Epstein, H.S., Tomic, M., Freedberg, I.M., Blumenberg, M.
To elucidate the elements required for regulation of keratin expression in epidermis, we have linked a short, 300 base pair segment, corresponding to the promoter region of a human K # 14 gene, to...
Jiang, C K, Magnaldo, T, Ohtsuki, M, Freedberg, I M, Bernerd, F, Blumenberg, M
Epidermal injury results in activation of keratinocytes which produce and respond to growth factors and cytokines and become migratory. Activated keratinocytes express a specific pair of keratin...
Epithelial-specific keratin gene expression: identification of a 300 base-pair controlling segment.
Jiang, C K, Epstein, H S, Tomic, M, Freedberg, I M, Blumenberg, M
To elucidate the elements required for regulation of keratin expression in epidermis, we have linked a short, 300 base pair segment, corresponding to the promoter region of a human K#14 gene, to the...
Jiang, C K, Flanagan, S, Ohtsuki, M, Shuai, K, Freedberg, I M, Blumenberg, M
Epidermal keratinocytes have important immunologic functions, which is apparent during wound healing, in psoriasis, and in allergic and inflammatory reactions. In these processes, keratinocytes not...
Nuclear receptors for retinoic acid and thyroid hormone regulate transcription of keratin genes.
Tomic, M, Jiang, C K, Epstein, H S, Freedberg, I M, Samuels, H H, Blumenberg, M
In the epidermis, retinoids regulate the expression of keratins, the intermediate filament proteins of epithelial cells. We have cloned the 5' regulatory regions of four human epidermal keratin...
Jiang, C K, Magnaldo, T, Ohtsuki, M, Freedberg, I M, Bernerd, F, Blumenberg, M
Epidermal injury results in activation of keratinocytes which produce and respond to growth factors and cytokines and become migratory. Activated keratinocytes express a specific pair of keratin...
Epithelial-specific keratin gene expression: identification of a 300 base-pair controlling segment.
Jiang, C K, Epstein, H S, Tomic, M, Freedberg, I M, Blumenberg, M
To elucidate the elements required for regulation of keratin expression in epidermis, we have linked a short, 300 base pair segment, corresponding to the promoter region of a human K#14 gene, to the...
Jiang, C K, Flanagan, S, Ohtsuki, M, Shuai, K, Freedberg, I M, Blumenberg, M
Epidermal keratinocytes have important immunologic functions, which is apparent during wound healing, in psoriasis, and in allergic and inflammatory reactions. In these processes, keratinocytes not...
Nuclear receptors for retinoic acid and thyroid hormone regulate transcription of keratin genes.
Tomic, M, Jiang, C K, Epstein, H S, Freedberg, I M, Samuels, H H, Blumenberg, M
In the epidermis, retinoids regulate the expression of keratins, the intermediate filament proteins of epithelial cells. We have cloned the 5' regulatory regions of four human epidermal keratin...
Embryonic expression of the human 40-kD keratin: evidence from a processed pseudogene sequence.
Savtchenko, E S, Schiff, T A, Jiang, C K, Freedberg, I M, Blumenberg, M
Analysis of the cytoskeletal components of early murine embryos has detected expression of two keratin proteins, K#8 and K#18, at the 4-8-cell stage. Comparable data for human embryos do not exist,...