Late widespread skeletal metastases from myxoid liposarcoma detected by MRI only (2008)
Hanna, Sammy A, Qureshi, Yassar A, Bayliss, Lee, David, Lee A, O'Donnell, Paul, Judson, Ian R, ...
Abstract Background Myxoid liposarcoma is the second most commonly occurring sub-type of liposarcomas. In contrast to other soft tissue sarcomas, it is known to have a tendency to spread toward...
Garrett, Christopher R, Blackstein, Martin E, Shah, Manisha H, Verweij, Jaap, ...
BACKGROUND: No effective therapeutic options for patients with unresectable imatinib-resistant gastrointestinal stromal tumour are available. We did a randomised, double-blind, placebo-controlled,...
Verweij, Jaap, Casali, Paolo G, Simes, John, Le Cesne, Axel, Reichardt, Peter, ...
The aim of this study was to identify prognostic factors for toxicity to treatment with imatinib. The study was based on 942 patients with gastrointestinal stromal tumours (GIST) randomised to...
Verweij, Jaap, Casali, Paolo G, Le Cesne, Axel, Hohenberger, Peter, Ray-Coquard, Isabelle, ...
PURPOSE: The aim of this study was to identify factors predicting initial and late resistance of GI stromal tumor (GIST) patients to imatinib and to document the dose-response relationship in the...
Emma L. Spurrell, Yen C. Yeo, Terence P. Rollason, Ian R. Judson
Purpose:To discuss a case of ovarian fibromatosis/massive ovarian oedema, intra-abdominal fibromatosis, sclerosing peritonitis and Meig's syndrome. To review the reported therapeutic...
Chung, Yuen-Li, Troy, Helen, Banerji, Udai, Jackson, Laura E., Walton, Mike I., Stubbs, Marion, ...
Background: 17-Allylamino,17-demethoxygeldanamycin (17AAG) is a novel anticancer drug that inhibits heat shock protein 90 (Hsp90), resulting in proteasomal degradation of several oncogenic proteins....
Judson, Ian R, Verweij, Jaap, Stroobants, Sigrid, Donato Di Paola, Eugenio, ...
In a phase I study conducted by the EORTC Soft Tissue and Bone Sarcoma Group, 40 patients with advanced soft tissue sarcomas, most of whom had gastrointestinal stromal tumors (GISTs), received...
Mark W. Verrill, Helen M. Coley, Ian R. Judson, Cyril Fisher
Purpose. Deep fibromatoses are large, often rapidly growing but benign soft tissue tumours. Although surgery is the mainstay of treatment, in unremitting and aggressive cases the use of cytotoxic...
A Phase I/II Study of a 72-h Continuous Infusion of Etoposide in Advanced Soft Tissue Sarcoma (1997)
Charles R. Crawley, Ian R. Judson, Mark Verrill, Catherine Hill, Florence I. Raynaud
Purpose. The study was performed to assess the antitumour activity and toxicity of a 72-h continuous infusion of single-agent etoposide as second-line treatment for patients with locally advanced or...
A Phase I/II Study of a 72-h Continuous Infusion of Etoposide in Advanced Soft Tissue Sarcoma (1997)
Charles R. Crawley, Ian R. Judson, Mark Verrill, Catherine Hill, Florence I. Raynaud
Purpose. The study was performed to assess the antitumour activity and toxicity of a 72-h continuous infusion of single-agent etoposide as second-line treatment for patients with locally advanced or...
Chung, Yuen-Li, Troy, Helen, Kristeleit, Rebecca, Aherne, Wynne, Jackson, L Elizabeth, Atadja, Peter, ...
The aim of this work was to use phosphorus magnetic resonance spectroscopy (31P MRS) to investigate the pharmacodynamic effects of LAQ824, a histone deacetylase (HDAC) inhibitor. Human HT29 colon...
A Phase I/II Study of a 72-h Continuous Infusion of Etoposide in Advanced Soft Tissue Sarcoma
Crawley, Charles R., Judson, Ian R., Verrill, Mark, Hill, Catherine, Raynaud, Florence I.
Purpose. The study was performed to assess the antitumour activity and toxicity of a 72-h continuous infusion of single-agent etoposide as second-line treatment for patients with locally advanced or...
Verrill, Mark W., Coley, Helen M., Judson, Ian R., Fisher, Cyril
Purpose. Deep fibromatoses are large, often rapidly growing but benign soft tissue tumours. Although surgery is the mainstay of treatment, in unremitting and aggressive cases the use of cytotoxic...
Spurrell, Emma L., Yeo, Yen C., Rollason, Terence P., Judson, Ian R.
Purpose:To discuss a case of ovarian fibromatosis/massive ovarian oedema, intra-abdominal fibromatosis, sclerosing peritonitis and Meig's syndrome. To review the reported therapeutic options.