Idoya Lahortiga

Duplication of the MYB oncogene in T-cell acute lymphoblastic leukemia (2007)

Lahortiga, Idoya, De Keersmaecker, Kim, Van Vlierberghe, Pieter, Graux, C, Cauwelier, B, Lambert, Frédéric, ...

12th Congress of the European Hematology Association Vienna

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia (2007)

Lahortiga, Idoya, De Keersmaecker, Kim, Van Vlierberghe, Pieter, Graux, C, Cauwelier, B, Lambert, Frédéric, ...

We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in five T-ALL cell lines. The duplication is associated with a threefold...

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia (2007)

Lahortiga, Idoya, De Keersmaecker, Kim, Van Vlierberghe, Pieter, Graux, Carlos, Cauwelier, Barbara, Lambert, Frederic, ...

We identified a duplication of the MYB oncogene in 8.4% of individuals with T cell acute lymphoblastic leukemia (T-ALL) and in five T-ALL cell lines. The duplication is associated with a threefold...

NIN, a gene encoding a CEP110-like centrosomal protein, is fused to PDGFRB in a patient with a t(5;14)(q33;q24) and an imatinib-responsive myeloproliferative disorder (2004)

Vizmanos, José, Novo, Francisco J., Roman, José P., Baxter, E. Joanna, Lahortiga, Idoya, Larrayoz, María J., ...

We describe a new PDGFRB fusion associated with a t(5;14)(q33;q24) in a patient with a longstanding chronic myeloproliferative disorder with eosinophilia. After confirmation of PDGFRB involvement and...

Novel translocations that disrupt the platelet-derived growth factor receptor beta (PDGFRB) gene in BCR-ABL-negative chronic myeloproliferative disorders (2003)

Baxter, E. Joanna, Kulkarni, Shashikant, Vizmanos, José-Luis, Jaju, Rina, Martinelli, Giovanni, Testoni, Nicoletta, ...

The BCR-ABL-negative chronic myeloproliferative disorders (CMPD) and myelodysplastic/myeloproliferative diseases (MDS/MPD) are a spectrum of related conditions for which the molecular pathogenesis is...

Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice

Shing, Danielle C., Trubia, Maurizio, Marchesi, Francesco, Radaelli, Enrico, Belloni, Elena, Tapinassi, Cinzia, ...

Transgenic expression of the abnormal products of acute myeloid leukemia–associated (AML-associated) primary chromosomal translocations in hematopoietic stem/progenitor cells initiates...