Identifying promoter features of co-regulated genes with similar network motifs (2009)
Harari, Oscar, Del Val, Coral, Romero-Zaliz, Rocío, Shin, Dongwoo, Huang, Henry, Groisman, Eduardo A, ...
Abstract Background A large amount of computational and experimental work has been devoted to uncovering network motifs in gene regulatory networks. The leading hypothesis is that evolutionary...
Profile analysis and prediction of tissue-specific CpG island methylation classes (2009)
Previti, Christopher, Harari, Oscar, Zwir, Igor, Del Val, Coral
Abstract Background The computational prediction of DNA methylation has become an important topic in the recent years due to its role in the epigenetic control of normal and cancer-related processes....
Different Proposals To Improve The Accuracy Of Fuzzy Linguistic Modeling (2007)
Oscar Cordón, Francisco Herrera, Pedro Villar, Igor Zwir
Nowadays, Linguistic Modeling is considered one of the most important applications of Fuzzy Set Theory, along with Fuzzy Control. Linguistic models have the advantage of providing a human-readable...
Zwir, Igor, Huang, Henry, Groisman, Eduardo A.
Motivation: A critical challenge of the post-genomic era is to understand how genes are differentially regulated even when they belong to a given network. Because the fundamental mechanism...
Zwir, Igor, Huang, Henry, Groisman, Eduardo A.
Motivation: A critical challenge of the postgenomic era is to understand how genes are differentially regulated even when they belong to a given network. Because the fundamental mechanism controlling...
Dissecting the PhoP regulatory network of Escherichia coli and Salmonella enterica
Zwir, Igor, Shin, Dongwoo, Kato, Akinori, Nishino, Kunihiko, Latifi, Tammy, Solomon, Felix, ...
Genetic and genomic approaches have been successfully used to assign genes to distinct regulatory networks. However, the present challenge of distinguishing differentially regulated genes within a...
Evolution of a Bacterial Regulon Controlling Virulence and Mg2+ Homeostasis
Perez, J. Christian, Shin, Dongwoo, Zwir, Igor, Latifi, Tammy, Hadley, Tricia J., Groisman, Eduardo A.
Related organisms typically rely on orthologous regulatory proteins to respond to a given signal. However, the extent to which (or even if) the targets of shared regulatory proteins are maintained...