Hui Zhou

Publication List Details

Period

1992 - 2009

Number

86

Co-Authors

Genome-wide analysis of chicken snoRNAs provides unique implications for the evolution of vertebrate snoRNAs (2009)

Shao, Peng, Yang, Jian-Hua, Zhou, Hui, Guan, Dao-Gang, Qu, Liang-Hu

Abstract Background Small nucleolar RNAs (snoRNAs) represent one of the largest groups of functionally diverse trans-acting non-protein-coding (npc) RNAs currently known in eukaryotic cells. Chicken...

Genome-wide evolutionary analysis of the noncoding RNA genes and noncoding DNA of Paramecium tetraurelia (2009)

Chen, Chun-Long, Zhou, Hui, Liao, Jian-You, Qu, Liang-Hu, Amar, Laurence

The compact genome of the unicellular eukaryote Paramecium tetraurelia contains noncoding DNA (ncDNA) distributed into >39,000 intergenic sequences and >90,000 introns of 390 base pairs (bp) and 25...

Class IIC {alpha}-mannosidase AfAms1 is required for morphogenesis and cellular function in Aspergillus fumigatus (2009)

Li, Yanjie, Fang, Wenxia, Zhang, Lei, Ouyang, Haomiao, Zhou, Hui, Luo, Yuanming, ...

The mammalian ER/cytosolic α-mannosidase (Man2C1p), yeast vacuolar α-mannosidase (Ams1p) and the Aspergillus nidulans α-mannosidase are members of Class IIC subgroup, which is involved in...

Strain distribution pattern of immune nephritis--a follow-up study (2008)

Xie, Chun, Rahman, Ziaur S. M., Xie, Shangkui, Zhu, Jiankun, Du, Yong, Qin, Xiangmei, ...

Previous studies have indicated that the NZW, DBA/1, 129/sv and BUB strains are particularly sensitive to experimental anti-glomerular basement membrane (GBM)-induced immune nephritis. The present...

Stress-induced tRNA-derived RNAs: a novel class of small RNAs in the primitive eukaryote Giardia lamblia (2008)

Li, Yan, Luo, Jun, Zhou, Hui, Liao, Jian-You, Ma, Li-Ming, Chen, Yue-Qin, ...

Giardia lamblia is an early diverging and evolutionarily successful protozoan as it can enter into a dormant cyst stage from a vegetative trophozoite. During dormant stage, its metabolic rate...

PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr (2007)

Xie, Chun, Patel, Rahul, Wu, Tianfu, Zhu, Jiankun, Henry, Tamika, Bhaskarabhatla, Madhavi, ...

Previous studies have demonstrated that the NZM2410/NZW ‘z’ allele of Sle1 on telomeric murine chromosome 1 led to lymphoproliferative autoimmunity, when acting in concert with the FASlpr defect...

PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr (2007)

Xie, Chun, Patel, Rahul, Wu, Tianfu, Zhu, Jiankun, Henry, Tamika, Bhaskarabhatla, Madhavi, ...

Previous studies have demonstrated that the NZM2410/NZW ‘z’ allele of Sle1 on telomeric murine chromosome 1 led to lymphoproliferative autoimmunity, when acting in concert with the FASlpr defect...

PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr (2007)

Xie, Chun, Patel, Rahul, Wu, Tianfu, Zhu, Jiankun, Henry, Tamika, Bhaskarabhatla, Madhavi, ...

Previous studies have demonstrated that the NZM2410/NZW ‘z’ allele of Sle1 on telomeric murine chromosome 1 led to lymphoproliferative autoimmunity, when acting in concert with the FASlpr defect...

snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome (2006)

Yang, Jian-Hua, Zhang, Xiao-Chen, Huang, Zhan-Peng, Zhou, Hui, Huang, Mian-Bo, Zhang, Shu, ...

Small nucleolar RNAs (snoRNAs) represent an abundant group of non-coding RNAs in eukaryotes. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense...

snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome (2006)

Yang, Jian-Hua, Zhang, Xiao-Chen, Huang, Zhan-Peng, Zhou, Hui, Huang, Mian-Bo, Zhang, Shu, ...

Small nucleolar RNAs (snoRNAs) represent an abundant group of non-coding RNAs in eukaryotes. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense...

snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome (2006)

Yang, Jian-Hua, Zhang, Xiao-Chen, Huang, Zhan-Peng, Zhou, Hui, Huang, Mian-Bo, Zhang, Shu, ...

Small nucleolar RNAs (snoRNAs) represent an abundant group of non-coding RNAs in eukaryotes. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense...

snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome (2006)

Yang, Jian-Hua, Zhang, Xiao-Chen, Huang, Zhan-Peng, Zhou, Hui, Huang, Mian-Bo, Zhang, Shu, ...

Small nucleolar RNAs (snoRNAs) represent an abundant group of non-coding RNAs in eukaryotes. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense...

Spatial expression of germ cell markers during maturation of human fetal male gonads: an immunohistochemical study (2006)

Pauls, Katharina, Schorle, Hubert, Jeske, Wiebke, Brehm, Ralph, Steger, Klaus, Wernert, Nicolas, ...

BACKGROUND: The aim of the present study was to examine fetal male germ cells for expression of proteins associated with differentiation and maturation and to compare them with morphologically...

snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome (2006)

Yang, Jian-Hua, Zhang, Xiao-Chen, Huang, Zhan-Peng, Zhou, Hui, Huang, Mian-Bo, Zhang, Shu, ...

Small nucleolar RNAs (snoRNAs) represent an abundant group of non-coding RNAs in eukaryotes. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense...

snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome (2006)

Yang, Jian-Hua, Zhang, Xiao-Chen, Huang, Zhan-Peng, Zhou, Hui, Huang, Mian-Bo, Zhang, Shu, ...

Small nucleolar RNAs (snoRNAs) represent an abundant group of non-coding RNAs in eukaryotes. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense...

snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome (2006)

Yang, Jian-Hua, Zhang, Xiao-Chen, Huang, Zhan-Peng, Zhou, Hui, Huang, Mian-Bo, Zhang, Shu, ...

Small nucleolar RNAs (snoRNAs) represent an abundant group of non-coding RNAs in eukaryotes. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense...

Electron transfer reactivity and the catalytic activity of hemoglobin incorporated in dimethylaminoethyl methacrylate film (2005)

Zhou,Hui, Yang,Rongwu, Shang,Libin, Zhu,Zhiqiang, Li,Genxi

Hemoglobin (Hb) was incorporated in dimethylaminoethyl methacrylate (DMAEMA) to form a film and the film was modified on pyrolytic graphite (PG) electrode. UV-Vis spectra suggested that Hb in the...

[Study on the metabolic health risks of body mass index and waist circumference] (2005)

Guo, Zhi-Rong, Zhang, Jun, Sun, Guo-Xiang, Zhou, Zheng-Yuan, ...

OBJECTIVE: To evaluate the effect of body mass index (BMI) and waist circumference (WC) on metabolic health risks (MHR). METHODS: Based on data from two community populations (Suzhou city and...

Map Overlay (2005)

Zhou, Hui

In geographic information system, many objects on maps will be presented by bounding polygons or bounding rectangles. Intersection of objects on map will be formulated as finding intersection of...

Genome-wide analyses of two families of snoRNA genes from Drosophila melanogaster, demonstrating the extensive utilization of introns for coding of snoRNAs (2005)

HUANG, ZHAN-PENG, ZHOU, HUI, HE, HUA-LIANG, CHEN, CHUN-LONG, LIANG, DAN, QU, LIANG-HU

Small nucleolar RNAs (snoRNAs) are an abundant group of noncoding RNAs mainly involved in the post-transcriptional modifications of rRNAs in eukaryotes. In this study, a large-scale genome-wide...

Genome-wide analyses of two families of snoRNA genes from Drosophila melanogaster, demonstrating the extensive utilization of introns for coding of snoRNAs (2005)

HUANG, ZHAN-PENG, ZHOU, HUI, HE, HUA-LIANG, CHEN, CHUN-LONG, LIANG, DAN, QU, LIANG-HU

Small nucleolar RNAs (snoRNAs) are an abundant group of noncoding RNAs mainly involved in the post-transcriptional modifications of rRNAs in eukaryotes. In this study, a large-scale genome-wide...

A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes (2005)

Gu, Ai-Di, Zhou, Hui, Yu, Chun-Hong, Qu, Liang-Hu

Box H/ACA snoRNAs represent an abundant group of small non-coding RNAs mainly involved in the pseudouridylation of rRNAs and/or snRNAs in eukaryotes and Archaea. In this study, we describe a novel...

Mitogenomic Perspectives on the Origin and Phylogeny of Living Amphibians (2005)

Zhang, Peng, Zhou, Hui, Chen, Yue-Qin, Liu, Yi-Fei, Qu, Liang-Hu

Establishing the relationships among modern amphibians (lissamphibians) and their ancient relatives is necessary for our understanding of early tetrapod evolution. However, the phylogeny is still...

Study of Wet-Chemically-Prepared Hydrogen-Terminated Silicon (111) Surfaces and a Novel Implementation of a High-Resolution Interferometer (2004)

Zhou, Hui

This thesis summarizes my graduate study under the National Institute of Standards and Technology (NIST) Atom-Based Dimensional Metrology Project, in which we are developing methods for measuring...

Study of Wet-Chemically-Prepared Hydrogen-Terminated Silicon (111) Surfaces and a Novel Implementation of a High-Resolution Interferometer (2004)

Zhou, Hui

This thesis summarizes my graduate study under the National Institute of Standards and Technology (NIST) Atom-Based Dimensional Metrology Project, in which we are developing methods for measuring...

Sulphur By-Product: The Relationship between Volatile Sulphur Compounds and Dental Plaque-Induced Gingivitis (2004)

Hui Zhou, Gayle Bunger McCombs, Michele L. Darby, K. Marinak

The purpose of this study was to evaluate the relationship between volatile sulphur compounds (VSC) and gingival health status, and to monitor the changes in VSC in early dental plaque-induced...

Identification of 20 microRNAs from Oryza sativa (2004)

Wang, Jia-Fu, Zhou, Hui, Chen, Yue-Qin, Luo, Qing-Jun, Qu, Liang-Hu

MicroRNAs (miRNAs) are present in both plant and animal kingdoms and represents a growing family of non‐coding RNAs. These tiny RNAs act as small guides and direct negative regulations usually...

Adaptive radar clutter suppression / (2003)

Zhou, Hui.

Approved by: H.K. Hwang, James S. Kang and John Fang.

The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa (2003)

Chen, Chun-Long, Liang, Dan, Zhou, Hui, Zhuo, Min, Chen, Yue-Qin, Qu, Liang-Hu

Using a powerful computer‐assisted analysis strategy, a large‐scale search of small nucleolar RNA (snoRNA) genes in the recently released draft sequence of the rice genome was carried out....

A Macro-Micro Motion System for a Scanning Tunneling Microscope (2002)

James D. Gilsinn, Bradley N. Damazo, Richard Silver, Hui Zhou

As nano-lithography technology improves, more companies and research groups have the capability to create nano-scale structures. Scanning tunneling microscopes (STMs) are commonly used to create...

A novel gene organization: intronic snoRNA gene clusters from Oryza sativa (2002)

Liang, Dan, Zhou, Hui, Zhang, Peng, Chen, Yue-Qin, Chen, Xiao, Chen, Chun-Long, ...

Based on the analysis of structural features and conserved elements, 27 novel snoRNA genes have been identified from rice. All of them belong to the C/D box‐containing snoRNA family except...

The Schizosaccharomyces pombe mgU6-47 gene is required for 2'-O-methylation of U6 snRNA at A41 (2002)

Zhou, Hui, Chen, Yue-Qin, Du, Yan-Ping, Qu, Liang-Hu

Through a computer search of DNA databases, we have identified the homologs of the mgU6-47 snoRNA gene from the yeast Schizosaccharomyces pombe, the fly Drosophila melanogaster and human. The three...

Identification of antigenic escape variants in an immunodominant epitope of hepatitis C virus (1999)

Eckels, David D., Zhou, Hui, Bian, TongHua, Wang, Huiru

Numerous investigators have postulated that one mechanism by which hepatitis C virus (HCV) may evade the immune system is through the formation of escape mutants. This hypothesis is based largely on...

Call process handling in wireless access network /--by Hui Zhou. (1998)

Zhou, Hui.

Thesis (M.S. in Engin.)--University of Texas at Austin, 1998.

Dynamic analysis of a catalyst converter /--by Hui Zhou. (1992)

Zhou, Hui.

Thesis (M.S.)--University of Nebraska--Lincoln, 1992.

The Schizosaccharomyces pombe mgU6-47 gene is required for 2′-O-methylation of U6 snRNA at A41

Zhou, Hui, Chen, Yue-Qin, Du, Yan-Ping, Qu, Liang-Hu

Through a computer search of DNA databases, we have identified the homologs of the mgU6-47 snoRNA gene from the yeast Schizosaccharomyces pombe, the fly Drosophila melanogaster and human. The three...

Seven Novel Methylation Guide Small Nucleolar RNAs Are Processed from a Common Polycistronic Transcript by Rat1p and RNase III in Yeast

Qu, Liang-Hu, Henras, Anthony, Lu, Yong-Jun, Zhou, Hui, Zhou, Wei-xin, Zhu, Yuan-Qi, ...

Through a computer search of the genome of the yeast Saccharomyces cerevisiae, the coding sequences of seven different box C/D antisense small nucleolar RNAs (snoRNAs) with the structural hallmarks...

Interaction of Huntington Disease Protein with Transcriptional Activator Sp1

Li, Shi-Hua, Cheng, Anna L., Zhou, Hui, Lam, Suzanne, Rao, Manjula, Li, He, ...

Polyglutamine expansion causes Huntington disease (HD) and at least seven other neurodegenerative diseases. In HD, N-terminal fragments of huntingtin with an expanded glutamine tract are able to...

A novel gene organization: intronic snoRNA gene clusters from Oryza sativa

Liang, Dan, Zhou, Hui, Zhang, Peng, Chen, Yue-Qin, Chen, Xiao, Chen, Chun-Long, ...

Based on the analysis of structural features and conserved elements, 27 novel snoRNA genes have been identified from rice. All of them belong to the C/D box-containing snoRNA family except for one...

The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa

Chen, Chun-Long, Liang, Dan, Zhou, Hui, Zhuo, Min, Chen, Yue-Qin, Qu, Liang-Hu

Using a powerful computer-assisted analysis strategy, a large-scale search of small nucleolar RNA (snoRNA) genes in the recently released draft sequence of the rice genome was carried out. This...

Identification of 20 microRNAs from Oryza sativa

Wang, Jia-Fu, Zhou, Hui, Chen, Yue-Qin, Luo, Qing-Jun, Qu, Liang-Hu

MicroRNAs (miRNAs) are present in both plant and animal kingdoms and represents a growing family of non-coding RNAs. These tiny RNAs act as small guides and direct negative regulations usually in the...

Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing

Huang, Shengbing, Zhou, Hui, Katzmann, David, Hochstrasser, Mark, Atanasova, Elena, Zhang, Zhiguo

Epigenetic inheritance of heterochromatin structure is an important cellular process whose mechanism remains elusive. In this article, we describe the identification of nine enhancers of the...

A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes

Gu, Ai-Di, Zhou, Hui, Yu, Chun-Hong, Qu, Liang-Hu

Box H/ACA snoRNAs represent an abundant group of small non-coding RNAs mainly involved in the pseudouridylation of rRNAs and/or snRNAs in eukaryotes and Archaea. In this study, we describe a novel...

Genome-wide analyses of two families of snoRNA genes from Drosophila melanogaster, demonstrating the extensive utilization of introns for coding of snoRNAs

HUANG, ZHAN-PENG, ZHOU, HUI, HE, HUA-LIANG, CHEN, CHUN-LONG, LIANG, DAN, QU, LIANG-HU

Small nucleolar RNAs (snoRNAs) are an abundant group of noncoding RNAs mainly involved in the post-transcriptional modifications of rRNAs in eukaryotes. In this study, a large-scale genome-wide...

Phylogeny, evolution, and biogeography of Asiatic Salamanders (Hynobiidae)

Zhang, Peng, Chen, Yue-Qin, Zhou, Hui, Liu, Yi-Fei, Wang, Xiu-Ling, Papenfuss, Theodore J., ...

We sequenced 15 complete mitochondrial genomes and performed comprehensive molecular phylogenetic analyses to study the origin and phylogeny of the Hynobiidae, an ancient lineage of living...

snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome

Yang, Jian-Hua, Zhang, Xiao-Chen, Huang, Zhan-Peng, Zhou, Hui, Huang, Mian-Bo, Zhang, Shu, ...

Small nucleolar RNAs (snoRNAs) represent an abundant group of non-coding RNAs in eukaryotes. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense...

The Schizosaccharomyces pombe mgU6-47 gene is required for 2′-O-methylation of U6 snRNA at A41

Zhou, Hui, Chen, Yue-Qin, Du, Yan-Ping, Qu, Liang-Hu

Through a computer search of DNA databases, we have identified the homologs of the mgU6-47 snoRNA gene from the yeast Schizosaccharomyces pombe, the fly Drosophila melanogaster and human. The three...

Seven Novel Methylation Guide Small Nucleolar RNAs Are Processed from a Common Polycistronic Transcript by Rat1p and RNase III in Yeast

Qu, Liang-Hu, Henras, Anthony, Lu, Yong-Jun, Zhou, Hui, Zhou, Wei-xin, Zhu, Yuan-Qi, ...

Through a computer search of the genome of the yeast Saccharomyces cerevisiae, the coding sequences of seven different box C/D antisense small nucleolar RNAs (snoRNAs) with the structural hallmarks...

Interaction of Huntington Disease Protein with Transcriptional Activator Sp1

Li, Shi-Hua, Cheng, Anna L., Zhou, Hui, Lam, Suzanne, Rao, Manjula, Li, He, ...

Polyglutamine expansion causes Huntington disease (HD) and at least seven other neurodegenerative diseases. In HD, N-terminal fragments of huntingtin with an expanded glutamine tract are able to...

A novel gene organization: intronic snoRNA gene clusters from Oryza sativa

Liang, Dan, Zhou, Hui, Zhang, Peng, Chen, Yue-Qin, Chen, Xiao, Chen, Chun-Long, ...

Based on the analysis of structural features and conserved elements, 27 novel snoRNA genes have been identified from rice. All of them belong to the C/D box-containing snoRNA family except for one...

The high diversity of snoRNAs in plants: identification and comparative study of 120 snoRNA genes from Oryza sativa

Chen, Chun-Long, Liang, Dan, Zhou, Hui, Zhuo, Min, Chen, Yue-Qin, Qu, Liang-Hu

Using a powerful computer-assisted analysis strategy, a large-scale search of small nucleolar RNA (snoRNA) genes in the recently released draft sequence of the rice genome was carried out. This...

Identification of 20 microRNAs from Oryza sativa

Wang, Jia-Fu, Zhou, Hui, Chen, Yue-Qin, Luo, Qing-Jun, Qu, Liang-Hu

MicroRNAs (miRNAs) are present in both plant and animal kingdoms and represents a growing family of non-coding RNAs. These tiny RNAs act as small guides and direct negative regulations usually in the...

Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing

Huang, Shengbing, Zhou, Hui, Katzmann, David, Hochstrasser, Mark, Atanasova, Elena, Zhang, Zhiguo

Epigenetic inheritance of heterochromatin structure is an important cellular process whose mechanism remains elusive. In this article, we describe the identification of nine enhancers of the...

A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes

Gu, Ai-Di, Zhou, Hui, Yu, Chun-Hong, Qu, Liang-Hu

Box H/ACA snoRNAs represent an abundant group of small non-coding RNAs mainly involved in the pseudouridylation of rRNAs and/or snRNAs in eukaryotes and Archaea. In this study, we describe a novel...

Genome-wide analyses of two families of snoRNA genes from Drosophila melanogaster, demonstrating the extensive utilization of introns for coding of snoRNAs

HUANG, ZHAN-PENG, ZHOU, HUI, HE, HUA-LIANG, CHEN, CHUN-LONG, LIANG, DAN, QU, LIANG-HU

Small nucleolar RNAs (snoRNAs) are an abundant group of noncoding RNAs mainly involved in the post-transcriptional modifications of rRNAs in eukaryotes. In this study, a large-scale genome-wide...

Phylogeny, evolution, and biogeography of Asiatic Salamanders (Hynobiidae)

Zhang, Peng, Chen, Yue-Qin, Zhou, Hui, Liu, Yi-Fei, Wang, Xiu-Ling, Papenfuss, Theodore J., ...

We sequenced 15 complete mitochondrial genomes and performed comprehensive molecular phylogenetic analyses to study the origin and phylogeny of the Hynobiidae, an ancient lineage of living...

snoSeeker: an advanced computational package for screening of guide and orphan snoRNA genes in the human genome

Yang, Jian-Hua, Zhang, Xiao-Chen, Huang, Zhan-Peng, Zhou, Hui, Huang, Mian-Bo, Zhang, Shu, ...

Small nucleolar RNAs (snoRNAs) represent an abundant group of non-coding RNAs in eukaryotes. They can be divided into guide and orphan snoRNAs according to the presence or absence of antisense...

O-Mannosyltransferase 1 in Aspergillus fumigatus (AfPmt1p) Is Crucial for Cell Wall Integrity and Conidium Morphology, Especially at an Elevated Temperature▿

Zhou, Hui, Hu, Hongyan, Zhang, Lijuan, Li, Ruoyu, Ouyang, Haomiao, Ming, Jia, ...

Protein O-mannosyltransferases initiate O mannosylation of secretory proteins, which are of fundamental importance in eukaryotes. In this study, the PMT gene family of the human fungal pathogen...

A novel role for histone chaperones CAF-1 and Rtt106p in heterochromatin silencing

Huang, Shengbing, Zhou, Hui, Tarara, Jim, Zhang, Zhiguo

The histone chaperones CAF-1 and Rtt106p are required for heterochromatin silencing in the yeast Saccharomyces cerevisiae. Although it has been suggested that CAF-1 is involved in the maintenance of...

Huntingtin forms toxic NH2-terminal fragment complexes that are promoted by the age-dependent decrease in proteasome activity

Zhou, Hui, Cao, Fengli, Wang, Zhishan, Yu, Zhao-Xue, Nguyen, Huu-Phuc, Evans, Joy, ...

Although NH2-terminal mutant huntingtin (htt) fragments cause neurological disorders in Huntington's disease (HD), it is unclear how toxic htt fragments are generated and contribute to the disease...

The SNPlex Genotyping System: A Flexible and Scalable Platform for SNP Genotyping

Tobler, Andreas R., Short, Sabine, Andersen, Mark R., Paner, Teodoro M., Briggs, Jason C., Lambert, Stephen M., ...

We developed the SNPlex Genotyping System to address the need for accurate genotyping data, high sample throughput, study design flexibility, and cost efficiency. The system uses oligonucleotide...

Genomewide Analysis of Box C/D and Box H/ACA snoRNAs in Chlamydomonas reinhardtii Reveals an Extensive Organization Into Intronic Gene Clusters

Chen, Chun-Long, Chen, Chong-Jian, Vallon, Olivier, Huang, Zhan-Peng, Zhou, Hui, Qu, Liang-Hu

Chlamydomonas reinhardtii is a unicellular green alga, the lineage of which diverged from that of land plants >1 billion years ago. Using the powerful small nucleolar RNA (snoRNA) mining platform to...

Mitochondrial DNA Evidence for a Diversified Origin of Workers Building Mausoleum for First Emperor of China

Xu, Zhi, Zhang, Fan, Xu, Bosong, Tan, Jingze, Li, Shilin, Li, Chunxiang, ...

Variant studies on ancient DNA have attempted to reveal individual origin. Here, based on cloning sequencing and polymerase chain reaction-restriction fragment length polymorphisms, we analyzed...

Tribendimidine and Albendazole for Treating Soil-Transmitted Helminths, Strongyloides stercoralis and Taenia spp.: Open-Label Randomized Trial

Steinmann, Peter, Zhou, Xiao-Nong, Du, Zun-Wei, Jiang, Jin-Yong, Xiao, Shu-Hua, Wu, Zhong-Xing, ...

More than a billion people are infected with intestinal worms and, in the developing world, many individuals harbor several kinds of worms concurrently. There are only a handful of drugs available...

A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae

Zhou, Hui, Zhan, Jixun, Watanabe, Kenji, Xie, Xinkai, Tang, Yi

Resorcylic acid lactones represent a unique class of fungal polyketides and display a wide range of biological activities, such as nanomolar inhibitors of Hsp90 and MAP kinase. The biosynthesis of...

Stress-induced tRNA-derived RNAs: a novel class of small RNAs in the primitive eukaryote Giardia lamblia

Li, Yan, Luo, Jun, Zhou, Hui, Liao, Jian-You, Ma, Li-Ming, Chen, Yue-Qin, ...

Giardia lamblia is an early diverging and evolutionarily successful protozoan as it can enter into a dormant cyst stage from a vegetative trophozoite. During dormant stage, its metabolic rate...

Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin

Wang, Chuan-En, Zhou, Hui, McGuire, John R., Cerullo, Vincenzo, Lee, Brendan, Li, Shi-Hua, ...

Mutant huntingtin accumulates in the neuronal nuclei and processes, which suggests that its subcellular localization is critical for the pathology of Huntington's disease (HD). However, the...

Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP

Ni, Min, Zhou, Hui, Wey, Shiuan, Baumeister, Peter, Lee, Amy S.

The unfolded protein response (UPR) is an evolutionarily conserved mechanism to allow cells to adapt to stress targeting the endoplasmic reticulum (ER). Induction of ER chaperone GRP78/BiP increases...

Genome-wide evolutionary analysis of the noncoding RNA genes and noncoding DNA of Paramecium tetraurelia

Chen, Chun-Long, Zhou, Hui, Liao, Jian-You, Qu, Liang-Hu, Amar, Laurence

The compact genome of the unicellular eukaryote Paramecium tetraurelia contains noncoding DNA (ncDNA) distributed into >39,000 intergenic sequences and >90,000 introns of 390 base pairs (bp) and 25...

The Elongator Complex Interacts with PCNA and Modulates Transcriptional Silencing and Sensitivity to DNA Damage Agents

Li, Qing, Fazly, A. M., Zhou, Hui, Huang, Shengbing, Zhang, Zhiguo, Stillman, Bruce

Histone chaperones CAF-1 and Asf1 function to deposit newly synthesized histones onto replicating DNA to promote nucleosome formation in a proliferating cell nuclear antigen (PCNA) dependent process....

Structural Characterization of an Oligosaccharide Made by Neisseria sicca ▿

O'Connor, Ellen T., Zhou, Hui, Bullock, Kevin, Swanson, Karen V., Griffiss, J. McLeod, Reinhold, Vernon N., ...

Neisseria sicca 4320 expresses two carbohydrate-containing components with sodium dodecyl sulfate-polyacrylamide gel electrophoresis mobilities that resemble those of lipooligosaccharide and...