I. M. Appel

Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia (2005)

Stams, W.A., Boer, M.L. Den, Holleman, A., Appel, I.M., Beverloo, H.B., Wering, E.R. Van, ...

Resistance to L-asparaginase in leukemic cells may be caused by an elevated cellular expression of asparagine synthetase (AS). Previously, we reported that high AS expression did not correlate to...

SIOP treatment guidelines for renal tumours in small infants: fact or fantasy? (2000)

Levie, N.S., Kraker, J. De, Bokkerink, J.P.M., Appel, I.M., Aronson, D.C.