Igor Bačík

CD4 Glycoprotein Degradation Induced by Human Immunodeficiency Virus Type 1 Vpu Protein Requires the Function of Proteasomes and the Ubiquitin-Conjugating Pathway

Schubert, Ulrich, Antón, Luis C., Bačík, Igor, Cox, Josephine H., Bour, Stéphane, Bennink, Jack R., ...

The human immunodeficiency virus type 1 (HIV-1) vpu gene encodes a type I anchored integral membrane phosphoprotein with two independent functions. First, it regulates virus release from a...

CD4 Glycoprotein Degradation Induced by Human Immunodeficiency Virus Type 1 Vpu Protein Requires the Function of Proteasomes and the Ubiquitin-Conjugating Pathway

Schubert, Ulrich, Antón, Luis C., Bačík, Igor, Cox, Josephine H., Bour, Stéphane, Bennink, Jack R., ...

The human immunodeficiency virus type 1 (HIV-1) vpu gene encodes a type I anchored integral membrane phosphoprotein with two independent functions. First, it regulates virus release from a...

Introduction of a Glycosylation Site into a Secreted Protein Provides Evidence for an Alternative Antigen Processing Pathway: Transport of Precursors of Major Histocompatability Complex Class I–Restricted Peptides from the Endoplasmic Reticulum to the Cytosol

Bačík, Igor, Snyder, Heidi Link, Antón, Luis C., Russ, Gustav, Chen, Weisan, Bennink, Jack R., ...

We found that the presentation of a H-2Kd-restricted determinant from influenza virus nucleoprotein (NP) to T cells is strictly dependent on expression of the transporter associated with antigen...

Two Novel Routes of Transporter Associated with Antigen Processing (TAP)-independent Major Histocompatibility Complex Class I Antigen Processing

Snyder, Heidi Link, Bačík, Igor, Bennink, Jack R., Kearns, Grainne, Behrens, Timothy W., Bächi, Thomas, ...

Jaw1 is an endoplasmic reticulum (ER) resident protein representative of a class of proteins post translationally inserted into membranes via a type II membrane anchor (cytosolic NH2 domain, lumenal...