Hong Zhu

Publication List Details

Period

1989 - 2009

Number

121

Co-Authors

Analyzing Bivariate Survival Data with Interval Sampling and Application to Cancer Epidemiology (2009)

Zhu, Hong, Wang, Mei-Cheng

In medical follow-up studies, ordered bivariate survival data are frequently encountered when bivariate failure events are used as the outcomes to identify the progression of a disease. In cancer...

Analyzing Bivariate Survival Data with Interval Sampling and Application to Cancer Epidemiology (2009)

Zhu, Hong, Wang, Mei-Cheng

In medical follow-up studies, ordered bivariate survival data are frequently encountered when bivariate failure events are used as the outcomes to identify the progression of a disease. In cancer...

Analyzing Bivariate Survival Data with Interval Sampling and Application to Cancer Epidemiology (2009)

Zhu, Hong, Wang, Mei-Cheng

In medical follow-up studies, ordered bivariate survival data are frequently encountered when bivariate failure events are used as the outcomes to identify the progression of a disease. In cancer...

Analyzing Bivariate Survival Data with Interval Sampling and Application to Cancer Epidemiology (2009)

Zhu, Hong, Wang, Mei-Cheng

In medical follow-up studies, ordered bivariate survival data are frequently encountered when bivariate failure events are used as the outcomes to identify the progression of a disease. In cancer...

Screening of specific diagnostic peptides of swine hepatitis E virus (2009)

Zhao, Kai, Liu, Qiwen, Yu, Ruisong, Li, Zhen, Li, Jianyue, Zhu, Hong, ...

Abstract Background Swine hepatitis E virus (swHEV) is a zoonotic disease that is considered a major problem in pig production and presents a threat to human health. Elucidation of the major...

Online OVSF Code Assignment with Resource Augmentation (2009)

Francisy. L. Chin, Yong Zhang, Hong Zhu

Abstract. Orthogonal Variable Spreading Factor (OVSF) code assignment is a fundamental problem in Wideband Code-Division Multiple-Access (W-CDMA) systems, which play an important role in third...

Efficient Algorithms for k-Disjoint Paths Problems on DAGs ⋆ (2009)

Rudolf Fleischer, Qi Ge, Jian Li, Hong Zhu

Abstract. Given an acyclic directed graph and two distinct nodes s and t, we consider the problem of finding k disjoint paths from s to t satisfying some objective. We consider four objectives,...

Active academic communication across the Pacific: The experience of Chinese academic diasporas in the United States (2009)

Zhu, Hong

Today the diaspora option is seen as an important strategy for decreasing the adverse impacts of brain drain. Chinese academic diasporas have increasingly begun to create academic ties with China,...

In Situ Real-Time Chemiluminescence Imaging of Reactive Oxygen Species Formation from Cardiomyocytes (2009)

Yunbo Li, Haiou Shen, Hong Zhu, Michael A. Trush, Ming Jiang, Ge Wang

We have applied the highly sensitive chemiluminescence (CL) imaging technique to investigate the in situ ROS formation in cultured monolayers of rat H9c2 cardiomyocytes. Photon emission was detected...

Generating Structurally Complex Test Cases By Data Mutation: A Case Study Of Testing An Automated Modelling Tool (2009)

Shan, Lijun, Zhu, Hong

Generation of adequate test cases is difficult and expensive, especially for testing software systems whose input is structurally complex. This paper presents an approach called data mutation to...

Expression of VEGF-C Correlates with a Poor Prognosis Based on Analysis of Prognostic Factors in 73 Patients with Esophageal Squamous Cell Carcinomas (2009)

Liu, Pengfei, Chen, Weichang, Zhu, Hong, Liu, Bingtuan, Song, Shupin, Shen, Weidong, ...

Objective The purpose of this study was to specifically investigate the clinicopathological role of expression of vascular endothelial growth factor-C (VEGF-C) as well as the correlation with...

Approximating Spanning Tree with Weighted Inner Nodes (2008)

Jian Li, Haitao Wang, Rudolf Fleischer, Qi Ge, Hong Zhu

Abstract. We consider a problem coming from practical applications: finding a minimum spanning tree with both edge weights and inner node (non-leaf node) weights. This problem is NP-complete even in...

Incentive Compatible Mechanism Based on Linear Pricing Scheme for Single-Minded Auction ⋆ (2008)

Ning Chen, Hong Zhu

Abstract. In this paper, we study incentive compatible mechanism based on linear pricing scheme for single-minded auction, a restricted case of combinatorial auction, in which each buyer desires a...

A Dynamic Programming Approach of Finding an Optimal Broadcast Schedule in Minimizing Total Flow Time ∗ (2008)

Wun-tat Chan, Yong Zhang, Hong Zhu, Hong Shen

We study the problem of (off-line) broadcast scheduling in minimizing total flow time and propose a dynamic programming approach to compute an optimal broadcast schedule. Suppose the broadcast server...

High Resolution Live Streaming with the HYDRA Architecture (2008)

Roger Zimmermann, Moses Pawar, Dwipal A. Desai, Min Qin, Hong Zhu

Presently, digital continuous media (CM) are well established as an integral part of many applications. With High Definition (HD) displays becoming increasingly common and large network bandwidth...

doi:10.1093/comjnl/bxm043 Generating Structurally Complex Test Cases By Data Mutation: A Case Study Of Testing An Automated Modelling Tool (2008)

Lijun Shan, Hong Zhu

Generation of adequate test cases is difficult and expensive, especially for testing software systems whose input is structurally complex. This paper presents an approach called data mutation to...

1. Research Team HYDRA- High Resolution Live Streaming (2008)

Prof Alex, Er A. Sawchuk, Electrical Engineering, Graduate Students, Dwipal A. Desai, Kun Fu, ...

Presently, digital continuous media (CM) are well established as an integral part of many applications. With High Definition (HD) displays becoming increasingly common and large network bandwidth...

Traversing the Machining Graph (2008)

Danny Z. Chen, Rudolf Fleischer, Haitao Wang, Hong Zhu

Abstract. Zigzag pocket machining (or 2D-milling) plays an important role in the manufacturing industry. The objective is to minimize the number of tool retractions in the zigzag machining path for a...

Approximating the Maximum Sharing Problem (2008)

Amitabh Chaudhary, Danny Z. Chen, Rudolf Fleischer, Xiaobo S. Hu, Jian Li, Michael T. Niemier, ...

In the maximum sharing problem (MS), we want to compute a set of (non-simple) paths in an undirected bipartite graph covering as many nodes as possible of the first layer of the graph, with the...

Greedy Online Frequency Allocation in Cellular Networks (2008)

Wun-tat Chan, Deshi Ye, Yong Zhang, Hong Zhu

The online frequency allocation problem for cellular networks has been well studied in these years. Given a mobile telephone network, whose geographical coverage area is divided into cells, phone...

A 1-local 13/9-competitive Algorithm for Multicoloring Hexagonal Graphs (2008)

Yong Zhang, Hong Zhu

Abstract. In the frequency allocation problem, we are given a mobile telephone network, whose geographical coverage area is divided into cells, wherein phone calls are serviced by assigning...

A Novel Computational Based Method for Discovery of Sequence Motifs from Coexpressed Genes (2008)

Wengang Zhou, Hong Zhu, Guixia Liu, Yanxin Huang, Yan Wang, Dongbing Han, ...

The transcriptional regulation of gene expression is a key mechanism in the functioning of the cell. It is mostly affected through acting element binding to specific sequence motifs. In this paper,...

Traversing the Machining Graph (2008)

Danny Z. Chen, Rudolf Fleischer, Jian Li, Haitao Wang, Hong Zhu

Abstract. Zigzag pocket machining (or 2D-milling) plays an important role in the manufacturing industry. The objective is to minimize the number of tool retractions in the zigzag machining path for a...

Non-Metric Multicommodity and Multilevel Facility Location (2008)

Rudolf Fleischer, Jian Li, Shijun Tian, Hong Zhu

Abstract. We give logarithmic approximation algorithms for the nonmetric uncapacitated multicommodity and multilevel facility location problems. The former algorithms are optimal up to a constant...

Developing Formal Specifications of MAS in SLABS-- A Case Study of Evolutionary Multi-Agent Ecosystem (2008)

Hong Zhu

Abstract. The recent years has seen a rapid growth of research interests in agent-oriented software development methodology. A great amount of work has been reported in the literature on formal...

CAMLE 18/06/2003 CAMLE: A Caste-Centric Agent Modelling Language and Environment * (2008)

Lijun Shan, Hong Zhu

The necessity of a methodology for developing multi-agent systems (MAS) has been widely recognized due to the difficulties in analysis, specification, design, implementation and testing the...

Abstract (2008)

Jin-yi Cai, Hong Zhu

We briefly survey a number of important recent achievements in Theoretical Computer Science (TCS), especially Computational Complexity Theory. We will discuss the PCP Theorem, its implications to...

Zoned-RAID (2008)

Seon Ho Kim, Hong Zhu, Roger Zimmermann

The RAID (Redundant Array of Inexpensive Disks) system has been widely used in practical storage applications for better performance, cost effectiveness, and reliability. This study proposes a novel...

A Formal Approach to the Engineering of Emergence and its Recurrence (2008)

Martin R, Hong Zhu, A. Taleb-bendiab

Emergent behaviours are often characterised by the recurrent and recognizable events observable in a system’s macro-scale environment, which result from simple local interactions between system...

Tumorigenic activity and therapeutic inhibition of Rheb GTPase (2008)

Mavrakis, Konstantinos J., Zhu, Hong, Silva, Ricardo L.A., Mills, John R., Teruya-Feldstein, Julie, Lowe, Scott W., ...

The AKT–mTOR pathway harbors several known and putative oncogenes and tumor suppressors. In a phenotypic screen for lymphomagenesis, we tested candidate genes acting upstream of and downstream from...

In Situ Real-Time Chemiluminescence Imaging of Reactive Oxygen Species Formation from Cardiomyocytes (2008)

Yunbo Li, Haiou Shen, Hong Zhu, Michael A. Trush, Ming Jiang, Ge Wang

We have applied the highly sensitive chemiluminescence (CL) imaging technique to investigate the in situ ROS formation in cultured monolayers of rat H9c2 cardiomyocytes. Photon emission was detected...

Automating Scenario-Driven RE 2/7/2000 Automating Scenario-Driven Structured Requirements Engineering (2007)

Hong Zhu, Lingzi Jin

Scenario analysis has been widely perceived to be able to play two important roles in requirement engineering. Firstly, it is a vehicle of separating concerns in the elicitation of users '...

Towards Agent-Oriented Quality Management of Information Systems (2007)

Hong Zhu, Sue Greenwood, Qingning Huo, Yanlong Zhang

The emergence of agent-oriented information systems imposes a great challenge to the current theories and methods of software quality management. The difficulties in the development of quality...

Developing Formal Specifications of MAS in SLABS-- A Case Study of Evolutionary Multi-Agent Ecosystem (2007)

Hong Zhu

Abstract. The recent years has seen a rapid growth of research interests in agent-oriented software development methodology. A great amount of work has been reported in the literature on formal...

1: Design and Evaluation of a Streaming Media (2007)

Roger Zimmermann, Kun Fu, Cyrus Shahabi, Didi Yao, Hong Zhu

Abstract. We describe and evaluate the implementation of a streaming media system called Yima, which consists of a scalable continuous media server and client components. We report on the real-life...

New Classes of Interconnection Topology Structures and Their Properties (2007)

Hong Zhu, Zheng Sun

In the first part of this paper, three generalizations of arrangement graph A n;k of [1], namely B n;k, C n;k and D n;k, are introduced. We prove that all the three classes of graphs are vertex...

The Advantage of PET and CT Integration in Examination of Lung Tumors (2007)

Guangming Lu, Zhongqiu Wang, Hong Zhu, Linfeng Chang, Yingxin Chen, Jiang Wu, ...

Purpose. To evaluate the diagnosis value of integrated positron emission tomography and computed tomography (PET/CT) with lung masses, this study emphasized the correlation between tumor size and...

Normal acceleration characteristics of the leading vehicle in a queue at signalized intersections on arterial streets / (2007)

Zhu, Hong.

Normal acceleration characteristics of passenger cars provide valuable information for various aspects of transportation engineering, including use in the geometric designs of intersections, freeway...

Gutmann, H.-M. (2007)

Mark P. Wachowiak, J. Lindström, Hong Zhu

Parallel Newton-Krylov methods for PDE-constrained optimization

The Advantage of PET and CT Integration in Examination of Lung Tumors (2007)

Guangming Lu, Zhongqiu Wang, Hong Zhu, Linfeng Chang, Yingxin Chen, Jiang Wu, ...

Purpose. To evaluate the diagnosis value of integrated positron emission tomography and computed tomography (PET/CT) with lung masses, this study emphasized the correlation between tumor size and...

Dissecting eIF4E action in tumorigenesis (2007)

Wendel, Hans-Guido, Silva, Ricardo L.A., Malina, Abba, Mills, John R., Zhu, Hong, Ueda, Takeshi, ...

Genetically engineered mouse models are powerful tools for studying cancer genes and validating targets for cancer therapy. We previously used a mouse lymphoma model to demonstrate that the...

Frequency Allocation Problem for Linear Cellular Networks (2006)

Deshi Ye, Yong Zhang, Hong Zhu

Abstract. We study the online frequency allocation problem for wireless linear (highway) cellular networks, where the geographical coverage area is divided into cells aligned in a line. Calls arrive...

On approximating the maximum simple sharing problem (2006)

Danny Z. Chen, Rudolf Fleischer, Jian Li, Zhiyi Xie, Hong Zhu

Abstract. In the maximum simple sharing problem (MSS), we want to compute a set of node-disjoint simple paths in an undirected bipartite graph covering as many nodes as possible of one layer of the...

On approximating the maximum simple sharing problem (2006)

Danny Z. Chen, Rudolf Fleischer, Zhiyi Xie, Hong Zhu

Abstract. In the maximum simple sharing problem (MSS), wewantto compute a set of node-disjoint simple paths in an undirected bipartite graph covering as many nodes as possible of one layer of the...

Formal Reasoning about Emergent Behaviour (2005)

Hong Zhu

Abstract. Emergent behaviour (EB) is a common phenomenon in multi-agent systems (MAS) where autonomous agents perform certain actions with only limited access to local information and make decisions...

broadcast schedule in minimizing total flow time (2005)

Wun-tat Chan, Yong Zhang, Hong Zhu, Hong Shen, ...

A dynamic programming approach of finding an optimal

Efficient Algorithms for Finding A Longest Common Increasing Subsequence (2005)

Wun-tat Chan, Yong Zhang, Deshi Ye, Hong Zhu

We study the problem of finding a longest common increasing subsequence (LCIS) of multiple sequences of numbers. The LCIS problem is a fundamental issue in various application areas, including the...

Quantum m-out-of-n Oblivious Transfer (2003)

Chen, Zhide, Zhu, Hong

In the m-out-of-n oblivious transfer (OT) model, one party Alice sends n bits to another party Bob, Bob can get only m bits from the n bits. However, Alice cannot know which m bits Bob received....

H.: Resettable Zero-Knowledge in the Weak PublicKey Model (2003)

Yunlei Zhao, Xiaotie Deng, C. H. Lee, Hong Zhu

Abstract. A new public-key model for resettable zero-knowledge (rZK) protocols, which is an extension and generalization of the upperbounded public-key (UPK) model introduced by Micali and Reyzin...

In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system (2003)

Wu, Jianxin, Zhu, Bei-Bei, Yu, Jin, Zhu, Hong, Qiu, Lu, Kindy, Mark S., ...

Benzo[c]phenanthrene dihydrodiol epoxide (B[c] PhDE) is well known as an important environmental chemical carcinogen that preferentially modifies DNA in adenine residues. However,...

A digital field trip to colonial Williamsburg / (2002)

Zhu, Hong.

"College of Mass Communication and Media Arts."

Methyl Parathion Masks Withdrawal from Physical Dependence on Morphine (2002)

Hong Zhu, Ing K. Ho, Robert E. Kramer, Rodney C. Baker, Robin W. Rockhold

Abstract: The cholinergic system has been proposed to participate in the development of dependence on opioids. The present study examined effects of dermal pretreatment with methyl parathion (MP), an...

Global optimization of slider air bearing design / (2002)

Zhu, Hong.

Thesis (Ph.D. in Engineering-Mechanical Engineering)--University of California, Berkeley, Fall 2002.

A theory of testing high-level Petri nets (2000)

Hong Zhu, Xudong He

A high-level Petri net can be viewed as an abstract concurrent program and thus can be tested. In this paper, we present a theory of testing high-level Petri nets by adapting some of our general...

Evaluation of load transfer behavior of bored piles in residual soil incorporating construction effect / (2000)

Zhu, Hong.

Thesis (Ph.D.)--Nanyang Technological University, School of Civil and Structural Engineering, 2000.

A theory of behaviour observation in software testing (1999)

Hong Zhu, Xudong He

Software testing is a process in which a software system's dynamic behaviours are observed and analysed so that the system's properties can be inferred from the information revealed by test...

Processable Polymers and Copolymers of 3-Alkylthiophenes and Their Blends. (1998)

Pomerantz, Martin, Tseng, John J., Zhu, Hong, Sproull, Steven J., Reynolds, John R.

Poly(3-alkylthiophenes) have been prepared using anhydrous FeCL3 while dry air was bubbled through the reaction mixture. Molecular weight studies via GPC, using polystyrene standards in conjunction...

Corrosion and Oxidation Behaviors of Intermetallic Compound Ni3Al(0.1B) Modified by Ion Beam Technology. (1998)

Liu, Xianghuai, Wang, X., Yang, Genging, Jiang, Binyao, Zhu, Hong

The corrosion and oxidation behavior of Ni3Al(0.1B) treated with different ion beam techniques has been systematically investigated. The results revealed that ion implantation, ion beam mixing and...

Software unit test coverage and adequacy (1997)

Hong Zhu

Objective measurement of test quality is one of the key issues in software testing. It has been a major research focus for the last two decades. Many test criteria have been proposed and studied for...

The nuclear SUV3-1 mutation affects a variety of post-transcriptional processes in yeast mitochondria (1990)

Conrad-Webb, Heather, Perlman, Philip S., Zhu, Hong, Butow, Ronald A.

The SUV3-1 mutation was isolated earlier as a suppressor of a deletion of a conserved RNA processing site (dodecamer) near the 3′ end of the var1 gene. Previous studies Indicate that the suppressor...

Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury

Dubal, Dena B., Zhu, Hong, Yu, Jin, Rau, Shane W., Shughrue, Paul J., Merchenthaler, Istvan, ...

Estradiol protects against brain injury, neurodegeneration, and cognitive decline. Our previous work demonstrates that physiological levels of estradiol protect against stroke injury and that this...

Characterization of an Atrazine-Degrading Pseudaminobacter sp. Isolated from Canadian and French Agricultural Soils

Topp, Edward, Zhu, Hong, Nour, Sarah M., Houot, Sabine, Lewis, Melanie, Cuppels, Diane

Atrazine, a herbicide widely used in corn production, is a frequently detected groundwater contaminant. Fourteen bacterial strains able to use this herbicide as a sole source of nitrogen were...

Characterization of S-Triazine Herbicide Metabolism by a Nocardioides sp. Isolated from Agricultural Soils

Topp, Edward, Mulbry, Walter M., Zhu, Hong, Nour, Sarah M., Cuppels, Diane

Atrazine, a herbicide widely used in corn production, is a frequently detected groundwater contaminant. Nine gram-positive bacterial strains able to use this herbicide as a sole source of nitrogen...

Bacteria Associated with Cysts of the Soybean Cyst Nematode (Heterodera glycines)

Nour, Sarah M., Lawrence, John R., Zhu, Hong, Swerhone, George D. W., Welsh, Martha, Welacky, Tom W., ...

The soybean cyst nematode (SCN), Heterodera glycines, causes economically significant damage to soybeans (Glycine max) in many parts of the world. The cysts of this nematode can remain quiescent in...

Purification and Characterization of an Extracellular Acid Proteinase from the Ectomycorrhizal Fungus Hebeloma crustuliniforme

Zhu, Hong, Guo, Da-Cheng, Dancik, Bruce P.

Hebeloma crustuliniforme produced an extracellular acid proteinase in a liquid medium containing bovine serum albumin as the sole nitrogen source. The proteinase was purified 26-fold with 20%...

The K1 Toxin of Saccharomyces cerevisiae Kills Spheroplasts of Many Yeast Species

Zhu, Hong, Bussey, Howard

The Saccharomyces cerevisiae K1 toxin killed spheroplasts from the genera Candida, Kluyveromyces, and Schwanniomyces. Cells of these organisms were toxin insensitive. The toxin bound poorly to...

In vitro and in vivo modulations of benzo[c]phenanthrene–DNA adducts by DNA mismatch repair system

Wu, Jianxin, Zhu, Bei-Bei, Yu, Jin, Zhu, Hong, Qiu, Lu, Kindy, Mark S., ...

Benzo[c]phenanthrene dihydrodiol epoxide (B[c] PhDE) is well known as an important environmental chemical carcinogen that preferentially modifies DNA in adenine residues. However, the molecular...

The Nuclear Hormone Receptor Coactivator NRC Is a Pleiotropic Modulator Affecting Growth, Development, Apoptosis, Reproduction, and Wound Repair

Mahajan, Muktar A., Das, Sharmistha, Zhu, Hong, Tomic-Canic, Marjana, Samuels, Herbert H.

Nuclear hormone receptor coregulator (NRC) is a 2,063-amino-acid coregulator of nuclear hormone receptors and other transcription factors (e.g., c-Fos, c-Jun, and NF-κB). We and others have...

Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury

Dubal, Dena B., Zhu, Hong, Yu, Jin, Rau, Shane W., Shughrue, Paul J., Merchenthaler, Istvan, ...

Estradiol protects against brain injury, neurodegeneration, and cognitive decline. Our previous work demonstrates that physiological levels of estradiol protect against stroke injury and that this...

Characterization of an Atrazine-Degrading Pseudaminobacter sp. Isolated from Canadian and French Agricultural Soils

Topp, Edward, Zhu, Hong, Nour, Sarah M., Houot, Sabine, Lewis, Melanie, Cuppels, Diane

Atrazine, a herbicide widely used in corn production, is a frequently detected groundwater contaminant. Fourteen bacterial strains able to use this herbicide as a sole source of nitrogen were...

Characterization of S-Triazine Herbicide Metabolism by a Nocardioides sp. Isolated from Agricultural Soils

Topp, Edward, Mulbry, Walter M., Zhu, Hong, Nour, Sarah M., Cuppels, Diane

Atrazine, a herbicide widely used in corn production, is a frequently detected groundwater contaminant. Nine gram-positive bacterial strains able to use this herbicide as a sole source of nitrogen...

Bacteria Associated with Cysts of the Soybean Cyst Nematode (Heterodera glycines)

Nour, Sarah M., Lawrence, John R., Zhu, Hong, Swerhone, George D. W., Welsh, Martha, Welacky, Tom W., ...

The soybean cyst nematode (SCN), Heterodera glycines, causes economically significant damage to soybeans (Glycine max) in many parts of the world. The cysts of this nematode can remain quiescent in...

Purification and Characterization of an Extracellular Acid Proteinase from the Ectomycorrhizal Fungus Hebeloma crustuliniforme

Zhu, Hong, Guo, Da-Cheng, Dancik, Bruce P.

Hebeloma crustuliniforme produced an extracellular acid proteinase in a liquid medium containing bovine serum albumin as the sole nitrogen source. The proteinase was purified 26-fold with 20%...

The K1 Toxin of Saccharomyces cerevisiae Kills Spheroplasts of Many Yeast Species

Zhu, Hong, Bussey, Howard

The Saccharomyces cerevisiae K1 toxin killed spheroplasts from the genera Candida, Kluyveromyces, and Schwanniomyces. Cells of these organisms were toxin insensitive. The toxin bound poorly to...

In vitro and in vivo modulations of benzo[c]phenanthrene–DNA adducts by DNA mismatch repair system

Wu, Jianxin, Zhu, Bei-Bei, Yu, Jin, Zhu, Hong, Qiu, Lu, Kindy, Mark S., ...

Benzo[c]phenanthrene dihydrodiol epoxide (B[c] PhDE) is well known as an important environmental chemical carcinogen that preferentially modifies DNA in adenine residues. However, the molecular...

The Nuclear Hormone Receptor Coactivator NRC Is a Pleiotropic Modulator Affecting Growth, Development, Apoptosis, Reproduction, and Wound Repair

Mahajan, Muktar A., Das, Sharmistha, Zhu, Hong, Tomic-Canic, Marjana, Samuels, Herbert H.

Nuclear hormone receptor coregulator (NRC) is a 2,063-amino-acid coregulator of nuclear hormone receptors and other transcription factors (e.g., c-Fos, c-Jun, and NF-κB). We and others have...

The Advantage of PET and CT Integration in Examination of Lung Tumors

Lu, Guangming, Wang, Zhongqiu, Zhu, Hong, Chang, Linfeng, Chen, Yingxin, Wu, Jiang, ...

Purpose. To evaluate the diagnosis value of integrated positron emission tomography and computed tomography (PET/CT) with lung masses, this study emphasized the correlation between tumor size and...

Small molecule regulators of autophagy identified by an image-based high-throughput screen

Zhang, Lihong, Yu, Jia, Pan, Heling, Hu, Ping, Hao, Yan, Cai, Wenqing, ...

Autophagy is a lysosome-dependent cellular catabolic mechanism mediating the turnover of intracellular organelles and long-lived proteins. Reduction of autophagy activity has been shown to lead to...

Dissecting eIF4E action in tumorigenesis

Wendel, Hans-Guido, Silva, Ricardo L.A., Malina, Abba, Mills, John R., Zhu, Hong, Ueda, Takeshi, ...

Genetically engineered mouse models are powerful tools for studying cancer genes and validating targets for cancer therapy. We previously used a mouse lymphoma model to demonstrate that the...

China's implicit demand for foreign reserves: neutralization and the rise in reserves

Zhuo Tan, Shenggang Yang, Hong Zhu

We estimate China's demand for foreign reserves from 1994:1 to 2007:4. Using a monetary model for China's reserve demand, we take into account the People's Bank of China's systematic neutralization...

Mitochondrial DNA Evidence for a Diversified Origin of Workers Building Mausoleum for First Emperor of China

Xu, Zhi, Zhang, Fan, Xu, Bosong, Tan, Jingze, Li, Shilin, Li, Chunxiang, ...

Variant studies on ancient DNA have attempted to reveal individual origin. Here, based on cloning sequencing and polymerase chain reaction-restriction fragment length polymorphisms, we analyzed...

Neprilysin: An Enzyme Candidate to Slow the Progression of Alzheimer’s Disease

El-Amouri, Salim S., Zhu, Hong, Yu, Jin, Marr, Robert, Verma, Inder M., Kindy, Mark S.

It is well established that the extracellular deposition of amyloid β (Aβ) peptide plays a central role in the development of Alzheimer’s disease (AD). Therefore, either preventing the...

Castration Had No Effect on Decreased Expression of the Neural Cell Adhesion Molecule in the Prefrontal Cortex of Rats Subjected to Chronic Mild Stress

Huang, Qian, Liu, Hui, Zhu, Hong, Zhou, Jiang-Ning

The effect of chronic mild stress on protein levels of the neural cell adhesion molecule (NCAM) were evaluated in the prefrontal cortex and hippocampus of rat brain. Decreased NCAM protein expression...

Number-Based Visual Generalisation in the Honeybee

Gross, Hans J., Pahl, Mario, Si, Aung, Zhu, Hong, Tautz, Jürgen, Zhang, Shaowu

Although the numerical abilities of many vertebrate species have been investigated in the scientific literature, there are few convincing accounts of invertebrate numerical competence. Honeybees,...

Tumorigenic activity and therapeutic inhibition of Rheb GTPase

Mavrakis, Konstantinos J., Zhu, Hong, Silva, Ricardo L.A., Mills, John R., Teruya-Feldstein, Julie, Lowe, Scott W., ...

The AKT–mTOR pathway harbors several known and putative oncogenes and tumor suppressors. In a phenotypic screen for lymphomagenesis, we tested candidate genes acting upstream of and downstream from...

In Situ Real-Time Chemiluminescence Imaging of Reactive Oxygen Species Formation from Cardiomyocytes

Li, Yunbo, Shen, Haiou, Zhu, Hong, Trush, Michael A., Jiang, Ming, Wang, Ge

We have applied the highly sensitive chemiluminescence (CL) imaging technique to investigate the in situ ROS formation in cultured monolayers of rat H9c2 cardiomyocytes. Photon emission was detected...

Restoration of Mature Etiolated Cucumber Hypocotyl Cell Wall Susceptibility to Expansin by Pretreatment with Fungal Pectinases and EGTA in Vitro1

Zhao, Qingxin, Yuan, Sheng, Wang, Xin, Zhang, Yuling, Zhu, Hong, Lu, Changmei

Mature plant cell walls lose their ability to expand and become unresponsive to expansin. This phenomenon is believed to be due to cross-linking of hemicellulose, pectin, or phenolic groups in the...

Microbial Conversion of Glycerol to 1,3-Propanediol by an Engineered Strain of Escherichia coli▿

Tang, Xueming, Tan, Yongsong, Zhu, Hong, Zhao, Kai, Shen, Wei

In an effort to improve industrial production of 1,3-propanediol (1,3-PD), we engineered a novel polycistronic operon under the control of the temperature-sensitive lambda phage PLPR promoter...

Parcs Is a Dual Regulator of Cell Proliferation and Apaf-1 Function*

Sanchez-Olea, Roberto, Ortiz, Sara, Barreto, Odmara, Yang, Qing, Xu, Chi-jie, Zhu, Hong, ...

Here we identify a novel protein, named Parcs for pro-apoptotic protein required for cell survival, that is involved in both cell cycle progression and apoptosis. Parcs interacted with Apaf-1 by...

Naphthalimides Induce G2 Arrest Through the ATM-Activated Chk2-Executed Pathway in HCT116 Cells1

Zhu, Hong, Miao, Ze-Hong, Huang, Min, Feng, Jian-Ming, Zhang, Zhi-Xiang, Lu, Jin-Jian, ...

Naphthalimides, particularly amonafide and 2-(2-dimethylamino)-6-thia-2-aza-benzo[def]chrysene-1,3-diones (R16), have been identified to possess anticancer activities and to induce G2-M arrest...

A Novel Small Molecule Regulator of Guanine Nucleotide Exchange Activity of the ADP-ribosylation Factor and Golgi Membrane Trafficking*S⃞

Pan, Heling, Yu, Jia, Zhang, Lihong, Carpenter, Anne, Zhu, Hong, Li, Li, ...

An image-based phenotypic screen was developed to identify small molecule regulators of intracellular traffic. Using this screen we found that AG1478, a previously known inhibitor of epidermal growth...