Howard R. Morris

Publication List Details

Period

2001 - 2007

Number

37

Co-Authors

Identification and structural characterisation of a partially arabinosylated lipoarabinomannan variant isolated from a Corynebacterium glutamicum ubiAmutant (2007)

Tatituri, Raju Venkata Veera, Alderwick, Luke J, Mishra, Arun K., Nigou, Jerome, Gilleron, Martine, Krumbach, Karin, ...

Arabinan polysaccharide side-chains are present in both Mycobacterium tuberculosis and Corynebacterium glutamicum in the heteropolysaccharide arabinogalactan (AG), and in M. tuberculosis in the...

Identification and structural characterisation of a partially arabinosylated lipoarabinomannan variant isolated from a Corynebacterium glutamicum ubiAmutant (2007)

Tatituri, Raju Venkata Veera, Alderwick, Luke J, Mishra, Arun K., Nigou, Jerome, Gilleron, Martine, Krumbach, Karin, ...

Arabinan polysaccharide side-chains are present in both Mycobacterium tuberculosis and Corynebacterium glutamicum in the heteropolysaccharide arabinogalactan (AG), and in M. tuberculosis in the...

Identification of a capsular polysaccharide from moraxella bovis (2005)

Wilson, Jenny, Hitchen, Paul G, Frank, Martin, Peak, Ian, Collins, Patrick, Morris, Howard R., ...

The bacterium Moraxella bovis is the causative agent of an economically important disease of cattle: Infectious Bovine Keratoconjunctivitis (IBK), otherwise known as pinkeye. Little is known...

Identification of a capsular polysaccharide from moraxella bovis (2005)

Wilson, Jenny, Hitchen, Paul G, Frank, Martin, Peak, Ian, Collins, Patrick, Morris, Howard R., ...

The bacterium Moraxella bovis is the causative agent of an economically important disease of cattle: Infectious Bovine Keratoconjunctivitis (IBK), otherwise known as pinkeye. Little is known...

Identification of a capsular polysaccharide from moraxella bovis (2005)

Wilson, Jenny, Hitchen, Paul G, Frank, Martin, Peak, Ian, Collins, Patrick, Morris, Howard R., ...

The bacterium Moraxella bovis is the causative agent of an economically important disease of cattle: Infectious Bovine Keratoconjunctivitis (IBK), otherwise known as pinkeye. Little is known...

Differences in Glycosylation and Sperm-Egg Binding Inhibition of Pregnancy-Related Glycodelin1 (2003)

Hannu Koistinen, Richard L. Easton, Sara Chalabi, Mervi Halttunen, Anne Dell, ...

Glycodelin is a glycoprotein produced in many glands, particularly those of reproductive tissues. It appears as different glycoforms in amniotic fluid (glycodelin-A) and seminal plasma...

The contribution of tandem repeat number to the O-glycosylation of mucins (2003)

Silverman, Howard Scott, Sutton-Smith, Mark, McDermott, Kimberley, Heal, Paul, Leir, Shih-Hsing, Morris, Howard R., ...

The serine- and threonine-rich tandem repeat (TR) units that make up the characteristic feature of mucin glycoproteins are often polymorphic with substantial genetic variation in TR number. The...

In vivo glycosylation of mucin tandem repeats (2001)

Silverman, Howard S., Parry, Simon, Sutton-Smith, Mark, Burdick, Michael D., McDermott, Kimberly, Reid, Colm J., ...

The biochemical and biophysical properties of mucins are largely determined by extensive O-glycosylation of serine- and threonine-rich tandem repeat (TR) domains. In a number of human diseases...

Genetic remodeling of protein glycosylation in vivo induces autoimmune disease

Chui, Daniel, Sellakumar, Gayathri, Green, Ryan S., Sutton-Smith, Mark, McQuistan, Tammie, Marek, Kurt W., ...

Autoimmune diseases are among the most prevalent of afflictions, yet the genetic factors responsible are largely undefined. Protein glycosylation in the Golgi apparatus produces structural variation...

Identification of Major Outer Surface Proteins of Streptococcus agalactiae

Hughes, Martin J. G., Moore, Joanne C., Lane, Jonathan D., Wilson, Rebecca, Pribul, Philippa K., Younes, Zabin N., ...

To identify the major outer surface proteins of Streptococcus agalactiae (group B streptococcus), a proteomic analysis was undertaken. An extract of the outer surface proteins was separated by...

Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans

Dell, Anne, Chalabi, Sara, Easton, Richard L., Haslam, Stuart M., Sutton-Smith, Mark, Patankar, Manish S., ...

Murine sperm initiate fertilization by binding to the outer covering of the egg known as the murine zona pellucida (mZP). This binding is thought to require the interaction of O-glycans linked to a...

Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili

Hegge, Finn Terje, Hitchen, Paul G., Aas, Finn Erik, Kristiansen, Heidi, Løvold, Cecilia, Egge-Jacobsen, Wolfgang, ...

Several major bacterial pathogens and related commensal species colonizing the human mucosa express phosphocholine (PC) at their cell surfaces. PC appears to impact host–microbe biology by serving...

Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli

Feldman, Mario F., Wacker, Michael, Hernandez, Marcela, Hitchen, Paul G., Marolda, Cristina L., Kowarik, Michael, ...

Campylobacter jejuni has a general N-linked protein glycosylation system that can be functionally transferred to Escherichia coli. In this study, we engineered E. coli cells in a way that two...

Collagen cross-links. A mass-spectrometric and 1H- and 13C-nuclear-magnetic-resonance study

Hunt, Eric, Morris, Howard R.

1. The structure of a tetrafunctional cross-link (compound C) isolated from borohydride-reduced cow skin collagen has been determined by the combined use of mass spectrometry and 1H and 13C n.m.r....

Dihydrofolate reductase: low-resolution mass-spectrometric analysis of an elastase digest as a sequencing tool (Short Communication)

Morris, Howard R., Batley, Karen E., Harding, Nigel G. L., Bjur, Richard A., Dann, John G., King, Rodney W.

An elastase digest of a protein of unknown structure, dihydrofolate reductase, was studied by mass spectrometry. This soluble digest contained a large number of small peptides in different yields,...

A mass-spectrometric sequence study of the enzyme ribitol dehydrogenase from Klebsiella aerogenes

Morris, Howard R., Williams, Dudley H., Midwinter, Graeme G., Hartley, Brian S.

The first detailed results of the application of a low-resolution mixture analysis approach to the sequence analysis of an enzyme, ribitol dehydrogenase, are given. Examples of the interpretation of...

Determination of the sequences of protein-derived peptides and peptide mixtures by mass spectrometry

Morris, Howard R., Williams, Dudley H., Ambler, Richard P.

Micro-quantities of protein-derived peptides have been converted into N-acetylated permethyl derivatives, and their sequences determined by low-resolution mass spectrometry without prior knowledge of...

Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis.

Kremer, Laurent, Gurcha, Sudagar S, Bifani, Pablo, Hitchen, Paul G, Baulard, Alain, Morris, Howard R, ...

Phosphatidyl-myo-inositol mannosides (PIMs), lipomannan (LM) and lipoarabinomannan (LAM) are an important class of bacterial factors termed modulins that are found in tuberculosis and leprosy....

Essential and mutually compensatory roles of α-mannosidase II and α-mannosidase IIx in N-glycan processing in vivo in mice

Akama, Tomoya O., Nakagawa, Hiroaki, Wong, Nyet Kui, Sutton-Smith, Mark, Dell, Anne, Morris, Howard R., ...

Many proteins synthesized through the secretory pathway receive posttranslational modifications, including N-glycosylation. α-Mannosidase II (MII) is a key enzyme converting precursor...

Genetic remodeling of protein glycosylation in vivo induces autoimmune disease

Chui, Daniel, Sellakumar, Gayathri, Green, Ryan S., Sutton-Smith, Mark, McQuistan, Tammie, Marek, Kurt W., ...

Autoimmune diseases are among the most prevalent of afflictions, yet the genetic factors responsible are largely undefined. Protein glycosylation in the Golgi apparatus produces structural variation...

Identification of Major Outer Surface Proteins of Streptococcus agalactiae

Hughes, Martin J. G., Moore, Joanne C., Lane, Jonathan D., Wilson, Rebecca, Pribul, Philippa K., Younes, Zabin N., ...

To identify the major outer surface proteins of Streptococcus agalactiae (group B streptococcus), a proteomic analysis was undertaken. An extract of the outer surface proteins was separated by...

Murine and human zona pellucida 3 derived from mouse eggs express identical O-glycans

Dell, Anne, Chalabi, Sara, Easton, Richard L., Haslam, Stuart M., Sutton-Smith, Mark, Patankar, Manish S., ...

Murine sperm initiate fertilization by binding to the outer covering of the egg known as the murine zona pellucida (mZP). This binding is thought to require the interaction of O-glycans linked to a...

Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili

Hegge, Finn Terje, Hitchen, Paul G., Aas, Finn Erik, Kristiansen, Heidi, Løvold, Cecilia, Egge-Jacobsen, Wolfgang, ...

Several major bacterial pathogens and related commensal species colonizing the human mucosa express phosphocholine (PC) at their cell surfaces. PC appears to impact host–microbe biology by serving...

Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli

Feldman, Mario F., Wacker, Michael, Hernandez, Marcela, Hitchen, Paul G., Marolda, Cristina L., Kowarik, Michael, ...

Campylobacter jejuni has a general N-linked protein glycosylation system that can be functionally transferred to Escherichia coli. In this study, we engineered E. coli cells in a way that two...

Collagen cross-links. A mass-spectrometric and 1H- and 13C-nuclear-magnetic-resonance study

Hunt, Eric, Morris, Howard R.

1. The structure of a tetrafunctional cross-link (compound C) isolated from borohydride-reduced cow skin collagen has been determined by the combined use of mass spectrometry and 1H and 13C n.m.r....

Dihydrofolate reductase: low-resolution mass-spectrometric analysis of an elastase digest as a sequencing tool (Short Communication)

Morris, Howard R., Batley, Karen E., Harding, Nigel G. L., Bjur, Richard A., Dann, John G., King, Rodney W.

An elastase digest of a protein of unknown structure, dihydrofolate reductase, was studied by mass spectrometry. This soluble digest contained a large number of small peptides in different yields,...

A mass-spectrometric sequence study of the enzyme ribitol dehydrogenase from Klebsiella aerogenes

Morris, Howard R., Williams, Dudley H., Midwinter, Graeme G., Hartley, Brian S.

The first detailed results of the application of a low-resolution mixture analysis approach to the sequence analysis of an enzyme, ribitol dehydrogenase, are given. Examples of the interpretation of...

Determination of the sequences of protein-derived peptides and peptide mixtures by mass spectrometry

Morris, Howard R., Williams, Dudley H., Ambler, Richard P.

Micro-quantities of protein-derived peptides have been converted into N-acetylated permethyl derivatives, and their sequences determined by low-resolution mass spectrometry without prior knowledge of...

Characterization of a putative alpha-mannosyltransferase involved in phosphatidylinositol trimannoside biosynthesis in Mycobacterium tuberculosis.

Kremer, Laurent, Gurcha, Sudagar S, Bifani, Pablo, Hitchen, Paul G, Baulard, Alain, Morris, Howard R, ...

Phosphatidyl-myo-inositol mannosides (PIMs), lipomannan (LM) and lipoarabinomannan (LAM) are an important class of bacterial factors termed modulins that are found in tuberculosis and leprosy....

Essential and mutually compensatory roles of α-mannosidase II and α-mannosidase IIx in N-glycan processing in vivo in mice

Akama, Tomoya O., Nakagawa, Hiroaki, Wong, Nyet Kui, Sutton-Smith, Mark, Dell, Anne, Morris, Howard R., ...

Many proteins synthesized through the secretory pathway receive posttranslational modifications, including N-glycosylation. α-Mannosidase II (MII) is a key enzyme converting precursor...

Structural characterization and functional properties of a novel lipomannan variant isolated from a Corynebacterium glutamicum pimB′ mutant

Mishra, Arun K., Klein, Christina, Gurcha, Sudagar S., Alderwick, Luke J., Babu, Ponnusamy, Hitchen, Paul G., ...

The genus Corynebacterium is part of the phylogenetic group nocardioform actinomycetes, which also includes the genus Mycobacterium. Members of this phylogenetic group have a characteristic cell...

Identification of AglE, a Second Glycosyltransferase Involved in N Glycosylation of the Haloferax volcanii S-Layer Glycoprotein▿

Abu-Qarn, Mehtap, Giordano, Assunta, Battaglia, Francesca, Trauner, Andrej, Hitchen, Paul G., Morris, Howard R., ...

Archaea, like Eukarya and Bacteria, are able to N glycosylate select protein targets. However, in contrast to relatively advanced understanding of the eukaryal N glycosylation process and the...

A Filovirus-Unique Region of Ebola Virus Nucleoprotein Confers Aberrant Migration and Mediates Its Incorporation into Virions▿

Shi, Wei, Huang, Yue, Sutton-Smith, Mark, Tissot, Berangere, Panico, Maria, Morris, Howard R., ...

The Ebola virus nucleoprotein (NP) is an essential component of the nucleocapsid, required for filovirus particle formation and replication. Together with virion protein 35 (VP35) and VP24, this gene...