Huiyong Yin

Quantification of Isoprostanes as an Index of Oxidative Stress: A Update (2006)

Huiyong Yin, Erik S. Musiek, Jason D. Morrow

Isoprostanes are prostaglandin-like compounds formed from the free radical-catalyzed peroxidation of arachidonic acid independent of the cyclooxygenase enzymes. The isoprostanes possess potent...

Quantification of Isoprostanes as an Index of Oxidative Stress: A Update (2006)

Huiyong Yin, Erik S. Musiek, Jason D. Morrow

Isoprostanes are prostaglandin-like compounds formed from the free radical-catalyzed peroxidation of arachidonic acid independent of the cyclooxygenase enzymes. The isoprostanes possess potent...

Inhibition of 11β–hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans

Zhang, Ming-Zhi, Xu, Jie, Yao, Bing, Yin, Huiyong, Cai, Qiuyin, Shrubsole, Martha J., ...

Colorectal cancer (CRC) is a leading cause of cancer death, yet primary prevention remains the best approach to reducing overall morbidity and mortality. Studies have shown that COX-2–derived PGE2...

F2-Dihomo-isoprostanes arise from free radical attack on adrenic acid*

VanRollins, Mike, Woltjer, Randall L., Yin, Huiyong, Morrow, Jason D., Montine, Thomas J.

Unlike F4-neuroprostanes (F4-NeuroPs), which are relatively selective in vivo markers of oxidative damage to neuronal membranes, there currently is no method to assess the extent of free radical...

Formation of Highly Reactive Cyclopentenone Isoprostane Compounds (A3/J3-Isoprostanes) in Vivo from Eicosapentaenoic Acid*

Brooks, Joshua D., Milne, Ginger L., Yin, Huiyong, Sanchez, Stephanie C., Porter, Ned A., Morrow, Jason D.

Omega-3 (ω-3) polyunsaturated fatty acids (PUFAs) found in marine fish oils are known to suppress inflammation associated with a wide variety of diseases. Eicosapentaenoic acid (EPA) is one of the...