Beed, M., O'Connor, M. B., Kaur, J., Mahajan, R. P., Moppett, I. K.
Background Forearm skin vascular reactivity may be assessed using a transient hyperaemic response (THR) after 20 s of brachial artery compression. THR has been manipulated by iontophoresis of...
Wiles, M. D., Dickson, E., Moppett, I. K.
Background Local anaesthetics affect blood vessels in various ways, depending upon the site of action and the drug used. There is controversy over the vascular effects of two widely used topical...
Maxwell, M. J., Moran, C. G., Moppett, I. K.
Background Hip fractures are common in the elderly and have a high 30 day postoperative mortality. The ability to recognize patients at high risk of poor outcomes before operation would be an...
Moppett, I. K., Sherman, R. W., Wild, M. J., Latter, J. A., Mahajan, R. P.
Background The effects of vasoactive substances on cerebral haemodynamics are not fully known. We studied the effects of norepinephrine and glyceryl trinitrate (GTN) on cerebral haemodynamics in...
POSSUM scoring for patients with fractured neck of femur (2005)
Ramanathan, T. S., Moppett, I. K., Wenn, R., Moran, C. G.
Background. POSSUM scoring is validated as an audit tool in general and orthopaedic surgery. It is also used for preoperative triage to assess perioperative risk. However its ability to predict...
The dependence of measured alveolar deadspace on anatomical deadspace volume (2005)
Moppett, I. K., Gornall, C. B., Hardman, J. G.
Background. Changes in pulmonary deadspace are indicators of disease status (e.g. pulmonary embolus, acute respiratory distress syndrome) and they have prognostic usefulness in the intensive care...
POSSUM scoring for patients with fractured neck of femur{dagger} (2005)
Ramanathan, T. S., Moppett, I. K., Wenn, R., Moran, C. G.
Background. POSSUM scoring is validated as an audit tool in general and orthopaedic surgery. It is also used for preoperative triage to assess perioperative risk. However its ability to predict...
The dependence of measured alveolar deadspace on anatomical deadspace volume (2005)
Moppett, I. K., Gornall, C. B., Hardman, J. G.
Background. Changes in pulmonary deadspace are indicators of disease status (e.g. pulmonary embolus, acute respiratory distress syndrome) and they have prognostic usefulness in the intensive care...
Moppett, I. K., Wild, M. J., Sherman, R. W., Latter, J. A., Miller, K., Mahajan, R. P.
Background. Sympathomimetic drugs are assumed to have no direct effects on cerebral haemodynamics on the basis of animal experiments; there is little evidence of their direct effects in humans. This...
Brown, H., Moppett, I. K., Mahajan, R. P.
Background. Recently, the transient hyperaemic response (THR) to brief compression (20 s) of the brachial artery has been described as a way to assess vascular reactivity of the forearm skin. We...
Moppett, I. K., Davies, J. A., Mahajan, R. P.
Background. Cyclo‐oxygenase‐2 (COX‐2)‐specific inhibitors are marketed as safer analgesics than non‐selective non‐steroidal anti‐inflammatory drugs. However, there...