Reproducibility is a fundamental requirement in scientific experiments and clinical contexts. Recent publications raise concerns about the reliability of microarray technology because of the apparent...
Guo, Lei, Fang, Hong, Collins, Jim, Fan, Xiao-hui, Dial, Stacey, Wong, Alex, ...
Abstract Background Fibrates are a unique hypolipidemic drugs that lower plasma triglyceride and cholesterol levels through their action as peroxisome proliferator-activated receptor alpha (PPARα)...
Chen, Tao, Guo, Lei, Zhang, Lu, Shi, Leming, Fang, Hong, Sun, Yongming, ...
Abstract Background Aristolochic acid (AA) is the active component of herbal drugs derived from Aristolochia species that have been used for medicinal purposes since antiquity. AA, however, induced...
Sun, Hongmei, Fang, Hong, Chen, Tao, Perkins, Roger, Tong, Weida
Abstract Background Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular components,...
Bmc Bioinformatics, Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, Weida Tong, ...
© 2006 Sun et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License
Bmc Bioinformatics, Lei Guo, Hong Fang, Jim Collins, Xiao-hui Fan, Stacey Dial, ...
Proceedings Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor α agonists
Microarray scanner calibration curves: characteristics and implications (2005)
Shi, Leming, Tong, Weida, Su, Zhenqiang, Han, Tao, Han, Jing, Puri, Raj K, ...
Abstract Background Microarray-based measurement of mRNA abundance assumes a linear relationship between the fluorescence intensity and the dye concentration. In reality, however, the calibration...
Shi, Leming, Tong, Weida, Fang, Hong, Scherf, Uwe, Han, Jing, Puri, Raj K, ...
Abstract Background The acceptance of microarray technology in regulatory decision-making is being challenged by the existence of various platforms and data analysis methods. A recent report (E....
Hong, Huixiao, Dragan, Yvonne, Epstein, Joshua, Teitel, Candee, Chen, Bangzheng, Xie, Qian, ...
Abstract Background Proteomic profiling of complex biological mixtures by the ProteinChip technology of surface-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectrometry (MS)...
Weida Tong, Xiaoxi Cao, Stephen Harris, Hongmei Sun, Hong Fang, James Fuscoe, ...
The mapping of the human genome and the determination of corresponding gene functions, pathways, and biological mechanisms are driving the emergence of the new research fields of toxicogenomics and...
TITLE: Embedded Memory BIST for Systems-on-a-Chip (2003)
Bai Hong Fang, B. Eng (electrical, Hong Fang, B. Eng (electrical, Supervisor Dr. Nicola Nicolici
ii Embedded memories consume an increasing portion of the die area in deep submicron systems-on-a-chip (SOCs). Manufacturing test of embedded memories is an essential step in the SOC production that...
Blair, Robert M., Fang, Hong, Branham, William S., Hass, Bruce S., Dial, Stacey L., Moland, Carrie L., ...
We have utilized a validated (standardized) estrogen receptor (ER) competitive-binding assay to determine the ER affinity for a large, structurally diverse group of chemicals. Uteri from...
Government of the United States; the Large Scale Networking Working (1998)
Leming M. Shi, Hong Fang, Weida Tong, Jie Wu, Roger Perkins, Robert M. Blair, ...
Endocrine disruptors (EDs) have a variety of adverse effects in humans and animals. About 58 000 chemicals, most having little safety data, must be tested in a group of tiered assays. As assays will...
Includes abstract.
Thesis research directed by Dept. of Mechanical Engineering.
Thesis (M.S.)--University of Nebraska--Lincoln, 1992.
A screening method for methicillin-resistant Staphylococcus aureus (MRSA) by using selective broth and real-time PCR (broth-PCR) was developed and evaluated. The samples (n = 304) were cultured in...
Fang, Hong, Lundberg, Christina, Olsson-Liljequist, Barbro, Hedin, Göran, Lindbäck, Emma, Rosenberg, Åsa, ...
From June to October of 2002, a cluster of Escherichia coli isolates producing extended-spectrum β-lactamases (ESBLs) was detected in Stockholm. The isolates were grouped into two clones, one of...
Inducible Metronidazole Resistance and nim Genes in Clinical Bacteroides fragilis Group Isolates
Löfmark, Sonja, Fang, Hong, Hedberg, Maria, Edlund, Charlotta
Nitroimidazole resistance (nim) genes were detected in 2% of 1,502 clinical Bacteroides fragilis group strains isolated from 19 European countries, and a novel nim gene was identified. High...
Thirty-nine methicillin-resistant Staphylococcus aureus (MRSA) isolates with diverse genetic backgrounds and two reference strains were correctly identified as S. aureus on CHROMagar MRSA and S....
Hong, Huixiao, Tong, Weida, Fang, Hong, Shi, Leming, Xie, Qian, Wu, Jie, ...
A number of environmental chemicals, by mimicking natural hormones, can disrupt endocrine function in experimental animals, wildlife, and humans. These chemicals, called "endocrine-disrupting...
Tong, Weida, Cao, Xiaoxi, Harris, Stephen, Sun, Hongmei, Fang, Hong, Fuscoe, James, ...
The mapping of the human genome and the determination of corresponding gene functions, pathways, and biological mechanisms are driving the emergence of the new research fields of toxicogenomics and...
Tong, Weida, Xie, Qian, Hong, Huixiao, Fang, Hong, Shi, Leming, Perkins, Roger, ...
Class prediction using “omics” data is playing an increasing role in toxicogenomics, diagnosis/prognosis, and risk assessment. These data are usually noisy and represented by relatively few...
Tong, Weida, Xie, Qian, Hong, Huixiao, Shi, Leming, Fang, Hong, Perkins, Roger
Quantitative structure–activity relationship (QSAR) methods have been widely applied in drug discovery, lead optimization, toxicity prediction, and regulatory decisions. Despite major advances in...
A cefoxitin-based selective broth was evaluated for its efficiency in detecting methicillin-resistant Staphylococcus aureus (MRSA) by the use of laboratory reference strains, clinical isolates of...
A yeast assay probes the interaction between botulinum neurotoxin serotype B and its SNARE substrate
Fang, Hong, Luo, Wentian, Henkel, Jim, Barbieri, Joseph, Green, Neil
The seven functionally distinct serotypes (A–G) of botulinum neurotoxin (BoNT) are dichains consisting of light chain (LC) with zinc-dependent endoprotease activity connected by one disulfide bond...
Microarray scanner calibration curves: characteristics and implications
Shi, Leming, Tong, Weida, Su, Zhenqiang, Han, Tao, Han, Jing, Puri, Raj K, ...
Chen, Tao, Guo, Lei, Zhang, Lu, Shi, Leming, Fang, Hong, Sun, Yongming, ...
A screening method for methicillin-resistant Staphylococcus aureus (MRSA) by using selective broth and real-time PCR (broth-PCR) was developed and evaluated. The samples (n = 304) were cultured in...
Fang, Hong, Lundberg, Christina, Olsson-Liljequist, Barbro, Hedin, Göran, Lindbäck, Emma, Rosenberg, Åsa, ...
From June to October of 2002, a cluster of Escherichia coli isolates producing extended-spectrum β-lactamases (ESBLs) was detected in Stockholm. The isolates were grouped into two clones, one of...
Inducible Metronidazole Resistance and nim Genes in Clinical Bacteroides fragilis Group Isolates
Löfmark, Sonja, Fang, Hong, Hedberg, Maria, Edlund, Charlotta
Nitroimidazole resistance (nim) genes were detected in 2% of 1,502 clinical Bacteroides fragilis group strains isolated from 19 European countries, and a novel nim gene was identified. High...
Thirty-nine methicillin-resistant Staphylococcus aureus (MRSA) isolates with diverse genetic backgrounds and two reference strains were correctly identified as S. aureus on CHROMagar MRSA and S....
Hong, Huixiao, Tong, Weida, Fang, Hong, Shi, Leming, Xie, Qian, Wu, Jie, ...
A number of environmental chemicals, by mimicking natural hormones, can disrupt endocrine function in experimental animals, wildlife, and humans. These chemicals, called "endocrine-disrupting...
Tong, Weida, Cao, Xiaoxi, Harris, Stephen, Sun, Hongmei, Fang, Hong, Fuscoe, James, ...
The mapping of the human genome and the determination of corresponding gene functions, pathways, and biological mechanisms are driving the emergence of the new research fields of toxicogenomics and...
Tong, Weida, Xie, Qian, Hong, Huixiao, Fang, Hong, Shi, Leming, Perkins, Roger, ...
Class prediction using “omics” data is playing an increasing role in toxicogenomics, diagnosis/prognosis, and risk assessment. These data are usually noisy and represented by relatively few...
Tong, Weida, Xie, Qian, Hong, Huixiao, Shi, Leming, Fang, Hong, Perkins, Roger
Quantitative structure–activity relationship (QSAR) methods have been widely applied in drug discovery, lead optimization, toxicity prediction, and regulatory decisions. Despite major advances in...
A cefoxitin-based selective broth was evaluated for its efficiency in detecting methicillin-resistant Staphylococcus aureus (MRSA) by the use of laboratory reference strains, clinical isolates of...
A yeast assay probes the interaction between botulinum neurotoxin serotype B and its SNARE substrate
Fang, Hong, Luo, Wentian, Henkel, Jim, Barbieri, Joseph, Green, Neil
The seven functionally distinct serotypes (A–G) of botulinum neurotoxin (BoNT) are dichains consisting of light chain (LC) with zinc-dependent endoprotease activity connected by one disulfide bond...
Microarray scanner calibration curves: characteristics and implications
Shi, Leming, Tong, Weida, Su, Zhenqiang, Han, Tao, Han, Jing, Puri, Raj K, ...
Chen, Tao, Guo, Lei, Zhang, Lu, Shi, Leming, Fang, Hong, Sun, Yongming, ...
Fang, Hong, Ataker, Ferda, Hedin, Göran, Dornbusch, Kathrine
The genetic characteristics and molecular epidemiology of extended-spectrum β-lactamases (ESBLs) among Escherichia coli isolates were investigated at a general hospital and its associated health...
Very Important Pool (VIP) genes – an application for microarray-based molecular signatures
Su, Zhenqiang, Hong, Huixiao, Fang, Hong, Shi, Leming, Perkins, Roger, Tong, Weida
Shi, Leming, Jones, Wendell D, Jensen, Roderick V, Harris, Stephen C, Perkins, Roger G, Goodsaid, Federico M, ...
Survey on skin aging status and related influential factors in Southeast China*
Wang, Yi-na, Fang, Hong, Zhu, Wei-fang
Objective: To investigate cutaneous aging patterns of residents in Hangzhou, Zhejiang, China, and their contributing factors. Methods: Eight hundred and forty-eight Hangzhou residents received the...
Fan, Xiaohui, Shi, Leming, Fang, Hong, Harris, Stephen, Perkins, Roger, Tong, Weida
Recent publications have raised concerns about the reliability of microarray technology because of the lack of reproducibility of differentially expressed genes (DEGs) from highly similar studies...
ebTrack: an environmental bioinformatics system built upon ArrayTrack™
Chen, Minjun, Martin, Jackson, Fang, Hong, Isukapalli, Sastry, Georgopoulos, Panos G, Welsh, William J, ...
ebTrack is being developed as an integrated bioinformatics system for environmental research and analysis by addressing the issues of integration, curation, management, first level analysis and...