I. T. Magrath

Publication List Details

Period

1974 - 1997

Number

24

Co-Authors

The treatment of pediatric lymphomas: Paradigms to plagiarize? (1997)

Magrath, I. T.

The excellent results in pediatric lymphomas pnsented at the Sixth International Conference on Malignant Lymphoma in Lugano encompass several emerging themes and provide paradigms which it may be...

Prospects for the therapeutic use of antisense oligonucleotides in malignant lymphomas (1994)

Magrath, I. T.

Combinations of cytotoxic drugs, based almost entirely upon the results of empirical clinical trials, are the foundation of the modern management of the non-Hodgkin's lymphomas. While highly...

Intracerebral Burkitt's Lymphoma: Pathology, Clinical Features and Treatment (1974)

MAGRATH, I. T., MUGERWA, J., BAILEY, I., OLWENY, C., KIRYABWIRE, Y.

Intracerebral Burkitt's lymphoma has previously been reported as a postmortem finding. Six patients are described here in whom intracerebral Burkitt's lymphoma was diagnosed prior to death. In all...

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.

Gaidano, G, Ballerini, P, Gong, J Z, Inghirami, G, Neri, A, Newcomb, E W, ...

We have investigated the frequency of p53 mutations in B- and T-cell human lymphoid malignancies, including acute lymphoblastic leukemia, the major subtypes of non-Hodgkin lymphoma, and chronic...

Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma.

Neri, A, Barriga, F, Knowles, D M, Magrath, I T, Dalla-Favera, R

We show that endemic (eBL), sporadic (sBL), and acquired immunodeficiency syndrome-associated (AIDS-BL) forms of Burkitt lymphoma (BL) carrying t(8;14) chromosomal translocations display different...

Induction of plasmacytoid differentiation by phorbol ester in B-cell lymphoma cell lines bearing 8;14 translocations.

Benjamin, D, Magrath, I T, Triche, T J, Schroff, R W, Jensen, J P, Korsmeyer, S J

At nanomolar concentrations, phorbol 12-myristate 13-acetate induced differentiation in a human Epstein-Barr virus-negative B-cell line, JD 38, derived from an undifferentiated lymphoma and...

Burkitt lymphoma cell line carrying a variant translocation creates new DNA at the breakpoint and violates the hierarchy of immunoglobulin gene rearrangement.

Denny, C T, Hollis, G F, Magrath, I T, Kirsch, I R

The Burkitt lymphoma cell line KK124, which contains a reciprocal t(8;22) translocation, was shown to have rearranged in a region 3' to the c-myc proto-oncogene on chromosome 8 and 5' to the lambda...

Burkitt's Tumors Contain Particles Encapsulating RNA-Instructed DNA Polymerase and High Molecular Weight Virus-Related RNA

Kufe, D., Magrath, I. T., Ziegler, J. L., Spiegelman, S.

Burkitt's lymphomas, linked by previous studies with the DNA-containing Epstein-Barr virus, contain an RNA related in sequence to that of Rauscher leukemia virus. The present study establishes that...

The role of surgery in the management of American Burkitt's lymphoma and its treatment.

Kemeny, M M, Magrath, I T, Brennan, M F

Ninety-two patients with American Burkitt's lymphoma were studied retrospectively to elucidate the role of surgery in the complications of treatment of Burkitt's lymphoma. All of the patients...

Surgical Reduction of Tumour Bulk in Management of Abdominal Burkitt's Lymphoma

Magrath, I. T., Lwanga, S., Carswell, W., Harrison, N.

The results of a retrospective study of the value of reductive surgery in the treatment of abdominal Burkitt's lymphoma are reported. Nine patients had almost complete removal of the tumour, 16 had...

Failure of BCG immunostimulation to affect the clinical course of Burkitt's lymphoma.

Magrath, I T, Ziegler, J L

A controlled randomised trial was carried out to evaluate the efficacy of BCG immunotherapy in preventing relapse in patients with Burkitt's lymphoma in whom remission had been induced with...

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.

Gaidano, G, Ballerini, P, Gong, J Z, Inghirami, G, Neri, A, Newcomb, E W, ...

We have investigated the frequency of p53 mutations in B- and T-cell human lymphoid malignancies, including acute lymphoblastic leukemia, the major subtypes of non-Hodgkin lymphoma, and chronic...

Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma.

Neri, A, Barriga, F, Knowles, D M, Magrath, I T, Dalla-Favera, R

We show that endemic (eBL), sporadic (sBL), and acquired immunodeficiency syndrome-associated (AIDS-BL) forms of Burkitt lymphoma (BL) carrying t(8;14) chromosomal translocations display different...

Induction of plasmacytoid differentiation by phorbol ester in B-cell lymphoma cell lines bearing 8;14 translocations.

Benjamin, D, Magrath, I T, Triche, T J, Schroff, R W, Jensen, J P, Korsmeyer, S J

At nanomolar concentrations, phorbol 12-myristate 13-acetate induced differentiation in a human Epstein-Barr virus-negative B-cell line, JD 38, derived from an undifferentiated lymphoma and...

Burkitt lymphoma cell line carrying a variant translocation creates new DNA at the breakpoint and violates the hierarchy of immunoglobulin gene rearrangement.

Denny, C T, Hollis, G F, Magrath, I T, Kirsch, I R

The Burkitt lymphoma cell line KK124, which contains a reciprocal t(8;22) translocation, was shown to have rearranged in a region 3' to the c-myc proto-oncogene on chromosome 8 and 5' to the lambda...

Burkitt's Tumors Contain Particles Encapsulating RNA-Instructed DNA Polymerase and High Molecular Weight Virus-Related RNA

Kufe, D., Magrath, I. T., Ziegler, J. L., Spiegelman, S.

Burkitt's lymphomas, linked by previous studies with the DNA-containing Epstein-Barr virus, contain an RNA related in sequence to that of Rauscher leukemia virus. The present study establishes that...

The role of surgery in the management of American Burkitt's lymphoma and its treatment.

Kemeny, M M, Magrath, I T, Brennan, M F

Ninety-two patients with American Burkitt's lymphoma were studied retrospectively to elucidate the role of surgery in the complications of treatment of Burkitt's lymphoma. All of the patients...

Surgical Reduction of Tumour Bulk in Management of Abdominal Burkitt's Lymphoma

Magrath, I. T., Lwanga, S., Carswell, W., Harrison, N.

The results of a retrospective study of the value of reductive surgery in the treatment of abdominal Burkitt's lymphoma are reported. Nine patients had almost complete removal of the tumour, 16 had...

Failure of BCG immunostimulation to affect the clinical course of Burkitt's lymphoma.

Magrath, I T, Ziegler, J L

A controlled randomised trial was carried out to evaluate the efficacy of BCG immunotherapy in preventing relapse in patients with Burkitt's lymphoma in whom remission had been induced with...

Medical Presentations of Choriocarcinoma

Magrath, I. T., Golding, P. R., Bagshawe, K. D.

Choriocarcinoma commonly presents with symptoms resulting from metastases in the lungs, central nervous system, or alimentary tract. This tumour may occur without any gynaecological symptoms and when...

Survival of candida septicaemia treated with amphotericin B

Mitchell, A. B. S., Hosking, G., Magrath, I. T., Farthing, C. P.

Candida albicans septicaemia occurred in an alcoholic woman who had severe hepatic dysfunction, and was further debilitated by multiple cardiac arrests, prolonged artificial ventilation,...

Fine Needle Aspiration in the Diagnosis of Childhood Malignant Disease in Uganda

Magrath, I. T.

One hundred aspirations using a fine needle have been performed on 94 patients with a suspected diagnosis of malignant tumour, 31 of which were in patients with recurrent tumour. In 90 aspirates...