Hylan C. Moises

Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects (2006)

Walker, J. Michael, Moises, Hylan C., Coy, David H., Young, Elizabeth A., Watson, Stanley J., Akil, Huda

Dynorphin and an opiate-inactive fragment des-Tyr-dynorphin produced similar effects on EEG, motor function and hippocampal unit firing. Naloxone had no effect on the actions of dynorphin in these...

Multiple effects of long-term morphine treatment on postsynaptic [beta]-adrenergic receptor function in hippocampus: an intracellular analysis (1994)

Ackerman, Janice M., Womble, Mark D., Moises, Hylan C.

We previously reported that [beta]-adrenergic receptors are increased in cerebral cortex and hippocampus in rats treated chronically with morphine and subsequently down-regulated after morphine...

Metabotropic glutamate receptor agonist ACPD inhibits some, but not all, muscarinic-sensitive K + conductances in basolateral amygdaloid neurons (1994)

Womble, Mark D., Moises, Hylan C.

Muscarinic agonists produce membrane depolarization and losses of spike frequency accommodation and the slow afterhyperpolarization (AHP) when applied to neurons of the basolateral amygdala (BLA)....

Muscarinic modulation of conductances underlying the afterhyperpolarization in neurons of the rat basolateral amygdala (1993)

Womble, Mark D., Moises, Hylan C.

The excitability level of pyramidal neurons in the basolateral amygdala (BLA) is greatly increased following muscarinic receptor activation, an effect associated with an increased rate of action...

Inhibitory responses of rat basolateral amygdaloid neurons recorded in vitro (1992)

Washburn, M. S., Moises, Hylan C.

The purpose of the present study was to characterize the ionic and pharmacological basis of the actions of synaptically released and exogenously applied GABA in basolateral amygdaloid pyramidal cells...

Electrophysiological actions of VIP in rat somatosensory cortex (1991)

Sessler, Francis M., Grady, Steve M., Waterhouse, Barry D., Moises, Hylan C.

Electrophysiological and biochemical studies suggest that VIP may exert a facilitating action in the neocortical local circuitry. In the present study, we examined the actions of VIP and VIP +...

Potassium activation of the Na,K-pump in isolated brain microvessels and synaptosomes (1990)

Schielke, Gerald P., Moises, Hylan C., Lorris Betz, A.

Brain capillary endothelial cells play an important role in ion homeostasis of the brain through the transendothelial transport of Na and K. Since little is known about the regulation of ion...

Modification of the visual response properties of cerebellar neurons by norepinephrine (1990)

Moises, Hylan C., Burne, Richard A., Woodward, Donald J.

Extracellular recordings were conducted in the paraflocculus of anesthetized Long-Evans pigmented rats to determine how iontophoresis of norepinephrine (NE) affects the responsiveness of individual...

Electrophysiological responsiveness to isoproterenol in rat hippocampal slices correlates with changes in [beta]-adrenergic receptor density induced by chronic morphine treatment (1989)

Moises, Hylan C., Smith, Charles B.

The effects of chronic morphine treatment and morphine withdrawal on [beta]-adrenergic receptor density and electrophysiological responsiveness in rat hippocampus were examined. Chronic treatment of...

Changes in [alpha]-adrenoceptor number and function in brains of morphine-dependent rats (1989)

Smith, Charles B., Moises, Hylan C., Spengler, Robert N., Hollingsworth, Peggie J.

The effects of long-term treatment of rats with morphine sulfate were assessed upon the specific binding of [3H]clonidine to [alpha]2-adrenoceptors on neural membranes isolated from various brain...

Electrophysiological correlates of presynaptic opiate receptor activation: reduction in norepinephrine-mediated inhibition from the locus coeruleus (1987)

Moises, Hylan C.

Inhibitory responses of rat cerebellar Purkinje cells to locus coeruleus (LC) stimulation and iontophoresis of norepinephrine (NE) were examined before and after administration of morphine to...

Adrenergic responses of baroreceptive cells in the nucleus tractus solitarii of the rat: a microiontophoretic study (1987)

Feldman, Peter D., Moises, Hylan C.

Anatomical and pharmacological evidence suggests a role for catecholamines (CAs) in the modulation of the baroreceptor reflex within the nucleus tractus solitarii (NTS). Single neurons in the NTS of...

Changes in cortical [beta]-adrenergic receptor density and neuronal sensitivity to norepinephrine accompany morphine dependence and withdrawal (1987)

Moises, Hylan C., Smith, Charles B.

Radioligand binding experiments were carried out in conjunction with electrophysiological recordings in vivo in the parietal cortex in rats to assess changes in postsynaptic [beta]-adrenergic...

Electrophysiological effects of dynorphin peptides on hippocampal pyramidal cells in rat (1985)

Moises, Hylan C., Michael Walker, J.

Single-unit extracellular recording was carried out in rats to characterize the effects of dynorphin and several structurally related peptides on hippocampal pyramidal cell activity. Dynorphin,...

Changes occur in central adrenoreceptor function following long-term morphine treatment and during morphine withdrawal (1984)

Moises, Hylan C., Smith, Charles B.

Radioloigand binding techniques were used in combination with electrophysiological recording to characterize changes in beta adrenoreceptor activity in various brain areas in rats treated chronically...

Changes in alpha2 adrenoreceptors in various areas of the rat brain after long-term administration of "mu" and "kappa" opiate agonists (1983)

Smith, Charles B., Hollingsworth, Peggie J., Geer, Joann J., Moises, Hylan C.

Clonidine, an alpha2 adrenoreceptor agonist, is used to treat opiate dependent individuals who are experiencing the signs and symptoms of withdrawal. Changes in the apparent number of alpha2...

Prolactin-releasing peptide affects gastric motor function in rat by modulating synaptic transmission in the dorsal vagal complex

Grabauskas, Gintautas, Zhou, Shi-Yi, Das, Sudipto, Lu, Yuanxu, Owyang, Chung, Moises, Hylan C

Prolactin-releasing peptide (PrRP) is a recently discovered neuropeptide implicated in the central control of feeding behaviour and autonomic homeostasis. PrRP-containing neurones and PrRP receptor...

Ca2+ and frequency dependence of exocytosis in isolated somata of magnocellular supraoptic neurones of the rat hypothalamus

Soldo, Brandi L, Giovannucci, David R, Stuenkel, Edward L, Moises, Hylan C

In addition to action potential-evoked exocytotic release at neurohypophysial nerve terminals, the neurohormones arginine vasopressin (aVP) and oxytocin (OT) undergo Ca2+-dependent somatodendritic...

Ca2+ and frequency dependence of exocytosis in isolated somata of magnocellular supraoptic neurones of the rat hypothalamus

Soldo, Brandi L, Giovannucci, David R, Stuenkel, Edward L, Moises, Hylan C

In addition to action potential-evoked exocytotic release at neurohypophysial nerve terminals, the neurohormones arginine vasopressin (aVP) and oxytocin (OT) undergo Ca2+-dependent somatodendritic...

Prolactin-releasing peptide affects gastric motor function in rat by modulating synaptic transmission in the dorsal vagal complex

Grabauskas, Gintautas, Zhou, Shi-Yi, Das, Sudipto, Lu, Yuanxu, Owyang, Chung, Moises, Hylan C

Prolactin-releasing peptide (PrRP) is a recently discovered neuropeptide implicated in the central control of feeding behaviour and autonomic homeostasis. PrRP-containing neurones and PrRP receptor...

μ-Opioid receptor activation inhibits N- and P-type Ca2+ channel currents in magnocellular neurones of the rat supraoptic nucleus

Soldo, Brandi L, Moises, Hylan C

The whole-cell voltage-clamp technique was used to examine opioid regulation of Ba2+ currents (IBa) through voltage-sensitive Ca2+ channels in isolated magnocellular supraoptic neurones (MNCs). The...

Gastrointestinal-projecting neurones in the dorsal motor nucleus of the vagus exhibit direct and viscerotopically organized sensitivity to orexin

Grabauskas, Gintautas, Moises, Hylan C

Orexin (hypocretin)-containing projections from lateral hypothalamus (LH) are thought to play an important role in the regulation of feeding behaviour and energy balance. In rodent studies, central...