Silander, Kaisa, Tang, Hua, Myles, Sean, Jakkula, Eveliina, Timpson, Nicholas J, Cavalli-Sforza, Luigi, ...
Abstract A 100 kb region on 9p21.3 harbors two major disease susceptibility loci: one for type 2 diabetes (T2D) and one for coronary heart disease (CHD). The single nucleotide polymorphisms (SNPs)...
Dark-Sates in Electromagnetically Induced Transparency Controlled by a Microwave Field (2009)
Luo, Bin, Tang, Hua, Guo, Hong
The rigorous dark-sate conditions, i.e., two-photon resonance, for a Lambda-type electromagnetically induced transparency (EIT) are extended with the system controlled by a microwave field. The...
Kazrin F is involved in apoptosis and interacts with BAX and ARC (2009)
Wang, Qiong, Liu, Min, Li, Xin, Chen, Lu, Tang, Hua
Kazrin has recently been identified as a functional protein that is involved in cell–cell junctions and in signal transduction. Here, we identified a new isoform, Kazrin F, which is 518 aa in...
Admixture mapping of quantitative trait loci for blood lipids in African-Americans (2009)
Basu, Analabha, Tang, Hua, Lewis, Cora E., North, Kari, Curb, J. David, Quertermous, Thomas, ...
Blood lipid levels, including low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG), are highly heritable traits and major risk factors for...
MINLP Based Topology Synthesis for Delta-Sigma Modulators Optimized for (2008)
Hua Tang, Ying Wei, Alex Doboli
This paper proposes a novel architecture synthesis algorithm for single-loop single-bit ∆Σ modulators. We defined a generic modulator architecture, derived its transfer function (TF), and used the...
Pei Wang, Hua Tang, Heidi Zhang, Jeffrey Whiteaker, A G. Paulovich, Martin Mcintosh, ...
We propose a two-step normalization procedure for high-throughput mass spectrometry (MS) data, which is a necessary step in biomarker clustering or classification. First, a global normalization step...
Assimes, Themistocles L., Knowles, Joshua W., Basu, Analabha, Iribarren, Carlos, Southwick, Audrey, Tang, Hua, ...
A susceptibility locus for coronary artery disease (CAD) at chromosome 9p21 has recently been reported, which may influence the age of onset of CAD. We sought to replicate these findings among white...
Combining multiple family-based association studies (2007)
Tang, Hua, Peng, Jie, Wang, Pei, Coram, Marc, Hsu, Li
Abstract While high-throughput genotyping technologies are becoming readily available, the merit of using these technologies to perform genome-wide association studies has not been established. One...
Peng, Jie, Wang, Pei, Tang, Hua
Abstract In the fast-developing field of expression quantitative traits loci (eQTL) studies, much interest has been concentrated on detecting genomic regions containing transcriptional regulators...
Estimation of the allele frequency at genetic markers is a key ingredient in biological and biomedical research, such as studies of human genetic variation or of the genetic etiology of heritable...
Reduced selection leads to accelerated gene loss in Shigella (2007)
Hershberg, Ruth, Tang, Hua, Petrov, Dmitri A
Abstract Background Obligate pathogenic bacteria lose more genes relative to facultative pathogens, which, in turn, lose more genes than free-living bacteria. It was suggested that the increased gene...
A statistical method for chromatographic alignment of LC-MS data (2007)
Wang, Pei, Tang, Hua, Fitzgibbon, Matthew P., Mcintosh, Martin, Coram, Marc, Zhang, Hui, ...
Integrated liquid-chromatography mass-spectrometry (LC-MS) is becoming a widely used approach for quantifying the protein composition of complex samples. The output of the LC-MS system measures the...
Complementarity in a macroscopic observation (2007)
Cao, De-Zhong, Xiong, Jun, Tang, Hua, Lin, Lu-Fang, Zhang, Su-Heng, Wang, Kaige
Complementarity is usually considered as a phenomenon of microscopic systems. In this paper we report an experimental observation of complementarity in the correlated double-slit interference with a...
A statistical method for chromatographic alignment of LC-MS data (2006)
Wang, Pei, Coram, Marc, Tang, Hua, Fitzgibbon, Matthew P, Zhang, Hui, Yi, Eugene, ...
Integrated liquid-chromatography mass-spectrometry (LC-MS) is becoming a widely used approach for quantifying the protein composition of complex samples. The output of the LC-MS system measures the...
A statistical method for chromatographic alignment of LC-MS data (2006)
Wang, Pei, Coram, Marc, Tang, Hua, Fitzgibbon, Matthew P, Zhang, Hui, Yi, Eugene, ...
Integrated liquid-chromatography mass-spectrometry (LC-MS) is becoming a widely used approach for quantifying the protein composition of complex samples. The output of the LC-MS system measures the...
The standard methods for computing the number of nonsynonymous substitutions (Ka) lump all amino acid changes into one single class, even though their rates of substitution vary by at least 10-fold...
Locally weighted transmission/disequilibrium test for genetic association analysis (2005)
Hsu, Li, Yu, Xuesong, Houwing-Duistermaat, Jeanine J, Uh, Hae-Won, El Galta, Rachid, Lebrec, Jeremie JP, ...
Abstract The transmission/disequilibrium test statistic has been used for assessing genetic association in affected-parent trios. In the presence of multiple tightly linked marker loci where local...
Ethnicity and Human Genetic Linkage Maps (2005)
Jorgenson, Eric, Tang, Hua, Gadde, Maya, Province, Mike, Leppert, Mark, Kardia, Sharon, ...
Human genetic linkage maps are based on rates of recombination across the genome. These rates in humans vary by the sex of the parent from whom alleles are inherited, by chromosomal position, and by...
Tang, Hua, Quertermous, Tom, Rodriguez, Beatriz, Kardia, Sharon LR, Zhu, Xiaofeng, Brown, Andrew, ...
We have analyzed genetic data for 326 microsatellite markers that were typed uniformly in a large multiethnic population-based sample of individuals as part of a study of the genetics of hypertension...
Tang, Hua, Wei, Ying, Doboli, Alex
This paper proposes a novel architecture synthesis algorithm for single-loop single-bit ?S modulators. We defined a generic modulator architecture and derived its noise and signal transfer function...
Tang, Hua, Wei, Ying, Doboli, Alex
This paper proposes a novel architecture synthesis algorithm for single-loop single-bit ?S modulators. We defined a generic modulator architecture and derived its noise and signal transfer function...
Thesis (Ph. D.)--Stony Brook University, 2005.
Some rules in protein evolution / (2005)
Thesis (Ph. D.)--University of Chicago, Dept. of Ecology and Evolution, June 2005.
Hui Zhang, Simona Doboli, Hua Tang, Alex Doboli
This paper presents a method for fast time-domain simulation of analog systems with nonlinear parameters. Specifically, the paper focuses on £¥ ¤ analog-to-digital converters (ADC). The method...
Qian, Wei, Jia, Yantao, Ren, Shuang-Xi, He, Yong-Qiang, Feng, Jia-Xun, Lu, Ling-Feng, ...
Xanthomonas campestris pathovar campestris (Xcc) is the causative agent of crucifer black rot disease, which causes severe losses in agricultural yield world-wide. This bacterium is a model organism...
The standard methods for computing the number of nonsynonymous substitutions (Ka) lump all amino acid changes into one single class, even though their rates of substitution vary by at least 10 fold...
Qian, Wei, Jia, Yantao, Ren, Shuang-Xi, He, Yong-Qiang, Feng, Jia-Xun, Lu, Ling-Feng, ...
Xanthomonas campestris pathovar campestris (Xcc) is the causative agent of crucifer black rot disease, which causes severe losses in agricultural yield world-wide. This bacterium is a model organism...
The standard methods for computing the number of nonsynonymous substitutions (Ka) lump all amino acid changes into one single class, even though their rates of substitution vary by at least 10 fold...
A Universal Evolutionary Index for Amino Acid Changes (2004)
Tang, Hua, Wyckoff, Gerald J., Lu, Jian, Wu, Chung-I
Different nonsynonymous changes may be under different selective pressure during evolution. Of the 190 possible interchanges among the 20 amino acids, only 75 can be attained by a single-base...
A Universal Evolutionary Index for Amino Acid Changes (2004)
Tang, Hua, Wyckoff, Gerald J., Lu, Jian, Wu, Chung-I
Different nonsynonymous changes may be under different selective pressure during evolution. Of the 190 possible interchanges among the 20 amino acids, only 75 can be attained by a single-base...
A Universal Evolutionary Index for Amino Acid Changes (2004)
Tang, Hua, Wyckoff, Gerald J., Lu, Jian, Wu, Chung-I
Different nonsynonymous changes may be under different selective pressure during evolution. Of the 190 possible interchanges among the 20 amino acids, only 75 can be attained by a single-base...
Wang, Hurng-Yi, Tang, Hua, Shen, C. K. James, Wu, Chung-I
In an attempt to identify all fast-evolving genes between human and other primates, we found the three glycophorins, GPA, GPB and GPE, to have the highest rate of nonsynonymous substitutions among...
Wang, Hurng-Yi, Tang, Hua, Shen, C.-K. James, Wu, Chung-I
In an attempt to identify all fast-evolving genes between human and other primates, we found three glycophorins, GPA, GPB, and GPE, to have the highest rate of nonsynonymous substitutions among the...
Wang, Hurng-Yi, Tang, Hua, Shen, C. K. James, Wu, Chung-I
In an attempt to identify all fast-evolving genes between human and other primates, we found the three glycophorins, GPA, GPB and GPE, to have the highest rate of nonsynonymous substitutions among...
Categorization of humans in biomedical research: genes, race and disease (2002)
Risch, Neil, Burchard, Esteban, Ziv, Elad, Tang, Hua
Abstract A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. Some claim 'no biological basis for race' while others advocate a 'race-neutral'...
Categorization of humans in biomedical research: genes, race and disease (2002)
Risch, Neil, Burchard, Esteban, Ziv, Elad, Tang, Hua
A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. Some claim ‘no biological basis for race’ while others advocate a ‘race-neutral’...
Statistical methods for two problems in DNA sequence comparisons / (2002)
Tang, Hua., Siegmund, David O. Advisor
Submitted to the Department of Statistics.
Three essays on continuous time finance (2001)
In first essay, I present a general equilibrium model of financial asset pricing where market can be incomplete. The focus is on the effects of economics fundamentals on capital asset pricing model....
Three essays on continuous time finance. (2001)
Source: Dissertation Abstracts International, Volume: 61-12, Section: A, page: 4885.
Thesis (Ph. D.)--Dept. of Biology, University of Utah, 1996.
The Raman diagnostics and process physics of laser-induced surface modifications /--Hua Tang. (1992)
Department: Applied Physics.
Thesis (Ph. D.)--Columbia University, 1992.
Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors
Levanon, Ditsa, Goldstein, Robert E., Bernstein, Yael, Tang, Hua, Goldenberg, Dalia, Stifani, Stefano, ...
The mammalian AML/CBFα runt domain (RD) transcription factors regulate hematopoiesis and osteoblast differentiation. Like their Drosophila counterparts, most mammalian RD proteins terminate in a...
Tang, Hua, Hornstein, Eran, Stolovich, Miri, Levy, Galit, Livingstone, Mark, Templeton, Dennis, ...
Vertebrate TOP mRNAs contain an oligopyrimidine tract at their 5′ termini (5′TOP) and encode components of the translational machinery. Previously it has been shown that they are subject to...
Stolovich, Miri, Tang, Hua, Hornstein, Eran, Levy, Galit, Cohen, Ruth, Bae, Sun Sik, ...
Translation of terminal oligopyrimidine tract (TOP) mRNAs, which encode multiple components of the protein synthesis machinery, is known to be controlled by mitogenic stimuli. We now show that the...
Categorization of humans in biomedical research: genes, race and disease
Risch, Neil, Burchard, Esteban, Ziv, Elad, Tang, Hua
A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. An epidemiologic perspective on the issue of human categorization in biomedical and genetic...
Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways
Schuurmans, Carol, Armant, Olivier, Nieto, Marta, Stenman, Jan M, Britz, Olivier, Klenin, Natalia, ...
Neocortical projection neurons, which segregate into six cortical layers according to their birthdate, have diverse morphologies, axonal projections and molecular profiles, yet they share a common...
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human
Song, Huai-Dong, Tu, Chang-Chun, Zhang, Guo-Wei, Wang, Sheng-Yue, Zheng, Kui, Lei, Lian-Cheng, ...
The genomic sequences of severe acute respiratory syndrome coronaviruses from human and palm civet of the 2003/2004 outbreak in the city of Guangzhou, China, were nearly identical. Phylogenetic...
Qian, Wei, Jia, Yantao, Ren, Shuang-Xi, He, Yong-Qiang, Feng, Jia-Xun, Lu, Ling-Feng, ...
Xanthomonas campestris pathovar campestris (Xcc) is the causative agent of crucifer black rot disease, which causes severe losses in agricultural yield world-wide. This bacterium is a model organism...
Tang, Hua, Siegmund, David O, Shen, Peidong, Oefner, Peter J, Feldman, Marcus W
This article proposes a method of estimating the time to the most recent common ancestor (TMRCA) of a sample of DNA sequences. The method is based on the molecular clock hypothesis, but avoids...
Genomewide Evolutionary Rates in Laboratory and Wild Yeast
Ronald, James, Tang, Hua, Brem, Rachel B.
As wild organisms adapt to the laboratory environment, they become less relevant as biological models. It has been suggested that a commonly used S. cerevisiae strain has rapidly accumulated...
Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors
Levanon, Ditsa, Goldstein, Robert E., Bernstein, Yael, Tang, Hua, Goldenberg, Dalia, Stifani, Stefano, ...
The mammalian AML/CBFα runt domain (RD) transcription factors regulate hematopoiesis and osteoblast differentiation. Like their Drosophila counterparts, most mammalian RD proteins terminate in a...
Tang, Hua, Hornstein, Eran, Stolovich, Miri, Levy, Galit, Livingstone, Mark, Templeton, Dennis, ...
Vertebrate TOP mRNAs contain an oligopyrimidine tract at their 5′ termini (5′TOP) and encode components of the translational machinery. Previously it has been shown that they are subject to...
Stolovich, Miri, Tang, Hua, Hornstein, Eran, Levy, Galit, Cohen, Ruth, Bae, Sun Sik, ...
Translation of terminal oligopyrimidine tract (TOP) mRNAs, which encode multiple components of the protein synthesis machinery, is known to be controlled by mitogenic stimuli. We now show that the...
Categorization of humans in biomedical research: genes, race and disease
Risch, Neil, Burchard, Esteban, Ziv, Elad, Tang, Hua
A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. An epidemiologic perspective on the issue of human categorization in biomedical and genetic...
Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways
Schuurmans, Carol, Armant, Olivier, Nieto, Marta, Stenman, Jan M, Britz, Olivier, Klenin, Natalia, ...
Neocortical projection neurons, which segregate into six cortical layers according to their birthdate, have diverse morphologies, axonal projections and molecular profiles, yet they share a common...
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human
Song, Huai-Dong, Tu, Chang-Chun, Zhang, Guo-Wei, Wang, Sheng-Yue, Zheng, Kui, Lei, Lian-Cheng, ...
The genomic sequences of severe acute respiratory syndrome coronaviruses from human and palm civet of the 2003/2004 outbreak in the city of Guangzhou, China, were nearly identical. Phylogenetic...
Qian, Wei, Jia, Yantao, Ren, Shuang-Xi, He, Yong-Qiang, Feng, Jia-Xun, Lu, Ling-Feng, ...
Xanthomonas campestris pathovar campestris (Xcc) is the causative agent of crucifer black rot disease, which causes severe losses in agricultural yield world-wide. This bacterium is a model organism...
Risch, Neil, Tang, Hua, Katzenstein, Howard, Ekstein, Josef
The presence of four lysosomal storage diseases (LSDs) at increased frequency in the Ashkenazi Jewish population has suggested to many the operation of natural selection (carrier advantage) as the...
Tang, Hua, Quertermous, Tom, Rodriguez, Beatriz, Kardia, Sharon L. R., Zhu, Xiaofeng, Brown, Andrew, ...
We have analyzed genetic data for 326 microsatellite markers that were typed uniformly in a large multiethnic population-based sample of individuals as part of a study of the genetics of hypertension...
Ethnicity and Human Genetic Linkage Maps
Jorgenson, Eric, Tang, Hua, Gadde, Maya, Province, Mike, Leppert, Mark, Kardia, Sharon, ...
Human genetic linkage maps are based on rates of recombination across the genome. These rates in humans vary by the sex of the parent from whom alleles are inherited, by chromosomal position, and by...
Tang, Hua, Siegmund, David O, Shen, Peidong, Oefner, Peter J, Feldman, Marcus W
This article proposes a method of estimating the time to the most recent common ancestor (TMRCA) of a sample of DNA sequences. The method is based on the molecular clock hypothesis, but avoids...
Genomewide Evolutionary Rates in Laboratory and Wild Yeast
Ronald, James, Tang, Hua, Brem, Rachel B.
As wild organisms adapt to the laboratory environment, they become less relevant as biological models. It has been suggested that a commonly used S. cerevisiae strain has rapidly accumulated...
Reconstructing Genetic Ancestry Blocks in Admixed Individuals
Tang, Hua, Coram, Marc, Wang, Pei, Zhu, Xiaofeng, Risch, Neil
A chromosome in an individual of recently admixed ancestry resembles a mosaic of chromosomal segments, or ancestry blocks, each derived from a particular ancestral population. We consider the problem...
Gojobori, Jun, Tang, Hua, Akey, Joshua M., Wu, Chung-I
The selective forces acting on amino acid substitutions may be different in the two phases of molecular evolution: polymorphism and fixation. Negative selection and genetic drift may dominate the...
Controlling for false positive findings of trans-hubs in expression quantitative trait loci mapping
Peng, Jie, Wang, Pei, Tang, Hua
In the fast-developing field of expression quantitative traits loci (eQTL) studies, much interest has been concentrated on detecting genomic regions containing transcriptional regulators that...
Combining multiple family-based association studies
Tang, Hua, Peng, Jie, Wang, Pei, Coram, Marc, Hsu, Li
While high-throughput genotyping technologies are becoming readily available, the merit of using these technologies to perform genome-wide association studies has not been established. One major...
Reduced selection leads to accelerated gene loss in Shigella
Hershberg, Ruth, Tang, Hua, Petrov, Dmitri A
The rate of gene loss was studied in the facultative pathogens, E. coli and Shigella, and was found to be greater in the more niche-limited Shigella. This is demonstrated to be due to a genome-wide...
Ancestry–Environment Interactions and Asthma Risk among Puerto Ricans
Choudhry, Shweta, Burchard, Esteban González, Borrell, Luisa N., Tang, Hua, Gomez, Ivan, Naqvi, Mariam, ...
Background: Puerto Ricans, an admixed population of African, European, and Native American ancestries, have the highest asthma prevalence, morbidity, and mortality rates of any United States'...
Dissecting Complex Diseases in Complex Populations: Asthma in Latino Americans
Choudhry, Shweta, Seibold, Max A., Borrell, Luisa N., Tang, Hua, Serebrisky, Denise, Chapela, Rocio, ...
Asthma is a common but complex respiratory ailment; current data indicate that interaction of genetic and environmental factors lead to its clinical expression. In the United States, asthma...
Wang, Xuemin, Fonseca, Bruno D., Tang, Hua, Liu, Rui, Elia, Androulla, Clemens, Michael J., ...
Signaling through mammalian target of rapamycin complex 1 (mTORC1) is stimulated by amino acids and insulin. Insulin inactivates TSC1/2, the GTPase-activator complex for Rheb, and Rheb·GTP activates...
Tang, Hua, Choudhry, Shweta, Mei, Rui, Morgan, Martin, Rodriguez-Cintron, William, Burchard, Esteban Gonzalez, ...
Silander, Kaisa, Tang, Hua, Myles, Sean, Jakkula, Eveliina, Timpson, Nicholas J, Cavalli-Sforza, Luigi, ...
A 100 kb region on 9p21.3 harbors two major disease susceptibility loci: one for type 2 diabetes (T2D) and one for coronary heart disease (CHD). The single nucleotide polymorphisms (SNPs) associated...
Hancock, Dana B., Romieu, Isabelle, Shi, Min, Sienra-Monge, Juan-Jose, Wu, Hao, Chiu, Grace Y., ...
Many candidate genes have been studied for asthma, but replication has varied. Novel candidate genes have been identified for various complex diseases using genome-wide association studies (GWASs)....
Assimes, Themistocles L., Knowles, Joshua W., Basu, Analabha, Iribarren, Carlos, Southwick, Audrey, Tang, Hua, ...
A susceptibility locus for coronary artery disease (CAD) at chromosome 9p21 has recently been reported, which may influence the age of onset of CAD. We sought to replicate these findings among white...