I. Herr

Publication List Details

Period

1992 - 2006

Number

37

Co-Authors

Mechanismen der Transkriptionskontrolle des Proto-Onkogens c-jun. (1995)

Herr, I.

Wissenschaftliche Berichte, FZKA-5566B (Februar 95)

Regulation of AP-1 and AP-1-dependent genes by stress stimuli. (1995)

Wilhelm, D., Van Dam, H., Baumann, B., Herr, I., Angel, P.

Workshop on Regulation of Expression of Cell Stress Genes, Ravello, I, April 1-3, 1995

Binding of promoter-associated AP-1 is not altered during induction and subsequent repression of the c-jun promoter by TPA and UV irradiation. (1994)

Herr, I., Van Dam, H., Angel, P.

Cold Spring Harbor Laboratory Meeting 'Cancer Cells: Regulation of Eucaryotic Gene Transcription', Cold Spring Harbor, N.Y., September 1-5, 1993

Multiple mechanisms to regulate the activity of the transcription factor Jun. (1993)

Schorpp, M., Oehler, T., Herr, I., Hagmeyer, B., Angel, P.

8th Internat.Symp.on Prevention and Detection of Cancer: Cofactor Interactions and Cancer Prevention, Nice, F, March 17-19, 1993

The DNA binding domain of c-jun is a target for repression of AP1 activity by E1A. (1992)

Angel, P., Hagmeyer, B., Oehler, T., Herr, I., Koenig, H., ...

Keystone Symp.on Molecular and Cellular Biology, Copper Mountain, Colo., March 28 - April 4, 1992

AP1: multiple mechanisms to regulate its activity. (1992)

Angel, P., Oehler, T., Hagmeyer, B., Gebel, S., Koenig, H., Herr, I., ...

2nd Internat.Symp.on Molecular Hematology, Freiburg, June 18-20, 1992

Cell-type specific DNA-protein interactions at the tissue-type plasminogen activator promoter in human endothelial and HeLa cells in vivo and in vitro.

Arts, J, Herr, I, Lansink, M, Angel, P, Kooistra, T

Tissue-type plasminogen activator (t-PA) gene expression in human endothelial cells and HeLa cells is stimulated by the protein kinase C activator phorbol 12-myristate 13-acetate (PMA) at the level...

A switch region determines the cell type-specific positive or negative action of YY1 on the activity of the human papillomavirus type 18 promoter.

Bauknecht, T, Jundt, F, Herr, I, Oehler, T, Delius, H, Shi, Y, ...

YY1 is a zinc finger transcription factor which acts as either a repressor or an activator dependent on the promoter context. YY1 is a potent activator of the genuine human papillomavirus type 18...

Resistance of chimpanzee T cells to human immunodeficiency virus type 1 Tat-enhanced oxidative stress and apoptosis.

Ehret, A, Westendorp, M O, Herr, I, Debatin, K M, Heeney, J L, Frank, R, ...

CD4+ T-cell depletion in AIDS patients involves induction of apoptosis in human immunodeficiency virus (HIV)-infected and noninfected T cells. The HIV type 1 (HIV-1)-transactivating protein Tat...

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.

Van Dam, H, Wilhelm, D, Herr, I, Steffen, A, Herrlich, P, Angel, P

The major regulators of the c-jun promoter are ATF-2 and c-Jun. They act as pre-bound heterodimers on two 'AP-1-like' sites, and are preferentially addressed by different types of extracellular...

Adenovirus E1A negatively and positively modulates transcription of AP-1 dependent genes by dimer-specific regulation of the DNA binding and transactivation activities of Jun.

Hagmeyer, B M, König, H, Herr, I, Offringa, R, Zantema, A, ...

Adenovirus E1A proteins inhibit expression of the collagenase gene but activate expression of the c-jun gene. Both effects are mediated by TPA-responsive elements (TREs), the binding sites for...

Structural organization and chromosomal localization of the mouse collagenase type I gene.

Schorpp, M, Mattei, M G, Herr, I, Gack, S, Schaper, J, Angel, P

A clone containing genomic sequences of part of the murine collagenase type 1 (MMP-1) gene was isolated. It contains exons 1-6 encoding all the domains required for collagenase function and 9 kb of...

Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis.

Herr, I, Wilhelm, D, Böhler, T, Angel, P, Debatin, K M

We report here that anticancer drugs such as doxorubicin lead to induction of the CD95 (APO-1/Fas) system of apoptosis and the cellular stress pathway which includes JNK/SAPKs. Ceramide, which...

Cell-type specific DNA-protein interactions at the tissue-type plasminogen activator promoter in human endothelial and HeLa cells in vivo and in vitro.

Arts, J, Herr, I, Lansink, M, Angel, P, Kooistra, T

Tissue-type plasminogen activator (t-PA) gene expression in human endothelial cells and HeLa cells is stimulated by the protein kinase C activator phorbol 12-myristate 13-acetate (PMA) at the level...

A switch region determines the cell type-specific positive or negative action of YY1 on the activity of the human papillomavirus type 18 promoter.

Bauknecht, T, Jundt, F, Herr, I, Oehler, T, Delius, H, Shi, Y, ...

YY1 is a zinc finger transcription factor which acts as either a repressor or an activator dependent on the promoter context. YY1 is a potent activator of the genuine human papillomavirus type 18...

Resistance of chimpanzee T cells to human immunodeficiency virus type 1 Tat-enhanced oxidative stress and apoptosis.

Ehret, A, Westendorp, M O, Herr, I, Debatin, K M, Heeney, J L, Frank, R, ...

CD4+ T-cell depletion in AIDS patients involves induction of apoptosis in human immunodeficiency virus (HIV)-infected and noninfected T cells. The HIV type 1 (HIV-1)-transactivating protein Tat...

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents.

Van Dam, H, Wilhelm, D, Herr, I, Steffen, A, Herrlich, P, Angel, P

The major regulators of the c-jun promoter are ATF-2 and c-Jun. They act as pre-bound heterodimers on two 'AP-1-like' sites, and are preferentially addressed by different types of extracellular...

Adenovirus E1A negatively and positively modulates transcription of AP-1 dependent genes by dimer-specific regulation of the DNA binding and transactivation activities of Jun.

Hagmeyer, B M, König, H, Herr, I, Offringa, R, Zantema, A, ...

Adenovirus E1A proteins inhibit expression of the collagenase gene but activate expression of the c-jun gene. Both effects are mediated by TPA-responsive elements (TREs), the binding sites for...

Structural organization and chromosomal localization of the mouse collagenase type I gene.

Schorpp, M, Mattei, M G, Herr, I, Gack, S, Schaper, J, Angel, P

A clone containing genomic sequences of part of the murine collagenase type 1 (MMP-1) gene was isolated. It contains exons 1-6 encoding all the domains required for collagenase function and 9 kb of...

Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis.

Herr, I, Wilhelm, D, Böhler, T, Angel, P, Debatin, K M

We report here that anticancer drugs such as doxorubicin lead to induction of the CD95 (APO-1/Fas) system of apoptosis and the cellular stress pathway which includes JNK/SAPKs. Ceramide, which...

VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma

Beckermann, B M, Kallifatidis, G, Groth, A, Frommhold, D, Apel, A, Mattern, J, ...

Little is known about the factors that enable the mobilisation of human mesenchymal stem cells (MSC) from the bone marrow into the blood stream and their recruitment to and retention in the tumour....

Dexamethasone-induced cisplatin and gemcitabine resistance in lung carcinoma samples treated ex vivo

Gassler, N, Zhang, C, Wenger, T, Schnabel, P A, Dienemann, H, Debatin, K-M, ...

Chemotherapy for lung cancer not only has severe side effects but frequently also exhibits limited, if any clinical effectiveness. Dexamethasone (DEX) and similar glucocorticoids (GCs) such as...