Hui-I Kao

Dna2p Helicase/Nuclease Is a Tracking Protein, Like FEN1, for Flap Cleavage during Okazaki Fragment Maturation (2004)

Kao, Hui-I, Campbell, Judith L., Bambara, Robert A.

During cellular DNA replication the lagging strand is generated as discontinuous segments called Okazaki fragments. Each contains an initiator RNA primer that is removed prior to joining of the...

Identification of rad27 Mutations That Confer Differential Defects in Mutation Avoidance, Repeat Tract Instability, and Flap Cleavage

Xie, Yali, Liu, Yuan, Argueso, Juan Lucas, Henricksen, Leigh A., Kao, Hui-I, Bambara, Robert A., ...

In eukaryotes, the nuclease activity of Rad27p (Fen1p) is thought to play a critical role in lagging-strand DNA replication by removing ribonucleotides present at the 5′ ends of Okazaki fragments....

WRN Helicase and FEN-1 Form a Complex upon Replication Arrest and Together Process Branchmigrating DNA Structures Associated with the Replication Fork

Sharma, Sudha, Otterlei, Marit, Sommers, Joshua A., Driscoll, Henry C., Dianov, Grigory L., Kao, Hui-I, ...

Werner Syndrome is a premature aging disorder characterized by genomic instability, elevated recombination, and replication defects. It has been hypothesized that defective processing of certain...

Identification of rad27 Mutations That Confer Differential Defects in Mutation Avoidance, Repeat Tract Instability, and Flap Cleavage

Xie, Yali, Liu, Yuan, Argueso, Juan Lucas, Henricksen, Leigh A., Kao, Hui-I, Bambara, Robert A., ...

In eukaryotes, the nuclease activity of Rad27p (Fen1p) is thought to play a critical role in lagging-strand DNA replication by removing ribonucleotides present at the 5′ ends of Okazaki fragments....

WRN Helicase and FEN-1 Form a Complex upon Replication Arrest and Together Process Branchmigrating DNA Structures Associated with the Replication Fork

Sharma, Sudha, Otterlei, Marit, Sommers, Joshua A., Driscoll, Henry C., Dianov, Grigory L., Kao, Hui-I, ...

Werner Syndrome is a premature aging disorder characterized by genomic instability, elevated recombination, and replication defects. It has been hypothesized that defective processing of certain...