Hua Su

Publication List Details

Period

1998 - 2009

Number

67

Co-Authors

Sesquiterpenes from Laurencia similis (2009)

Hua Su, Da-Yong Shi, Jing Li, Shu-Ju Guo, Li-Li Li, Zhao-Hui Yuan, ...

One new sesquiterpene, (4E)-1-bromo-5-[(1'S*,3'R*)-3'-bromo-2',2'-dimethyl-6'-methylenecyclohexyl]-3-methylpent-4-ene-2,3-diol (1), and fifteen known sesquiterpenes, isopalisol (2), luzonensol (3),...

Solutions for m-Point BVP with Sign Changing Nonlinearity (2009)

Hua Su

We study the existence of positive solutions for the following nonlinear m-point boundary value problem for an increasing homeomorphism and homomorphism with sign changing nonlinearity:...

Positive solutions for nonlinear difference equations involving the p-Laplacian with sign changing nonlinearity (2009)

Yanbin Sang, Hua Su

By means of fixed point index, we establish sufficient conditions for the existence of positive solutions to p-Laplacian difference equations. In particular, the nonlinear term is allowed to change...

Solutions for m-Point BVP with Sign Changing Nonlinearity (2009)

Hua Su

We study the existence of positive solutions for the following nonlinear m-point boundary value problem for an increasing homeomorphism and homomorphism with sign changing nonlinearity:...

Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity (2009)

Su, Hua, Gunter, Jennifer H., De Vries, Melissa, Connor, Tim, Wanyonyi, Stephen, Newell, Felicity S., ...

We previously described a putative role for inosine monophosphate dehydrogenase (IMPDH), a rate-limiting enzyme in de novo guanine nucleotide biosynthesis, in lipid accumulation. Here we present data...

Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity (2009)

Su, Hua, Gunter, Jennifer H., De Vries, Melissa, Connor, Tim, Wanyonyi, Stephen, Newell, Felicity S., ...

We previously described a putative role for inosine monophosphate dehydrogenase (IMPDH), a rate-limiting enzyme in de novo guanine nucleotide biosynthesis, in lipid accumulation. Here we present data...

MicroRNA-encoding long non-coding RNAs (2008)

He, Shunmin, Su, Hua, Liu, Changning, Skogerbø, Geir, He, Housheng, He, Dandan, ...

Abstract Background Recent analysis of the mouse transcriptional data has revealed the existence of ~34,000 messenger-like non-coding RNAs (ml-ncRNAs). Whereas the functional properties of these...

Chapter 18 GENE PATHWAY TEXT MINING AND VISUALIZATION (2008)

Daniel M. Mcdonald, Hua Su, Jennifer Xu, Chun-ju Tseng, Gondy Leroy

Automatically extracting gene-pathway relations from medical research texts gives researchers access to the latest findings in a structured format. Such relations must be precise to be useful. We...

LINKING ONTOLOGICAL RESOURCES USING AGGREGATABLE SUBSTANCE IDENTIFIERS TO ORGANIZE EXTRACTED RELATIONS (2008)

B. Marshall, H. Su, D. Mcdonald, H. Chen, Byron Marshall, Hua Su, ...

Systems that extract biological regulatory pathway relations from free-text sources are intended to help researchers leverage vast and growing collections of research literature. Several systems to...

Chapter 21 JOINT LEARNING USING MULTIPLE TYPES OF DATA AND KNOWLEDGE (2008)

Zan Huang, Hua Su, Hsinchun Chen

Abstract: This chapter discusses joint learning research in biomedical domains. A brief review of the field of joint learning research is given, with emphases on the large-scale data and knowledge...

A Real-Time DSP-Based Imbalance Analysis System for Rotating Machine with Vibration Signal (2008)

Su, Hua, Huang, Linglong, Chong, Kil To

This paper describes a new digital signal processor (DSP) imbalance measurement system dedicated to real-time vibration analysis on rotating machine. To accomplish real-time analysis, the vibration...

Neural Network Based Expert System for Induction Motor Faults Detection (2008)

Su, Hua, Chong, Kil-To

Early detection and diagnosis of incipient induction machine faults increases machinery availability, reduces consequential damage, and improves operational efficiency. However, fault detection using...

Positive solutions of two-point boundary value problems for n-order p-Laplacian operator (2008)

Hua Su

In this paper, we study the existence of positive solutions for the non-linear two-point singular boundary value problem for higher order with p-Laplacian operator. By using the fixed-point index...

Positive solutions of two-point boundary value problems for n-order p-Laplacian operator (2008)

Hua Su

In this paper, we study the existence of positive solutions for the non-linear two-point singular boundary value problem for higher order with p-Laplacian operator. By using the fixed-point index...

Several Existence Theorems of Nonlinear m-Point BVP for an Increasing Homeomorphism and Homomorphism on Time Scales (2008)

Yanbin Sang, Hua Su, Yafeng Xiao

Several existence theorems of positive solutions are established for nonlinear m-point boundary value problem for the following dynamic equations on time scales...

Several Existence Theorems of Nonlinear m-Point BVP for an Increasing Homeomorphism and Homomorphism on Time Scales (2008)

Yanbin Sang, Hua Su, Yafeng Xiao

Several existence theorems of positive solutions are established for nonlinear m-point boundary value problem for the following dynamic equations on time scales (ϕ(uΔ))∇+a(t)f(t,u(t))=0,...

Positive solutions of four-point boundary-value problems for higher-order with $p$-Laplacian operator (2007)

Yunming Zhou, Hua Su

In this paper, we study the existence of positive solutions for nonlinear four-point singular boundary-value problems for higher-order equation with the $p$-Laplacian operator. Using the fixed-point...

Improved Algebraic Algorithm On Point Projection For Bézier Curves (2007)

Chen, Xiao-Diao, Zhou, Yin, Shu, Zhenyu, Su, Hua, Paul, Jean-Claude

This paper presents an improved algebraic pruning method for point projection for Bézier curves. It first turns the point projection into a root finding problem, and provides a simple but easily...

Improved Algebraic Algorithm On Point Projection For Bézier Curves (2007)

Chen, Xiao-Diao, Zhou, Yin, Shu, Zhenyu, Su, Hua, Paul, Jean-Claude

This paper presents an improved algebraic pruning method for point projection for Bézier curves. It first turns the point projection into a root finding problem, and provides a simple but easily...

Genome-wide loss of heterozygosity and copy number alteration in esophageal squamous cell carcinoma using the Affymetrix GeneChip Mapping 10 K array (2006)

Hu, Nan, Wang, Chaoyu, Hu, Ying, Yang, Howard H, Kong, Li-Hui, Lu, Ning, ...

Abstract Background Esophageal squamous cell carcinoma (ESCC) is a common malignancy worldwide. Comprehensive genomic characterization of ESCC will further our understanding of the carcinogenesis...

Recombinant adeno-associated viral vector encoding human VEGF(165) induces neomicrovessel formation in the adult mouse brain (2006)

Shen, Fanxia, Su, Hua, Liu, Weizhong, Kan, Yuet W, Young, William L, Yang, Guo-Yuan

Delivery of therapeutic genes represents a fascinating possibility to accelerate injury-repairing process in tissues that are otherwise difficult to treat, such as cerebral ischemia. Current studies...

Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP (2006)

Jiang, Qi, Su, Hua, Knudsen, Geoffry, Helms, Whitney, Su, Lishan

Abstract Background Generation of functional CD4 + CD8 - CD25 + regulatory T cells (Treg) in the murine thymus depends on FoxP3. Removal of the thymus from neonatal mice has been shown to result in a...

Recombinant adeno-associated viral vector encoding human VEGF165 induces neomicrovessel formation in the adult mouse brain. (2006)

Shen, Fanxia, Su, Hua, Liu, Weizhong, Kan, Yuet W, Young, William L, Yang, Guo-Yuan

Delivery of therapeutic genes represents a fascinating possibility to accelerate injury-repairing process in tissues that are otherwise difficult to treat, such as cerebral ischemia. Current studies...

Positive solutions of four-point boundary-value problems for four-order p-Laplacian dynamic equations on time scales (2006)

Hua Su, Baohe Wang, Zhongli Wei

We study the existence of positive solutions for the nonlinear four-point singular boundary-value problem with $p$-Laplacian operator on time scales. By using the fixed-point index theory, the...

A framework of integrating gene relations from heterogeneous data sources: an experiment on Arabidopsis thaliana (2006)

Li, Jiexun, Li, Xin, Su, Hua, Chen, Hsinchun, Galbraith, David W.

One of the most important goals of biological investigation is to uncover gene functional relations. In this study we propose a framework for extraction and integration of gene functional relations...

Adeno-associated viral vector delivers card iac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts (2004)

Su, Hua, Joho, S, Huang, Y, Barcena, A, Arakawa-Hoyt, J, Grossman, W, ...

It has been shown that the adeno-associated virus (AAV) vector can deliver the VEGF gene efficiently into the ischemic mouse myocardium. However, the AAV genomes can be found in extracardiac organs...

Selection and validation of endogenous reference genes using a high throughput approach (2004)

Jin, Ping, Zhao, Yingdong, Ngalame, Yvonne, Panelli, Monica C, Nagorsen, Dirk, Monsurró, Vladia, ...

Abstract Background Endogenous reference genes are commonly used to normalize expression levels of other genes with the assumption that the expression of the former is constant in different tissues...

Extracting gene pathway relations using a hybrid grammar: the Arizona Relation Parser (2004)

McDonald, Daniel M., Chen, Hsinchun, Su, Hua, Marshall, Byron B.

Motivation: Text-mining research in the biomedical domain has been motivated by the rapid growth of new research findings. Improving the accessibility of findings has potential to speed hypothesis...

Informative Experimental Design for Electronic Circuits (1998)

Zahid Malik, Hua Su, John Nelder

|This paper presents the case against two widespread practices in designing engineering experiments, which are (i) to vary one factor at a time (the OFAT approach) and (ii) to generate experimental...

The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages

De Voss, James J., Rutter, Kerry, Schroeder, Benjamin G., Su, Hua, Zhu, YaQi, Barry, Clifton E.

Mycobacterium tuberculosis is an important pathogen of mammals that relies on 2-hydroxyphenyloxazoline-containing siderophore molecules called mycobactins for the acquisition of iron in the...

Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart

Su, Hua, Lu, Ronghua, Kan, Yuet Wai

Vascular endothelial growth factor (VEGF) plays important roles in physiological and pathological angiogenesis. Recent studies have demonstrated that direct injection of VEGF protein, plasmid DNA, or...

Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice

Su, Hua, Lu, Ronghua, Chang, Judy C., Kan, Yuet Wai

About 70% of hepatocellular carcinomas are known to express α-fetoprotein, which is normally expressed in fetal but not in adult livers. To induce herpes simplex virus-thymidine kinase expression in...

Expression and Stress-Dependent Induction of Potassium Channel Transcripts in the Common Ice Plant1

Su, Hua, Golldack, Dortje, Katsuhara, Maki, Zhao, Chengsong, Bohnert, Hans J.

We have characterized transcripts for three potassium channel homologs in the AKT/KAT subfamily (Shaker type) from the common ice plant (Mesembryanthemum crystallinum), with a focus on their...

Subclinical Chlamydial Infection of the Female Mouse Genital Tract Generates a Potent Protective Immune Response: Implications for Development of Live Attenuated Chlamydial Vaccine Strains

Su, Hua, Messer, Ronald, Whitmire, William, Hughes, Scott, Caldwell, Harlan D.

Chlamydia trachomatis is a major cause of sexually transmitted disease (STD) for which a vaccine is needed. CD4+ T-helper type 1 (Th1) cell-mediated immunity is an important component of protective...

Immunity to Murine Chlamydia trachomatis Genital Tract Reinfection Involves B Cells and CD4+ T Cells but Not CD8+ T Cells

Morrison, Sandra G., Su, Hua, Caldwell, Harlan D., Morrison, Richard P.

CD4+ T-helper type 1 (Th1) responses are essential for the resolution of a primary Chlamydia trachomatis genital tract infection; however, elements of the immune response that function in resistance...

Sulfated Polysaccharides and a Synthetic Sulfated Polymer Are Potent Inhibitors of Chlamydia trachomatis Infectivity In Vitro but Lack Protective Efficacy in an In Vivo Murine Model of Chlamydial Genital Tract Infection

Su, Hua, Caldwell, Harlan D.

Heparin, dextran sulfate, pentosan polysulfate, and a sulfated synthetic copolymer of acrylic acid and vinyl alcohol were shown to be potent inhibitors of Chlamydia trachomatis infectivity for...

Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model

Su, Hua, Arakawa-Hoyt, Janice, Kan, Yuet Wai

Intramyocardial injection of genes encoding angiogenic factors could provide a useful approach for the treatment of ischemic heart disease. However, uncontrolled expression of angiogenic factors in...

Enhanced Immunogenicity to Mycobacterium tuberculosis by Vaccination with an Alphavirus Plasmid Replicon Expressing Antigen 85A

Kirman, Joanna R., Turon, Tara, Su, Hua, Li, Amy, Kraus, Carl, Polo, John M., ...

The immunogenicity of a plasmid DNA vaccine incorporating Sindbis virus RNA replicase functions (pSINCP) and expressing antigen 85A (Ag85A) from Mycobacterium tuberculosis was compared with a...

Group A Streptococcus Gene Expression in Humans and Cynomolgus Macaques with Acute Pharyngitis

Virtaneva, Kimmo, Graham, Morag R., Porcella, Stephen F., Hoe, Nancy P., Su, Hua, Graviss, Edward A., ...

The molecular mechanisms used by group A Streptococcus (GAS) to survive on the host mucosal surface and cause acute pharyngitis are poorly understood. To provide new information about GAS...

The Expression of HAK-Type K+ Transporters Is Regulated in Response to Salinity Stress in Common Ice Plant1

Su, Hua, Golldack, Dortje, Zhao, Chengsong, Bohnert, Hans J.

Four transcripts homologous to K+ transporters of the HAK/KT/KUP family have been characterized from the common ice plant (Mesembryanthemum crystallinum). We report tissue-specific expression of...

Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts

Su, Hua, Joho, Shuji, Huang, Yu, Barcena, Alicia, Arakawa-Hoyt, Janice, Grossman, William, ...

It has been shown that the adeno-associated virus (AAV) vector can deliver the VEGF gene efficiently into the ischemic mouse myocardium. However, the AAV genomes can be found in extracardiac organs...

A Hypoxia-Regulated Adeno-Associated Virus Vector for Cancer-Specific Gene Therapy1

Ruan, Hangjun, Su, Hua, Hu, Lily, Lamborn, Kathleen R, Kan, YW, Deen, Dennis F

The presence of hypoxic cells in human brain tumors is an important factor leading to resistance to radiation therapy. However, this physiological difference between normal tissues and tumors also...

The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages

De Voss, James J., Rutter, Kerry, Schroeder, Benjamin G., Su, Hua, Zhu, YaQi, Barry, Clifton E.

Mycobacterium tuberculosis is an important pathogen of mammals that relies on 2-hydroxyphenyloxazoline-containing siderophore molecules called mycobactins for the acquisition of iron in the...

Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart

Su, Hua, Lu, Ronghua, Kan, Yuet Wai

Vascular endothelial growth factor (VEGF) plays important roles in physiological and pathological angiogenesis. Recent studies have demonstrated that direct injection of VEGF protein, plasmid DNA, or...

Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice

Su, Hua, Lu, Ronghua, Chang, Judy C., Kan, Yuet Wai

About 70% of hepatocellular carcinomas are known to express α-fetoprotein, which is normally expressed in fetal but not in adult livers. To induce herpes simplex virus-thymidine kinase expression in...

Expression and Stress-Dependent Induction of Potassium Channel Transcripts in the Common Ice Plant1

Su, Hua, Golldack, Dortje, Katsuhara, Maki, Zhao, Chengsong, Bohnert, Hans J.

We have characterized transcripts for three potassium channel homologs in the AKT/KAT subfamily (Shaker type) from the common ice plant (Mesembryanthemum crystallinum), with a focus on their...

Subclinical Chlamydial Infection of the Female Mouse Genital Tract Generates a Potent Protective Immune Response: Implications for Development of Live Attenuated Chlamydial Vaccine Strains

Su, Hua, Messer, Ronald, Whitmire, William, Hughes, Scott, Caldwell, Harlan D.

Chlamydia trachomatis is a major cause of sexually transmitted disease (STD) for which a vaccine is needed. CD4+ T-helper type 1 (Th1) cell-mediated immunity is an important component of protective...

Immunity to Murine Chlamydia trachomatis Genital Tract Reinfection Involves B Cells and CD4+ T Cells but Not CD8+ T Cells

Morrison, Sandra G., Su, Hua, Caldwell, Harlan D., Morrison, Richard P.

CD4+ T-helper type 1 (Th1) responses are essential for the resolution of a primary Chlamydia trachomatis genital tract infection; however, elements of the immune response that function in resistance...

Sulfated Polysaccharides and a Synthetic Sulfated Polymer Are Potent Inhibitors of Chlamydia trachomatis Infectivity In Vitro but Lack Protective Efficacy in an In Vivo Murine Model of Chlamydial Genital Tract Infection

Su, Hua, Caldwell, Harlan D.

Heparin, dextran sulfate, pentosan polysulfate, and a sulfated synthetic copolymer of acrylic acid and vinyl alcohol were shown to be potent inhibitors of Chlamydia trachomatis infectivity for...

Adeno-associated viral vector-mediated hypoxia response element-regulated gene expression in mouse ischemic heart model

Su, Hua, Arakawa-Hoyt, Janice, Kan, Yuet Wai

Intramyocardial injection of genes encoding angiogenic factors could provide a useful approach for the treatment of ischemic heart disease. However, uncontrolled expression of angiogenic factors in...

Enhanced Immunogenicity to Mycobacterium tuberculosis by Vaccination with an Alphavirus Plasmid Replicon Expressing Antigen 85A

Kirman, Joanna R., Turon, Tara, Su, Hua, Li, Amy, Kraus, Carl, Polo, John M., ...

The immunogenicity of a plasmid DNA vaccine incorporating Sindbis virus RNA replicase functions (pSINCP) and expressing antigen 85A (Ag85A) from Mycobacterium tuberculosis was compared with a...

Group A Streptococcus Gene Expression in Humans and Cynomolgus Macaques with Acute Pharyngitis

Virtaneva, Kimmo, Graham, Morag R., Porcella, Stephen F., Hoe, Nancy P., Su, Hua, Graviss, Edward A., ...

The molecular mechanisms used by group A Streptococcus (GAS) to survive on the host mucosal surface and cause acute pharyngitis are poorly understood. To provide new information about GAS...

The Expression of HAK-Type K+ Transporters Is Regulated in Response to Salinity Stress in Common Ice Plant1

Su, Hua, Golldack, Dortje, Zhao, Chengsong, Bohnert, Hans J.

Four transcripts homologous to K+ transporters of the HAK/KT/KUP family have been characterized from the common ice plant (Mesembryanthemum crystallinum). We report tissue-specific expression of...

Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts

Su, Hua, Joho, Shuji, Huang, Yu, Barcena, Alicia, Arakawa-Hoyt, Janice, Grossman, William, ...

It has been shown that the adeno-associated virus (AAV) vector can deliver the VEGF gene efficiently into the ischemic mouse myocardium. However, the AAV genomes can be found in extracardiac organs...

A Hypoxia-Regulated Adeno-Associated Virus Vector for Cancer-Specific Gene Therapy1

Ruan, Hangjun, Su, Hua, Hu, Lily, Lamborn, Kathleen R, Kan, YW, Deen, Dennis F

The presence of hypoxic cells in human brain tumors is an important factor leading to resistance to radiation therapy. However, this physiological difference between normal tissues and tumors also...

iNOS activity is critical for the clearance of Burkholderia mallei from infected RAW 264.7 murine macrophages

Brett, Paul J, Burtnick, Mary N, Su, Hua, Nair, Vinod, Gherardini, Frank C

Burkholderia mallei is a facultative intracellular pathogen that can cause fatal disease in animals and humans. To better understand the role of phagocytic cells in the control of infections caused...

Vaccination against Chlamydial Genital Tract Infection after Immunization with Dendritic Cells Pulsed Ex Vivo with Nonviable Chlamydiae

Su, Hua, Messer, Ronald, Whitmire, William, Fischer, Elizabeth, Portis, John C., Caldwell, Harlan D.

Chlamydia trachomatis, an obligate intracellular bacterial pathogen of mucosal surfaces, is a major cause of preventable blindness and sexually transmitted diseases for which vaccines are badly...

Permanent Coronary Artery Occlusion: Cardiovascular MR Imaging Is Platform for Percutaneous Transendocardial Delivery and Assessment of Gene Therapy in Canine Model

Saeed, Maythem, Martin, Alastair, Jacquier, Alexis, Bucknor, Matthew, Saloner, David, Do, Loi, ...

Purpose: To provide evidence that vascular endothelial growth factor (VEGF) genes delivered transendocardially with magnetic resonance (MR) imaging guidance may neovascularize or improve vascular...