Granulocytc-macrophage colony-stimulating factor stimulates arteriogenesis in a pig model of peripheral artery disease using clinically applicable infusion pumps (2006)
Grundmann, S.,
Hoefer, I.,
Ulusans, S.,
Bode, C.,
Oesterle, S.,
Tijssen, J.G.,
...
Background: A growing number of patients suffer from peripheral artery disease (PAD). Current therapies are often limited by the extent of vascular pathology and the occurrence of restenosis after...
Therapeutically induced arteriogenesis in the brain (2006)
Busch, Hans-Jörg,
Buschmann, I.,
Schneeloch, Edda,
Bode, C.,
Mies, Günter,
Hossmann, Konstantin-Alexander
Therapeutically induced arteriogenesis in the brain (2006)
Busch, Hans-Jörg,
Buschmann, I.,
Schneeloch, Edda,
Bode, C.,
Mies, Günter,
Hossmann, Konstantin-Alexander
Anti-tumor necrosis factor-alpha therapies attenuate adaptive arteriogenesis in the rabbit (2005)
Grundmann, S.,
Hoefer, I.E.,
Ulusans, S.,
Royen, N. Van,
Schirmer, S.H.,
Ozaki, C.K.,
...
START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease (2005)
Royen, N. Van,
Schirmer, S.H.,
Atasever, B.,
Behrens, C.Y.H.,
Ubbink, D.Th.,
Buschmann, E.E.,
...
START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease (2005)
Royen, N. Van,
Schirmer, S.H.,
Atasever, B.,
Behrens, C.Y.H.,
Ubbink, D.T.,
Buschmann, E.E.,
...
CD44 regulates arteriogenesis in mice and is differentially expressed in patients with poor and good collateralization (2004)
Royen, N. Van,
Voskuil, M.,
Hoefer, I.,
Jost, M.,
Graaf, S. De,
Hedwig, F.,
...
CD44 regulates arteriogenesis in mice and is differentially expressed in patients with poor and good collateralization (2004)
Royen, N. Van,
Voskuil, M.,
Hoefer, I.,
Jost, M.,
Graaf, S. De,
Hedwig, F.,
...
CD44 Regulates Arteriogenesis in Mice and Is Differentially Expressed in Patients With Poor and Good Collateralization (2004)
Van Royen, N.,
Voskuil, M.,
Hoefer, I.,
Jost, M.,
De Graaf, S.,
Hedwig, F.,
...
BACKGROUND: Arteriogenesis refers to the development of collateral conductance arteries and is orchestrated by circulating monocytes, which invade growing collateral arteries and act as suppliers of...
Effects of local MCP-1 protein therapy on the development of the collateral circulation and atherosclerosis in Watanabe hyperlipidemic rabbits (2003)
Royen, N. Van,
Hoefer, I.,
Buschmann, I.,
Kostin, S.,
Voskuil, M.,
Bode, Ch.,
...
Local monocyte chemoattractant protein-1 therapy increases collateral artery formation in apolipoprotein E-deficient mice but induces systemic monocytic CD11b expression, neointimal formation, and plaque progression (2003)
Royen, N. Van,
Hoefer, I.,
Bottinger, M.,
Hua, J.,
Grundmann, S.,
Voskuil, M.,
...
Divergent effects of GM-CSF and TGF beta(1) on bone marrow-derived macrophage arginase-1 activity, MCP-1 expression, and matrix-metalloproteinase-12: a potential role during arteriogenesis (2003)
Jost, M.M.,
Ninci, E.,
Meder, B.,
Kempf, C.,
Royen, N. Van,
Hua, J.,
...
Design of the start-trial: stimulation of arteriogenesis using subcutaneous application of gmcsf as a new treatment for peripheral vascular disease. a randomized, double-blind, placebo-controlled trial (2003)
Royen, N. Van,
Atasever, B.,
Voskuil, M.,
Katzer, E.,
Ubbink, D.Th.,
Schirmer, S.H.,
...
Influence of inflammatory cytokines on arteriogenesis (2003)
Buschmann, I.,
Heil, M.,
Jost, M.,
Schaper, W.
Blood vessel growth after birth is limited to two major processes. Angiogenesis is the growth of new capillaries by sprouting or intussusception. The major stimulus for angiogenesis is ischemia. In...
Invasive and non-invasive evaluation of spontaneous arteriogenesis in a novel porcine model for peripheral arterial obstructive disease (2003)
Buschmann, I.,
Voskuil, M.,
Van Royen, N.,
Hoefer, I.E.,
Scheffler, K.,
Grundmann, S.,
...
Local monocyte chemoattractant protein-1 therapy increases collateral artery formation in apolipoprotein E-deficient mice but induces systemic monocytic CD11b expression, neointimal formation, and plaque progression (2003)
Van Royen, N.,
Hoefer, I.,
Bottinger, M.,
Hua, J.,
Grundmann, S.,
Voskuil, M.,
...
Monocyte chemoattractant protein-1 (MCP-1) stimulates the formation of a collateral circulation on arterial occlusion. The present study served to determine whether these proarteriogenic properties...
Effects of local MCP-1 protein therapy on the development of the collateral circulation and atherosclerosis in Watanabe hyperlipidemic rabbits (2003)
Van Royen, N.,
Hoefer, I.E.,
Buschmann, I.,
Kostin, S.,
Voskuil, M.,
Bode, C.,
...
Design of the START-trial: STimulation of ARTeriogenesis using subcutaneous application of GM-CSF as a new treatment for peripheral vascular disease. A randomized, double-blind, placebo-controlled trial (2003)
Van Royen, N.,
Piek, J. J.,
Legemate, D. A.,
Schaper, W.,
Oskam, J.,
Atasever, B.,
...
Peripheral arterial disease (PAD) affects a large percentage of the elderly population. Standard invasive treatment, apart from risk factor modulation, consists of bypass surgery or percutaneous...
Modulation of collateral artery growth in a porcine hindlimb ligation model using MCP-1 (2003)
Voskuil, M.,
Van Royen, N.,
Hoefer, I.E.,
Seidler, R.,
Guth, B.D.,
Bode, C.,
...
Effects of local MCP-1 protein therapy on the development of the collateral circulation and atherosclerosis in Watanabe hyperlipidemic rabbits (2003)
Van Royen, N,
Hoefer, I,
Buschmann, I,
Kostin, S,
Voskuil, M,
Bode, Ch,
...
Objective: The objective of our study was to quantify the arteriogenic potency of Monocyte Chemoattractant Protein-1 (MCP-1) under hyperlipidemic conditions. Additionally, we aimed to determine the...
Exogenous application of transforming growth factor beta 1 stimulates arteriogenesis in the peripheral circulation (2002)
Royen, N. Van,
Hoefer, I.,
Buschmann, I.,
Heil, M.,
Kostin, S.,
Deindl, E.,
...
Exogenous application of tranforming growth factor beta 1 stimulates arteriogenesis in the peripheral circulation (2002)
Van Royen, N.,
Hoefer, I.,
Buschmann, I.,
Heil, M.,
Kostin, S.,
Deindl, E.,
...
Angiogenese en arteriogenese; de lange weg van concept naar klinische toepassing (2001)
Voskuil, M.,
Royen, N. Van,
Hoefer, I.,
Buschmann, I.,
Schaper, W.,
Piek, J.J.
Stimulation of arteriogenesis; a new concept for the treatment of arterial occlusive disease (2001)
Royen, N. Van,
Piek, J.J.,
Buschmann, I.,
Hoefer, I.E.,
Voskuil, M.,
Schaper, W.