Huynh-Hoa Bui

ElliPro: a new structure-based tool for the prediction of antibody epitopes (2008)

Ponomarenko, Julia, Bui, Huynh-Hoa, Li, Wei, Fusseder, Nicholas, Bourne, Philip E, Sette, Alessandro, ...

Abstract Background Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between antigenicity,...

DOI 10.1007/s00251-005-0803-5 ORIGINAL PAPER (2008)

Bjoern Peters, John Sidney, Phil Bourne, Huynh-hoa Bui, Soeren Buus, David Nemazee, ...

The design and implementation of the immune epitope database and analysis resource

Immune epitope database analysis resource (IEDB-AR) (2008)

Zhang, Qing, Wang, Peng, Kim, Yohan, Haste-Andersen, Pernille, Beaver, John, Bourne, Philip E., ...

We present a new release of the immune epitope database analysis resource (IEDB-AR, http://tools.immuneepitope.org), a repository of web-based tools for the prediction and analysis of immune...

An analysis of the epitope knowledge related to Mycobacteria (2007)

Blythe, Martin J, Zhang, Qing, Vaughan, Kerrie, De Castro, Romulo, Salimi, Nima, Bui, Huynh-Hoa, ...

Abstract Background Tuberculosis, caused by the bacterium Mycobacterium tuberculosis , remains a leading cause of infectious disease morbidity and mortality, and is responsible for more than 2...

Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines (2007)

Bui, Huynh-Hoa, Sidney, John, Li, Wei, Fusseder, Nicolas, Sette, Alessandro

Abstract Background In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epitopes derived...

Protein sequence database for pathogenic arenaviruses (2007)

Bui, Huynh-Hoa, Botten, Jason, Fusseder, Nicolas, Pasquetto, Valerie, Mothe, Bianca, Buchmeier, Michael J, ...

Abstract Background Arenaviruses are a family of rodent-borne viruses that cause several hemorrhagic fevers. These diseases can be devastating and are often lethal. Herein, to aid in the design and...

Curation of complex, context-dependent immunological data (2006)

Vita, Randi, Vaughan, Kerrie, Zarebski, Laura, Salimi, Nima, Fleri, Ward, Grey, Howard, ...

Abstract Background The Immune Epitope Database and Analysis Resource (IEDB) is dedicated to capturing, housing and analyzing complex immune epitope related data http://www.immuneepitope.org ....

A Community Resource Benchmarking Predictions of Peptide Binding to MHC-I Molecules (2006)

Bjoern Peters, Huynh-Hoa Bui, Sune Frankild, Morten Nielsen, Claus Lundegaard, Emrah Kostem, ...

Recognition of peptides bound to major histocompatibility complex (MHC) class I molecules by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a characteristic peptide...

A Community Resource Benchmarking Predictions of Peptide Binding to MHC-I Molecules (2006)

Bjoern Peters, Huynh-Hoa Bui, Sune Frankild, Morten Nielsen, Claus Lundegaard, Emrah Kostem, ...

Recognition of peptides bound to MHC class I molecules by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a characteristic peptide binding preference, which can be...

Predicting population coverage of T-cell epitope-based diagnostics and vaccines (2006)

Bui, Huynh-Hoa, Sidney, John, Dinh, Kenny, Southwood, Scott, Newman, Mark J, Sette, Alessandro

Abstract Background T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a response...

BMC Bioinformatics BioMed Central Database Curation of complex, context-dependent immunological data (2006)

I Vita, Kerrie Vaughan, Laura Zarebski, Nima Salimi, Ward Fleri, Howard Grey, ...

© 2006 Vita et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License

An ontology for immune epitopes: application to the design of a broad scope database of immune reactivities (2005)

Sathiamurthy, Muthuraman, Peters, Bjoern, Bui, Huynh-Hoa, Sidney, John, Mokili, John, Wilson, Stephen S, ...

Abstract Background Epitopes can be defined as the molecular structures bound by specific receptors, which are recognized during immune responses. The Immune Epitope Database and Analysis Resource...

The Immune Epitope Database and Analysis Resource: From Vision to Blueprint (2005)

Bjoern Peters, John Sidney, Phil Bourne, Huynh-Hoa Bui, Soeren Buus, Grace Doh, ...

A planned repository of immune epitope data with associated analysis tools should be a boon to vaccine development.

HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

Oseroff, Carla, Kos, Ferdynand, Bui, Huynh-Hoa, Peters, Bjoern, Pasquetto, Valerie, Glenn, Jean, ...

We have analyzed by ex vivo ELISPOT the anti-vaccinia cytotoxic T lymphocyte responses of peripheral blood mononuclear cells from humans vaccinated with Dryvax vaccine. More than 6,000 peptides from...

The Immune Epitope Database and Analysis Resource: From Vision to Blueprint

Peters, Bjoern, Sidney, John, Bourne, Phil, Bui, Huynh-Hoa, Buus, Soeren, Doh, Grace, ...

A planned repository of immune epitope data with associated analysis tools should be a boon to vaccine development

A Community Resource Benchmarking Predictions of Peptide Binding to MHC-I Molecules

Peters, Bjoern, Bui, Huynh-Hoa, Frankild, Sune, Nielsen, Morten, Lundegaard, Claus, Kostem, Emrah, ...

Recognition of peptides bound to major histocompatibility complex (MHC) class I molecules by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a characteristic peptide...

The Immune Epitope Database and Analysis Resource: From Vision to Blueprint

Peters, Bjoern, Sidney, John, Bourne, Phil, Bui, Huynh-Hoa, Buus, Soeren, Doh, Grace, ...

A planned repository of immune epitope data with associated analysis tools should be a boon to vaccine development

HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

Oseroff, Carla, Kos, Ferdynand, Bui, Huynh-Hoa, Peters, Bjoern, Pasquetto, Valerie, Glenn, Jean, ...

We have analyzed by ex vivo ELISPOT the anti-vaccinia cytotoxic T lymphocyte responses of peripheral blood mononuclear cells from humans vaccinated with Dryvax vaccine. More than 6,000 peptides from...

A Community Resource Benchmarking Predictions of Peptide Binding to MHC-I Molecules

Peters, Bjoern, Bui, Huynh-Hoa, Frankild, Sune, Nielsen, Morten, Lundegaard, Claus, Kostem, Emrah, ...

Recognition of peptides bound to major histocompatibility complex (MHC) class I molecules by T lymphocytes is an essential part of immune surveillance. Each MHC allele has a characteristic peptide...

HLA-A2-Restricted Protection against Lethal Lymphocytic Choriomeningitis▿ †

Botten, Jason, Whitton, J. Lindsay, Barrowman, Polly, Sidney, John, Whitmire, Jason K., Alexander, Jeff, ...

The consequences of human lymphocytic choriomeningitis virus (LCMV) infection can be severe, including aseptic meningitis in immunocompetent individuals, hydrocephalus or chorioretinitis in fetal...

Ab and T cell epitopes of influenza A virus, knowledge and opportunities

Bui, Huynh-Hoa, Peters, Bjoern, Assarsson, Erika, Mbawuike, Innocent, Sette, Alessandro

The Immune Epitope Database and Analysis Resources (IEDB) (www.immuneepitope.org) was recently developed to capture epitope related data. IEDB also hosts various bioinformatics tools that can be used...

Immune epitope database analysis resource (IEDB-AR)

Zhang, Qing, Wang, Peng, Kim, Yohan, Haste-Andersen, Pernille, Beaver, John, Bourne, Philip E., ...

We present a new release of the immune epitope database analysis resource (IEDB-AR, http://tools.immuneepitope.org), a repository of web-based tools for the prediction and analysis of immune...

Immunomic Analysis of the Repertoire of T-Cell Specificities for Influenza A Virus in Humans ▿ † ‡

Assarsson, Erika, Bui, Huynh-Hoa, Sidney, John, Zhang, Qing, Glenn, Jean, Oseroff, Carla, ...

Continuing antigenic drift allows influenza viruses to escape antibody-mediated recognition, and as a consequence, the vaccine currently in use needs to be altered annually. Highly conserved epitopes...