Hong Sun

Publication List Details

Period

1985 - 2009

Number

104

Co-Authors

A sewing needle in liver: a case report and review of the literature (2009)

Feng, Quan Zhou, Wang, Jie, Sun, Hong

Abstract Introduction Hepatic foreign bodies are quite rare. A sewing needle as a hepatic foreign body in an old woman is very rare and the managements have been varied. Case presentation An old...

Different Representations for Recursive Systematic Convolutional Codes and Their Associated Decoding for Turbo Codes (2009)

Hong Sun, Zhong-jie Li, Didier Le Ruyet

Abstract – The representations of recursive systematic convolutional (RSC) codes based on parity-check equations can be flexibly transformed into different forms with or without auxiliary variable....

pour les turbo (2009)

Didier Le Ruyet, Hong Sun, Han Vu Thien

Nouvelle methode de construction d'entrelaceurs

Genomic regions with distinct genomic distance conservation in vertebrate genomes (2009)

Sun, Hong, Skogerbø, Geir, Zheng, Xiaohui, Liu, Wei, Li, Yixue

Abstract Background A number of vertebrate highly conserved elements (HCEs) have been detected and their genomic interval distances have been reported to be more conserved than protein coding genes...

ModuleDigger: an itemset mining framework for the detection of cis-regulatory modules (2009)

Sun, Hong, De Bie, Tijl, Storms, Valerie, Fu, Qiang, Dhollander, Thomas, Lemmens, Karen, ...

Abstract Background The detection of cis -regulatory modules (CRMs) that mediate transcriptional responses in eukaryotes remains a key challenge in the postgenomic era. A CRM is characterized by a...

ModuleDigger: an itemset mining framework for the detection of cis-regulatory modules (2009)

Sun, Hong, De Bie, Tijl, Storms, Valerie, Fu, Qiang, Dhollander, Thomas, Lemmens, Karen, ...

Background The detection of cis-regulatory modules (CRMs) that mediate transcriptional responses in eukaryotes remains a key challenge in the postgenomic era. A CRM is characterized by a set of...

Turbo-like Iterative Thresholding for SAR Image Recovery from Compressed Measurements (2009)

Yu, Lei, Yang, Yi, Sun, Hong

Compressive sensing (CS) has attracted many re- searchers since it offers a novel paradigm that one can acquire signals at a sub-Nyquist rate, and provides an implicit application of imaging and...

Turbo-like Iterative Thresholding for SAR Image Recovery from Compressed Measurements (2009)

Yu, Lei, Yang, Yi, Sun, Hong

Compressive sensing (CS) has attracted many re- searchers since it offers a novel paradigm that one can acquire signals at a sub-Nyquist rate, and provides an implicit application of imaging and...

SPEECH ENHANCEMENT BASED ON TURBO ITERATION (2009)

Dong, Hang, Sun, Hong

A Turbo iterative method for speech enhancement is proposed. The Kalman filter with the voice generation model and the wavelet threshold filter with the short-term spectrum are combined through Turbo...

SPEECH ENHANCEMENT BASED ON TURBO ITERATION (2009)

Dong, Hang, Sun, Hong

A Turbo iterative method for speech enhancement is proposed. The Kalman filter with the voice generation model and the wavelet threshold filter with the short-term spectrum are combined through Turbo...

Sulindac Sulfide Differentially Induces Apoptosis in Smac-Proficient and -Deficient Human Colon Cancer Cells (2009)

Jingxue Shi, Qin He, Jie An, Hong Sun, Ying Huang, M. Saeed Sheikh

Sulindac, the non-steroidal anti-inflammatory drug has shown promise in the prevention of colon cancer but the molecular mechanisms by which it mediates such effects remain to be elucidated. Sulindac...

Nitric oxide synthase-dependent responses of the basilar artery during acute infusion of nicotine (2009)

Mayhan, William G., Arrick, Denise M., Sharpe, Glenda M., Sun, Hong

Introduction: Our goals were to determine whether acute exposure to nicotine alters nitric oxide synthase (NOS)–dependent responses of the basilar artery and to identify a potential role for...

The association of interleukin-16 polymorphisms with IL-16 serum levels and risk of colorectal and gastric cancer (2009)

Gao, Lin-Bo, Rao, Li, Wang, Yan-Yun, Liang, Wei-Bo, Li, Cui, Xue, Hui, ...

Interleukin (IL)-16, a multifunctional cytokine, plays a fundamental role in inflammatory diseases, as well as in the development and progression of tumors. Genetic variation in the DNA sequence of...

CoMRI: A Compressed Multi-Resolution Index Structure for Sequence Similarity Queries (2008)

Hong Sun, Ozgur Ozturk

We present CoMRI, Compressed M ulti-Resolution I ndex, our system for fast sequence similarity search in DNA sequence databases. Since the size of such sequence databases is usually large and varying...

An enhanced partial order curve comparison algorithm and its application to analyzing protein folding trajectories (2008)

Sun, Hong, Ferhatosmanoglu, Hakan, Ota, Motonori, Wang, Yusu

Abstract Background Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produce a huge...

CoMRI: A Compressed Multi-Resolution Index Structure for Sequence Similarity Queries (2008)

Hong Sun, Ozgur Ozturk

In this paper, we present CoMRI, Compressed Multi-Resolution Index, our system for fast sequence similarity search in DNA sequence databases. We employ Virtual Bounding Rectangle (VBR) concept to...

Properties of Finite Response Input Sequences of Recursive Convolutional Codes (2008)

Didier Le Ruyet, Hong Sun, Han Vu Thien

Abstract. A recursive convolutional encoder can be regarded as an innite impulse response system over the Galois Field of order 2. First, in this paper, we introduce nite response input sequences for...

ENHANCED PARTIAL ORDER CURVE COMPARISON OVER MULTIPLE PROTEIN FOLDING TRAJECTORIES (2008)

Hong Sun, Hakan Ferhatosmanoglu, Motonori Ota, Yusu Wang

Understanding how proteins fold is essential to our quest in discovering how life works at the molecular level. Current computation power enables researchers to produce a huge amount of folding...

A simple and accurate SNP scoring strategy based on typeIIS restriction endonuclease cleavage and matrix-assisted laser desorption/ionization mass spectrometry (2008)

Hong Sun, Ji Seung, Rhee Hwanseok, Shin Soo, Hwang Sun, Lee Seung, ...

Abstract Background We describe the development of a novel matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF)-based single nucleotide polymorphism (SNP) scoring strategy, termed...

Rigorous Development of Fault-Tolerant Transactions for Information Retrieval Systems Using Event-B (2008)

Hong-Jiang Gao, Hong Sun, Bang-Hai Xu, Ying He, Zheng Qin

The aim of this study is to demonstrate the approach of stepwise development of a distributed transaction mechanism for information retrieval systems. In this study, we formally develop an abstract...

Nickel compounds induce phosphorylation of histone H3 at serine 10 by activating JNK-MAPK pathway (2008)

Ke, Qingdong, Li, Qin, Ellen, Thomas P., Sun, Hong, Costa, Max

Nickel (Ni) is a known carcinogen, although the mechanism of its carcinogenicity is not clear. Here, we provide evidence that Ni can induce phosphorylation of histone H3 at its serine 10 residue in a...

Arsenite alters global histone H3 methylation (2008)

Zhou, Xue, Sun, Hong, Ellen, Thomas P., Chen, Haobin, Costa, Max

Arsenic (As) is a well-characterized human carcinogen but is generally not mutagenic. The evidence that As induces both loss of global DNA methylation and gene promoter DNA hypermethylation has...

CoMRI: A Compressed Multi-Resolution Index Structure for Sequence (2007)

Similarity Queries Hong, Hong Sun, Ozgur Ozturk, Hakan Ferhatosmano Glu

In this paper, we present CoMRI, Compressed MultiResolution Index, our system for fast sequence similarity search in DNA sequence databases. We employ Virtual Bounding Rectangle (VBR) concept to...

bZIPDB : A database of regulatory information for human bZIP transcription factors (2007)

Ryu Taewoo, Jung Juhyun, Lee Sunjae, Nam Ho, Hong Sun, Yoo Jae, ...

Abstract Background Basic region-leucine zipper (bZIP) proteins are a class of transcription factors (TFs) that play diverse roles in eukaryotes. Malfunctions in these proteins lead to cancer and...

bHLH-Orange Transcription Factors in Development and Cancer (2007)

Hong Sun, Saghi Ghaffari, Reshma Taneja

Basic helix-loop-helix (bHLH) proteins are a large superfamily of transcription factors that play critical roles in many physiological processes including cellular differentiation, cell cycle arrest...

Conserved distances between vertebrate highly conserved elements (2006)

Sun, Hong, Skogerbø, Geir, Chen, Runsheng

High numbers of sequence element with very high (>95%) sequence conservation between the human and other vertebrate genomes have been reported and ascribed putative cis-regulatory functions. We have...

Conserved distances between vertebrate highly conserved elements (2006)

Sun, Hong, Skogerbø, Geir, Chen, Runsheng

High numbers of sequence element with very high (>95 %) sequence conservation between the human and other vertebrate genomes have been reported and ascribed putative cis-regulatory functions. We have...

Organization of the Caenorhabditis elegans small non-coding transcriptome: Genomic features, biogenesis, and expression (2006)

Deng, Wei, Zhu, Xiaopeng, Skogerbø, Geir, Zhao, Yi, Fu, Zhuo, Wang, Yudong, ...

Recent evidence points to considerable transcription occurring in non-protein-coding regions of eukaryote genomes. However, their lack of conservation and demonstrated function have created...

Organization of the Caenorhabditis elegans small non-coding transcriptome: Genomic features, biogenesis, and expression (2005)

Deng, Wei, Zhu, Xiaopeng, Skogerbø, Geir, Zhao, Yi, Fu, Zhuo, Wang, Yudong, ...

Recent evidence points to considerable transcription occurring in non-protein-coding regions of eukaryote genomes. However, their lack of conservation and demonstrated function have created...

Reply to "Comment on `First-principles calculation of the superconducting transition in MgB2 within the anisotropic Eliashberg formalism'" (2003)

Choi, Hyoung Joon, Roundy, David, Sun, Hong, Cohen, Marvin L., Louie, Steven G.

The recent preprint by Mazin et al. [cond-mat/0212417] contains many inappropriate evaluations and/or criticisms on our published work [Phys. Rev. B 66, 020513 (2002) and Nature 418, 758 (2002)]. The...

Hydrodynamics and mass transfer in Venturi scrubbers / (2003)

Sun, Hong.

Thesis (Ph.D.)--University of Nottingham, 2004.

Dorsal horn-enriched genes identified by DNA microarray, in situ hybridization and immunohistochemistry (2002)

Sun, Hong, Xu, Jian, Della Penna, Kimberly B, Benz, Robert J, Kinose, Fumi, Holder, Daniel J, ...

Abstract Background Neurons in the dorsal spinal cord play important roles in nociception and pain. These neurons receive input from peripheral sensory neurons and then transmit the signals to the...

Local-field distribution in resonant composites: Green's-function formalism (2001)

Gu, Ying, Yu, K. W., Sun, Hong

The effective response depends sensitively on composite microstructure due to large fluctuations in the local electric field. For metallic clusters embedded in a dielectric host, the local field...

First-Principles Calculation of the Superconducting Transition in MgB2 within the Anisotropic Eliashberg Formalism (2001)

Choi, Hyoung Joon, Roundy, David, Sun, Hong, Cohen, Marvin L., Louie, Steven G.

We present a study of the superconducting transition in MgB2 using the ab-initio pseudopotential density functional method and the fully anisotropic Eliashberg equation. Our study shows that the...

Superconducting energy gaps, low temperature specific heat, and quasiparticle spectra of MgB2 (2001)

Choi, Hyoung Joon, Roundy, David, Sun, Hong, Cohen, Marvin L., Louie, Steven G.

We report first-principles calculations of the k- and T-dependent superconducting gap Delta(k,T) in MgB2 and its manifestation in various measured quantities. Because the Fermi surface has...

Spectral Representation Theory for Dielectric Behavior of Nonspherical Cell Suspensions (2001)

Huang, J. P., Yu, K. W., Lei, Jun, Sun, Hong

Recent experiments revealed that the dielectric dispersion spectrum of fission yeast cells in a suspension was mainly composed of two sub-dispersions. The low-frequency sub-dispersion depended on the...

Dielectric Behavior of Nonspherical Cell Suspensions (2001)

Lei, Jun, Wan, Jones T. K., Yu, K. W., Sun, Hong

Recent experiments revealed that the dielectric dispersion spectrum of fission yeast cells in a suspension was mainly composed of two sub-dispersions. The low-frequency sub-dispersion depended on the...

Motion synchronization of multi-cylinder electro-hydraulic lift systems (2001)

Sun, Hong

In this dissertation, motion synchronization of multi-cylinder electro-hydraulic (EH) lift systems is investigated. Among the different methods of synchronizing the displacement of multiple cylinders...

Does diabetes target ganglion neurones?: Progressive sensory neurone involvement in long-term experimental diabetes (2001)

Zochodne, Douglas W., Verge, Valerie M. K., Cheng, Chu, Sun, Hong, Johnston, Jayne

Targeting of dorsal root ganglia by diabetes could account for the selective sensory abnormalities that patients with early diabetic polyneuropathy develop. In this work, we addressed survival,...

Nouvelle méthode de construction d'entrelaceurs pour les turbo codes (1999)

LE RUYET, Didier, SUN, Hong, VU THIEN, Han

Les turbo codes possèdent des performances proches des limites de Shannon mais cependant, à rapport signal à bruit élevé, ils présentent un effet de palier dû à leur faible distance minimale....

The Tumor Suppressor Protein TEP1/PTEN/MMAC1 and Human Breast Cancer (1998)

Sun, Hong

PTEN is an important tumor suppressor that is commonly mutated in a wide variety of human cancers. Recent studies have suggested that the PTEN protein can in vitro dephosphorylate...

The Tumor Suppressor Protein TEP1/PTEN/MMAC1 and Human Breast Cancer (1998)

Sun, Hong

We have previously cloned a novel protein, TEP1, also called PTEN or MMAC1, based on its sequence homology to members of protein tyrosine phosphatases. PTEN/MMAC1/TEP1 has now been well established...

The Tumor Suppressor Protein TEP1/PTEN/MMAC1 and Human Breast Cancer (1998)

Sun, Hong

PTEN is an important tumor suppressor. Both inherited mutations and somatic mutations in the PTEN gene have been frequently found in a variety of human cancers, including the breast cancer, PTEN...

TEM Observation of Microstructures in RF-Sputtered Sm-Fe Magnetic Thin Films (1996)

Sun, Hong, Itoh, Yutaka, Hanafusa, Kenji, Kamei, Kazuhito, Tomida, Toshiro

The planar-view and cross-sectional microstructures of binary Sm-Fe magnetic thin films deposited on quartz glass substrates by the RF-sputtering method are investigated using a transmission electron...

Myth and reality in the rural and urban worlds :--a survey of the literary landscape in American and Chinese regional literatures /--by Hong Sun. (1995)

Sun, Hong.

Thesis (Ph. D.)--Washington University, 1995. Dept. of Asian and Near Eastern Languages and Literatures and Committee on Comparative Literature.

Myth and reality in the rural and urban worlds :--a survey of the literary landscape in American and Chinese regional literatures /--by Hong Sun. (1995)

Sun, Hong.

Thesis (Ph. D.)--Washington University, 1995. Dept. of Asian and Near Eastern Languages and Literatures and Committee on Comparative Literature.

Magnetization and 57Fe hyperfine fields in Y2Fe17Z3- δ (Z=H, C, or N) interstitial compounds (1992)

Qi, Qi-nian, Sun, Hong, Skomski, Ralph, Coey, J.M.D.

Measured magnetization and 57Fe hyperfine fields at T∼0 K for Y2Fe17 and Y2Fe17Z3- δ , with Z=H, C, or N and δ∼0.5, are analyzed to determine the influence of the interstitial atoms on the 3d...

STRUCTURAL AND MAGNETIC PROPERTIES OF R(Ti, Fe)12 (1988)

Yang, Ying-Chang, Kong, Lin-Shu, Zha, Yuan-Bo, Sun, Hong, Pei, Xie-Di

The crystallographic and intrinsic magnetic properties of R(Ti, Fe)12, where R represents Nd, Sm, Gd, Te, Dy, Ho, Er and Y, have been investigated by X-ray diffraction and magnetic measurements. They...

STRUCTURAL AND MAGNETIC PROPERTIES OF R(Ti, Fe)12 (1988)

Yang, Ying-Chang, Kong, Lin-Shu, Zha, Yuan-Bo, Sun, Hong, Pei, Xie-Di

The crystallographic and intrinsic magnetic properties of R(Ti, Fe)12, where R represents Nd, Sm, Gd, Te, Dy, Ho, Er and Y, have been investigated by X-ray diffraction and magnetic measurements. They...

STRUCTURAL AND MAGNETIC PROPERTIES OF R(Ti, Fe)12 (1988)

Yang, Ying-Chang, Kong, Lin-Shu, Zha, Yuan-Bo, Sun, Hong, Pei, Xie-Di

The crystallographic and intrinsic magnetic properties of R(Ti, Fe)12, where R represents Nd, Sm, Gd, Te, Dy, Ho, Er and Y, have been investigated by X-ray diffraction and magnetic measurements. They...

Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms

Sun, Hong, Taneja, Reshma

Stra13 is a transcriptional repressor related within its basic helix–loop–helix domain with the Drosophila Hairy, Enhancer of Split, and the mouse Hes1 proteins that interact with the corepressor...

TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation

Heymont, Jennifer, Berenfeld, Ludmilla, Collins, Jennifer, Kaganovich, Alexandra, Maynes, Bradford, Moulin, Aaron, ...

PTEN/MMAC1/TEP1 (PTEN, phosphatase deleted on chromosome ten; MMAC1, mutated in multiple advanced cancers; TEP1, tensin-like phosphatase) is a major human tumor suppressor gene whose suppressive...

The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway

Mihaylova, Valia T., Borland, Christina Z., Manjarrez, Laura, Stern, Michael J., Sun, Hong

Inactivation of the tumor suppressor PTEN gene is found in a variety of human cancers and in cancer predisposition syndromes. Recently, PTEN protein has been shown to possess phosphatase activity on...

Effect of cellular filamentation on adventurous and social gliding motility of Myxococcus xanthus

Sun, Hong, Yang, Zhaomin, Shi, Wenyuan

Filamentous bacterial cells often provide biological information that is not readily evident in normal-size cells. In this study, the effect of cellular filamentation on gliding motility of...

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

Sun, Hong, Lesche, Ralf, Li, Da-Ming, Liliental, Joanna, Zhang, Hui, Gao, Jing, ...

To investigate the molecular basis of PTEN-mediated tumor suppression, we introduced a null mutation into the mouse Pten gene by homologous recombination in embryonic stem (ES) cells. Pten−/− ES...

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

Li, Da-Ming, Sun, Hong

PTEN/MMAC1/TEP1 is a tumor suppressor that possesses intrinsic phosphatase activity. Deletions or mutations of its encoding gene are associated with a variety of human cancers. However, very little...

C/EBPɛ mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut)

Khanna-Gupta, Arati, Zibello, Theresa, Sun, Hong, Lekstrom-Himes, Julie, Berliner, Nancy

Neutrophils from CCAAT enhancer binding protein epsilon (C/EBPɛ) knockout mice have morphological and biochemical features similar to those observed in patients with an extremely rare congenital...

Analyses of mrp Genes during Myxococcus xanthus Development

Sun, Hong, Shi, Wenyuan

Myxococcus xanthus is a gram-negative soil bacterium that undergoes development under starvation conditions. Our previous study identified a new genetic locus, mrp, which is required for both...

Genetic Studies of mrp, a Locus Essential for Cellular Aggregation and Sporulation of Myxococcus xanthus

Sun, Hong, Shi, Wenyuan

Under starvation conditions, Myxococcus xanthus undergoes a complex developmental process which includes cellular aggregation and sporulation. A transposon insertion mutant (the Tn5-Ω280 mutant)...

Extracellular polysaccharides mediate pilus retraction during social motility of Myxococcus xanthus

Li, Yinuo, Sun, Hong, Ma, Xiaoyuan, Lu, Ann, Lux, Renate, Zusman, David, ...

Myxococcus xanthus is a Gram-negative bacterium with a complex life cycle that includes vegetative swarming and fruiting-body formation. Social (S)-motility (coordinated movement of large cell...

Heme oxygenase-1 gene induction as an intrinsic regulation against delayed cerebral vasospasm in rats

Suzuki, Hidenori, Kanamaru, Kenji, Tsunoda, Hiroshi, Inada, Hiroyasu, Kuroki, Minoru, Sun, Hong, ...

Delayed cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) causes cerebral ischemia and infarction. To date, the pathogenesis and gene expression associated with vasospasm remain...

Organization of the Caenorhabditis elegans small non-coding transcriptome: Genomic features, biogenesis, and expression

Deng, Wei, Zhu, Xiaopeng, Skogerbø, Geir, Zhao, Yi, Fu, Zhuo, Wang, Yudong, ...

Recent evidence points to considerable transcription occurring in non-protein-coding regions of eukaryote genomes. However, their lack of conservation and demonstrated function have created...

Challenges of Detecting Directional Selection After a Bottleneck: Lessons From Sorghum bicolor

Hamblin, Martha T., Casa, Alexandra M., Sun, Hong, Murray, Seth C., Paterson, Andrew H., Aquadro, Charles F., ...

Multilocus surveys of sequence variation can be used to identify targets of directional selection, which are expected to have reduced levels of variation. Following a population bottleneck, the...

Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms

Sun, Hong, Taneja, Reshma

Stra13 is a transcriptional repressor related within its basic helix–loop–helix domain with the Drosophila Hairy, Enhancer of Split, and the mouse Hes1 proteins that interact with the corepressor...

TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation

Heymont, Jennifer, Berenfeld, Ludmilla, Collins, Jennifer, Kaganovich, Alexandra, Maynes, Bradford, Moulin, Aaron, ...

PTEN/MMAC1/TEP1 (PTEN, phosphatase deleted on chromosome ten; MMAC1, mutated in multiple advanced cancers; TEP1, tensin-like phosphatase) is a major human tumor suppressor gene whose suppressive...

The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway

Mihaylova, Valia T., Borland, Christina Z., Manjarrez, Laura, Stern, Michael J., Sun, Hong

Inactivation of the tumor suppressor PTEN gene is found in a variety of human cancers and in cancer predisposition syndromes. Recently, PTEN protein has been shown to possess phosphatase activity on...

Effect of cellular filamentation on adventurous and social gliding motility of Myxococcus xanthus

Sun, Hong, Yang, Zhaomin, Shi, Wenyuan

Filamentous bacterial cells often provide biological information that is not readily evident in normal-size cells. In this study, the effect of cellular filamentation on gliding motility of...

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

Sun, Hong, Lesche, Ralf, Li, Da-Ming, Liliental, Joanna, Zhang, Hui, Gao, Jing, ...

To investigate the molecular basis of PTEN-mediated tumor suppression, we introduced a null mutation into the mouse Pten gene by homologous recombination in embryonic stem (ES) cells. Pten−/− ES...

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

Li, Da-Ming, Sun, Hong

PTEN/MMAC1/TEP1 is a tumor suppressor that possesses intrinsic phosphatase activity. Deletions or mutations of its encoding gene are associated with a variety of human cancers. However, very little...

C/EBPɛ mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut)

Khanna-Gupta, Arati, Zibello, Theresa, Sun, Hong, Lekstrom-Himes, Julie, Berliner, Nancy

Neutrophils from CCAAT enhancer binding protein epsilon (C/EBPɛ) knockout mice have morphological and biochemical features similar to those observed in patients with an extremely rare congenital...

Analyses of mrp Genes during Myxococcus xanthus Development

Sun, Hong, Shi, Wenyuan

Myxococcus xanthus is a gram-negative soil bacterium that undergoes development under starvation conditions. Our previous study identified a new genetic locus, mrp, which is required for both...

Genetic Studies of mrp, a Locus Essential for Cellular Aggregation and Sporulation of Myxococcus xanthus

Sun, Hong, Shi, Wenyuan

Under starvation conditions, Myxococcus xanthus undergoes a complex developmental process which includes cellular aggregation and sporulation. A transposon insertion mutant (the Tn5-Ω280 mutant)...

Extracellular polysaccharides mediate pilus retraction during social motility of Myxococcus xanthus

Li, Yinuo, Sun, Hong, Ma, Xiaoyuan, Lu, Ann, Lux, Renate, Zusman, David, ...

Myxococcus xanthus is a Gram-negative bacterium with a complex life cycle that includes vegetative swarming and fruiting-body formation. Social (S)-motility (coordinated movement of large cell...

Heme oxygenase-1 gene induction as an intrinsic regulation against delayed cerebral vasospasm in rats

Suzuki, Hidenori, Kanamaru, Kenji, Tsunoda, Hiroshi, Inada, Hiroyasu, Kuroki, Minoru, Sun, Hong, ...

Delayed cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) causes cerebral ischemia and infarction. To date, the pathogenesis and gene expression associated with vasospasm remain...

Organization of the Caenorhabditis elegans small non-coding transcriptome: Genomic features, biogenesis, and expression

Deng, Wei, Zhu, Xiaopeng, Skogerbø, Geir, Zhao, Yi, Fu, Zhuo, Wang, Yudong, ...

Recent evidence points to considerable transcription occurring in non-protein-coding regions of eukaryote genomes. However, their lack of conservation and demonstrated function have created...

Challenges of Detecting Directional Selection After a Bottleneck: Lessons From Sorghum bicolor

Hamblin, Martha T., Casa, Alexandra M., Sun, Hong, Murray, Seth C., Paterson, Andrew H., Aquadro, Charles F., ...

Multilocus surveys of sequence variation can be used to identify targets of directional selection, which are expected to have reduced levels of variation. Following a population bottleneck, the...

Topographic organization in the auditory brainstem of juvenile mice is disrupted in congenital deafness

Leao, Richardson N, Sun, Hong, Svahn, Katarina, Berntson, Amy, Youssoufian, Monique, Paolini, Antonio G, ...

There is an orderly topographic arrangement of neurones within auditory brainstem nuclei based on sound frequency. Previous immunolabelling studies in the medial nucleus of the trapezoid body (MNTB)...

Hyperpolarization-activated currents are differentially expressed in mice brainstem auditory nuclei

Leao, Katarina E, Leao, Richardson N, Sun, Hong, Fyffe, Robert E W, Walmsley, Bruce

The hyperpolarization-activated cation current (Ih) may influence precise auditory processing by modulating resting membrane potential and cell excitability. We used electrophysiology and...

Stra13 regulates satellite cell activation by antagonizing Notch signaling

Sun, Hong, Li, Li, Vercherat, Cécile, Gulbagci, Neriman Tuba, Acharjee, Sujata, Li, Jiali, ...

Satellite cells play a critical role in skeletal muscle regeneration in response to injury. Notch signaling is vital for satellite cell activation and myogenic precursor cell expansion but inhibits...

Dried Blood Spots versus Sera for Detection of Rubella Virus-Specific Immunoglobulin M (IgM) and IgG in Samples Collected during a Rubella Outbreak in Peru▿

Helfand, Rita F., Cabezas, Cesar, Abernathy, Emily, Castillo-Solorzano, Carlos, Ortiz, Ana Cecilia, Sun, Hong, ...

Most persons with rubella virus-specific immunoglobulin M (IgM)- or IgG-positive sera tested positive (98% [n = 178] and 99% [n = 221], respectively) using paired filter paper dried blood spot (DBS)...

Stra13 is induced by genotoxic stress and regulates ionizing-radiation-induced apoptosis

Thin, Tin Htwe, Li, Li, Chung, Teng-Kai, Sun, Hong, Taneja, Reshma

In response to a number of genotoxic stimuli that induce DNA damage in cells, the tumour suppressor p53 is activated resulting in cell cycle arrest or apoptosis. In this study, we have identified...

Evidence that nitric oxide- and opioid-containing interneurons innervate vessels in the dorsal horn of the spinal cord of rats

Zochodne, Douglas W, Sun, Hong, Li, Xia-Qing

In the dorsal horn of the spinal cord, activation of small fibre nociceptive afferents leads to the release of nitric oxide and enkephalins by interneurons. In this work we encountered unexpected...

Growth factor independence-1 (Gfi-1) plays a role in mediating specific granule deficiency (SGD) in a patient lacking a gene-inactivating mutation in the C/EBPϵ gene

Khanna-Gupta, Arati, Sun, Hong, Zibello, Theresa, Lee, Han Myung, Dahl, Richard, Boxer, Laurence A., ...

Neutrophil-specific granule deficiency (SGD) is a rare congenital disorder marked by recurrent bacterial infections. Neutrophils from SGD patients lack secondary and tertiary granules and their...

Structural Relationships between Highly Conserved Elements and Genes in Vertebrate Genomes

Sun, Hong, Skogerbø, Geir, Wang, Zhen, Liu, Wei, Li, Yixue

Large numbers of sequence elements have been identified to be highly conserved among vertebrate genomes. These highly conserved elements (HCEs) are often located in or around genes that are involved...

Confirmation of Rubella within 4 Days of Rash Onset: Comparison of Rubella Virus RNA Detection in Oral Fluid with Immunoglobulin M Detection in Serum or Oral Fluid ▿

Abernathy, Emily, Cabezas, Cesar, Sun, Hong, Zheng, Qi, Chen, Min-hsin, Castillo-Solorzano, Carlos, ...

Rubella virus infection is typically diagnosed by the identification of rubella virus-specific immunoglobulin M (IgM) antibodies in serum, but approximately 50% of serum samples from rubella cases...

Arsenite alters global histone H3 methylation

Zhou, Xue, Sun, Hong, Ellen, Thomas P., Chen, Haobin, Costa, Max

Arsenic (As) is a well-characterized human carcinogen but is generally not mutagenic. The evidence that As induces both loss of global DNA methylation and gene promoter DNA hypermethylation has...

Giant Cavernous Aneurysm Associated with a Persistent Trigeminal Artery and Persistent Otic Artery

Zhang, Chang-wei, Xie, Xiao-dong, Yang, Zhi-gang, Wang, Chao-hua, You, Chao, Mao, Bo-yong, ...

Primitive trigeminal artery (PTA) and primitive otic artery (POA) is a very rare entity in adult life. We present a case of PTA and POA associated with a giant unruptured cavernous aneurysm in a...

Effects of lysophosphatidic acid on human colon cancer cells and its mechanisms of action

Sun, Hong, Ren, Juan, Zhu, Qing, Kong, Fan-Zhong, Wu, Lei, Pan, Bo-Rong

AIM: To study the effects of lysophosphatidic acid (LPA) on proliferation, adhesion, migration, and apoptosis in the human colon cancer cell line, SW480, and its mechanisms of action.