COBDEN, I., MATTHEWSON, K., CARR, W. P., DICK, W. C., RECORD, C. O.
The effects of acute ethanol challenge on serum glycoprotein concentrations in man were studied. Serum levels of haptoglobin, α-2-macroglobulin and pre-albumin were measured fasting and 6 hr after...
COBDEN, I., BASSENDINE, M. F., JAMES, O. F. W.
Over a four-year period 40 patients of local origin, with primary hepatocellular carcinoma were seen at a regional referral centre. Twenty-nine patients had histological evidence of underlying...
British Library microfilm no. : D50496/84.
Prospective comparison of three non-invasive tests for pancreatic disease.
Cobden, I, Lendrum, R, James, O F, Venables, C W, Tarbit, I, Hawkins, T
Prospective comparison of three non-invasive tests for pancreatic disease.
Cobden, I, Lendrum, R, James, O F, Venables, C W, Tarbit, I, Hawkins, T
Hepatotoxicity of herbal remedies.
MacGregor, F. B., Abernethy, V. E., Dahabra, S., Cobden, I., Hayes, P. C.
Should colonoscopy be the first investigation for colonic disease?
Lindsay, D C, Freeman, J G, Cobden, I, Record, C O
Many patients with suspected colonic disease undergo rigid sigmoidoscopy, barium enema examination, and ultimately total colonoscopy, but the need for preliminary radiology has not been formally...
Zaitoun, A M, Cobden, I, Al Mardini, H, Record, C O
Morphometric measurements were performed on rectal biopsy specimens from 10 normal control subjects and 33 patients with a relapse of distal ulcerative colitis before and after treatment for four...
Proximal stomach and antrum in stomach emptying.
Barker, M C, Cobden, I, Axon, A T
In a series of measurements of liquid-phase gastric emptying using a radionuclide marker on 35 subjects, five were identified in whom the proximal stomach and antrum were clearly distinguishable....
Intestinal permeability in rats infected by Nippostrongylus brasiliensis.
Cobden, I, Rothwell, J, Axon, A T
Passive intestinal permeability has been investigated in rats infected by the nematode, Nippostrongylus brasiliensis, by the simultaneous administration of two probe molecules. Experiments using a...
Small intestinal structure and passive permeability in systemic sclerosis.
Cobden, I, Rothwell, J, Axon, A T, Dixon, M F, Lintott, D J, Rowell, N R
Seventeen patients with proven systemic sclerosis had a peroral jejunal biopsy performed. Four biopsies were regarded as showing abnormalities, which were mostly confined to the deeper structures,...
Hamilton, I, Cobden, I, Rothwell, J, Axon, A T
Intestinal permeability has been studied in 21 patients with coeliac disease in relapse and after gluten withdrawal using an oral test of intestinal permeability based on the simultaneous oral...
Intestinal permeability and screening tests for coeliac disease.
Cobden, I, Rothwell, J, Axon, A T
In disease states of the small intestine--for example, gluten-sensitive enteropathy--there is an increased permeability to large molecules. This increased permeability extends to polar molecules of...
Hamilton, I, Worsley, B W, Cobden, I, Cooke, E M, Shoesmith, J G, Axon, A T
Both saliva and jejunal aspirate were cultured from 22 patients with suspected small bowel bacterial overgrowth and from eight controls. Large numbers of organisms (greater than 10(6)/ml) were...
McKay, J, Rawlings, M D, Cobden, I, James, O F
1 The effects of single doses (25 g and 50 g) oral ethanol on the disposition of acetanilide (50 mg/kg metabolic active mass) has been studied in normal subjects, and in patients with chronic...
Bronchiolitis obliterans organising pneumonia in a patient with ulcerative colitis.
Swinburn, C R, Jackson, G J, Cobden, I, Ashcroft, T, Morritt, G N, Corris, P A
A young woman with ulcerative colitis developed pneumonia, which responded to corticosteroids. Histological examination showed this to be bronchiolitis obliterans organising pneumonia.
Fatal intrahepatic cholestasis associated with triazolam
Cobden, I., Record, C. O., White, R. W. B.
A 44-year-old man developed severe pruritus with jaundice which subsequently proved fatal. Liver histology showed intense cholestasis, but at post-morten the bile ducts were patent and there was no...
Hepatic epithelioid haemangioendothelioma: difficult name, difficult diagnosis?
Cobden, I., Johri, S., Terry, G., Robinson, K. B., Bennett, M. K., Lendrum, R.
Two patients with epithelioid haemangioendotheliomata of the liver are described. Both presented with abdominal pain and malaise, with hepatomegaly and a variable degree of hepatocellular...
Hepatic abnormalities in coeliac disease: three cases of delayed diagnosis.
Mitchison, H. C., Record, C. O., Bateson, M. C., Cobden, I.
Three cases of biopsy-proven coeliac disease are presented. In each case the predominant clinical and laboratory features suggested liver disease, bowel symptoms were a minor part of the presentation...
Should colonoscopy be the first investigation for colonic disease?
Lindsay, D C, Freeman, J G, Cobden, I, Record, C O
Many patients with suspected colonic disease undergo rigid sigmoidoscopy, barium enema examination, and ultimately total colonoscopy, but the need for preliminary radiology has not been formally...