Jennifer H. Cheeseman, Nyssa A. Levy, Pete Kaiser, Hyun S. Lillehoj, Susan J. Lamont
To understand better the events in early avian host immune responses to Salmonella Enteritidis (SE), we examined messenger-RNA (mRNA) expression for eight genes: CXCLi1[K60], CXCLi2 [IL-8/CAF],...
Antimicrobial Activity of Chicken NK-Lysin Against Eimeria Sporozoites (2008)
Yeong H. Hong, Hyun S. Lillehoj, Gregory R. Siragusa, Douglas D. Bannerman, Erik P. Lillehoj
NK-lysin is an antimicrobial and antitumor polypeptide that is considered to play an important role in innate immunity. Chicken NK-lysin is a member of the saposin-like protein family and exhibits...
Antimicrobial Activity of Chicken NK-Lysin Against Eimeria Sporozoites (2008)
Yeong H. Hong, Hyun S. Lillehoj, Gregory R. Siragusa, Douglas D. Bannerman, Erik P. Lillehoj
Soon S. Park, Hyun S. Lillehoj, Patricia C. Allen, Dong Woon Park, Steve FitzCoy, Daniel A. Bautista, ...
The incidence of necrotic enteritis (NE) due to Clostridium perfringens (CP) infection in commercial poultry has been increasing at an alarming rate. Although pre-exposure of chickens to coccidia...
Soon S. Park, Hyun S. Lillehoj, Patricia C. Allen, Dong Woon Park, Steve FitzCoy, Daniel A. Bautista, ...
EXPRESSION OF FLOTILLIN-1 ON EIMERIA TENELLA SPOROZOITES AND ITS ROLE IN HOST CELL INVASION (2007)
Emilio Del Cacho, Margarita Gallego, Caridad Sánchez-Acedo, Hyun S. Lillehoj
Hyun S. Lillehoj, Xicheng Ding, Rami A. Dalloul, Takanori Sato, Atsushi Yasuda, Erik P. Lillehoj
Avian coccidiosis is an intestinal disease caused by protozoa of the genus Eimeria. To investigate the potential of recombinant protein vaccines to control coccidiosis, we cloned 2 Eimeria sp. genes...
Recent Advances in Immunomodulation and Vaccination Strategies Against Coccidiosis (2005)
Rami A. Dalloul, Hyun S. Lillehoj
Coccidiosis is a ubiquitous intestinal protozoan infection of poultry seriously impairing the growth and feed utilization of infected animals. Conventional disease control strategies rely heavily on...
Hyun S. Lillehoj, Xicheng Ding, Marco A. Quiroz, Erich Bevensee, Erik P. Lillehoj
A cloned Eimeria acervulina gene (3-1E) was used to vaccinate chickens in ovo against coccidiosis, both alone and in combination with genes encoding interleukin (IL)-1, IL-2, IL-6, IL-8, IL-15,...
In Vivo Effects of CpG Oligodeoxynucleotide on Eimeria Infection in Chickens (2004)
Rami A. Dalloul, Hyun S. Lillehoj, Masashi Okamura, Hang Xie, Wongi Min, Xicheng Ding, ...
Poultry coccidiosis is the major parasitic disease of poultry and, until now, no recombinant vaccine has been developed. Short oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs (CpG...
Hyun S. Lillehoj, Guangxing Li
Nitric oxide (NO) is an important mediator of innate and acquired immunities. In the studies reported here, we quantified NO produced in vitro by chicken leukocytes and macrophages and in vivo during...
Rami A. Dalloul, Hyun S. Lillehoj, Timothy A. Shellem, John A. Doerr
SUMMARY. In a 2 × 2 factorial study, a broiler starter ration was amended for vitamin A (control, C; deficient, A) and probiotic status (−, P) to investigate their modulatory effects on the host...
Tadashi Miyamoto, Wongi Min, Hyun S. Lillehoj
SUMMARY. The application of a tetrazolium salt, WST-8, 2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H tetrazolium, monosodium salt to the lymphocyte proliferation assay in the...
Interleukin-2 Production in SC and TK Chickens Infected with Eimeria tenella (2002)
Guangxing Li, Erik P. Lillehoj, Hyun S. Lillehoj
SUMMARY. SC and TK inbred chicken strains display differential protective immunity to coccidiosis, SC being more resistant and TK susceptible to disease. In this study, the association between...
Yun, Cheol H., Lillehoj, Hyun S., Choi, Kang D.
The role of intestinal lymphocytes and gamma interferon (IFN-γ) production in protective immunity to Eimeria tenella infection was evaluated in two inbred strains of chickens (SC and TK) that...
Ding, Xicheng, Lillehoj, Hyun S., Quiroz, Marco A., Bevensee, Erich, Lillehoj, Erik P.
A purified recombinant protein from Eimeria acervulina (3-1E) was used to vaccinate chickens in ovo against coccidiosis both alone and in combination with expression plasmids encoding the interleukin...
Yun, Cheol H., Lillehoj, Hyun S., Choi, Kang D.
The role of intestinal lymphocytes and gamma interferon (IFN-γ) production in protective immunity to Eimeria tenella infection was evaluated in two inbred strains of chickens (SC and TK) that...
Ding, Xicheng, Lillehoj, Hyun S., Quiroz, Marco A., Bevensee, Erich, Lillehoj, Erik P.
A purified recombinant protein from Eimeria acervulina (3-1E) was used to vaccinate chickens in ovo against coccidiosis both alone and in combination with expression plasmids encoding the interleukin...
Humoral and cellular immune response to thyroglobulin in different inbred rat strains
Lillehoj, Hyun S., Rose, Noel R.
The role of humoral and cellular immunity in experimental autoimmune thyroiditis was examined in inbred rat strains. A significant relationship between thyroiditis and both in vitro proliferative...