Ian A. Shiels

In vitro effect of canine hyperimmune sera on TNFa activity (2006)

Kotiw, Michael, Shiels, Ian A., Wilson, Ross P., Reeve-Johnson, LLoyd

[Introduction]: Septic shock in dogs is caused by cardiovascular and vasomotor failure associated with an uncontrolled intrinsic release of inflammatory mediators [1–5]. The syndrome is...

In vitro effect of canine hyperimmune sera on TNFa activity (2006)

Kotiw, Michael, Shiels, Ian A., Wilson, Ross P., Reeve-Johnson, LLoyd

[Introduction]: Septic shock in dogs is caused by cardiovascular and vasomotor failure associated with an uncontrolled intrinsic release of inflammatory mediators [1–5]. The syndrome is...

Modelling the inflammation of asthma and uveitis to investigate the role of medications in its moderation and exacerbation in these diseases /--Ian A. Shiels. (1997)

Shiels, Ian A.

Thesis (Ph. D.)--University of Queensland, 1998.

Modelling the inflammation of asthma and uveitis to investigate the role of medications in its moderation and exacerbation in these diseases (1997)

Shiels, Ian A.

Includes bibliography.

Effects of a new C5a receptor antagonist on C5a- and endotoxin- induced neutropenia in the rat

Short, Anna, Wong, Allan K, Finch, Angela M, Haaima, Gerald, Shiels, Ian A, Fairlie, David P, ...

A new C5a receptor antagonist, the cyclic peptide Phe-[Orn-Pro-D-cyclohexylalanine-Trp-Arg], (F-[OPdChaWR]), was tested for its ability to antagonize the neutropenic effects of both C5a and endotoxin...

Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist

Strachan, Anna J, Shiels, Ian A, Reid, Robert C, Fairlie, David P, Taylor, Stephen M

Initiation of a peritoneal Arthus reaction by deposition of immune-complexes results in vascular leakage, polymorphonuclear leukocyte (PMN) infiltration, and tumour necrosis factor α (TNFα) and...

Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist

Strachan, Anna J, Shiels, Ian A, Reid, Robert C, Fairlie, David P, Taylor, Stephen M

Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist

Arumugam, Thiruma V, Arnold, Naomi, Proctor, Lavinia M, Newman, Michelle, Reid, Robert C, Hansford, Karl A, ...

A new group IIa sPLA2 inhibitor was compared with selective inhibitors of COX-1, COX-2 and an LTC4 antagonist for effects on local and remote tissue injuries following ischaemia and reperfusion (I/R)...