Hong Zhang

Do the mutations of C1GALT1C1gene play important roles in the genetic susceptibility to Chinese IgA nephropathy? (2009)

Li, Gui-Sen, Nie, Guang-Jun, Zhang, Hong, LV, Ji-Cheng, Shen, Yan, Wang, Hai-Yan

Abstract Background The deficiency of β 1,3 galactose in hinge region of IgA1 molecule played a pivotal role in pathogenesis of IgA nephropathy (IgAN). Cosmc, encoded by C1GALT1C1 gene, was...

Multiple-infection and recombination in HIV-1 within a longitudinal cohort of women (2009)

Templeton, Alan R, Kramer, Melissa G, Jarvis, Joseph, Kowalski, Jeanne, Gange, Stephen, Schneider, Michael F, ...

Abstract Background Recombination between strains of HIV-1 only occurs in individuals with multiple infections, and the incidence of recombinant forms implies that multiple infection is common. Most...

Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis (2009)

Sorci, Leonardo, Martynowski, Dariusz, Rodionov, Dmitry A., Eyobo, Yvonne, Zogaj, Xhavit, Klose, Karl E., ...

Enzymes involved in the last 2 steps of nicotinamide adenine dinucleotide (NAD) cofactor biosynthesis, which catalyze the adenylylation of the nicotinic acid mononucleotide (NaMN) precursor to...

Polysialic Acid Is Required for Optimal Growth of Axons on a Neuronal Substrate (2009)

Hong Zhang, Robert H. Miller, Urs Rutishauserv

Formation of axonal pathways involves a variety of mole-cules that influence cell-cell interactions. The polysialic acid (PSA) moiety of the neural cell adhesion molecule (NCAM) is present on...

Regulation of Skeletal Muscle Development And Differentiation by Ski (2009)

Zhang, Hong

Ski is the most studied member of a family of proteins all sharing a conserved Dachshund homology domain. It has been implicated in oncogenic transformation, myogenic conversion of avian embryo...

Regulation of Skeletal Muscle Development And Differentiation by Ski (2009)

Zhang, Hong

Ski is the most studied member of a family of proteins all sharing a conserved Dachshund homology domain. It has been implicated in oncogenic transformation, myogenic conversion of avian embryo...

Di-μ-bromido-tris(triphenylphosphine)-1κP,2κ2P-disilver(I) tetrahydrofuran 0.85-solvate (2009)

Weiping Gao, Yanhong Zhou, Hong Zhang

In the title binuclear silver(I) complex, [Ag2Br2(C18H15P)3]·0.85C4H8O, the two independent silver(I) ions are briged by two bromide ions. One AgI ion is coordinated by two triphenylphosphine...

Inhibitory Effects of Morinda officinalis Extract on Bone Loss in Ovariectomized Rats (2009)

Nan Li, Lu-Ping Qin, Ting Han, Yan-Bin Wu, Qiao-Yan Zhang, Hong Zhang

The present study was undertaken to investigate the protective effects of ethanol extract from the root of Morinda Officinalis (RMO) on ovariectomy-induced bone loss. Administration of RMO extract...

Poly[4-(dimethylamino)pyridinium [(μ6-5-carboxybenzene-1,2,4-tricarboxyato-κ6O1:O1′:O2:O4:O4′:O5)diargentate(I)]] (2009)

Xiao-Fei Zhu, Yan-Hong Zhou, Li Guan, Hong Zhang

In the title compound, {(C7H11N2)[Ag2(C10H3O8)]}n, the polymeric anion consists of two AgI atoms and a Hbtc3− ligand (H4btc = benzene-1,2,4,5-tetracarboxylic acid). Each AgI atom is coordinated...

Positive feedback regulation of maize NADPH oxidase by mitogen-activated protein kinase cascade in abscisic acid signalling (2009)

Lin, Fan, Ding, Haidong, Wang, Jinxiang, Zhang, Hong, Zhang, Aying, Zhang, Yun, ...

In maize (Zea mays), abscisic acid (ABA)-induced H2O2 production activates a 46 kDa mitogen-activated protein kinase (p46MAPK), and the activation of p46MAPK also regulates the production of H2O2....

Numerical Study of the Hydrodynamics of a Very Shallow Estuarine System - Coombabah Lake, Gold Coast, Australia (2009)

Ali, Ayub, Zhang, Hong, Lemckert, Charles James

Coastal wetlands and estuaries are important environments providing significant habitats for flora and fauna species - often supporting commercial and recreational fisheries. These systems also act...

Numerical Study of the Hydrodynamics of a Very Shallow Estuarine System - Coombabah Lake, Gold Coast, Australia (2009)

Ali, Ayub, Zhang, Hong, Lemckert, Charles James

Coastal wetlands and estuaries are important environments providing significant habitats for flora and fauna species - often supporting commercial and recreational fisheries. These systems also act...

Aberrant galactosylation of IgA1 is involved in the genetic susceptibility of Chinese patients with IgA nephropathy (2009)

Lin, Xiaojie, Ding, Jiaxiang, Zhu, Li, Shi, Sufang, Jiang, Lei, Zhao, Minghui, ...

Background. Immunoglobulin A nephropathy (IgAN) is associated with genetic and environmental factors, and undergalactosylation of IgA1 in the serum is considered to be a contributor to pathogenesis...

Wind wave effects on hydrodynamic modeling of ocean circulation in the South China Sea (2009)

Zhang, Hong, Sannasiraj, S.A., Chan, Eng Soon

Wind, wave and current interactions control the boundary fluxes, momentum and energy exchange between the atmosphere and the ocean, and within the water column. The wind wave effect on the...

Wind wave effects on hydrodynamic modeling of ocean circulation in the South China Sea (2009)

Zhang, Hong, Sannasiraj, S.A., Chan, Eng Soon

Wind, wave and current interactions control the boundary fluxes, momentum and energy exchange between the atmosphere and the ocean, and within the water column. The wind wave effect on the...

Abstract Forming an IPv6-only Core for Today’s Internet (2008)

Hong Zhang

Routing complexity of the core network is crucial to Internet scalability. IPv6 is believed to have better performance in multihoming than conventional IPv4. With the depolyment of native IPv6...

A Panoramic Model for Remote Robot Environment Mapping and Predictive Display (2008)

Dana Cobzas, Martin Jägers, Hong Zhang

Abstract: Robot tele-operation is significantly degraded by delays in the operator visual feedback. We present a cylindrical image-depth model that can be automatically acquired at the remote work...

Multi-Robot Collective Sorting with Local Sensing (2008)

Tao Wang, Hong Zhang

Abstract – In this paper, we present an ant inspired approach to object sorting problem with multiple robots. Our approach to this problem is general in the sense of that it does not require any...

1 Introduction Collective Robotic Site Preparation (2008)

Hong Zhang

Robotic site preparation has been identified as an integral precursor to human landings on Mars.

A Fast and Effective Model for Wavelet Subband Histograms and Its Application in Texture Image Retrieval (2008)

Ming Hong Pi, C. S. Tong, Siu Kai Choy, Hong Zhang

Abstract—This paper presents a novel, effective, and efficient characterization of wavelet subbands by bit-plane extractions. Each bit plane is associated with a probability that represents the...

abf-1 and abf-2, ASABF-type antimicrobial peptide genes in (2008)

Caenorhabditis Elegans, Yusuke Kato, Tomoyasu Aizawa, Hirokazu Hoshino, Keiichi Kawano, Katsutoshi Nitta, ...

factor)-type antimicrobial peptide, abf-1 and abf-2, were identified in Caenorhabditis elegans. Recombinant ABF-2 exhibited potent microbicidal activity against Gram-positive and Gramnegative...

The Human Immunodeficiency Virus Type 1 Envelope Confers Higher Rates of Replicative Fitness to Perinatally Transmitted Viruses than to Nontransmitted Viruses (2008)

Kong, Xiaohong, West, John, Zhang, Hong, Shea, Danielle, M'Soka, Tendai J., Wood, Charles

Selection of a minor viral genotype during perinatal transmission of human Immunodeficiency virus type 1 (HIV-1) has been observed, but there is a lack of information on the correlation of the...

Neutralization-Sensitive R5 SHIV-2873Nip Encoding env from a Infant with Recent HIV Clade C Infection (2008)

Siddappa, Nagadenahalli B., Song, Ruijiang, Kramer, Victor G., Chenine, Agnes-Laurence, Velu, Vijayakumar, Ong, Helena, ...

HIV-C (HIV-C) accounts for >56% of all HIV infections worldwide. To investigate vaccine safety and efficacy in non-human primates, a pathogenic, R5-tropic, neutralization sensitive simian-human...

Feature Initialization for Bearing-Only Visual SLAM Using Triangulation and the Unscented Transform (2008)

Hong Zhang

Abstract — We introduce the direct linear triangulation (DLT) as a general technique for delayed feature initialization for bearing-only visual Simultaneous Localization and Mapping (SLAM). Visual...

Evaluation of the new rural cooperative medical system in China: is it working or not? (2008)

Dib, Hassan H, Pan, Xilong, Zhang, Hong

Abstract Background To prove the possibility of implementing the New Rural Cooperative Medical System (NRCMS) at different levels with a premium funding according to their economic level in developed...

Novel interface-selected waves and their influences on wave competitions (2008)

Cui, Xiaohua, Huang, Xiaoqing, Cao, Zhoujian, Zhang, Hong, Hu, Gang

The topic of interface effects in wave propagation has attracted great attention due to their theoretical significance and practical importance. In this paper we study nonlinear oscillatory systems...

Synthesis and optical properties of type IICdTe/CdS core/shell quantum dots in aqueous solution via successive ion layer adsorption and reaction (2008)

Zeng, Qinghui, Kong, Xianggui, Sun, Yajuan, Zhang, Youlin, Tu, Langping, Zhao, Jialong, ...

3-Mercaptopropionic acid stabilized CdTe/CdS core/shell quantum dots (QDs) were prepared in an aqueous solution following the synthetic route of successive ion layer adsorption and reaction. The...

The NEI/NCBI dbGAP database: Genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration (2008)

Zhang, Hong, Morrison, Margaux A, DeWan, Andy, Adams, Scott, Andreoli, Michael, Huynh, Nancy, ...

Abstract Background To examine if the significantly associated SNPs derived from the genome wide allelic association study on the AREDS cohort at the NEI (dbGAP) specifically confer risk for...

Presence of qnrgene in Escherichia coliand Klebsiella pneumoniaeresistant to ciprofloxacin isolated from pediatric patients in China (2008)

Wang, Aihua, Yang, Yonghong, Lu, Quan, Wang, Yi, Chen, Yuan, Deng, Li, ...

Abstract Background Quinolone resistance in Enterobacteriaceae results mainly from mutations in type II DNA topoisomerase genes and/or changes in the expression of outer membrane and efflux pumps....

Research Track Paper On the Discovery of Significant Statistical Quantitative (2008)

Hong Zhang

In this paper we study market share rules, rules that have a certain market share statistic associated with them. Such rules are particularly relevant for decision making from a business perspective....

Numerical condition of polynomials in different forms (2008)

Hong Zhang

Abstract. The zeros of high-degree polynomials are notoriously sensitive to changes in the coefficients, causing problems for available zero-finding software. In this paper, we study how this...

A Bookkeeping Strategy for Multiple Objective Linear Programs (2008)

Alok Aurovillian, Hong Zhang, Malgorzata M. Wiecek

This paper discusses the bookkeeping strategies for solving large multiple objective linear programs �MOLPs � on ADBASE, a well developed sequential software package, and on a parallel ADBASE...

Article electronically published on May 15, 2002 PSEUDOZEROS OF MULTIVARIATE POLYNOMIALS (2008)

J. William Hoffman, James J. Madden, Hong Zhang

Abstract. The pseudozero set of a system f of polynomials in n complex variables is the subset of C n which is the union of the zero-sets of all polynomial systems g that are near to f in a suitable...

A PANORAMIC MODEL FOR REMOTE ROBOT ENVIRONMENT MAPPING AND PREDICTIVE DISPLAY Abstract (2008)

Martin Jägers, Hong Zhang

Robot tele-operation is significantly degraded by delays in the operator visual feedback. We present a cylindrical image-depth model that can be easily acquired at the remote work site and then used...

Abstract Predictive Windows for Delay Compensation in Applications * (2008)

Jonathan Baldwin, Anup Basu, Hong Zhang

Predictive Kalman filters can be used to predict positions of a mouse when it is operated under some basic assumptions. This prediction can be used to estimate what portions of a larger image an...

Nanocrystalline diamond films deposited by the hot cathode direct current plasma chemical vapor deposition method with different compositions of CH4/Ar/H-2 gas mixture (2008)

Zeng, Leyong, Peng, Hongyan, Wang, Weibiao, Chen, Yuqiang, Lei, Da, Qi, Wentao, ...

Nanocrystalline diamond films with different grain sizes were synthesized on Si substrate by the hot cathode direct current plasma chemical vapor deposition method with different compositions of...

Collaborate on an Interdisciplinary Project (2008)

Session Tb, Adrian Rusu, Amalia Rusu, Jennifer Kay, Hong Zhang

technology education in elementary and secondary schools, K-12 students and their teachers have participated in a variety of outreach programs. However, the majority of these programs have focused on...

Improvement of an Artificial Neural Network Model using Min- Max Preprocessing for the Prediction of Wave-induced Seabed (2008)

Deaho Cha, Michael Blumenstein, Hong Zhang, Dong-sheng Jeng

Abstract—In the past decade, artificial neural networks (ANNs) have been widely applied to the engineering problems with a complicated system. ANNs are becoming an important alternative option for...

c ○ 1997 Kluwer Academic Publishers. Manufactured in The Netherlands. Task Modelling in Collective Robotics (2008)

C. Ronald, Hong Zhang

Abstract. Does coherent collective behaviour require an explicit mechanism of cooperation? In this paper, we demonstrate that a certain class of cooperative tasks, namely coordinated box...

Abstract Panoramic Video wit h Predictive Windows for Telepresence Applications (2008)

Jonathan Baldwin, Anup Basu, Hong Zhang

In this paper we describe the application of a predictive Kalman filter to the display of panoramic images. We discuss integrating a panoramic imaging system with prediction of viewing direction to...

A Neural-Genetic Technique for Coastal Engineering: Determining Wave-induced Seabed Liquefaction (2008)

Daeho Cha, Michael Blumenstein, Hong Zhang, Dong-sheng Jeng, Daeho Cha, Michael Blumenstein, ...

In the past decade, computational intelligence (CI) techniques have been widely adopted in various fields such as business, science and engineering, as well as information technology. Specifically,...

The effects of organizational supports in the estimation process on the stress of construction cost engineers (2008)

Leung, Mei-Yung, Zhang, Hong, Skitmore, Martin

Forecasting the likely cost of construction work prior to tendering is well known as a hazardous task. Underestimates cause financial difficulties for clients and contractors with limited budgets and...

The effects of organizational supports in the estimation process on the stress of construction cost engineers (2008)

Leung, Mei-Yung, Zhang, Hong, Skitmore, Martin

Forecasting the likely cost of construction work prior to tendering is well known as a hazardous task. Underestimates cause financial difficulties for clients and contractors with limited budgets and...

Radio frequency analog electronics based on carbon nanotube transistors (2008)

Kocabas, Coskun, Kim, Hoon-sik, Banks, Tony, Rogers, John A., Pesetski, Aaron A., Baumgardner, James E., ...

The potential to exploit single-walled carbon nanotubes (SWNTs) in advanced electronics represents a continuing, major source of interest in these materials. However, scalable integration of SWNTs...

A Constraint-Satisfaction Approach for 3-D Object Recognition by Integrating 2-D and 3-D Data (2008)

Michael Boshra, Hong Zhang

We present a framework for recognition of 3-D objects by integrating 2-D and 3-D sensory data. The major thrust of this work is to efficiently utilize all relevant data, both 2-D and 3-D, in the...

Ginsenoside $R_e$ Increases Fertile and Asthenozoospermic Infertile Human Sperm Motility by Induction of Nitric Oxide Synthase (2008)

Zhang, Hong, Zhou, Qing-Ming, Li, Xiao-Da, Xie, Yi, Duan, Xin, Min, Feng-Ling, ...

We investigated the effects of Ginsenoside $R_e$ on human sperm motility in fertile and asthenozoospermic infertile individuals in vitro and the mechanism by which the Ginsenosides play their roles....

Customer retention in the financial industry: An application of survival analysis (2008)

Zhang, Hong

Recently, in both marketing theory (academia) and practice (industry), the emphasis in relationship marketing has shifted to long term customer relationship management emphasizing customer retention...

The effects of organizational supports in the estimation process on the stress of construction cost engineers (2008)

Leung, Mei-Yung, Zhang, Hong, Skitmore, Martin

Forecasting the likely cost of construction work prior to tendering is well known as a hazardous task. Underestimates cause financial difficulties for clients and contractors with limited budgets and...

Heterogeneous Stacking for Classification-Driven Watershed Segmentation (2008)

Ilya Levner, Hong Zhang, Russell Greiner

Marker-driven watershed segmentation attempts to extract seeds that indicate the presence of objects within an image. These markers are subsequently used to enforce regional minima within a...

The effects of organizational supports in the estimation process on the stress of construction cost engineers (2008)

Leung, Mei-Yung, Zhang, Hong, Skitmore, Martin

Forecasting the likely cost of construction work prior to tendering is well known as a hazardous task. Underestimates cause financial difficulties for clients and contractors with limited budgets and...

Quantum dynamical study of the O(1D)+HCl reaction employing three electronic state potential energy surfaces (2008)

Yang, Huan, Han, Ke-Li, Nanbu, Shinko, Nakamura, Hiroki, Balint-Kurti, Gabriel G., Zhang, Hong, ...

Quantum dynamical calculations are reported for the title reaction, for both product arrangement channels and using potential energy surfaces corresponding to the three electronic states, 1...

Quantum Mechanical Calculation of Energy Dependence of OCl/OH Product Branching Ratio and Product Quantum State Distributions for the O(1D) + HCl Reaction on All Three Contributing Electronic State Potential Energy Surfaces (2008)

Yang, Huan, Han, Ke-Li, Nanbu, Shinkoh, Nakamura, Hiroki, Balint-Kurti, Gabriel G., Zhang, Hong, ...

OCl/OH product branching ratios are calculated as a function of total energy for the O(1D) + HCl reaction using quantum wavepacket methods. The calculations take account of reaction on all the three...

Quantum Calculation of Ro-vibrational States: Methodology and DOCl Application Results (2008)

Zhang, Hong, Hankel, Marlies, Smith, Sean C., Nanbu, Shinkoh, Nakamura, Hiroki

An improved Lanczos eigenvalue analysis method has been developed to compute the bound ro-vibrational states for the DOCl system at a total angular momentum of J = 0 and J = 30. In this method, the...

Potential Mechanisms Involved in Resistant Phenotype of MCF-7 Breast Carcinoma Cells to Ionizing Radiation-Induced Apoptosis (2008)

Wang, Yan-Lin, Zhang, Hong, Li, Ning, Wang, Xiaohu, Hao, Ji-Fang, Zhao, Wei-Ping

We investigated the mechanisms of apoptosis resistance and the roles of the phosphorylation of BRCA1, p21, the Bax/Bcl-2 protein ratio and cell cycle arrest induced by irradiation in MCF-7 cells....

Potential Mechanisms Involved in Resistant Phenotype of MCF-7 Breast Carcinoma Cells to Ionizing Radiation-Induced Apoptosis (2008)

Wang, Yan-Lin, Zhang, Hong, Li, Ning, Wang, Xiaohu, Hao, Ji-Fang, Zhao, Wei-Ping

We investigated the mechanisms of apoptosis resistance and the roles of the phosphorylation of BRCA1, p21, the Bax/Bcl-2 protein ratio and cell cycle arrest induced by irradiation in MCF-7 cells....

Impact of the method of cooling blood to remove stasis on tumor necrosis factor-alpha and interleukin-10 mRNA expressions in peripheral blood mononuclear cells of rats with experimental autoimmune thyroiditis (2008)

Hong ZHANG, Jun GU

Objective: To explore the effects of Liangxue Huayu therapy (LXHYT), a traditional Chinese herbal therapy for cooling blood and dissipating blood stasis, on rat model of experimental autoimmune...

The effects of organizational supports in the estimation process on the stress of construction cost engineers (2008)

Leung, Mei-Yung, Zhang, Hong, Skitmore, Martin

Forecasting the likely cost of construction work prior to tendering is well known as a hazardous task. Underestimates cause financial difficulties for clients and contractors with limited budgets and...

The effects of organizational supports in the estimation process on the stress of construction cost engineers (2008)

Leung, Mei-Yung, Zhang, Hong, Skitmore, Martin

Forecasting the likely cost of construction work prior to tendering is well known as a hazardous task. Underestimates cause financial difficulties for clients and contractors with limited budgets and...

Quantum dynamical study of the O(1D)+HCl reaction employing three electronic state potential energy surfaces (2008)

Yang, Huan, Han, Ke-Li, Nanbu, Shinko, Nakamura, Hiroki, Balint-Kurti, Gabriel G., Zhang, Hong, ...

Quantum dynamical calculations are reported for the title reaction, for both product arrangement channels and using potential energy surfaces corresponding to the three electronic states, 1...

Quantum Mechanical Calculation of Energy Dependence of OCl/OH Product Branching Ratio and Product Quantum State Distributions for the O(1D) + HCl Reaction on All Three Contributing Electronic State Potential Energy Surfaces (2008)

Yang, Huan, Han, Ke-Li, Nanbu, Shinkoh, Nakamura, Hiroki, Balint-Kurti, Gabriel G., Zhang, Hong, ...

OCl/OH product branching ratios are calculated as a function of total energy for the O(1D) + HCl reaction using quantum wavepacket methods. The calculations take account of reaction on all the three...

Quantum Calculation of Ro-vibrational States: Methodology and DOCl Application Results (2008)

Zhang, Hong, Hankel, Marlies, Smith, Sean C., Nanbu, Shinkoh, Nakamura, Hiroki

An improved Lanczos eigenvalue analysis method has been developed to compute the bound ro-vibrational states for the DOCl system at a total angular momentum of J = 0 and J = 30. In this method, the...

Computing oil sand particle size distribution by snake-PCA algorithm,” accepted at (2008)

Baidya Nath Saha, Nilanjan Ray, Hong Zhang

An important measure in various stages of oil sand mining is particle size distribution (PSD). Currently PSD is found by time consuming manual inspection. An effective automation of PSD computation...

Molecular dynamic simulations of interactions between LDH and NOˉ3 intercalates in aqueous solution (2008)

Tran, Pierre, Sean Smith, Zhang, Hong, Xu, Zhi P., Yunyi Wong, Lu, Gaoqing

Using the formula of hydrotalcite-like compounds Mg1−xAlx(OH)2(NO3)x·nH2O, we followed the conformational changes for different models varying the ratio of Al3+. This is the first attempt to study...

Numerical study on the summer upwelling system in the northern continental shelf of the South China Sea (2008)

Jing, Zhi-you, Qi, Yi-quan, Hua, Zu-lin, Zhang, Hong

A three-dimensional baroclinic nonlinear numerical model is employed to investigate the summer upwelling in the northern continental shelf of the South China Sea (NCSCS) and the mechanisms of the...

Wind Wave Effects On Surface Stress In Hydrodynamic Modeling (2008)

Zhang, Hong, Sannasiraj, S.A.

Wind, wave and current interactions control the boundary fluxes, momentum and energy exchange between the atmosphere and the ocean, and within the water column. The wind wave effect on surface stress...

Sustainability of reclaimed foreshore – case study: Southport Broadwater Parklands (2008)

Fernagu, Eric Marie Denis, Zhang, Hong, Tomlinson, Rodger Benson

The sustainability of an upcoming reclamation project at Southport Parklands on the Gold Coast, Australia, was assessed. Southport Parklands has been under development for a long time, which led to...

A note on withdrawal from a two-layer fluid through a line sink in a porous medium (2008)

Hocking, G. C., Zhang, Hong

The steady response of the free surface of a fluid in a porous medium is considered during extraction of the fluid through a line sink. A conformal-mapping approach is used to derive exact solutions...

Numerical study on the summer upwelling system in the northern continental shelf of the South China Sea (2008)

Jing, Zhi-you, Qi, Yi-quan, Hua, Zu-lin, Zhang, Hong

A three-dimensional baroclinic nonlinear numerical model is employed to investigate the summer upwelling in the northern continental shelf of the South China Sea (NCSCS) and the mechanisms of the...

A note on withdrawal from a two-layer fluid through a line sink in a porous medium (2008)

Hocking, G. C., Zhang, Hong

The steady response of the free surface of a fluid in a porous medium is considered during extraction of the fluid through a line sink. A conformal-mapping approach is used to derive exact solutions...

Wind Wave Effects On Surface Stress In Hydrodynamic Modeling (2008)

Zhang, Hong, Sannasiraj, S.A.

Wind, wave and current interactions control the boundary fluxes, momentum and energy exchange between the atmosphere and the ocean, and within the water column. The wind wave effect on surface stress...

Sustainability of reclaimed foreshore – case study: Southport Broadwater Parklands (2008)

Fernagu, Eric Marie Denis, Zhang, Hong, Tomlinson, Rodger Benson

The sustainability of an upcoming reclamation project at Southport Parklands on the Gold Coast, Australia, was assessed. Southport Parklands has been under development for a long time, which led to...

Numerical study on the summer upwelling system in the northern continental shelf of the South China Sea (2008)

Jing, Zhi-you, Qi, Yi-quan, Hua, Zu-lin, Zhang, Hong

A three-dimensional baroclinic nonlinear numerical model is employed to investigate the summer upwelling in the northern continental shelf of the South China Sea (NCSCS) and the mechanisms of the...

A note on withdrawal from a two-layer fluid through a line sink in a porous medium (2008)

Hocking, G. C., Zhang, Hong

The steady response of the free surface of a fluid in a porous medium is considered during extraction of the fluid through a line sink. A conformal-mapping approach is used to derive exact solutions...

Wind Wave Effects On Surface Stress In Hydrodynamic Modeling (2008)

Zhang, Hong, Sannasiraj, S.A.

Wind, wave and current interactions control the boundary fluxes, momentum and energy exchange between the atmosphere and the ocean, and within the water column. The wind wave effect on surface stress...

Sustainability of reclaimed foreshore – case study: Southport Broadwater Parklands (2008)

Fernagu, Eric Marie Denis, Zhang, Hong, Tomlinson, Rodger Benson

The sustainability of an upcoming reclamation project at Southport Parklands on the Gold Coast, Australia, was assessed. Southport Parklands has been under development for a long time, which led to...

The effects of organizational supports in the estimation process on the stress of construction cost engineers (2008)

Leung, Mei-Yung, Zhang, Hong, Skitmore, Martin

Forecasting the likely cost of construction work prior to tendering is well known as a hazardous task. Underestimates cause financial difficulties for clients and contractors with limited budgets and...

A better block partition and ligation strategy for individual haplotyping (2008)

Zhao, Yuzhong, Xu, Yun, Wang, Zhihao, Zhang, Hong, Chen, Guoliang

Motivation: Haplotype played an important role in the association studies of disease gene and drug responsivity over the past years, but the low throughput of expensive biological experiments largely...

Concerns of using sialidase fusion protein as an experimental drug to combat seasonal and pandemic influenza (2008)

Zhang, Hong

Sialidase fusion protein is reported to have great potential to combat seasonal and pandemic influenza, because it may prevent influenza virus infection by removing all sialic acid receptors from...

Transcriptional regulation of NAD metabolism in bacteria: genomic reconstruction of NiaR (YrxA) regulon (2008)

Rodionov, Dmitry A., Li, Xiaoqing, Rodionova, Irina A., Yang, Chen, Sorci, Leonardo, Dervyn, Etienne, ...

A comparative genomic approach was used to reconstruct transcriptional regulation of NAD biosynthesis in bacteria containing orthologs of Bacillus subtilis gene yrxA, a previously identified...

Transcriptional regulation of NAD metabolism in bacteria: NrtR family of Nudix-related regulators (2008)

Rodionov, Dmitry A., De Ingeniis, Jessica, Mancini, Chiara, Cimadamore, Flavio, Zhang, Hong, Osterman, Andrei L., ...

A novel family of transcription factors responsible for regulation of various aspects of NAD synthesis in a broad range of bacteria was identified by comparative genomics approach. Regulators of this...

Heterogeneous Stacking for Classification-Driven Watershed Segmentation (2008)

Ilya Levner, Hong Zhang, Russell Greiner

Marker-driven watershed segmentation attempts to extract seeds that indicate the presence of objects within an image. These markers are subsequently used to enforce regional minima within a...

Delayed severe pneumonia in mycophenolate mofetil-treated patients with IgA nephropathy (2008)

Lv, Jicheng, Zhang, Hong, Cui, Zhao, Su, Tao, Zhang, Yimiao, Wang, Haiyan

Background. Mycophenolate mofetil (MMF), a relatively new immunosuppressant, is widely used in the field of transplantation and also for autoimmune diseases with good tolerance. It has been reported...

Estimating the Dynamics of Mutual Fund Alphas and Betas (2008)

Mamaysky, Harry, Spiegel, Matthew, Zhang, Hong

This article develops a Kalman filter model to track dynamic mutual fund factor loadings. It then uses the estimates to analyze whether managers with market-timing ability can be identified ex ante....

Malignant hypertension in IgA nephropathy was not associated with background pathological phenotypes of glomerular lesions (2008)

Jiang, Lei, Zhang, Jun-jun, Lv, Ji-cheng, Liu, Gang, Zou, Wan-zhong, Zhao, Ming-hui, ...

Background. It was reported that IgA nephropathy (IgAN) was the major cause of secondary malignant hypertension (MHT). However, the pathogenesis of MHT secondary to IgAN (IgAN-MHT) is unknown and its...

The effects of organizational supports in the estimation process on the stress of construction cost engineers (2008)

Leung, Mei-Yung, Zhang, Hong, Skitmore, Martin

Forecasting the likely cost of construction work prior to tendering is well known as a hazardous task. Underestimates cause financial difficulties for clients and contractors with limited budgets and...

Structure Determination of a Criterion Function by Dynamic Inverse Optimization (2007)

Hong Zhang, Masumi Ishikawa

In this paper, we propose a novel approach to dynamic inverse optimization by the learning of neural networks. A dynamic inverse optimization problem here means to estimate a criterion function under...

A NOTE ON WINDOWING FOR THE WAVEFORM RELAXATION (2007)

Hong Zhang

The technique of windowing has been often used in the implementation of the waveform relaxations for solving ODEs or time dependent PDEs. Its efficiency depends upon problem stiffness and operator...

Sensing Contact with Analog Resistive Technology (2007)

Eric So Hong, Hong Zhang, Yi-sheng Guan

In this paper, we introduce a new touch sensor design, which we refer to as hybrid tactile sensor. It combines the simplicity of analog touch sensing, which is widely used in electronic touch screens...

Sensing Contact Forces in a Dexterous Hand (2007)

Yisheng Guan And, Yisheng Guan, Hong Zhang

In this paper, we describe a novel approach to sensing contact forces in a dexterous hand indirectly by combining information from distributed contact location sensors, joint torque sensors, and...

Accommodating Uncertainty in Pixel-Based Verification of 3-D Object Hypotheses (2007)

Michael Boshra, Hong Zhang

: We present a novel technique for verifying 3-D object hypotheses using an intensity image. Verification is performed through pixel-wise comparison of edge images corresponding to scene data and...

A Bookkeeping Strategy for Multiple Objective Linear Programs (2007)

Alok Aurovillian Hong, Hong Zhang, Malgorzata M. Wiecek

This paper discusses the bookkeeping strategies for solving large multiple objective linear programs (MOLPs) on ADBASE, a well developed sequential software package, and on a parallel ADBASE...

Localizing a Polyhedral Object in a Robot Hand by Integrating Visual and Tactile Data (2007)

Michael Boshra, Hong Zhang

: We present a novel technique for localizing a polyhedral object in a robot hand by integrating visual and tactile data. Localization is performed by matching a hybrid set of visual and tactile...

Efficient Edge Detection from Tactile Data (2007)

Ning Chen, Ray Rink, Hong Zhang

A real-time tactile image processing algorithm for edge contact is presented in this paper. Based on basic elasticity results, closed-form solutions for calculating contact force and local contact...

Precoded OFDM with Adaptive Vector Channel Allocation for Scalable Video Transmission over Frequency-Selective Fading Channels (2007)

Hong Zhang, Xiang-gen Xia, Qian Zhang, Wenwu Zhu

The precoded orthogonal frequency division multiplexing (OFDM) system with adaptive vector channel allocation can provide more protection against errors to more important layers in the layered bit...

Fourier-Laplace Analysis of Multigrid Waveform Relaxation Method for Hyperbolic Equations (2007)

Hong Zhang

The multigrid waveform relaxation (WR) algorithm has been fairly studied and implemented for parabolic equations. It has been found that the performance of the multigrid WR method for a parabolic...

Hybrid Tactile Sensing: Turning Garbage Bags into Tactile Sensors (2007)

Hong Zhang, Eric So

In this paper, we introduce a new touch sensor design, which we refer to as hybrid tactile sensing. Hybrid tactile sensing combines the simplicity of analog touch sensing, which is widely used in...

Assembly of myoglobin layer-by-layer films with poly(propyleneimine) dendrimer-stabilized gold nanoparticles and its application in electrochemical biosensing (2007)

Zhang, Hong, Hu, Naifei

The small-sized Au nanoparticles (3 nm) were prepared by reduction of HAuCl4 in the presence of poly(propyleneimine) (PPI) dendrimers, forming the stable PPI-Au nanoclusters in aqueous medium. The...

Improved Forecasting of Mutual Fund Alphas and Betas (2007)

Mamaysky, Harry, Spiegel, Matthew, Zhang, Hong

This paper proposes a simple back testing procedure that is shown to dramatically improve a panel data model's ability to produce out of sample forecasts. Here the procedure is used to forecast...

Negative phase velocity in nonlinear oscillatory systems --mechanism and parameter distributions (2007)

Cao, Zhoujian, Li, Pengfei, Zhang, Hong, Hu, Gang

Waves propagating inwardly to the wave source are called antiwaves which have negative phase velocity. In this paper the phenomenon of negative phase velocity in oscillatory systems is studied on the...

FSH stimulates the expression of the ADAMTS-16 protease in mature human ovarian follicles (2007)

Gao, Shuping, De Geyter, Christian, Kossowska, K., Zhang, Hong

We report the characterization of full-length human ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-16, a novel member of the disintegrin and metalloproteinase with...

中国のFTA戦略 (2007)

張, 鴻, Zhang, Hong

In the tide of regional economic integration of the world, China, which exceptionally lagged in FTA negotiation, strengthens its effort on FTA negotiation. At present, arrangement on the close trade...

Molecular epidemiology of measles viruses in China, 1995–2003 (2007)

Zhang, Yan, Zhu, Zhen, Rota, Paul A, Jiang, Xiaohong, Hu, Jiayu, Wang, Jianguo, ...

Abstract This report describes the genetic characterization of 297 wild-type measles viruses that were isolated in 24 provinces of China between 1995 and 2003. Phylogenetic analysis of the N gene...

Negative refraction in nonlinear wave systems (2007)

Cao, Zhoujian, Zhang, Hong, Hu, Gang

People have been familiar with the phenomenon of wave refraction for several centuries. Recently, a novel type of refraction, i.e., negative refraction, where both incident and refractory lines...

A meta-analysis: Obesity and colorectal cancer screening (2007)

Zhang, Hong

Of cancer death, colorectal cancer death ranks second in the United States. Obesity is an important risk factor for colorectal cancer (1). Early detection of colorectal cancer when it is localized...

Convergence behaviour of solutions to delay cellular neural networks with non-periodic coefficients (2007)

Bing Xiao, Hong Zhang

In this note we studied delay neural networks without periodic coefficients. Sufficient conditions are established to ensure that all solutions of the networks converge to a periodic function. An...

Importance of polymorphisms at NF-κB1 and NF-κBIα genes in melanoma risk, clinicopathological features and tumor progression in Swedish melanoma patients (2007)

Bu, Huajie, Rosdahl, Inger, Sun, XiaoFeng, Holmdahl-Källenand, Katarina, Zhang, Hong

In this study, functional polymorphisms of NF-κB1 and NF-κBIα genes were examined in 185 melanoma patients and 438 tumor-free individuals. Associations of the polymorphisms with melanoma risk, age...

Application of artificial neural networks in flow discharge prediction for the Fitzroy River, Australia (2007)

Joorabchi, Amirhassan, Zhang, Hong, Blumenstein, Michael Myer

Prediction of flow discharge, and in particular floods, in rivers is one of the basic and key information in regards to operation and management of the river systems. The Fitzroy River, one of the...

Impacts of uncontrolled discharge of acid rock drainage from Mount Morgan Minesite on Dee River (2007)

Tarakemeh, N., Zhang, Hong, Yu, Bofu, McCombe, C.

Uncontrolled discharge of Acid Rock Drainage (ARD) from Mount Morgan mine site accumulated over time poses significant environmental risk on the Dee River downstream. This paper investigates and flow...

Summer Upwelling in the Northern Continental Shelf of the South China Sea (2007)

Jing, Zhiyou, Hua, Z. L., Qi, Y. Q., Zhang, Hong

Summer upwelling system in the northern continental shelf of the South China Sea (NCSCS) is investigated with the Pathfinder, Advanced Very High Resolution Radiometer (AVHRR) Sea Surface Temperature...

Parametric study on the Prediction of Wave-induced Liquefaction using an Artificial Neural Network Model (2007)

Zhang, Hong, Jeng, Dong-Sheng, Cha, Deaho Fred, Blumenstein, Michael Myer

The prediction of the wave-induced liquefaction potential is particularly important for coastal engineers involved in the design of marine structures. An artificial neural network (ANN) model is used...

Application of artificial neural networks in flow discharge prediction for the Fitzroy River, Australia (2007)

Joorabchi, Amirhassan, Zhang, Hong, Blumenstein, Michael Myer

Prediction of flow discharge, and in particular floods, in rivers is one of the basic and key information in regards to operation and management of the river systems. The Fitzroy River, one of the...

Impacts of uncontrolled discharge of acid rock drainage from Mount Morgan Minesite on Dee River (2007)

Tarakemeh, N., Zhang, Hong, Yu, Bofu, McCombe, C.

Uncontrolled discharge of Acid Rock Drainage (ARD) from Mount Morgan mine site accumulated over time poses significant environmental risk on the Dee River downstream. This paper investigates and flow...

Summer Upwelling in the Northern Continental Shelf of the South China Sea (2007)

Jing, Zhiyou, Hua, Z. L., Qi, Y. Q., Zhang, Hong

Summer upwelling system in the northern continental shelf of the South China Sea (NCSCS) is investigated with the Pathfinder, Advanced Very High Resolution Radiometer (AVHRR) Sea Surface Temperature...

Parametric study on the Prediction of Wave-induced Liquefaction using an Artificial Neural Network Model (2007)

Zhang, Hong, Jeng, Dong-Sheng, Cha, Deaho Fred, Blumenstein, Michael Myer

The prediction of the wave-induced liquefaction potential is particularly important for coastal engineers involved in the design of marine structures. An artificial neural network (ANN) model is used...

Horizontal Characteristics of Buoyant Plume off the Pearl River Estuary during Summer (2007)

Ou, Suying, Zhang, Hong, Wang, Dong-xiao, He, Jie

Field measurements of salinity from 1978 to 1984 are used to investigate the horizontal structure of the Pearl River buoyant plume during high river discharge. According to the characteristics of...

Horizontal Characteristics of Buoyant Plume off the Pearl River Estuary during Summer (2007)

Ou, Suying, Zhang, Hong, Wang, Dong-xiao, He, Jie

Field measurements of salinity from 1978 to 1984 are used to investigate the horizontal structure of the Pearl River buoyant plume during high river discharge. According to the characteristics of...

Distribution Category: (2007)

Satish Balay, Kris Buschelman, Victor Eijkhout, Dinesh Kaushik, Matt Knepley, Lois Curfman Mcinnes, ...

This manual describes the use of PETSc for the numerical solution of partial differential equations and related problems on high-performance computers. The Portable, Extensible Toolkit for Scientific...

Molecular dynamic simulations of interactions between LDH and NO3− intercalates in aqueous solution (2007)

Wong, Yunyi, Tran, Pierre, Smith, Sean, Zhang, Hong, Xu, Zhi Ping, Lu, Gao Qing

Using the formula of hydrotalcite-like compounds Mg1−xAlx(OH)2(NO3)x·nH2O, we followed the conformational changes for different models varying the ratio of Al3+. This is the first attempt to study...

Application of artificial neural networks in flow discharge prediction for the Fitzroy River, Australia (2007)

Joorabchi, Amirhassan, Zhang, Hong, Blumenstein, Michael Myer

Prediction of flow discharge, and in particular floods, in rivers is one of the basic and key information in regards to operation and management of the river systems. The Fitzroy River, one of the...

Impacts of uncontrolled discharge of acid rock drainage from Mount Morgan Minesite on Dee River (2007)

Tarakemeh, N., Zhang, Hong, Yu, Bofu, McCombe, C.

Uncontrolled discharge of Acid Rock Drainage (ARD) from Mount Morgan mine site accumulated over time poses significant environmental risk on the Dee River downstream. This paper investigates and flow...

Summer Upwelling in the Northern Continental Shelf of the South China Sea (2007)

Jing, Zhiyou, Hua, Z. L., Qi, Y. Q., Zhang, Hong

Summer upwelling system in the northern continental shelf of the South China Sea (NCSCS) is investigated with the Pathfinder, Advanced Very High Resolution Radiometer (AVHRR) Sea Surface Temperature...

Parametric study on the Prediction of Wave-induced Liquefaction using an Artificial Neural Network Model (2007)

Zhang, Hong, Jeng, Dong-Sheng, Cha, Deaho Fred, Blumenstein, Michael Myer

The prediction of the wave-induced liquefaction potential is particularly important for coastal engineers involved in the design of marine structures. An artificial neural network (ANN) model is used...

Horizontal Characteristics of Buoyant Plume off the Pearl River Estuary during Summer (2007)

Ou, Suying, Zhang, Hong, Wang, Dong-xiao, He, Jie

Field measurements of salinity from 1978 to 1984 are used to investigate the horizontal structure of the Pearl River buoyant plume during high river discharge. According to the characteristics of...

Computer Graphics Using Java 2D and 3D / H. Zhang, Y.D. Liang. (2007)

Zhang, Hong, Liang, Y. Daniel

Contenido: 1. Acercamiento a las gráficas por computadora; 2. Gráficas en 2D: fundamentos; 3. Gráficas en 2D: interpretación de detalles; 4. Gráficas en 2D: temas avanzados (opcional); 5....

Structure of a conserved hypothetical protein SA1388 from S. aureusreveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center (2006)

Saikatendu, Kumar, Zhang, Xuejun, Kinch, Lisa, Leybourne, Matthew, Grishin, Nick V, Zhang, Hong

Abstract Background The protein encoded by the SA1388 gene from Staphylococcus aureus was chosen for structure determination to elucidate its domain organization and confirm our earlier remote...

Characterization of HIV-1 subtype C envelope glycoproteins from perinatally infected children with different courses of disease (2006)

Zhang, Hong, Hoffmann, Federico, He, Jun, He, Xiang, Kankasa, Chipepo, West, John T, ...

Abstract Background The causal mechanisms of differential disease progression in HIV-1 infected children remain poorly defined, and much of the accumulated knowledge comes from studies of subtype B...

Clinicopathological significance of stromal variables: angiogenesis, lymphangiogenesis, inflammatory infiltration, MMP and PINCH in colorectal carcinomas (2006)

Sun, Xiao-Feng, Zhang, Hong

Abstract Cancer research has mainly focused on alterations of genes and proteins in cancer cells themselves that result in either gain-of-function in oncogenes or loss-of-function in...

Molecularly Cloned SHIV-1157ipd3N4: a Highly Replication- Competent, Mucosally Transmissible R5 Simian-Human Immunodeficiency Virus Encoding HIV Clade C env (2006)

Song, R. J., Rasmussen, R. A., Ruprecht, C. R., Mirshahidi, S., Grisson, D. R., ...

Human immunodeficiency virus type 1 (HIV-1) clade C causes >50% of all HIV infections worldwide, and an estimated 90% of all transmissions occur mucosally with R5 strains. A pathogenic R5...

Regulation of glial cell development and axonal outgrowth in the vertebrate central nervous system. (2006)

Zhang, Hong

The complex and diverse functions of the mature vertebrate central nervous system (CNS) depend on the precise interactions formed by many types of neural cells, including neurons and glial cells. The...

Regulation of glial cell development and axonal outgrowth in the vertebrate central nervous system. (2006)

Zhang, Hong

The complex and diverse functions of the mature vertebrate central nervous system (CNS) depend on the precise interactions formed by many types of neural cells, including neurons and glial cells. The...

Service utilization in community health centers in China: a comparison analysis with local hospitals (2006)

Pan, Xilong, Dib, Hassan H, Wang, Xiaohang, Zhang, Hong

Abstract Background Being an important part of China's Urban Health Care Reform System, Community Health Centers (CHCs) have been established throughout the entire country and are presently...

Lattice complexity and fine graining of symbolic sequence (2006)

Ke, Da-Guan, Zhang, Hong, Tong, Qin-Ye

A new complexity measure named as Lattice Complexity is presented for finite symbolic sequences. This measure is based on the symbolic dynamics of one-dimensional iterative maps and Lempel-Ziv...

Efficient and Repetitive Production of Hematopoietic and Endothelial Cells from Feeder-Free Monolayer Culture System of Primate Embryonic Stem Cells1 (2006)

Hong Zhang, Kumiko Saeki, Akiko Kimura, Koichi Saeki, Masako Nakahara, Masaru Doshi, ...

We have established an innovative culture system for the efficient differentiation of hematopoietic and endothelial cells from primate embryonic stem (ES) cells without feeder cells, embryoid bodies,...

The yeast prion protein Ure2: Structure, function and folding (2006)

Lian, Hui-Yong, Jiang, Yi, Zhang, Hong, Jones, Gary, Perrett, Sarah

The Saccharomyces cerevisiae protein Ure2 functions as a regulator of nitrogen metabolism and as a glutathione-dependent peroxidase. Ure2 also has the characteristics of a prion, in that it can...

Characterization of HIV-1 subtype C envelope glycoproteins from perinatally infected children with different courses of disease (2006)

Zhang, Hong, Hoffmann, Federico, He, Jun, He, Xiang, Kankasa, Chipepo, West, John T., ...

Background: The causal mechanisms of differential disease progression in HIV-1 infected children remain poorly defined, and much of the accumulated knowledge comes from studies of subtype B infected...

Periodic solutions for a kind of rayleigh equation with two deviating arguments (2006)

Yuanheng Wu, Bing Xiao, Hong Zhang

In this paper, we use the coincidence degree theory to establish new results on the existence of $T$-periodic solutions for the Rayleigh equation with two deviating arguments of the form $$...

A Scalable Parallel Algorithm for Multiple Objective Linear Programs (2006)

Wiecek, Malgorzata M., Zhang, Hong

This paper presents an ADBASE-based parallel algorithms for solving multiple objective linear programs (MOLPs). Job balance, speedup and scalability are of primary interest in evaluating efficiency...

A Note on Windowing for the Waveform Relaxation (2006)

Zhang, Hong

The technique of windowing has been often used in the implementation of the waveform relaxations for solving ODEs or time dependent PDEs. Its efficiency depends upon problem stiffness and operator...

HO2 Ro-vibrational bound-state calculations for large angular momentum: J=30, 40, and 50 (2006)

Zhang, Hong, Smith, Sean C.

The Lanczos homogeneous filter diagonalization method and the real Chebyshev filter diagonalization scheme incorporating doubling of the autocorrelation functions have been employed to compute the...

HOCl ro-vibrational bound-state calculations for nonzero total angular momentum (2006)

Zhang, Hong, Smith, Sean C., Nanbu, Shinkoh, Nakamura, Hiroki

The Lanczos homogeneous filter diagonalization method has been employed to compute the HOC] ro-vibrational states for a range of total angular momenta (J = 0, 1, 5, 10, 11, 20, 30) on a newly...

The yeast prion protein Ure2: Structure, function and folding (2006)

Lian, Hui-Yong, Jiang, Yi, Zhang, Hong, Jones, Gary, Perrett, Sarah

The Saccharomyces cerevisiae protein Ure2 functions as a regulator of nitrogen metabolism and as a glutathione-dependent peroxidase. Ure2 also has the characteristics of a prion, in that it can...

HO2 Ro-vibrational bound-state calculations for large angular momentum: J=30, 40, and 50 (2006)

Zhang, Hong, Smith, Sean C.

The Lanczos homogeneous filter diagonalization method and the real Chebyshev filter diagonalization scheme incorporating doubling of the autocorrelation functions have been employed to compute the...

HOCl ro-vibrational bound-state calculations for nonzero total angular momentum (2006)

Zhang, Hong, Smith, Sean C., Nanbu, Shinkoh, Nakamura, Hiroki

The Lanczos homogeneous filter diagonalization method has been employed to compute the HOC] ro-vibrational states for a range of total angular momenta (J = 0, 1, 5, 10, 11, 20, 30) on a newly...

Towards Integrated Verification of Timed Transition Models (2006)

Mark Lawford, Vera Pantelic, Hong Zhang

Abstract. This paper describes an attempt to combine theorem proving and model-checking to formally verify real-time systems in a discrete time setting. The Timed Automata Modeling Environment (TAME)...

Improvement of an Artificial Neural Network Model using Min-Max Preprocessing for the Prediction of Wave-induced Seabed Liquefaction (2006)

Cha, Deaho Fred, Blumenstein, Michael Myer, Zhang, Hong, Jeng, D. S.

In the past decade, artificial neural networks (ANNs) have been widely applied to the engineering problems with a complicated system. ANNs are becoming an important alternative option for solving...

Evaluation of Wave-induced Liquefaction in a Porous Seabed: Using an Artificial Neural Network and a Genetic Algorithm -based model (2006)

Cha, Deaho Fred, Jeng, Dong-Sheng, Blumenstein, Michael Myer, Zhang, Hong

The evaluation of wave-induced liquefaction is one of the key factors for analysing seabed characteristics and the design of marine structures. Numerous investigations of wave-induced liquefaction...

The Arabidopsis ascorbate peroxidase 3 is a peroxisomal membrane-bound antioxidant enzyme and is dispensable for Arabidopsis growth and development (2006)

Narendra, Savitha, Venkataramani, Sujatha, Shen, Guoxin, Wang, Jing, Pasapula, Vijaya, Lin, Yun, ...

Ascorbate peroxidase (APX) exists as several isoforms that are found in various compartments in plant cells. The cytosolic and chloroplast APXs appear to play important roles in antioxidation...

Mitochondrial Thioredoxin-2 Has a Key Role in Determining Tumor Necrosis Factor-{alpha}-Induced Reactive Oxygen Species Generation, NF-{kappa}B Activation, and Apoptosis (2006)

Hansen, Jason M., Zhang, Hong, Jones, Dean P.

Tumor necrosis factor-α (TNF-α) is a cytokine that is involved in numerous pathologies, in part through stimulation of the mitochondrial production of reactive oxygen species (ROS). Previous...

Mitochondrial Thioredoxin-2 has a Key Role in Determining Tumor Necrosis Factor-{alpha}-Induced ROS Generation, NF-{kappa}B Activation and Apoptosis (2006)

Hansen, Jason M., Zhang, Hong, Jones, Dean P.

Tumor necrosis factor-α (TNFα) is a cytokine that is involved in numerous pathologies, in part through stimulation of mitochondrial production of reactive oxygen species (ROS). Previous studies...

The Arabidopsis ascorbate peroxidase 3 is a peroxisomal membrane-bound antioxidant enzyme and is dispensable for Arabidopsis growth and development (2006)

Narendra, Savitha, Venkataramani, Sujatha, Shen, Guoxin, Wang, Jing, Pasapula, Vijaya, Lin, Yun, ...

Ascorbate peroxidase (APX) exists as several isoforms that are found in various compartments in plant cells. The cytosolic and chloroplast APXs appear to play important roles in antioxidation...

The Arabidopsis ascorbate peroxidase 3 is a peroxisomal membrane-bound antioxidant enzyme and is dispensable for Arabidopsis growth and development (2006)

Narendra, Savitha, Venkataramani, Sujatha, Shen, Guoxin, Wang, Jing, Pasapula, Vijaya, Lin, Yun, ...

Ascorbate peroxidase (APX) exists as several isoforms that are found in various compartments in plant cells. The cytosolic and chloroplast APXs appear to play important roles in antioxidation...

Evolution of subtype C HIV-1 Env in a slowly progressing Zambian infant (2005)

Zhang, Hong, Hoffmann, Federico, He, Jun, He, Xiang, Kankasa, Chipepo, Ruprecht, Ruth, ...

Abstract Background Given the high prevalence of mother to child infection, the development of a better understanding of African subtype C HIV-1 transmission and natural evolution is of significant...

Spam1-associated transmission ratio distortion in mice: Elucidating the mechanism (2005)

Martin-DeLeon, Patricia A, Zhang, Hong, Morales, Carlos R, Zhao, Yutong, Rulon, Michelle, Barnoski, Barry L, ...

Abstract Background While transmission ratio distortion, TRD, (a deviation from Mendelian ratio) is extensive in humans and well-documented in mice, the underlying mechanisms are unknown. Our earlier...

A comprehensive update of the sequence and structure classification of kinases (2005)

Cheek, Sara, Ginalski, Krzysztof, Zhang, Hong, Grishin, Nick V

Abstract Background A comprehensive update of the classification of all available kinases was carried out. This survey presents a complete global picture of this large functional class of proteins...

Evolution of subtype C HIV-1 Env in a slowly progressing Zambian infant (2005)

Zhang, Hong, Hoffmann, Federico, He, Jun, He, Xiang, Kankasa, Chipepo, Ruprecht, Ruth, ...

Background: Given the high prevalence of mother to child infection, the development of a better understanding of African subtype C HIV-1 transmission and natural evolution is of significant...

A Student On-line Self-Learning Model for Undergraduate Coastal Engineering Courses (2005)

Jeng, D. S., Zhang, Hong

Coastal engineering courses are multi-disciplinary and complex.It is important to develop a self-learning environment forundergraduate students to grasp basic principles and relate themto...

Numerical modeling for breaking wave-induced momentary liquefaction in a porous seabed: Case study at Gold Coast (2005)

Zhang, Hong, Jeng, D. S., Liang Cheng And Kervin Yeow

ABSTRACT: The The evaluation of the wave-induced liquefaction potential is an important issue that must be considered in the design of foundation around coastal structures. Most previous studies have...

An integrated three-dimensional model for wave-induced seabed response in a porous seabed. I. A sloping seabed (2005)

Zhang, Hong, Jeng, D. S.

In this paper, an integrated model for the wave-induced seabed response in a porous seabed is proposed. Most previous studies have considered two-dimensional cases and a flat seabed. In this study, a...

An integrated three-dimensional model of wave-induced pore pressure and effective stresses in a porous seabed: II. Breaking waves (2005)

Jeng, D. S., Zhang, Hong

The evaluation of the wave-induced liquefaction potential is particularly important for coastal engineers involved in the design of marine structures. Most previous investigations of the wave-induced...

A Student On-line Self-Learning Model for Undergraduate Coastal Engineering Courses (2005)

Jeng, D. S., Zhang, Hong

Coastal engineering courses are multi-disciplinary and complex. It is important to develop a self-learning environment for undergraduate students to grasp basic principles and relate them to...

Numerical modeling for breaking wave-induced momentary liquefaction in a porous seabed: Case study at Gold Coast (2005)

Zhang, Hong, Jeng, D. S.

ABSTRACT: The The evaluation of the wave-induced liquefaction potential is an important issue that must be considered in the design of foundation around coastal structures. Most previous studies have...

An integrated three-dimensional model for wave-induced seabed response in a porous seabed. I. A sloping seabed (2005)

Zhang, Hong, Jeng, D. S.

In this paper, an integrated model for the wave-induced seabed response in a porous seabed is proposed. Most previous studies have considered two-dimensional cases and a flat seabed. In this study, a...

An integrated three-dimensional model of wave-induced pore pressure and effective stresses in a porous seabed: II. Breaking waves (2005)

Jeng, D. S., Zhang, Hong

The evaluation of the wave-induced liquefaction potential is particularly important for coastal engineers involved in the design of marine structures. Most previous investigations of the wave-induced...

A Student On-line Self-Learning Model for Undergraduate Coastal Engineering Courses (2005)

Jeng, D. S., Zhang, Hong

Coastal engineering courses are multi-disciplinary and complex. It is important to develop a self-learning environment for undergraduate students to grasp basic principles and relate them to...

Numerical modeling for breaking wave-induced momentary liquefaction in a porous seabed: Case study at Gold Coast (2005)

Zhang, Hong, Jeng, D. S.

ABSTRACT: The The evaluation of the wave-induced liquefaction potential is an important issue that must be considered in the design of foundation around coastal structures. Most previous studies have...

An integrated three-dimensional model for wave-induced seabed response in a porous seabed. I. A sloping seabed (2005)

Zhang, Hong, Jeng, D. S.

In this paper, an integrated model for the wave-induced seabed response in a porous seabed is proposed. Most previous studies have considered two-dimensional cases and a flat seabed. In this study, a...

An integrated three-dimensional model of wave-induced pore pressure and effective stresses in a porous seabed: II. Breaking waves (2005)

Jeng, D. S., Zhang, Hong

The evaluation of the wave-induced liquefaction potential is particularly important for coastal engineers involved in the design of marine structures. Most previous investigations of the wave-induced...

Catalog No. (2005)

Chester Wilmot, Hong Zhang, Haoqiang Fu, Brian Wolshon, Helmut Schneider, Xiaoduan Sun

sponsored by the Louisiana Department of Transportation and Development. The objective of Phase I was to provide a comprehensive review of the state of the art in highway traffic safety, both within...

Microembolic Signal Characterization Using Adaptive Chirplet Expansion (2005)

Yu Zhang, Hong Zhang, Nanxiong Zhang

The adaptive chirplet expansion (ACE) is proposed to characterize high intensity transient signals from circulating microemboli. The non-negative adaptive spectrogram based on the ACE gives a compact...

Doppler Ultrasound Spectral Enhancement Using The Gabor Transform Based Spectral Subtraction (2005)

Yu Zhang, Hong Zhang

Most of the important clinical indices of blood flow are estimated from the spectrograms of Doppler ultrasound (US) signals. Any noise may degrade the readability of the spectrogram and the precision...

Spam1-associated transmission ratio distortion in mice: Elucidating the mechanism (2005)

Martin-DeLeon, Patricia, Zhang, Hong, Morales, Carlos, Zhao, Yutong, Rulon, Michelle, Barnoski, Barry, ...

BACKGROUND:While transmission ratio distortion, TRD, (a deviation from Mendelian ratio) is extensive in humans and well-documented in mice, the underlying mechanisms are unknown. Our earlier studies...

A Student On-line Self-Learning Model for Undergraduate Coastal Engineering Courses (2005)

Jeng, D. S., Zhang, Hong

Coastal engineering courses are multi-disciplinary and complex. It is important to develop a self-learning environment for undergraduate students to grasp basic principles and relate them to...

Numerical modeling for breaking wave-induced momentary liquefaction in a porous seabed: Case study at Gold Coast (2005)

Zhang, Hong, Jeng, D. S.

ABSTRACT: The The evaluation of the wave-induced liquefaction potential is an important issue that must be considered in the design of foundation around coastal structures. Most previous studies have...

An integrated three-dimensional model for wave-induced seabed response in a porous seabed. I. A sloping seabed (2005)

Zhang, Hong, Jeng, D. S.

In this paper, an integrated model for the wave-induced seabed response in a porous seabed is proposed. Most previous studies have considered two-dimensional cases and a flat seabed. In this study, a...

An integrated three-dimensional model of wave-induced pore pressure and effective stresses in a porous seabed: II. Breaking waves (2005)

Jeng, D. S., Zhang, Hong

The evaluation of the wave-induced liquefaction potential is particularly important for coastal engineers involved in the design of marine structures. Most previous investigations of the wave-induced...

EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology (2005)

Reche, Pedro A, Zhang, Hong, Glutting, John-Paul, Reinherz, Ellis L

SUMMARY: EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various...

Prediction of methylated CpGs in DNA sequences using a support vector machine (2005)

Bhasin, Manoj, Zhang, Hong, Reinherz, Ellis L, Reche, Pedro A

DNA methylation plays a key role in the regulation of gene expression. The most common type of DNA modification consists of the methylation of cytosine in the CpG dinucleotide. At the present time,...

Long-lived Charge-Transfer States in 9-Aryl-Acridinium Ions; A Critical Reinvestigation (2005)

Jan W. Verhoeven, Hong Zhang, Michiel M. Groeneveld, Andrew C. Benniston, Anthony Harriman

In the recent literature a simple 9-aryl-acridinium ion was claimed to undergo an intramolecular, photoinduced charge shift to produce an extremely long-lived and very high energy charge-transfer...

In vitro resistance to the CS{alpha}{beta}-type antimicrobial peptide ASABF- is conferred by overexpression of sigma factor sigB in Staphylococcus aureus (2005)

Zhang, Hong, Morikawa, Kazuya, Ohta, Toshiko, Kato, Yusuke

Objectives: ASABF (Ascaris suum antibacterial factor) is a CSαβ-type antimicrobial peptide isolated from nematodes. ASABF-α, a member of ASABF, is particularly effective against the Gram-positive...

Expression of An Arabidopsis Vacuolar Sodium/Proton Antiporter Gene in Cotton Improves Photosynthetic Performance under Salt Conditions and Increases Fiber Yield in the Field (2005)

He, Cixin, Yan, Juqiang, Shen, Guoxin, Fu, Lianhai, Holaday, A. Scott, Auld, Dick, ...

Drought and salinity are two major limiting factors in crop productivity. One way to reduce crop loss caused by drought and salinity is to increase the solute concentration in the vacuoles of plant...

Expression of an Arabidopsis Vacuolar Sodium/Proton Antiporter Gene in Cotton Improves Photosynthetic Performance Under Salt Conditions and Increases Fiber Yield in the Field (2005)

He, Cixin, Yan, Juqiang, Shen, Guoxin, Fu, Lianhai, Holaday, A. Scott, Auld, Dick, ...

Drought and salinity are two major limiting factors in crop productivity. One way to reduce crop loss caused by drought and salinity is to increase the solute concentration in the vacuoles of plant...

In vitro resistance to the CS{alpha}{beta}-type antimicrobial peptide ASABF- is conferred by overexpression of sigma factor sigB in Staphylococcus aureus (2005)

Zhang, Hong, Morikawa, Kazuya, Ohta, Toshiko, Kato, Yusuke

Objectives: ASABF (Ascaris suum antibacterial factor) is a CSαβ-type antimicrobial peptide isolated from nematodes. ASABF-, a member of ASABF, is particularly effective against the Gram-positive...

EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology (2005)

Reche, Pedro A., Zhang, Hong, Glutting, John-Paul, Reinherz, Ellis L.

Summary: EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various...

EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology (2005)

Reche, Pedro A., Zhang, Hong, Glutting, John-Paul, Reinherz, Ellis L.

Summary: EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently the database contains 4867 distinct peptide sequences from various...

Expression of An Arabidopsis Vacuolar Sodium/Proton Antiporter Gene in Cotton Improves Photosynthetic Performance under Salt Conditions and Increases Fiber Yield in the Field (2005)

He, Cixin, Yan, Juqiang, Shen, Guoxin, Fu, Lianhai, Holaday, A. Scott, Auld, Dick, ...

Drought and salinity are two major limiting factors in crop productivity. One way to reduce crop loss caused by drought and salinity is to increase the solute concentration in the vacuoles of plant...

Spam1 (PH-20) Expression in the Extratesticular Duct and Accessory Organs of the Mouse: A Possible Role in Sperm Fluid Reabsorption1 (2004)

Hong Zhang, Carlos R. Morales, Haitham Badran, Mohamed El-Alfy

A widely conserved sperm antigen, the sperm adhesion molecule 1 (SPAM1 or PH-20) is a glycosylphosphatidyl inositol-linked protein with multiple roles in mammalian fertilization. It has been shown to...

Recent developments in the quantum dynamical characterization of unimolecular resonances (2004)

Hong Zhang, Sean Smith

This invited review article summarized original developments in theory and computational methodologies for quantum resonances, incorporating developments by myself, Zhang, and previous members of my...

Hydrodynamic model with wave-current interaction in coastal regions (2004)

Zhang, Hong, Madsen, Ole S., Sannasiraj, S.A., Chan, Eng Soon

The effects of wave current interaction on the hydrodynamics in coastal regions are investigated. A modified Grant Madsen analytical model is incorporated into the Princeton Ocean Model (POM) to...

Enhancing tidal prediction accuracy in a deterministic model using chaos theory (2004)

Sannasiraj, S.A., Zhang, Hong, Babovic, Vladan, Chan, Eng Soon

The classical deterministic approach to tidal prediction is based on barotropic or baroclinic models with prescribed boundary conditions from a global model or measurements. The prediction by the...

Hydrodynamic model with wave-current interaction in coastal regions (2004)

Zhang, Hong, Madsen, Ole S., Sannasiraj, S.A., Chan, Eng Soon

The effects of wave current interaction on the hydrodynamics in coastal regions are investigated. A modified Grant Madsen analytical model is incorporated into the Princeton Ocean Model (POM) to...

Enhancing tidal prediction accuracy in a deterministic model using chaos theory (2004)

Sannasiraj, S.A., Zhang, Hong, Babovic, Vladan, Chan, Eng Soon

The classical deterministic approach to tidal prediction is based on barotropic or baroclinic models with prescribed boundary conditions from a global model or measurements. The prediction by the...

Hydrodynamic model with wave-current interaction in coastal regions (2004)

Zhang, Hong, Madsen, Ole S., Sannasiraj, S.A., Chan, Eng Soon

The effects of wave current interaction on the hydrodynamics in coastal regions are investigated. A modified Grant Madsen analytical model is incorporated into the Princeton Ocean Model (POM) to...

Enhancing tidal prediction accuracy in a deterministic model using chaos theory (2004)

Sannasiraj, S.A., Zhang, Hong, Babovic, Vladan, Chan, Eng Soon

The classical deterministic approach to tidal prediction is based on barotropic or baroclinic models with prescribed boundary conditions from a global model or measurements. The prediction by the...

Recent developments in the quantum dynamical characterization of unimolecular resonances (2004)

Zhang, Hong, Smith, Sean C.

We give a selective review of quantum mechanical methods for calculating and characterizing resonances in small molecular systems, with an emphasis on recent progress in Chebyshev and Lanczos...

Diacylglycerols from butterfat: production by Glycerolysis and short-path diltillation and analysis of physical properties (2004)

Yang, Tiankui, Zhang, Hong, Mu, Huiling, Sinclair, Andrew, Xu, Xuebing

The aim of this paper was to develop a process for the production of DAG from butterfat through glycerolysis and short-path distillation and to evaluate the physical properties of the DAG in...

Recent developments in the quantum dynamical characterization of unimolecular resonances (2004)

Zhang, Hong, Smith, Sean C.

We give a selective review of quantum mechanical methods for calculating and characterizing resonances in small molecular systems, with an emphasis on recent progress in Chebyshev and Lanczos...

The GRITIKA ontology for modeling e-service applications: Formal specification and illustration (2004)

Hong Zhang, Rajiv Kishore, Raj Sharman, Ram Ramesh

In this paper we develop and discuss a special-purpose computational ontology (similar to the notion of conceptual grammar) termed GRITIKA (acronym for

Hydrodynamic model with wave-current interaction in coastal regions (2004)

Zhang, Hong, Madsen, Ole S., Sannasiraj, S.A., Chan, Eng Soon

The effects of wave–current interaction on the hydrodynamics in coastal regions are investigated. A modified Grant–Madsen analytical model is incorporated into the Princeton Ocean Model (POM) to...

Enhancing tidal prediction accuracy in a deterministic model using chaos theory (2004)

Sannasiraj, S.A., Zhang, Hong, Babovic, Vladan, Chan, Eng Soon

The classical deterministic approach to tidal prediction is based on barotropic or baroclinic models with prescribed boundary conditions from a global model or measurements. The prediction by the...

Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles (2004)

Reche, Pedro A, Glutting, John-Paul, Zhang, Hong, Reinherz, Ellis L

We introduced previously an on-line resource, RANKPEP that uses position specific scoring matrices (PSSMs) or profiles for the prediction of peptide-MHC class I (MHCI) binding as a basis for CD8...

Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-tack and vascular endothelial growth factor receptor type 2 (2004)

Toyofuku, Toshihiko, Zhang, Hong, Kumanogoh, Atsushi, Takegahara, Noriko, Suto, Fumikazu, Kamei, Junko, ...

Semaphorins, originally identified as axon guidance factors in the nervous system, play integral roles in organogenesis. Here, we demonstrate a critical involvement of Sema6D in cardiac...

Smurf2 up-regulation activates telomere-dependent senescence (2004)

Zhang, Hong, Cohen, Stanley N.

Progressive telomere shortening activates replicative senescence, which prevents somatic cells from being propagated indefinitely in culture. The limitation of proliferative capacity imposed by...

Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2 (2004)

Toyofuku, Toshihiko, Zhang, Hong, Kumanogoh, Atsushi, Takegahara, Noriko, Suto, Fumikazu, Kamei, Junko, ...

Semaphorins, originally identified as axon guidance factors in the nervous system, play integral roles in organogenesis. Here, we demonstrate a critical involvement of Sema6D in cardiac...

Smurf2 up-regulation activates telomere-dependent senescence (2004)

Zhang, Hong, Cohen, Stanley N.

Progressive telomere shortening activates replicative senescence, which prevents somatic cells from being propagated indefinitely in culture. The limitation of proliferative capacity imposed by...

Overexpression of the Arabidopsis 14-3-3 Protein GF14{lambda} in Cotton Leads to a "Stay-Green" Phenotype and Improves Stress Tolerance under Moderate Drought Conditions (2004)

Yan, Juqiang, He, Cixin, Wang, Jing, Mao, Zhehui, Holaday, Scott A., Allen, Randy D., ...

The Arabidopsis gene GF14&lgr; that encodes a 14-3-3 protein was introduced into cotton plants to explore the physiological roles that GF14&lgr; might play in plants. The expression level of...

Diacylglycerols from butterfat: production by Glycerolysis and short-path diltillation and analysis of physical properties (2004)

Yang, Tiankui, Zhang, Hong, Mu, Huiling, Sinclair, Andrew, Xu, Xuebing

The aim of this paper was to develop a process for the production of DAG from butterfat through glycerolysis and short-path distillation and to evaluate the physical properties of the DAG in...

Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-tack and vascular endothelial growth factor receptor type 2 (2004)

Toyofuku, Toshihiko, Zhang, Hong, Kumanogoh, Atsushi, Takegahara, Noriko, Suto, Fumikazu, Kamei, Junko, ...

Semaphorins, originally identified as axon guidance factors in the nervous system, play integral roles in organogenesis. Here, we demonstrate a critical involvement of Sema6D in cardiac...

Smurf2 up-regulation activates telomere-dependent senescence (2004)

Zhang, Hong, Cohen, Stanley N.

Progressive telomere shortening activates replicative senescence, which prevents somatic cells from being propagated indefinitely in culture. The limitation of proliferative capacity imposed by...

SPAM1 (PH-20) protein and mRNA expression in the epididymides of humans and macaques: utilizing laser microdissection/RT-PCR (2003)

Evans, Eric A, Zhang, Hong, Martin-DeLeon, Patricia A

Abstract Background The Sperm Adhesion Molecule 1 (SPAM1) is an important sperm surface hyaluronidase with at least three functions in mammalian fertilization. Previously our laboratory reported that...

Mouse Spam1 (PH-20) Is a Multifunctional Protein: Evidence for Its Expression in the Female Reproductive Tract1 (2003)

Hong Zhang

Sperm adhesion molecule 1 (Spam1) is a widely conserved sperm surface protein with multiple roles in mammalian fertilization. Although the gene for this protein has been thought to be testis specific...

Turbulence control by developing a spiral wave with a periodic signal injection in the complex Ginzburg-Landau equation (2003)

Zhang, Hong, Hu, Bambi, Hu, Gang, Ouyang, Qi, Kurths, J.

Turbulence control in the two-dimensional complex Ginzburg-Landau equation is investigated. A new approach is proposed for the control purpose. In the presence of a small spiral wave seed initiation,...

Active queue management of multimedia flows over ATM networks / (2003)

Zhang, Hong.

Thesis (M. Sc. (Comm. Software & Networks))--Nanyang Technological University, School of Electrical and Electronic Engineering, 2003.

Calculation of bound and resonance states of HO2 for nonzero total angular momentum (2003)

Zhang, Hong, Smith, Sean C.

Bound and resonance states of HO2 have been calculated quantum mechanically by the Lanczos homogeneous filter diagonalization method [Zhang and Smith, Phys. Chem. Chem. Phys. 3, 2282 (2001); J. Chem....

A comparative study of iterative Chebyshev and Lanczos implementations of the boundary inhomogeneity method for quantum scattering (2003)

Zhang, Hong, Smith, Sean C.

We have recently developed a scaleable Artificial Boundary Inhomogeneity (ABI) method [Chem. Phys. Lett.366, 390–397 (2002)] based on the utilization of the Lanczos algorithm, and in this work...

Photosynthesis and seed production under water-deficit conditions in transgenic tobacco plants that over-express an Arabidopsis ascorbate peroxidase gene (2003)

Yan, Juqiang, Wang, Jing, Tissue, David T., Holaday, A.Scott, Allen, Randy, Zhang, Hong

An underlying mechanism for reductions in crop yield under stress conditions is excessive production of reactive oxygen species (ROS) that can damage lipids, nucleic acids, and proteins, leading to...

Calculation of bound and resonance states of HO2 for nonzero total angular momentum (2003)

Zhang, Hong, Smith, Sean C.

Bound and resonance states of HO2 have been calculated quantum mechanically by the Lanczos homogeneous filter diagonalization method [Zhang and Smith, Phys. Chem. Chem. Phys. 3, 2282 (2001); J. Chem....

A comparative study of iterative Chebyshev and Lanczos implementations of the boundary inhomogeneity method for quantum scattering (2003)

Zhang, Hong, Smith, Sean C.

We have recently developed a scaleable Artificial Boundary Inhomogeneity (ABI) method [Chem. Phys. Lett.366, 390–397 (2002)] based on the utilization of the Lanczos algorithm, and in this work...

discovery of working activities by email analysis (2003)

Yueyu Fu, Hong Zhang

Email has become one of the most widely used computer applications. As the number of emails we exchange increases at high rate, the number of uses for email increases. Email data patterns may give us...

A diffusive transport mechanism for fine sediments (2003)

Madsen, Ole Secher, Pahuja, Sanjay, Zhang, Hong, Chan, Eng Soon

A simple conceptual model (SCM) for the net transport of suspended sediments associated with a simple harmonic tidal current superimposed on a spatially varying, wind-wave-induced near-bottom...

A diffusive transport mechanism for fine sediments (2003)

Madsen, Ole Secher, Pahuja, Sanjay, Zhang, Hong, Chan, Eng Soon

A simple conceptual model (SCM) for the net transport of suspended sediments associated with a simple harmonic tidal current superimposed on a spatially varying, wind-wave-induced near-bottom...

Ultrasonic vibration assisted Electro-discharge machining of microholes in Nitinol (2003)

Huang, H, Zhang, Hong, Zhou, L, Zheng, H Y

An ultrasonic vibration has been superposed on the normal electrode movement to increase the flushing effect during a micro electro-discharge machining (EDM) process. A systematic study on the...

Ultrasonic vibration assisted Electro-discharge machining of microholes in Nitinol (2003)

Huang, H, Zhang, Hong, Zhou, L, Zheng, H Y

An ultrasonic vibration has been superposed on the normal electrode movement to increase the flushing effect during a micro electro-discharge machining (EDM) process. A systematic study on the...

Modeling of the turbulence in the water column under breaking wind waves (2003)

Zhang, Hong, Chan, Eng-Soon

Past studies have shown that there is a wave-enhanced, near-surface mixed-layer in which the dissipation rate is greater than that derived from the “law of the wall”. In this study, turbulence in...

A diffusive transport mechanism for fine sediments (2003)

Madsen, Ole Secher, Pahuja, Sanjay, Zhang, Hong, Chan, Eng Soon

A simple conceptual model (SCM) for the net transport of suspended sediments associated with a simple harmonic tidal current superimposed on a spatially varying, wind-wave-induced near-bottom...

Ultrasonic vibration assisted Electro-discharge machining of microholes in Nitinol (2003)

Huang, H, Zhang, Hong, Zhou, L, Zheng, H Y

An ultrasonic vibration has been superposed on the normal electrode movement to increase the flushing effect during a micro electro-discharge machining (EDM) process. A systematic study on the...

Photosynthesis and seed production under water-deficit conditions in transgenic tobacco plants that over-express an Arabidopsis ascorbate peroxidase gene (2003)

Yan, Juqiang, Wang, Jing, Tissue, David T., Holaday, A. Scott, Allen, Randy, Zhang, Hong

An underlying mechanism for reductions in crop yield under stress conditions is excessive production of reactive oxygen species (ROS) that can damage lipids, nucleic acids, and proteins, leading to...

Ultraviolet A and B differently induce intracellular protein expression in human skin melanocytes - a speculation of separate pathways in initiation of melanoma (2003)

Zhang, Hong, Rosdahl, Inger

Ultraviolet (UV) irradiation has been involved in both initiation and promotion of carcinogenesis in melanoma. Alterations of cellular proliferation-proteins, such as p73, Nup88, Id1 and p27 have...

Ultraviolet A and B differently induce intracellular protein expression in human skin melanocytes--a speculation of separate pathways in initiation of melanoma (2003)

Zhang, Hong, Rosdahl, Inger

Ultraviolet (UV) irradiation has been involved in both initiation and promotion of carcinogenesis in melanoma. Alterations of cellular proliferation proteins, such as p73, Nup88, Id1 and p27 have...

Ultraviolet A and B differently induce intracellular protein expression in human skin melanocytes - a speculation of separate pathways in initiation of melanoma (2003)

Zhang, Hong, Rosdahl, Inger

Ultraviolet (UV) irradiation has been involved in both initiation and promotion of carcinogenesis in melanoma. Alterations of cellular proliferation-proteins, such as p73, Nup88, Id1 and p27 have...

中国のWTO加盟と西部大開発の政策調整 (2002)

張, 鴻, Zhang, Hong

Development of the West region and China’s entry into WTO are two hot issues in the 21st century. Policies for developing the West region were formulated before China’s entry into WTO, so that...

Granulometry using image transformation techniques (2002)

Hong Zhang, Martin Jägers

In this paper, we present our preliminary study on using transformation-based techniques for performing granulometry analysis. We examine specifically the problem of the particle size analysis in oil...

Modeling of Vertical Thermal Structure Using Genetic Programming (2002)

Babovic, Vladan, Zhang, Hong

The process of scientific discovery has long been viewed as the pinnacle of creative thought. Thus, to many people, including some scientists themselves is seems unlikely candidate for automation by...

Coupled Ocean Circulation and Wind-Wave Models With Data Assimilation Using Altimeter Statistics (2002)

Zhang, Hong, Sannasiraj, S.A., Islam, Md. Monirul, Kek, Choo Heng

Coupled ocean wave and circulation models have been implemented under the IOEPAS program (Integrated Ocean Environment Prediction and Assimilation System). The third generation wave model, WAM and...

Modeling of Vertical Thermal Structure Using Genetic Programming (2002)

Babovic, Vladan, Zhang, Hong

The process of scientific discovery has long been viewed as the pinnacle of creative thought. Thus, to many people, including some scientists themselves is seems unlikely candidate for automation by...

Coupled Ocean Circulation and Wind-Wave Models With Data Assimilation Using Altimeter Statistics (2002)

Zhang, Hong, Sannasiraj, S.A., Islam, Md. Monirul, Kek, Choo Heng

Coupled ocean wave and circulation models have been implemented under the IOEPAS program (Integrated Ocean Environment Prediction and Assimilation System). The third generation wave model, WAM and...

Modeling of Vertical Thermal Structure Using Genetic Programming (2002)

Babovic, Vladan, Zhang, Hong

The process of scientific discovery has long been viewed as the pinnacle of creative thought. Thus, to many people, including some scientists themselves is seems unlikely candidate for automation by...

Coupled Ocean Circulation and Wind-Wave Models With Data Assimilation Using Altimeter Statistics (2002)

Zhang, Hong, Sannasiraj, S.A., Islam, Md. Monirul, Kek, Choo Heng

Coupled ocean wave and circulation models have been implemented under the IOEPAS program (Integrated Ocean Environment Prediction and Assimilation System). The third generation wave model, WAM and...

UV-induced T->C transition at a TT photoproduct site is dependent on Saccharomyces cerevisiae polymerase {eta}in vivo (2002)

Zhang, Hong, Siede, Wolfram

UV-induced reversion of the arg4-17 ochre allele in Saccharomyces cerevisiae is largely dependent on translesion polymerase &eegr; (Rad30p), known to bypass cyclobutane-type TT dimers in an...

Evolution of the Chern-Simons Vortices (2001)

Fu, Li-Bin, Duan, Yi-Shi, Zhang, Hong

Based on the gauge potential decomposition theory and the $\phi $-mapping theory, the topological inner structure of the Chern-Simons-Higgs vortex has been showed in detail. The evolution of CSH...

Topological excitation in the Fractional Quantum Hall system (2001)

Duan, Yi-shi, Zhang, Peng-ming, Zhang, Hong

Two kinds of topological excitations, vortices and skyrmions, are studied in the frame of Ginzburg-Landau theory. We obtain the rigorous relation between the topological excitation and the order...

Kirsten Ras Mutations In Patients With Colorectal Cancer: The 'RASCAL II' Study (2001)

Andreyev, H. Jervoise N., Norman, Andrew R., Cunningham, David, Oates, Jacqueline, Dix, Brett R., Iacopetta, Barry J., ...

Researchers worldwide with information about the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer were invited to provide that data in a schematized format for...

Kirsten Ras Mutations In Patients With Colorectal Cancer: The 'RASCAL II' Study (2001)

Andreyev, H. Jervoise N., Norman, Andrew R., Cunningham, David, Oates, Jacqueline, Dix, Brett R., Iacopetta, Barry J., ...

Researchers worldwide with information about the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer were invited to provide that data in a schematized format for...

Kirsten Ras Mutations In Patients With Colorectal Cancer: The 'RASCAL II' Study (2001)

Andreyev, H. Jervoise N., Norman, Andrew R., Cunningham, David, Oates, Jacqueline, Dix, Brett R., Iacopetta, Barry J., ...

Researchers worldwide with information about the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer were invited to provide that data in a schematized format for...

Kirsten Ras Mutations In Patients With Colorectal Cancer: The 'RASCAL II' Study (2001)

Andreyev, H. Jervoise N., Norman, Andrew R., Cunningham, David, Oates, Jacqueline, Dix, Brett R., Iacopetta, Barry J., ...

Researchers worldwide with information about the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer were invited to provide that data in a schematized format for...

Kirsten Ras Mutations In Patients With Colorectal Cancer: The 'RASCAL II' Study (2001)

Andreyev, H. Jervoise N., Norman, Andrew R., Cunningham, David, Oates, Jacqueline, Dix, Brett R., Iacopetta, Barry J., ...

Researchers worldwide with information about the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer were invited to provide that data in a schematized format for...

Planar Patch Extraction with Noisy Depth Data (2001)

Dana Cobzas, Hong Zhang

This paper presents an algorithm for extracting planar patches by integrating both intensity and range data provided by a stereo system. For dealing with noisy and sparse range data, the initial...

Kirsten Ras Mutations In Patients With Colorectal Cancer: The 'RASCAL II' Study (2001)

Andreyev, H. Jervoise N., Norman, Andrew R., Cunningham, David, Oates, Jacqueline, Dix, Brett R., Iacopetta, Barry J., ...

Researchers worldwide with information about the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer were invited to provide that data in a schematized format for...

Four-dimensional dielectric property image obtained from electron spectroscopic imaging series (2001)

Lo, Shen-Chuan, Kai, Ji-Jung, Chen, Fu-Rong, Chang, Li, Chen, Li-Chien, Chiang, Cheng-Cheng, ...

We have demonstrated a new quantitative method to characterize two‐dimensional distributions of energy‐dependent dielectric function of materials from low loss electron spectroscopic...

Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel(R) under angiogenic conditions (2001)

Schmeisser, Alexander, Garlichs, Christoph D., Zhang, Hong, Eskafi, Saeed, Graffy, Christiane, Ludwig, Josef, ...

Objectives: It has been shown that circulating human non-adherent CD34+ cells coexpressing vascular endothelial growth factor (VEGF)-R2 and AC133 have the capacity to differentiate into adherent...

Bcl2-L-10, a novel anti-apoptotic member of the Bcl-2 family, blocks apoptosis in the mitochondria death pathway but not in the death receptor pathway (2001)

Zhang, Hong, Holzgreve, Wolfgang, De Geyter, Christian

By GenBank database searches and PCR, we have identified a novel human Bcl2-like gene, Bcl2-L-10, which contains conserved BH4, BH1 and BH2 domains but lacks BH3 domain. The Bcl2-L-10 gene has been...

Kirsten Ras Mutations In Patients With Colorectal Cancer: The 'RASCAL II' Study (2001)

Andreyev, H. Jervoise N., Norman, Andrew R., Cunningham, David, Oates, Jacqueline, Dix, Brett R., Iacopetta, Barry J., ...

Researchers worldwide with information about the Kirsten ras (Ki-ras) tumour genotype and outcome of patients with colorectal cancer were invited to provide that data in a schematized format for...

Radiation-Induced DNA Damage in Tumors and Normal Tissues. VI. Estimation of the HypoxicFraction of Experimental Tumors1 (2000)

Vijay K. Kalia, Isaf Al-Nabulsi, C. Anne Wallen, Hong Zhang, Kenneth T. Wheeler

Kalia, V. K., Al-Nabulsi, I., Wallen, C. A., Zhang, H. and Wheeler, K. T. Radiation-Induced DNA Damage in Tumors and Normal Tissues. VI. Estimation of the Hypoxic Fraction of Experimental Tumors. For...

Structural conservations and diversities of dsRNA viruses: Structural studies of the cytoplasmic polyhedrosis virus by electron cryomicroscopy and three dimensional reconstruction (2000)

Zhang, Hong

The Reoviridae virus family is a group of economically and pathologically important viruses that have either single-, double-, or triple-shelled protein layers enclosing a segmented double stranded...

Motion control for dynamic mobile robots (2000)

Zhang, Hong

In this thesis, we present research results on sensor-based motion planning and nonlinear control for mobile robotic systems. In sensor-based motion planning, we use ideas from game theory to deal...

Tetraspanins : role in MHC class II distribution and trafficking / (2000)

Zhang, Hong.

"[S]ubmitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirement for the degree of Master of Science, in Medical Science-Oncology."

Tetraspanins : role in MHC class II distribution and trafficking / (2000)

Zhang, Hong.

"Submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirement for the degree of Master of Science, in Medical Science-Oncology".

2d robot localization with image-based panoramic models using vertical line features (2000)

Dana Cobzas, Hong Zhang

This paper presents a method for estimating the position of a mobile robot in an indoor environment. The proposed technique uses a model of the environment formed by two panoramic cylindrical images...

Automatic generation of 2d canonical grasps (2000)

Yisheng Guan, Hong Zhang

The concepts of canonical grasp and grasp transformation graph proposed in [10] are useful in grasp planning and dextrous manipulation. However, one critical element, namely the automatic generation...

Localizing a Polyhedral Object in a Robot Hand by Integrating Visual and Tactile Data (2000)

Michael Boshra, Hong Zhang

We present a novel technique for localizing a polyhedral object in a robot hand by integrating visual and tactile data. Localization is performed by matching a hybrid set of visual and tactile...

Kinematic Graspability of a 2D Multifingered Hand (2000)

Yisheng Guan And, Yisheng Guan, Hong Zhang

In this paper, we describe a solution to the problem of determining the kinematic feasibility of a dextrous hand to grasp a given object at a desired configuration in the two dimensional space. We...

Pseudozeros Of Multivariate Polynomials (2000)

J. William Hoffman, James J. Madden, HONG ZHANG

. The pseudozero set of a system f of polynomials in n complex variables is the subset of C n which is the union of the zero - sets of all polynomial systems g that are near to f in a suitable sense....

2D Robot Localization with Image-Based Panoramic Models Using Vertical Line Features (2000)

Dana Cobzas, Hong Zhang

This paper presents a method for estimating the position of a mobile robot in an indoor environment. The proposed technique uses a model of the environment formed by two panoramic cylindrical images...

Optimal Motion Planning in the Image Plane for Mobile Robots (2000)

Hong Zhang, Jim Ostrowski

This paper presents a novel approach to image-based visual servoing by making motion plans directly in the image plane. By skipping the step of transferring image features back to robot pose, we are...

Characterization of an immortalized human granulosa cell line (COV434) (2000)

Zhang, Hong, Vollmer, Marielle, De Geyter, Maria, Litzistorf, Yvonne, Ladewig, Ariane, Dürrenberger, Markus, ...

We have investigated the biological characteristics of an immortalized granulosa cell line (COV434), which may be used to study follicular and oocyte maturation in vitro. Granulosa cell function was...

Mismatch repair is required for O6-methylguanine-induced homologous recombination in human fibroblasts (2000)

Zhang, Hong, Marra, Giancarlo, Jiricny, Josef, Maher, Veronica M., McCormick, J.Justin

O6-methylguanine is responsible for homologous recombination induced by N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) [H.Zhang et al. (1996) Carcinogenesis, 17, 2229]. To test the...

Granulometry using mathematical morphology and motion (2000)

Fadi Dornaika, Hong Zhang

This paper describes an efficient framework for image-based granulometry, which provides three main contributions. First, unlike most of the existing work on particle delineation, which is based on...

Topological current of point defects and its bifurcation (1999)

Duan, Yishi, Fu, Libin, Zhang, Hong

From the topological properties of a three dimensional vector order parameter, the topological current of point defects is obtained. One shows that the charge of point defects is determined by Hopf...

Topological quantum mechanics and the first Chern class (1999)

Duan, Yishi, Fu, Libin, Zhang, Hong

Topological properties of quantum system is directly associated with the wave function. Based on the decomposition theory of gauge potential, a new comprehension of topological quantum mechanics is...

Visual Servo with Dynamics: Control of an Unmanned Blimp (1999)

Hong Zhang, James P. Ostrowski

Image-based control of free-flying mechanical systems is addressed, with application to an indoor, vision-guided blimp. A methodology is developed for performing visual servoing by incorporating the...

A Constraint-Satisfaction Approach for 3-D Object Recognition by Integrating 2-D and 3-D Data (1999)

Michael Boshra, Hong Zhang

We present a technique for integrating 2-D and 3-D sensory data in the context of 3-D object recognition. The 3-D object recognition problem can be stated as follows. Given a set of model objects,...

Overexpression of an Arabidopsis Peroxisomal Ascorbate Peroxidase Gene in Tobacco Increases Protection Against Oxidative Stress (1999)

Wang, Jing, Zhang, Hong, Allen, Randy D.

The Arabidopsis gene APX3 that encodes a putative peroxisomal membrane-bound ascorbate peroxidase was expressed in transgenic tobacco plants. APX3-expressing lines had substantial levels of APX3 mRNA...

Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: Role of membrane-bound NADH-/NADPH-oxidases (1999)

Zhang, Hong, Schmeißer, Alexander, Garlichs, Christoph D, Plötze, Katrin, Damme, Uwe, Mügge, Andreas, ...

Background: Angiotensin II (ANG II) mediated hypertension accelerates atherosclerosis (AS) and thereby increases the incidence of myocardial infarction (MI). On the other hand, superoxide anion...

On Waveform Multigrid Method. (1998)

Ta'asan, Shlomo, Zhang, Hong

Waveform multigrid method is an efficient method for solving certain classes of time-dependent PDEs. This paper studies the relationship between this method and the analogous multigrid method for...

Using Parallel Banded Linear System Solvers in Generalized Eigenvalue Problems. (1998)

Zhang, Hong, Moss, William F.

Subspace iteration is a reliable and cost effective method for solving positive definite banded symmetric generalized eigenproblems, especially in the case of large scale problems. This paper...

Dermal Absorption of Modular Artillery Charge (XM231). (1998)

McDougal, James N., Zhang, Hong, Pollard, Daniel L., Jepson, Gary W., Yu, Kyung O.

Soldiers handling modular artillery propellant increments may have the potential to absorb chemical components through the skin of the hands. The purpose of this research was to determine if systemic...

Dermal Absorption of Modular Artillery Charge (XM232). (1998)

McDougal, James N., Zhang, Hong, Pollard, Daniel L., Jepson, Gary W., Yu, Kyung O.

Soldiers handling Howitzer cartridges may have the potential to absorb the components of solid propellants through the skin of the hands. The purpose of this research was to determine if systemic...

A Novel Apoptosis Regulator (1998)

Zhang, Hong

BAR is a multi-domain protein. A screen for cDNAs encoding suppressors of Bax induced cell death was performed in the yeast S. cerevisiae, resulting in a cDNA containing an open reading frame (ORF)...

Digital Breast Imaging Warehouse for Research and Clinical Decision Support (1998)

Zhang, Hong

Breast imaging is used intensively for breast cancer detection. As routine screening examination becomes more popular for women over 40, tremendous amount of breast imaging data has been accumulated....

Influence of Surface and Bottom Stress in the Coupled Ocean Circulation and Wind-Wave Models (1998)

Zhang, Hong, Sannasiraj, S. A., Tark, N. G. Keong

Viewgraphs on presentation of the influence of surface and bottom stress in the coupled ocean circulation and wind-wave models.

BARC: A Novel Apoptosis Regulator (1998)

Jin, Can, Zhang, Hong, Chae, Han J., Reed, John C.

Breast cancers arise due to an imbalance in cell production relative to cell turnover, resulting in a net accumulation of abnormal cells. Cell turnover is normally achieved through programmed cell...

BARC: A Novel Apoptosis Regulator (1998)

Jin, Can, Reed, John C., Zhang, Hong, Chae, Han J.

Breast cancers arise due to an imbalance in cell production relative to cell turnover, resulting in a net accumulation of abnormal cells. Cell turnover is normally achieved in the body by a process...

Identification and characterization of the 5'-flanking region of the rat galanin gene (1998)

Zhang, Hong

Galanin, a neuropeptide widely distributed throughout the central and eripheral nervous systems, is a biologically active peptide which is strongly upregulated by nerve injury, estrogen and during...

Identification and characterization of the 5'-flanking region of the rat galanin gene (1998)

Zhang, Hong

Galanin, a neuropeptide widely distributed throughout the central and eripheral nervous systems, is a biologically active peptide which is strongly upregulated by nerve injury, estrogen and during...

Identification and characterization of the 5'-flanking region of the rat galanin gene (1998)

Zhang, Hong

Galanin, a neuropeptide widely distributed throughout the central and eripheral nervous systems, is a biologically active peptide which is strongly upregulated by nerve injury, estrogen and during...

Identification and characterization of the 5'-flanking region of the rat galanin gene (1998)

Zhang, Hong

Galanin, a neuropeptide widely distributed throughout the central and eripheral nervous systems, is a biologically active peptide which is strongly upregulated by nerve injury, estrogen and during...

Identification and characterization of the 5'-flanking region of the rat galanin gene (1998)

Zhang, Hong

Galanin, a neuropeptide widely distributed throughout the central and eripheral nervous systems, is a biologically active peptide which is strongly upregulated by nerve injury, estrogen and during...

Identification and characterization of the 5'-flanking region of the rat galanin gene (1998)

Zhang, Hong

Galanin, a neuropeptide widely distributed throughout the central and eripheral nervous systems, is a biologically active peptide which is strongly upregulated by nerve injury, estrogen and during...

Social transformations, family life, and uxorilocal marriages in a Hubei village, 1870-1994 (China) (1998)

Zhang, Hong

This dissertation examines the practice of uxorilocal marriage in Zhongshan, a rural community in Hubei Province of central China, over the course of the past century, documenting its rise and fall...

Modeling and design of optical limiters /--by Hong Zhang. (1998)

Zhang, Hong.

Thesis (M.S. in Engineering)--University of Wisconsin--Milwaukee, 1998.

Pseudospectra Of Companion Matrices And Their Potential Impact On Polynomial Algorithms (1998)

Simone Flory, Jamiiru Luttamaguzi, Michael Tisher, Hong Zhang

. Multivariate polynomial systems pervade engineering design, modeling and simulation. Algorithms for solving these systems form a a fundamental computational kernel in science and engineering. In...

Visual Servoing with Dynamics: Control of an Unmanned Blimp (1998)

Hong Zhang, James P. Ostrowski

Image-based control of free-flying mechanical systems is addressed, with application to an indoor, vision-guided blimp. A methodology is developed for performing visual servoing by incorporating the...

A Neural Networks Approach to Inverse Optimization (1998)

Hong Zhang And, Hong Zhang, Masumi Ishikawa

Proposed in this paper is a novel approach to inverse optimization problems by the learning of neural networks. Inverse optimization here means to estimate a positive semidefinite quadratic criterion...

Visual Servoing with Dynamics: Control of an Unmanned Blimp (1998)

Hong Zhang, James P. Ostrowski

Image-based control of free-flying mechanical systems is addressed, with application to an indoor visionguided blimp. A methodology is developed for incorporating the physical parameters of a...

A Bookkeeping Strategy for Multiple Objective Linear Programs. (1997)

Aurovillian, Alok, Zhang, Hong, Wiecek, Malgorzata M.

This paper discusses the bookkeeping strategies for solving large multiple objective linear programs (MOLPs) on ADBASE, a well developed sequential software package, and on a parallel ADBASE...

Fourier-Laplace Analysis of Multigrid Waveform Relaxation Method for Hyperbolic Equations. (1997)

Ta'asan, Shlomo, Zhang, Hong

The multigrid waveform relaxation (WR) algorithm has been fairly studied and implemented for parabolic equations. It has been found that the performance of the multigrid WR method for a parabolic...

Task Modelling (1997)

Rajiv Kishore, Hong Zhang, R. Ramesh, Ontological Engineering, Cecilia Rosenbloom, Ontologies Frameworks

Recently, there has been increasing recognition that ontological principles can be effectively applied to the broader field of information systems [5, 9]. This has led to the notion of...

The Use of Perceptual Cues in Multi-Robot Box-Pushing (1996)

Ronald Kube, Hong Zhang

In this paper we present an approach to controlling transitions in multi-robot tasks which have been modelled as a linear series of steps. A box-pushing task is described as a sequence of sub-tasks...

Dextrous Manipulation Planning by Grasp Transformation (1996)

Hong Zhang, Kazuo Tanie, Hitoshi Maekawa

A novel framework for dextrous manipulation planning based on transformations between canonical grasp con- gurations is proposed in this paper. The proposed approach is inspired by the observation...

Local Object Shape From Tactile Sensing (1996)

Ning Chen, Ray Rink, Hong Zhang

Studies on contact problems such as shape recovery from tactile sensing involve complex geometrics and kinematics. In the first part of the paper we introduce a convenient matrix expression of 3-D...

An Efficient Pixel-Based Technique for Visual Verification of 3-D Object Hypotheses (1996)

Michael Boshra, Hong Zhang

We present a pixel-based technique for visual verification of 3-D object hypotheses. The technique proceeds in three steps: Firstly, the visible-edge image of the hypothesized model object is...

O6-methylguanine induces intrachromosomal homologous recombination in human cells (1996)

Zhang, Hong, Tsujimura, Tohru, Bhattacharyya, Nitai P., Maher, Veronica M., McCormick, J.Justin

N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), which alkylates many positions in DNA including the O6 position of guanine, efficiently induces intrachromosomal homologous recombination in mouse...

Anionic polymerization of (meth)acrylic monomers. 22. Anionic polymerization of tert-butyl methacrylate in toluene/THF mixtures : a preliminary approach to the role of solvation/ligation equilibria (1995)

Wang, Jin-Shan, Zhang, Hong, Jérôme, Robert, Teyssié, Philippe

Although the anionic polymerization of tert-butyl methacrylate (tBMA) induces a narrow and unimodal molecular weight distribution (MWD) when performed in either pure THF or pure toluene at -78...

Alloxan toxicity to macrophages and insulinoma cells / (1995)

Zhang, Hong.

Thesis (doctoral)--Linköping University, 1995.

A Constraint-Satisfaction Approach for 3D Vision/Touch-Based Object Recognition (1995)

Michael Boshra, Hong Zhang

We present a technique for recognizing polyhedral objects by integrating visual and tactile data. The problem is formulated as a constraint-satisfaction problem (CSP) to provide a unified framework...

Analysis of code-division multiple access packet radio networks / (1994)

Zhang, Hong.

Thesis (Ph. D.)--Dept. of Electrical Engineering, University of Utah, 1994.

Stagnation Recovery Behaviours for Collective Robotics (1994)

C. Ronald Kube, Hong Zhang

Accomplishing useful tasks with a collection of decentralized mobile robots will require control methods that deal effectively with a number of unique problems that impede the system's progress....

Use of Visual and Tactile Data for Generation of 3-D Pose Hypotheses (1994)

Michael Boshra, Hong Zhang

Most existing 3-D object recognition/localization systems rely on a single type of sensory data, although several sensors may be available in a robot task to provide information about the objects to...

A Scalable Parallel Algorithm for Multiple Objective Linear Programs (1994)

Malgorzata M. Wiecek, Hong Zhang

This paper presents an ADBASE-based parallel algorithm for solving multiple objective linear programs (MOLPs). Job balance, speedup and scalability are of primary interest in evaluating efficiency of...

Regulation of glial cell development and axonal outgrowth in the vertebrate central nervous system (1993)

Zhang, Hong

The complex and diverse functions of the mature vertebrate central nervous system (CNS) depend on the precise interactions formed by many types of neural cells, including neurons and glial cells. The...

Regulation of glial cell development and axonal outgrowth in the vertebrate central nervous system (1993)

Zhang, Hong

The complex and diverse functions of the mature vertebrate central nervous system (CNS) depend on the precise interactions formed by many types of neural cells, including neurons and glial cells. The...

Controlling Collective Tasks With An ALN (1993)

Ronald Kube, Hong Zhang, Xiaohuan Wang

In this paper, we explore the idea of using an Adaptive Logic Network (ALN) [2] for behaviour arbitration. Our approach is to define the collective task, to be performed by multiple robots, as a...

Collective Robotics: From Social Insects to Robots (1993)

Ronald Kube, Hong Zhang

Achieving tasks with a multiple robot system will require a control system that is both simple and scalable as the number of robots increases. Collective behavior as demonstrated by social insects is...

Lectin binding by macroglial and microglial cells in the brains of young normal and myelin-deficient (md) mutant rats (1993)

Cammer, Wendy, Zhang, Hong

To distinguish macroglia (oligodendrocytes and astrocytes) from microglia in the brain, ‘markers’ that have been used in previous studies include carbonic anhydrase II (CAII) immunoreactivity for...

Attenuation of Sindbis virus neurovirulence by using defined mutations in nontranslated regions of the genome RNA (1992)

Kuhn, Richard J., Griffin, Diane E., Zhang, Hong, Niesters, Hubert G. M., Strauss, James H.

We examined a panel of Sindbis virus mutants containing defined mutations in the 5' nontranslated region of the genome RNA, in the 3' nontranslated region, or in both for their growth in cultured...

Mechanism of action of sphingosine in cell growth regulation /--by Hong Zhang. (1992)

Zhang, Hong.

Thesis (Ph. D.)--Georgetown University, Dept. of Biochemistry and Molecular Biology, 1992.

Reversible rectifiers. (1992)

Zhang, Hong.

Thesis (Ph. D.)--University of Surrey, 1992.

Collective Robotic Intelligence (1992)

C. Ronald Kube, Hong Zhang

In this paper, we examine the problem of controlling multiple behaviour-based autonomous robots. Based on observations made from the study of social insects, we propose five simple mechanisms used to...

Collective Task Achieving Group Behaviour by Multiple Robots (1992)

C. Ronald Kube, Hong Zhang

In this paper, we explore the idea of using environmental cues as a control for a chain of sequential behaviours which, when taken together, define a task achieving group behaviour. Our approach is...

In situ TEM study of intergranular fracture /--by Hong Zhang. (1991)

Zhang, Hong.

Thesis (Ph. D.)--State University of New York at Stony Brook, 1991.

A study of inference about the turning point in two phase regression /--by Hong Zhang. (1991)

Zhang, Hong

Thesis (M.S.)--University of Alabama at Birmingham, School of Joint Health Sciences.

Intelligent robotic system design /--by Hong Zhang. (1989)

Zhang, Hong

Thesis (M.S.)--California State University, Northridge, 1989.

Cytochrome B5 gene in chicken /--Hong Zhang. (1989)

Zhang, Hong.

Thesis (Ph. D.)--Michigan State University. Dept. of Genetics Program, 1989.

Cytochrome B5 gene in chicken--[microform] /--Hong Zhang. (1989)

Zhang, Hong.

Thesis (Ph. D.)--Michigan State University. Dept. of Genetics Program, 1989.

A Distributed System for Robot Manipulator Control (1988)

Paul, Richard P, Zhang, Hong, Hashimoto, Minoru, Izaguirre, Alberto, Trinkle, Jeffrey, Ulrich, Nathan, ...

This is the final report representing three years of work under the current grant. This work was directed to the development of a distributed computer architecture to function as a force and motion...

RFMS Software Reference Manual (1988)

Zhang, Hong

This manual explains the software of the Robot Force and Motion Server (RFMS), a high performance robot control system designed and implemented in the GRASP laboratory. In this system, the robot...

RFMS Source Code (1988)

Zhang, Hong

This is the source code of RFMS, a high performance robot control system designed and implemented in GRASP laboratory. It is intended to serve as a reference to "Software Reference Manual", prepared...

Design and Implementation of a Robot Force and Motion Server (1986)

Zhang, Hong

A robot manipulator is a force and motion server for a robot. The robot, interpreting sensor information in terms of a world model and a task plan, issues instructions to the manipulator to carry out...

Application of Data Mining Based on Artificial Immunity in Marketing (1970)

Jun Ju, Hong Zhang

Facing fierce market competition, how to make the effective marketing strategy rapidly according to the market demand is of vital importance to the survival and development of enterprises. Data...

J2EE Development Based on the JSED Template (1970)

Hui Li, Hong Zhang, Tiefeng Jin

This article proposes the JSED template which is directed by the MVC design pattern and behaves as the Session Facade design pattern, and then gives its working principle, finally introduces how to...

Formalization of Mining Association Rules based on Relational Database in EIS (1970)

Hong Zhang, Bo Zhang

In this paper, we study the concrete signification of association rules in relational database, and propose a new formalization and a general process of mining association rules, which is...

BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins

Zhang, Hong, Xu, Qunli, Krajewski, Stanislaw, Krajewska, Maryla, Xie, Zhihua, Fuess, Sally, ...

Two major pathways for induction of apoptosis have been identified—intrinsic and extrinsic. The extrinsic pathway is represented by tumor necrosis factor family receptors, which utilize protein...

12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced increase in depressed white blood cell counts in patients treated with cytotoxic cancer chemotherapeutic drugs

Han, Zheng Tao, Tong, Yun Ke, He, Lin Min, Zhang, Yang, Sun, Jun Zhong, Wang, Tian Yi, ...

Fifty-two patients with solid tumors had depressed white blood cell and neutrophil counts because of prior treatment with cytotoxic cancer chemotherapeutic drugs. These patients were given one or...

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

James, Thomas L., Liu, He, Ulyanov, Nikolai B., Farr-Jones, Shauna, Zhang, Hong, Donne, David G., ...

The scrapie prion protein (PrPSc) is the major, and possibly the only, component of the infectious prion; it is generated from the cellular isoform (PrPC) by a conformational change. N-terminal...

Structure of a cytochrome P450–redox partner electron-transfer complex

Sevrioukova, Irina F., Li, Huiying, Zhang, Hong, Peterson, Julian A., Poulos, Thomas L.

The crystal structure of the complex between the heme- and FMN-binding domains of bacterial cytochrome P450BM-3, a prototype for the complex between eukaryotic microsomal P450s and P450 reductase,...

Mutations in HYAL1, a member of a tandemly distributed multigene family encoding disparate hyaluronidase activities, cause a newly described lysosomal disorder, mucopolysaccharidosis IX

Triggs-Raine, Barbara, Salo, Timothy J., Zhang, Hong, Wicklow, Brandy A., Natowicz, Marvin R.

Hyaluronan (HA), a large glycosaminoglycan abundant in the extracellular matrix, is important in cell migration during embryonic development, cellular proliferation, and differentiation and has a...

Insulin Control of Glycogen Metabolism in Knockout Mice Lacking the Muscle-Specific Protein Phosphatase PP1G/RGL

Suzuki, Yoichi, Lanner, Carita, Kim, Jong-Hwa, Vilardo, Pier Giuseppe, Zhang, Hong, Yang, Jie, ...

The regulatory-targeting subunit (RGL, also called GM) of the muscle-specific glycogen-associated protein phosphatase PP1G targets the enzyme to glycogen where it modulates the activity of...

Antisense Oligonucleotide Inhibition of Hepatitis C Virus (HCV) Gene Expression in Livers of Mice Infected with an HCV-Vaccinia Virus Recombinant

Zhang, Hong, Hanecak, Ronnie, Brown-Driver, Vickie, Azad, Raana, Conklin, Boyd, Fox, Maureen C., ...

Hepatitis C virus (HCV) is the major cause of non-A, non-B hepatitis worldwide. Current treatments are not curative for most infected individuals, and there is an urgent need for both novel...

In Vitro Antimicrobial Properties of Recombinant ASABF, an Antimicrobial Peptide Isolated from the Nematode Ascaris suum

Zhang, Hong, Yoshida, Shigenobu, Aizawa, Tomoyasu, Murakami, Ritsuko, Suzuki, Masato, Koganezawa, Nozomu, ...

ASABF is a CSαβ-type antimicrobial peptide that contains four intramolecular disulfide bridges (Y. Kato and S. Komatsu, J. Biol. Chem. 271:30493–30498, 1996). In the present study, a recombinant...

Mice with a Targeted Deletion of the Tetranectin Gene Exhibit a Spinal Deformity

Iba, Kousuke, Durkin, Marian E., Johnsen, Lise, Hunziker, Ernst, Damgaard-Pedersen, Karen, Zhang, Hong, ...

Tetranectin is a plasminogen-binding, homotrimeric protein belonging to the C-type lectin family of proteins. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to...

UV-induced T→C transition at a TT photoproduct site is dependent on Saccharomyces cerevisiae polymerase η in vivo

Zhang, Hong, Siede, Wolfram

UV-induced reversion of the arg4-17 ochre allele in Saccharomyces cerevisiae is largely dependent on translesion polymerase η (Rad30p), known to bypass cyclobutane-type TT dimers in an error-free...

Identification of rCop-1, a New Member of the CCN Protein Family, as a Negative Regulator for Cell Transformation

Zhang, Rong, Averboukh, Lidia, Zhu, Weimin, Zhang, Hong, Jo, Hakryul, Dempsey, Peter J., ...

By using a model system for cell transformation mediated by the cooperation of the activated H-ras oncogene and the inactivated p53 tumor suppressor gene, rCop-1 was identified by mRNA differential...

Enzymes of the SUMO Modification Pathway Localize to Filaments of the Nuclear Pore Complex

Zhang, Hong, Saitoh, Hisato, Matunis, Michael J.

SUMOs are small ubiquitin-related polypeptides that are reversibly conjugated to many nuclear proteins. Although the number of identified substrates has grown rapidly, relatively little is still...

Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci

Zhang, Hong, Pan, Kuang-Hung, Cohen, Stanley N.

Replicative senescence is the state of irreversible proliferative arrest that occurs as a concomitant of progressive telomere shortening. By using cDNA microarrays and the gabriel system of computer...

AtCHIP, a U-Box-Containing E3 Ubiquitin Ligase, Plays a Critical Role in Temperature Stress Tolerance in Arabidopsis1

Yan, Juqiang, Wang, Jing, Li, Qingtian, Hwang, Jae Ryoung, Patterson, Cam, Zhang, Hong

The Arabidopsis gene AtCHIP encodes a protein with three tetratricopeptide repeats and a U-box domain, which is structurally similar to the animal CHIP proteins, a new class of E3 ubiquitin ligases....

The trp RNA-Binding Attenuation Protein of Bacillus subtilis Regulates Translation of the Tryptophan Transport Gene trpP (yhaG) by Blocking Ribosome Binding

Yakhnin, Helen, Zhang, Hong, Yakhnin, Alexander V., Babitzke, Paul

Expression of the Bacillus subtilis tryptophan biosynthetic genes (trpEDCFBA and pabA [trpG]) is regulated in response to tryptophan by TRAP, the trp RNA-binding attenuation protein. TRAP-mediated...

A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene

Zhang, Hong, Emmons, Scott W.

The Caenorhabditis elegans caudal homolog, pal-1, is required for neurogenesis in the male tail. We show that expression of pal-1 in the postembryonic neuroblast cell V6 can be initiated by two...

Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice

Tang, Xiuwei, Kim, Arianna L., Feith, David J., Pegg, Anthony E., Russo, Justin, Zhang, Hong, ...

Solar ultraviolet B (UVB) radiation induces cutaneous ornithine decarboxylase (ODC), the first enzyme in the polyamine-biosynthesis pathway, which drives continued proliferation and clonal expansion...

Identification of an Antigenic Determinant on the S2 Domain of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Capable of Inducing Neutralizing Antibodies

Zhang, Hong, Wang, Guangwen, Li, Jian, Nie, Yuchun, Shi, Xuanling, Lian, Gewei, ...

Severe acute respiratory syndrome (SARS) is a life-threatening disease caused by a newly identified coronavirus (CoV), SARS-CoV. The spike (S) glycoprotein of CoV is the major structural protein...

Neutrophil protein kinase Cδ as a mediator of stroke-reperfusion injury

Chou, Wen-Hai, Choi, Doo-Sup, Zhang, Hong, Mu, Dezhi, McMahon, Tom, Kharazia, Viktor N., ...

Thrombolysis is widely used to intervene in acute ischemic stroke, but reestablishment of circulation may paradoxically initiate a reperfusion injury. Here we describe studies with mice lacking...

Small Molecules Blocking the Entry of Severe Acute Respiratory Syndrome Coronavirus into Host Cells

Yi, Ling, Li, Zhengquan, Yuan, Kehu, Qu, Xiuxia, Chen, Jian, Wang, Guangwen, ...

Severe acute respiratory syndrome coronavirus (SARS-CoV) is the pathogen of SARS, which caused a global panic in 2003. We describe here the screening of Chinese herbal medicine-based, novel small...

Smurf2 up-regulation activates telomere-dependent senescence

Zhang, Hong, Cohen, Stanley N.

Progressive telomere shortening activates replicative senescence, which prevents somatic cells from being propagated indefinitely in culture. The limitation of proliferative capacity imposed by...

Analysis of Human Serum Immunoglobulin G against O-Acetyl-Positive and O-Acetyl-Negative Serogroup W135 Meningococcal Capsular Polysaccharide

Giardina, Peter C., Longworth, Emma, Evans-Johnson, Renee E., Bessette, Michaelene L., Zhang, Hong, Borrow, Ray, ...

The capsular polysaccharide of Neisseria meningitidis serogroup W135 is expressed in both O-acetyl-positive (OA+) and O-acetyl-negative (OA−) forms. This study investigates the impact of OA status...

Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity

Eguchi, Jun, Wada, Jun, Hida, Kazuyuki, Zhang, Hong, Matsuoka, Takashi, Baba, Masako, ...

Few cell adhesion molecules have been reported to be expressed in mature adipocytes, and the significance of cell adhesion process in adipocyte biology is also unknown. In the present study, we...

The Conserved Mec1/Rad53 Nuclear Checkpoint Pathway Regulates Mitochondrial DNA Copy Number in Saccharomyces cerevisiaeD⃞

Taylor, Sean D., Zhang, Hong, Eaton, Jana S., Rodeheffer, Matthew S., Lebedeva, Maria A., O'Rourke, Thomas W., ...

How mitochondrial DNA (mtDNA) copy number is determined and modulated according to cellular demands is largely unknown. Our previous investigations of the related DNA helicases Pif1p and Rrm3p...

Visceral adipose tissue-derived serine protease inhibitor: A unique insulin-sensitizing adipocytokine in obesity

Hida, Kazuyuki, Wada, Jun, Eguchi, Jun, Zhang, Hong, Baba, Masako, Seida, Aya, ...

There is a rapid global rise in obesity, and the link between obesity and diabetes remains somewhat obscure. We identified an adipocytokine, designated as visceral adipose tissue-derived serpin...

Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum

Pillai, Ajitha, Ueno, Satoshi, Zhang, Hong, Lee, Jae Min, Kato, Yusuke

Cecropin P1 was first identified as a mammalian antimicrobial peptide isolated from the pig intestine. Much research aimed at characterizing this peptide has been reported. Recently, the workers who...

abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans.

Kato, Yusuke, Aizawa, Tomoyasu, Hoshino, Hirokazu, Kawano, Keiichi, Nitta, Katsutoshi, Zhang, Hong

Two genes encoding the ASABF (Ascaris suum antibacterial factor)-type antimicrobial peptide, abf-1 and abf-2, were identified in Caenorhabditis elegans. Recombinant ABF-2 exhibited potent...

Induction of ASABF (Ascaris suum antibacterial factor)-type antimicrobial peptides by bacterial injection: novel members of ASABF in the nematode Ascaris suum.

Pillai, Ajitha, Ueno, Satoshi, Zhang, Hong, Kato, Yusuke

Recently, invertebrate models have been widely used for the study of innate immunity. Nematodes are novel potential candidates because of the experimental advantages of Caenorhabditis elegans....

Identification of a New Spore Wall Protein from Encephalitozoon cuniculi

Xu, Yanji, Takvorian, Peter, Cali, Ann, Wang, Fang, Zhang, Hong, Orr, George, ...

Microsporidia form environmentally resistant spores that are critical for their host-to-host transmission and persistence in the environment. The spore walls of these organisms are composed of two...

Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2

Toyofuku, Toshihiko, Zhang, Hong, Kumanogoh, Atsushi, Takegahara, Noriko, Suto, Fumikazu, Kamei, Junko, ...

Semaphorins, originally identified as axon guidance factors in the nervous system, play integral roles in organogenesis. Here, we demonstrate a critical involvement of Sema6D in cardiac...

Cost-Effectiveness of Earlier Initiation of Antiretroviral Therapy for Uninsured HIV-Infected Adults

Schackman, Bruce R., Goldie, Sue J., Weinstein, Milton C., Losina, Elena, Zhang, Hong, Freedberg, Kenneth A.

Objectives. This study was designed to examine the societal cost-effectiveness and the impact on government payers of earlier initiation of antiretroviral therapy for uninsured HIV-infected adults.

Caenorhabditis elegans unc-37/groucho interacts genetically with components of the transcriptional mediator complex.

Zhang, Hong, Emmons, Scott W

Groucho functions as a general corepressor by modulating chromatin structure and has a widespread role in many developmental processes. Here we show that Groucho may also interact with the basal...

Clinicopathological significance of stromal variables: angiogenesis, lymphangiogenesis, inflammatory infiltration, MMP and PINCH in colorectal carcinomas

Sun, Xiao-Feng, Zhang, Hong

Cancer research has mainly focused on alterations of genes and proteins in cancer cells themselves that result in either gain-of-function in oncogenes or loss-of-function in tumour-suppressor genes....

Heuristic scheduling of resource-constrained, multiple-mode and repetitive projects

Hong Zhang, Heng Li, C. M. Tam

An alternative heuristic method for scheduling repetitive projects in which resources are limited and activities may be executed with multiple modes of resource demands associated with different...

A biochemical rationale for the anticancer effects of Hsp90 inhibitors: Slow, tight binding inhibition by geldanamycin and its analogues

Gooljarsingh, Lata T., Fernandes, Christine, Yan, Kang, Zhang, Hong, Grooms, Michael, Johanson, Kyung, ...

Heat shock protein (Hsp)90 is emerging as an important therapeutic target for the treatment of cancer. Two analogues of the Hsp90 inhibitor geldanamycin are currently in clinical trials. Geldanamycin...

Crystal Structure of a Type III Pantothenate Kinase: Insight into the Mechanism of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria†

Yang, Kun, Eyobo, Yvonne, Brand, Leisl A., Martynowski, Dariusz, Tomchick, Diana, Strauss, Erick, ...

Pantothenate kinase (PanK) catalyzes the first step in the five-step universal pathway of coenzyme A (CoA) biosynthesis, a key transformation that generally also regulates the intracellular...

Altered Expression of TFF-1 and CES-2 in Barrett's Esophagus and Associated Adenocarcinomas1

Fox, Charles A, Sapinoso, Lisa M, Zhang, Hong, Zhang, Wanghai, McLeod, Howard L, Petroni, Gina R, ...

Identification of biomarkers to recognize individuals with Barrett's esophagus (BE) predisposed to develop malignancy is currently a pressing issue. We utilized gene expression profiling to compare...

Application of 23Na MRI to Monitor Chemotherapeutic Response in RIF-1 Tumors1

Babsky, Andriy M, Hekmatyar, Shahryar K, Zhang, Hong, Solomon, James L, Bansal, Navin

Effects of an alkylating anticancer drug, cyclophosphamide (Cp), on 23Na signal intensity (23Na SI) and water apparent diffusion coefficient (ADC) were examined in subcutaneously-implanted...

BAR: An apoptosis regulator at the intersection of caspases and Bcl-2 family proteins

Zhang, Hong, Xu, Qunli, Krajewski, Stanislaw, Krajewska, Maryla, Xie, Zhihua, Fuess, Sally, ...

Two major pathways for induction of apoptosis have been identified—intrinsic and extrinsic. The extrinsic pathway is represented by tumor necrosis factor family receptors, which utilize protein...

12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced increase in depressed white blood cell counts in patients treated with cytotoxic cancer chemotherapeutic drugs

Han, Zheng Tao, Tong, Yun Ke, He, Lin Min, Zhang, Yang, Sun, Jun Zhong, Wang, Tian Yi, ...

Fifty-two patients with solid tumors had depressed white blood cell and neutrophil counts because of prior treatment with cytotoxic cancer chemotherapeutic drugs. These patients were given one or...

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

James, Thomas L., Liu, He, Ulyanov, Nikolai B., Farr-Jones, Shauna, Zhang, Hong, Donne, David G., ...

The scrapie prion protein (PrPSc) is the major, and possibly the only, component of the infectious prion; it is generated from the cellular isoform (PrPC) by a conformational change. N-terminal...

Structure of a cytochrome P450–redox partner electron-transfer complex

Sevrioukova, Irina F., Li, Huiying, Zhang, Hong, Peterson, Julian A., Poulos, Thomas L.

The crystal structure of the complex between the heme- and FMN-binding domains of bacterial cytochrome P450BM-3, a prototype for the complex between eukaryotic microsomal P450s and P450 reductase,...

Mutations in HYAL1, a member of a tandemly distributed multigene family encoding disparate hyaluronidase activities, cause a newly described lysosomal disorder, mucopolysaccharidosis IX

Triggs-Raine, Barbara, Salo, Timothy J., Zhang, Hong, Wicklow, Brandy A., Natowicz, Marvin R.

Hyaluronan (HA), a large glycosaminoglycan abundant in the extracellular matrix, is important in cell migration during embryonic development, cellular proliferation, and differentiation and has a...

Insulin Control of Glycogen Metabolism in Knockout Mice Lacking the Muscle-Specific Protein Phosphatase PP1G/RGL

Suzuki, Yoichi, Lanner, Carita, Kim, Jong-Hwa, Vilardo, Pier Giuseppe, Zhang, Hong, Yang, Jie, ...

The regulatory-targeting subunit (RGL, also called GM) of the muscle-specific glycogen-associated protein phosphatase PP1G targets the enzyme to glycogen where it modulates the activity of...

Antisense Oligonucleotide Inhibition of Hepatitis C Virus (HCV) Gene Expression in Livers of Mice Infected with an HCV-Vaccinia Virus Recombinant

Zhang, Hong, Hanecak, Ronnie, Brown-Driver, Vickie, Azad, Raana, Conklin, Boyd, Fox, Maureen C., ...

Hepatitis C virus (HCV) is the major cause of non-A, non-B hepatitis worldwide. Current treatments are not curative for most infected individuals, and there is an urgent need for both novel...

In Vitro Antimicrobial Properties of Recombinant ASABF, an Antimicrobial Peptide Isolated from the Nematode Ascaris suum

Zhang, Hong, Yoshida, Shigenobu, Aizawa, Tomoyasu, Murakami, Ritsuko, Suzuki, Masato, Koganezawa, Nozomu, ...

ASABF is a CSαβ-type antimicrobial peptide that contains four intramolecular disulfide bridges (Y. Kato and S. Komatsu, J. Biol. Chem. 271:30493–30498, 1996). In the present study, a recombinant...

Mice with a Targeted Deletion of the Tetranectin Gene Exhibit a Spinal Deformity

Iba, Kousuke, Durkin, Marian E., Johnsen, Lise, Hunziker, Ernst, Damgaard-Pedersen, Karen, Zhang, Hong, ...

Tetranectin is a plasminogen-binding, homotrimeric protein belonging to the C-type lectin family of proteins. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to...

UV-induced T→C transition at a TT photoproduct site is dependent on Saccharomyces cerevisiae polymerase η in vivo

Zhang, Hong, Siede, Wolfram

UV-induced reversion of the arg4-17 ochre allele in Saccharomyces cerevisiae is largely dependent on translesion polymerase η (Rad30p), known to bypass cyclobutane-type TT dimers in an error-free...

Identification of rCop-1, a New Member of the CCN Protein Family, as a Negative Regulator for Cell Transformation

Zhang, Rong, Averboukh, Lidia, Zhu, Weimin, Zhang, Hong, Jo, Hakryul, Dempsey, Peter J., ...

By using a model system for cell transformation mediated by the cooperation of the activated H-ras oncogene and the inactivated p53 tumor suppressor gene, rCop-1 was identified by mRNA differential...

Enzymes of the SUMO Modification Pathway Localize to Filaments of the Nuclear Pore Complex

Zhang, Hong, Saitoh, Hisato, Matunis, Michael J.

SUMOs are small ubiquitin-related polypeptides that are reversibly conjugated to many nuclear proteins. Although the number of identified substrates has grown rapidly, relatively little is still...

Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci

Zhang, Hong, Pan, Kuang-Hung, Cohen, Stanley N.

Replicative senescence is the state of irreversible proliferative arrest that occurs as a concomitant of progressive telomere shortening. By using cDNA microarrays and the gabriel system of computer...

AtCHIP, a U-Box-Containing E3 Ubiquitin Ligase, Plays a Critical Role in Temperature Stress Tolerance in Arabidopsis1

Yan, Juqiang, Wang, Jing, Li, Qingtian, Hwang, Jae Ryoung, Patterson, Cam, Zhang, Hong

The Arabidopsis gene AtCHIP encodes a protein with three tetratricopeptide repeats and a U-box domain, which is structurally similar to the animal CHIP proteins, a new class of E3 ubiquitin ligases....

The trp RNA-Binding Attenuation Protein of Bacillus subtilis Regulates Translation of the Tryptophan Transport Gene trpP (yhaG) by Blocking Ribosome Binding

Yakhnin, Helen, Zhang, Hong, Yakhnin, Alexander V., Babitzke, Paul

Expression of the Bacillus subtilis tryptophan biosynthetic genes (trpEDCFBA and pabA [trpG]) is regulated in response to tryptophan by TRAP, the trp RNA-binding attenuation protein. TRAP-mediated...

A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene

Zhang, Hong, Emmons, Scott W.

The Caenorhabditis elegans caudal homolog, pal-1, is required for neurogenesis in the male tail. We show that expression of pal-1 in the postembryonic neuroblast cell V6 can be initiated by two...

Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2

Toyofuku, Toshihiko, Zhang, Hong, Kumanogoh, Atsushi, Takegahara, Noriko, Suto, Fumikazu, Kamei, Junko, ...

Semaphorins, originally identified as axon guidance factors in the nervous system, play integral roles in organogenesis. Here, we demonstrate a critical involvement of Sema6D in cardiac...

Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice

Tang, Xiuwei, Kim, Arianna L., Feith, David J., Pegg, Anthony E., Russo, Justin, Zhang, Hong, ...

Solar ultraviolet B (UVB) radiation induces cutaneous ornithine decarboxylase (ODC), the first enzyme in the polyamine-biosynthesis pathway, which drives continued proliferation and clonal expansion...

Identification of an Antigenic Determinant on the S2 Domain of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Capable of Inducing Neutralizing Antibodies

Zhang, Hong, Wang, Guangwen, Li, Jian, Nie, Yuchun, Shi, Xuanling, Lian, Gewei, ...

Severe acute respiratory syndrome (SARS) is a life-threatening disease caused by a newly identified coronavirus (CoV), SARS-CoV. The spike (S) glycoprotein of CoV is the major structural protein...

Neutrophil protein kinase Cδ as a mediator of stroke-reperfusion injury

Chou, Wen-Hai, Choi, Doo-Sup, Zhang, Hong, Mu, Dezhi, McMahon, Tom, Kharazia, Viktor N., ...

Thrombolysis is widely used to intervene in acute ischemic stroke, but reestablishment of circulation may paradoxically initiate a reperfusion injury. Here we describe studies with mice lacking...

Small Molecules Blocking the Entry of Severe Acute Respiratory Syndrome Coronavirus into Host Cells

Yi, Ling, Li, Zhengquan, Yuan, Kehu, Qu, Xiuxia, Chen, Jian, Wang, Guangwen, ...

Severe acute respiratory syndrome coronavirus (SARS-CoV) is the pathogen of SARS, which caused a global panic in 2003. We describe here the screening of Chinese herbal medicine-based, novel small...

Smurf2 up-regulation activates telomere-dependent senescence

Zhang, Hong, Cohen, Stanley N.

Progressive telomere shortening activates replicative senescence, which prevents somatic cells from being propagated indefinitely in culture. The limitation of proliferative capacity imposed by...

Analysis of Human Serum Immunoglobulin G against O-Acetyl-Positive and O-Acetyl-Negative Serogroup W135 Meningococcal Capsular Polysaccharide

Giardina, Peter C., Longworth, Emma, Evans-Johnson, Renee E., Bessette, Michaelene L., Zhang, Hong, Borrow, Ray, ...

The capsular polysaccharide of Neisseria meningitidis serogroup W135 is expressed in both O-acetyl-positive (OA+) and O-acetyl-negative (OA−) forms. This study investigates the impact of OA status...

Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity

Eguchi, Jun, Wada, Jun, Hida, Kazuyuki, Zhang, Hong, Matsuoka, Takashi, Baba, Masako, ...

Few cell adhesion molecules have been reported to be expressed in mature adipocytes, and the significance of cell adhesion process in adipocyte biology is also unknown. In the present study, we...

The Conserved Mec1/Rad53 Nuclear Checkpoint Pathway Regulates Mitochondrial DNA Copy Number in Saccharomyces cerevisiaeD⃞

Taylor, Sean D., Zhang, Hong, Eaton, Jana S., Rodeheffer, Matthew S., Lebedeva, Maria A., O'Rourke, Thomas W., ...

How mitochondrial DNA (mtDNA) copy number is determined and modulated according to cellular demands is largely unknown. Our previous investigations of the related DNA helicases Pif1p and Rrm3p...

Visceral adipose tissue-derived serine protease inhibitor: A unique insulin-sensitizing adipocytokine in obesity

Hida, Kazuyuki, Wada, Jun, Eguchi, Jun, Zhang, Hong, Baba, Masako, Seida, Aya, ...

There is a rapid global rise in obesity, and the link between obesity and diabetes remains somewhat obscure. We identified an adipocytokine, designated as visceral adipose tissue-derived serpin...

Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum

Pillai, Ajitha, Ueno, Satoshi, Zhang, Hong, Lee, Jae Min, Kato, Yusuke

Cecropin P1 was first identified as a mammalian antimicrobial peptide isolated from the pig intestine. Much research aimed at characterizing this peptide has been reported. Recently, the workers who...

abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans.

Kato, Yusuke, Aizawa, Tomoyasu, Hoshino, Hirokazu, Kawano, Keiichi, Nitta, Katsutoshi, Zhang, Hong

Two genes encoding the ASABF (Ascaris suum antibacterial factor)-type antimicrobial peptide, abf-1 and abf-2, were identified in Caenorhabditis elegans. Recombinant ABF-2 exhibited potent...

Induction of ASABF (Ascaris suum antibacterial factor)-type antimicrobial peptides by bacterial injection: novel members of ASABF in the nematode Ascaris suum.

Pillai, Ajitha, Ueno, Satoshi, Zhang, Hong, Kato, Yusuke

Recently, invertebrate models have been widely used for the study of innate immunity. Nematodes are novel potential candidates because of the experimental advantages of Caenorhabditis elegans....

Identification of a New Spore Wall Protein from Encephalitozoon cuniculi

Xu, Yanji, Takvorian, Peter, Cali, Ann, Wang, Fang, Zhang, Hong, Orr, George, ...

Microsporidia form environmentally resistant spores that are critical for their host-to-host transmission and persistence in the environment. The spore walls of these organisms are composed of two...

Cost-Effectiveness of Earlier Initiation of Antiretroviral Therapy for Uninsured HIV-Infected Adults

Schackman, Bruce R., Goldie, Sue J., Weinstein, Milton C., Losina, Elena, Zhang, Hong, Freedberg, Kenneth A.

Objectives. This study was designed to examine the societal cost-effectiveness and the impact on government payers of earlier initiation of antiretroviral therapy for uninsured HIV-infected adults.

A biochemical rationale for the anticancer effects of Hsp90 inhibitors: Slow, tight binding inhibition by geldanamycin and its analogues

Gooljarsingh, Lata T., Fernandes, Christine, Yan, Kang, Zhang, Hong, Grooms, Michael, Johanson, Kyung, ...

Heat shock protein (Hsp)90 is emerging as an important therapeutic target for the treatment of cancer. Two analogues of the Hsp90 inhibitor geldanamycin are currently in clinical trials. Geldanamycin...

Caenorhabditis elegans unc-37/groucho interacts genetically with components of the transcriptional mediator complex.

Zhang, Hong, Emmons, Scott W

Groucho functions as a general corepressor by modulating chromatin structure and has a widespread role in many developmental processes. Here we show that Groucho may also interact with the basal...

Altered Expression of TFF-1 and CES-2 in Barrett's Esophagus and Associated Adenocarcinomas1

Fox, Charles A, Sapinoso, Lisa M, Zhang, Hong, Zhang, Wanghai, McLeod, Howard L, Petroni, Gina R, ...

Identification of biomarkers to recognize individuals with Barrett's esophagus (BE) predisposed to develop malignancy is currently a pressing issue. We utilized gene expression profiling to compare...

Application of 23Na MRI to Monitor Chemotherapeutic Response in RIF-1 Tumors1

Babsky, Andriy M, Hekmatyar, Shahryar K, Zhang, Hong, Solomon, James L, Bansal, Navin

Effects of an alkylating anticancer drug, cyclophosphamide (Cp), on 23Na signal intensity (23Na SI) and water apparent diffusion coefficient (ADC) were examined in subcutaneously-implanted...

Crystal Structure of a Type III Pantothenate Kinase: Insight into the Mechanism of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria†

Yang, Kun, Eyobo, Yvonne, Brand, Leisl A., Martynowski, Dariusz, Tomchick, Diana, Strauss, Erick, ...

Pantothenate kinase (PanK) catalyzes the first step in the five-step universal pathway of coenzyme A (CoA) biosynthesis, a key transformation that generally also regulates the intracellular...

Clinicopathological significance of stromal variables: angiogenesis, lymphangiogenesis, inflammatory infiltration, MMP and PINCH in colorectal carcinomas

Sun, Xiao-Feng, Zhang, Hong

Cancer research has mainly focused on alterations of genes and proteins in cancer cells themselves that result in either gain-of-function in oncogenes or loss-of-function in tumour-suppressor genes....

Molecular epidemiology of measles viruses in China, 1995–2003

Zhang, Yan, Zhu, Zhen, Rota, Paul A, Jiang, Xiaohong, Hu, Jiayu, Wang, Jianguo, ...

This report describes the genetic characterization of 297 wild-type measles viruses that were isolated in 24 provinces of China between 1995 and 2003. Phylogenetic analysis of the N gene sequences...

The Role for HNF-1β-Targeted Collectrin in Maintenance of Primary Cilia and Cell Polarity in Collecting Duct Cells

Zhang, Yanling, Wada, Jun, Yasuhara, Akihiro, Iseda, Izumi, Eguchi, Jun, Fukui, Kenji, ...

Collectrin, a homologue of angiotensin converting enzyme 2 (ACE2), is a type I transmembrane protein, and we originally reported its localization to the cytoplasm and apical membrane of collecting...

Role of PTCH and p53 Genes in Early-Onset Basal Cell Carcinoma

Zhang, Hong, Ping, Xiao Li, Lee, Patricia K., Wu, Xiu Li, Yao, Ya Juan, Zhang, Ming Jian, ...

Basal cell carcinoma (BCC) is the most common skin cancer in the Western world. Ultraviolet (UV) exposure, race, age, gender, and decreased DNA repair capacity are known risk factors for the...

Down-Modulation of Monocyte Transendothelial Migration and Endothelial Adhesion Molecule Expression by Fibroblast Growth Factor : Reversal by the Anti-Angiogenic Agent SU6668

Zhang, Hong, Issekutz, Andrew C.

Basic and acidic fibroblast growth factor (bFGF and aFGF, respectively) and vascular endothelial growth factor (VEGF) exert angiogenic actions and have a role in wound healing, inflammation, and...

Polycomb-like genes are necessary for specification of dopaminergic and serotonergic neurons in Caenorhabditis elegans

Yang, Yong, Sun, Yinyan, Luo, Xin, Zhang, Yuxia, Chen, Yaoyao, Tian, E., ...

The molecular mechanisms underlying the formation of neurons with defined neurotransmitters are not well understood. In this study, we demonstrate that the PcG-like genes in Caenorhabditis elegans,...

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

Graff, Jeremy R., Konicek, Bruce W., Vincent, Thomas M., Lynch, Rebecca L., Monteith, David, Weir, Spring N., ...

Expression of eukaryotic translation initiation factor 4E (eIF4E) is commonly elevated in human and experimental cancers, promoting angiogenesis and tumor growth. Elevated eIF4E levels selectively...

Lance-Adams syndrome: a report of two cases*

Zhang, Yan-xing, Liu, Jian-ren, Jiang, Biao, Liu, Hui-qin, Ding, Mei-ping, Song, Shui-jiang, ...

Chronic post-hypoxic myoclonus, also known as Lance-Adams syndrome (LAS), is a rare complication of successful cardiopulmanry resuscitation often accompanied by action myoclonus and cerebellar...

The Flightless I Homolog, fli-1, Regulates Anterior/Posterior Polarity, Asymmetric Cell Division and Ovulation During Caenorhabditis elegans Development

Deng, Hansong, Xia, Dan, Fang, Bin, Zhang, Hong

Flightless I (Fli I) is an evolutionarily conserved member of the gelsolin family, containing actin-binding and severing activity in vitro. The physiological function of Fli I during animal...

Neutrophil histamine contributes to inflammation in mycoplasma pneumonia

Xu, Xiang, Zhang, Dongji, Zhang, Hong, Wolters, Paul J., Killeen, Nigel P., Sullivan, Brandon M., ...

Mycoplasmas cause chronic inflammation and are implicated in asthma. Mast cells defend against mycoplasma infection and worsen allergic inflammation, which is mediated partly by histamine. To address...

Involvement of tyrosine kinases, Ca2+ and PKC in activation of mitogen-activated protein (MAP) kinase in human polymorphonuclear neutrophils

Zhang, Hong, Garlichs, Christoph D, Mügge, Andreas, Daniel, Werner G

Activation of mitogen-activated protein (MAP) kinase is an early response to a wide variety of stimuli and plays an important role in the regulation of cellular functions. In the present study we...

Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling

Mi, Tiejuan, Abbasi, Shahrzad, Zhang, Hong, Uray, Karen, Chunn, Janci L., Xia, Ling Wei, ...

Priapism, abnormally prolonged penile erection in the absence of sexual excitation, is associated with ischemia-mediated erectile tissue damage and subsequent erectile dysfunction. It is common among...

The impact of China's accession to the WTO on its economy: an imperfect competitive CGE analysis

Hong Zhang

To examine the impact of trade barrier reductions on the Chinese economy following its WTO accession, a single-country, static CGE (Computable General Equilibrium) model is constructed, which...

Transcriptional regulation of NAD metabolism in bacteria: genomic reconstruction of NiaR (YrxA) regulon

Rodionov, Dmitry A., Li, Xiaoqing, Rodionova, Irina A., Yang, Chen, Sorci, Leonardo, Dervyn, Etienne, ...

A comparative genomic approach was used to reconstruct transcriptional regulation of NAD biosynthesis in bacteria containing orthologs of Bacillus subtilis gene yrxA, a previously identified...

Transcriptional regulation of NAD metabolism in bacteria: NrtR family of Nudix-related regulators

Rodionov, Dmitry A., De Ingeniis, Jessica, Mancini, Chiara, Cimadamore, Flavio, Zhang, Hong, Osterman, Andrei L., ...

A novel family of transcription factors responsible for regulation of various aspects of NAD synthesis in a broad range of bacteria was identified by comparative genomics approach. Regulators of this...

Estimating the Dynamics of Mutual Fund Alphas and Betas

Matthew I. Spiegel, Harry Mamaysky, Hong Zhang

Consider an economy in which the underlying security returns follow a linear factor model with constant coefficients. While portfolios that invest in these securities will, in general, have a linear...

The Caenorhabditis elegans PcG-like Gene sop-2 Regulates the Temporal and Sexual Specificities of Cell Fates

Cai, Qingchun, Sun, Yinyan, Huang, Xinxin, Guo, Cong, Zhang, Yuxia, Zhu, Zuoyan, ...

How spatial, temporal, and sexual specific cues are integrated to specify distinct cell fates during multicellular organism development is largely unknown. Here we demonstrate that the Caenorhabditis...

Identification and Characterization of an Archaeon-Specific Riboflavin Kinase▿

Mashhadi, Zahra, Zhang, Hong, Xu, Huimin, White, Robert H.

The riboflavin kinase in Methanocaldococcus jannaschii has been identified as the product of the MJ0056 gene. Recombinant expression of the MJ0056 gene in Escherichia coli led to a large increase in...

Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease

Trinchese, Fabrizio, Fa’, Mauro, Liu, Shumin, Zhang, Hong, Hidalgo, Ariel, Schmidt, Stephen D., ...

Calpains are calcium-dependent enzymes that determine the fate of proteins through regulated proteolytic activity. Calpains have been linked to the modulation of memory and are key to the...

Radio frequency analog electronics based on carbon nanotube transistors

Kocabas, Coskun, Kim, Hoon-sik, Banks, Tony, Rogers, John A., Pesetski, Aaron A., Baumgardner, James E., ...

The potential to exploit single-walled carbon nanotubes (SWNTs) in advanced electronics represents a continuing, major source of interest in these materials. However, scalable integration of SWNTs...

OSCILLATION CRITERIA FOR A CLASS OF SECOND-ORDER IMPULSIVE DELAY DIFFERENCE EQUATIONS

HONG ZHANG, LANSUN CHEN

This paper is devoted to the investigation of the oscillation of a class of second-order nonlinear impulsive delay difference equations. Some interesting results are obtained, and some examples which...

Analysis of least absolute deviation

Hong Zhang, Lincheng Zhao

We develop a unified L1-based analysis-of-variance-type method for testing linear hypotheses. Like the classical L2-based analysis of variance, the method is coordinate-free in the sense that it is...

Amino acid copolymer-specific IL-10-secreting regulatory T cells that ameliorate autoimmune diseases in mice

Stern, Joel N. H., Keskin, Derin B., Zhang, Hong, Lv, HuiJuan, Kato, Zenichiro, Strominger, Jack L.

IL-10-secreting regulatory T cell lines specific to glatiramer acetate [poly(Y,E,A,K)n] or poly(Y,F,A,K)n have been established from the enlarged spleen and lymph nodes that result from copolymer...

Small Molecule, Non-Peptide p75NTR Ligands Inhibit Aβ-Induced Neurodegeneration and Synaptic Impairment

Yang, Tao, Knowles, Juliet K., Lu, Qun, Zhang, Hong, Arancio, Ottavio, Moore, Laura A., ...

The p75 neurotrophin receptor (p75NTR) is expressed by neurons particularly vulnerable in Alzheimer's disease (AD). We tested the hypothesis that non-peptide, small molecule p75NTR ligands found to...

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Aβ accumulation

Muhammad, Alim, Flores, Ingrid, Zhang, Hong, Yu, Rui, Staniszewski, Agnieszka, Planel, Emmanuel, ...

Although deficiencies in the retromer sorting pathway have been linked to late-onset Alzheimer's disease, whether these deficiencies underlie the disease remains unknown. Here we characterized two...

Slit2 Inhibits Growth and Metastasis of Fibrosarcoma and Squamous Cell Carcinoma1

Kim, Hee Kyung, Zhang, Hong, Li, Hui, Wu, Tsung-Teh, Swisher, Stephen, He, Donggou, ...

Slits are a group of secreted glycoproteins that play a role in the regulation of cell migration. Previous studies suggested that Slit2 might be a tumor-suppressor gene. However, it remained to be...

An explicit representation of the limit of the LRT for interval mapping of quantitative trait loci

Zhang, Hong, Chen, Hanfeng, Li, Zhaohai

Consider the interval mapping method for quantitative trait loci (QTL) detection of an experimental organism in a backcross population. In a recent paper, Chen and Chen [2005. On some statistical...

Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome

Voronov, Sergey V., Frere, Samuel G., Giovedi, Silvia, Pollina, Elizabeth A., Borel, Christelle, Zhang, Hong, ...

Phosphatidylinositol-4,5-bisphosphate [PtdIns(4,5)P2] is a signaling phospholipid implicated in a wide variety of cellular functions. At synapses, where normal PtdIns(4,5)P2 balance is required for...

Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis

Ma, Feng, Ebihara, Yasuhiro, Umeda, Katsutsugu, Sakai, Hiromi, Hanada, Sachiyo, Zhang, Hong, ...

A critical issue for clinical utilization of human ES cells (hESCs) is whether they can generate terminally mature progenies with normal function. We recently developed a method for efficient...

Genetic diagnosis strategy of hereditary non-polyposis colorectal cancer

Sheng, Jian-Qiu, Zhang, Hong, Ji, Min, Fu, Lei, Mu, Hong, Zhang, Ming-Zhi, ...

AIM: To study the characteristics of mismatch repair gene mutation of Chinese hereditary non-polyposis colorectal cancer (HNPCC) and hMLH1 gene promoter methylation, and to improve the screening...

Dances with leukocytes: how tetraspanin-enriched microdomains assemble to form endothelial adhesive platforms

Ley, Klaus, Zhang, Hong

Rather than just providing an unstructured adhesive surface for leukocytes, cytokine-activated endothelial cells assemble preexisting tetraspanin-enriched microdomains to form endothelial adhesive...

Excess false positive rate caused by population stratification and disease rate heterogeneity in case-control association studies

Li, Zhaohai, Zhang, Hong, Zheng, Gang, Gastwirth, Joseph L., Gail, Mitchell H.

Case-control association studies using unrelated cases and controls may suffer from potential confounding due to population stratification. Bias and variance distortion caused by population...

Improved Forecasting of Mutual Fund Alphas and Betas

Harry Mamaysky, Matthew Spiegel, Hong Zhang

This paper proposes a simple back testing procedure that is shown to dramatically improve a panel data model's ability to produce out of sample forecasts. Here the procedure is used to forecast...

The Human Immunodeficiency Virus Type 1 Envelope Confers Higher Rates of Replicative Fitness to Perinatally Transmitted Viruses than to Nontransmitted Viruses ▿ †

Kong, Xiaohong, West, John T., Zhang, Hong, Shea, Danielle M., M'soka, Tendai J., Wood, Charles

Selection of a minor viral genotype during perinatal transmission of human Immunodeficiency virus type 1 (HIV-1) has been observed, but there is a lack of information on the correlation of the...

Management Strategy for Congenital Choledochal Cyst with Co-existing Intrahepatic Dilation and Aberrant Bile Duct As Well As Other Complicated Biliary Anomalies

Dong, Qian, Jiang, Buxian, Zhang, Hong, Jiang, Zhong, Lu, Hongting, Yang, Chuanmin, ...

The purpose of this study was to investigate and discuss imaging methods and management strategies for congenital choledochal cyst with co-existing intrahepatic dilation and aberrant bile duct as...

Apoptosis of human pancreatic cancer cells induced by Triptolide

Zhou, Guo-Xiong, Ding, Xiao-Ling, Huang, Jie-Fei, Zhang, Hong, Wu, Sheng-Bao, Cheng, Jian-Ping, ...

AIM: To investigate apoptosis in human pancreatic cancer cells induced by Triptolide (TL), and the relationship between this apoptosis and expression of caspase-3’ bcl-2 and bax.

Genome-wide Copy-Number-Variation Study Identified a Susceptibility Gene, UGT2B17, for Osteoporosis

Yang, Tie-Lin, Chen, Xiang-Ding, Guo, Yan, Lei, Shu-Feng, Wang, Jin-Tang, Zhou, Qi, ...

Osteoporosis, a highly heritable disease, is characterized mainly by low bone-mineral density (BMD), poor bone geometry, and/or osteoporotic fractures (OF). Copy-number variation (CNV) has been shown...

Granulomatous hypophysitis: two case reports and literature review

Shi, Jian, Zhang, Jian-min, Wu, Qun, Chen, Gao, Zhang, Hong, Bo, Wen-liang

Granulomatous hypophysitis (GRH) is extremely rare and commonly presents with chronic inflammatory of the enlarged pituitary gland. In our study, 66-year-old and 57-year-old women, both Chinese, were...

Neutralization-Sensitive R5-Tropic Simian-Human Immunodeficiency Virus SHIV-2873Nip, Which Carries env Isolated from an Infant with a Recent HIV Clade C Infection▿

Siddappa, Nagadenahalli B., Song, Ruijiang, Kramer, Victor G., Chenine, Agnès-Laurence, Velu, Vijayakumar, Ong, Helena, ...

Human immunodeficiency virus clade C (HIV-C) accounts for >56% of all HIV infections worldwide. To investigate vaccine safety and efficacy in nonhuman primates, a pathogenic, R5-tropic,...

Positive feedback regulation of maize NADPH oxidase by mitogen-activated protein kinase cascade in abscisic acid signalling

Lin, Fan, Ding, Haidong, Wang, Jinxiang, Zhang, Hong, Zhang, Aying, Zhang, Yun, ...

In maize (Zea mays), abscisic acid (ABA)-induced H2O2 production activates a 46 kDa mitogen-activated protein kinase (p46MAPK), and the activation of p46MAPK also regulates the production of H2O2....

Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis

Sorci, Leonardo, Martynowski, Dariusz, Rodionov, Dmitry A., Eyobo, Yvonne, Zogaj, Xhavit, Klose, Karl E., ...

Enzymes involved in the last 2 steps of nicotinamide adenine dinucleotide (NAD) cofactor biosynthesis, which catalyze the adenylylation of the nicotinic acid mononucleotide (NaMN) precursor to...

T cell receptors in an IL-10-secreting amino acid copolymer-specific regulatory T cell line that mediates bystander immunosuppression

Zhang, Hong, Stern, Joel N. H., Strominger, Jack L.

The T cell receptors from the regulatory IL-10-secreting T cell line induced by the random amino acid copolymers poly(F,Y,A,K,)n in SJL mice (H-2s) have been characterized, cloned, sequenced and...

Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARγ

Liu, Yi, Jia, Lei, Liu, Zun Chang, Zhang, Hong, Zhang, Peng Ju, Wan, Qiang, ...

Early stage diabetic nephropathy is characterized by elevated glomerular filtration. Recent studies have identified high-glucose induced p38 MAPK (p38) over-activation in mesangial cells. Mesangial...

CCR7 regulates B16 murine melanoma cell tumorigenesis in skin

Fang, Lei, Lee, Vivian C., Cha, Emily, Zhang, Hong, Hwang, Sam T.

Tumor cell-associated chemokine receptors play distinct roles in cancer biology, including enhancement of lymph node (LN) metastasis. To determine if CCR7 influences tumor formation in skin, we...

Antimicrobial Susceptibility of Mycoplasma pneumoniae Isolates and Molecular Analysis of Macrolide-Resistant Strains from Shanghai, China ▿

Liu, Yang, Ye, Xinyu, Zhang, Hong, Xu, Xiaogang, Li, Wanhua, Zhu, Demei, ...

Fifty-three Mycoplasma pneumoniae strains were isolated from pediatric patients in Shanghai, China, from October 2005 to February 2008. Of 53 clinical isolates, 44 (83%) were resistant to...