The RESCUEicp decompressive craniectomy trial (2009)
Hutchinson, P, Timofeev, I, Grainger, S, Corteen, E
No abstract available.
Brain tissue oxygenation: more than a number (2008)
Radolovich, DK, Timofeev, I, Lavinio, A, Czosnyka, M, Kim, DJ, Hutchinson, P, ...
No abstract available.
Cerebrovascular reactivity during hypothermia and rewarming (2007)
Lavinio, A., Timofeev, I., Nortje, J., Outtrim, J., Smielewski, P., Gupta, A., ...
Background Experimental evidence from a murine model of traumatic brain injury (TBI) suggests that hypothermia followed by fast rewarming may damage cerebral microcirculation. The effects of...
Zygun, D, Nortje, J, Hutchinson, P, Timofeev, I, Menon, D, Gupta, A
No abstract available.
Abstract. We develop a new computationally efficient approach for the analysis of complex large-scale neurobiological networks. Its key element is the use of a new phenomenological model of a neuron...
Selective Amplification of Neocortical Neuronal Output by Fast Prepotentials In Vivo (2004)
Crochet, S., Fuentealba, P., Timofeev, I., Steriade, M.
Neocortical cells integrate inputs from thousands of presynaptic neurons distributed along their dendritic arbors. Propagation of post-synaptic potentials to the soma is crucial in determining...
Selective Amplification of Neocortical Neuronal Output by Fast Prepotentials InVivo (2004)
Crochet, S., Fuentealba, P., Timofeev, I., Steriade, M.
Neocortical cells integrate inputs from thousands of presynaptic neurons distributed along their dendritic arbors. Propagation of postsynaptic potentials to the soma is crucial in determining...
Selective Amplification of Neocortical Neuronal Output by Fast Prepotentials In Vivo (2004)
Crochet, S., Fuentealba, P., Timofeev, I., Steriade, M.
Neocortical cells integrate inputs from thousands of presynaptic neurons distributed along their dendritic arbors. Propagation of post-synaptic potentials to the soma is crucial in determining...
Origin of Slow Cortical Oscillations in Deafferented Cortical Slabs (2000)
Timofeev, I., Grenier, F., Bazhenov, M., Sejnowski, T.J., Steriade, M.
An in vivo preparation has been developed to study the mechanisms underlying spontaneous sleep oscillations. Dual and triple simultaneous intracellular recordings were made from neurons in small...
Stationary Electric Arc Plasma Generator for Influencing on Supersonic Gas Flow (1998)
Ardelyan, N., Bychkov, V., Kosmachevskii, K., Timofeev, I.
Studies of plasma jet interaction with cross flows has been made for development of the concept of enhancing of combustion and ignition at application of plasma jets. A computer simulation of a cross...
Leading role of thalamic over cortical neurons during postinhibitory rebound excitation
Grenier, F., Timofeev, I., Steriade, M.
The postinhibitory rebound excitation is an intrinsic property of thalamic and cortical neurons that is implicated in a variety of normal and abnormal operations of neuronal networks, such as slow or...
1. Intracellular recordings from 216 thalamocortical (TC) neurones in the ventrolateral (VL) nucleus of intact-cortex and decorticated cats under ketamine-xylazine anaesthesia revealed spontaneously...
Contreras, D, Timofeev, I, Steriade, M
1. To explore the nature of the long-lasting hyperpolarizations that characterize slow oscillations in corticothalamic circuits in vivo, intracellular recordings were obtained under ketamine-xylazine...
Timofeev, I, Contreras, D, Steriade, M
1. The fluctuations during various phases of the slow sleep oscillation (< 1 Hz) in synaptic responsiveness of motor cortical (Cx), thalamic reticular (RE) and thalamocortical (TC) neurones were...
Leading role of thalamic over cortical neurons during postinhibitory rebound excitation
Grenier, F., Timofeev, I., Steriade, M.
The postinhibitory rebound excitation is an intrinsic property of thalamic and cortical neurons that is implicated in a variety of normal and abnormal operations of neuronal networks, such as slow or...
1. Intracellular recordings from 216 thalamocortical (TC) neurones in the ventrolateral (VL) nucleus of intact-cortex and decorticated cats under ketamine-xylazine anaesthesia revealed spontaneously...
Contreras, D, Timofeev, I, Steriade, M
1. To explore the nature of the long-lasting hyperpolarizations that characterize slow oscillations in corticothalamic circuits in vivo, intracellular recordings were obtained under ketamine-xylazine...
Timofeev, I, Contreras, D, Steriade, M
1. The fluctuations during various phases of the slow sleep oscillation (< 1 Hz) in synaptic responsiveness of motor cortical (Cx), thalamic reticular (RE) and thalamocortical (TC) neurones were...
Effect of Synaptic Connectivity on Long-Range Synchronization of Fast Cortical Oscillations
Bazhenov, M., Rulkov, N. F., Timofeev, I.
Cortical gamma oscillations in the 20- to 80-Hz range are associated with attentiveness and sensory perception and have strong connections to both cognitive processing and temporal binding of sensory...