Huy N. Hoang

Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus (2006)

Shepherd, Nicholas E., Hoang, Huy N., Desai, Vishal S., Letouze, Eric, Young, Paul R., Fairlie, David P.

A 13-residue peptide sequence from a respiratory syncitial virus fusion protein was constrained in an alpha-helical conformation by fusing two back-to-back cyclic alpha-turn mimetics. The resulting...

Metal Clips Induce Folding of a Short Unstructured Peptide into an -Helix via Turn Conformations in Water. Kinetic versus Thermodynamic Products (2004)

Renee L. Beyer, Huy N. Hoang, Trevor G. Appleton, David P. Fairlie

This paper showed that overlapping metal clips induces strong helicity in a short peptide in water.

Alpha -Turn Mimetics: Short Peptide -Helices Composed of Cyclic Metallopentapeptide Modules (2004)

Michael J. Kelso, Rene´e L. Beyer, Huy N. Hoang, Ami S. Lakdawala, J.P. Snyder, Oliver, W.V, ...

This paper explored the effect of multiple metal clips on peptide conformation. I am associate supervisor for R. Beyer’s PhD project. This paper was submitted in collaboration with J. Snyder of...

Alpha-Turn Mimetics: Short Peptide -Helices Composed of Cyclic Metallopentapeptide Modules (2004)

Michael J. Kelso, Renée L. Beyer, Huy N. Hoang, Ami S. Lakdawala, James P. Snyder, Warren V. Oliver, ...

Interfering with protein-protein binding is the mode of action of many existing drugs and is a potential mechanistic target in the design of new drugs. Small molecule peptidomimetics are potential...

Alpha -Turn Mimetics: Short Peptide -Helices Composed of Cyclic Metallopentapeptide Modules (2004)

Michael J. Kelso, Rene´e L. Beyer, Huy N. Hoang, Ami S. Lakdawala, J.P. Snyder, Oliver, W.V, ...

This paper explored the effect of multiple metal clips on peptide conformation. I am associate supervisor for R. Beyer’s PhD project. This paper was submitted in collaboration with J. Snyder of...

Metal Clips Induce Folding of a Short Unstructured Peptide into an -Helix via Turn Conformations in Water. Kinetic versus Thermodynamic Products (2004)

Renee L. Beyer, Huy N. Hoang, Trevor G. Appleton, David P. Fairlie

This paper showed that overlapping metal clips induces strong helicity in a short peptide in water.

Alpha-Turn Mimetics: Short Peptide -Helices Composed of Cyclic Metallopentapeptide Modules (2004)

Michael J. Kelso, Renée L. Beyer, Huy N. Hoang, Ami S. Lakdawala, James P. Snyder, Warren V. Oliver, ...

Interfering with protein-protein binding is the mode of action of many existing drugs and is a potential mechanistic target in the design of new drugs. Small molecule peptidomimetics are potential...

A Cyclic Metallopeptide Induces alpha-helicity in short peptide fragments of thermolysin (2003)

Michael J. Kelso, Huy N. Hoang, Warren Oliver, Nikolai Sokolenko, Darren R. March, Trevor Appleton, ...

This paper (and the next two listed) results from collaboration between myself and David Fairlie in IMB on the use of “metal clips” in folding short peptides. Following our initial paper in this...

A Cyclic Metallopeptide Induces alpha-helicity in short peptide fragments of thermolysin (2003)

Michael J. Kelso, Huy N. Hoang, Warren Oliver, Nikolai Sokolenko, Darren R. March, Trevor Appleton, ...

This paper (and the next two listed) results from collaboration between myself and David Fairlie in IMB on the use of “metal clips” in folding short peptides. Following our initial paper in this...