Picking single-nucleotide polymorphisms in forests (2007)
Schwarz, Daniel F, Szymczak, Silke, Ziegler, Andreas, König, Inke R
Abstract With the development of high-throughput single-nucleotide polymorphism (SNP) technologies, the vast number of SNPs in smaller samples poses a challenge to the application of classical...
Genome-Wide Linkage Analysis of Malaria Infection Intensity and Mild Disease (2007)
Christian Timmann, Jennifer A. Evans, Inke R. König, André Kleensang, Franz Rüschendorf, Julia Lenzen, ...
Although balancing selection with the sickle-cell trait and other red blood cell disorders has emphasized the interaction between malaria and human genetics, no systematic approach has so far been...
An incremental procedure model for e-learning projects at universities (2006)
Pahlke, Friedrich, König, Inke R., Bischoff, Michael, Ziegler, Andreas
E-learning projects at universities are produced under different conditions than in industry. The main characteristic of many university projects is that these are realized quasi in a solo effort. In...
Kleensang, Andre, Franke, Daniel, König, Inke R, Ziegler, Andreas
Abstract Haplotype-based methods have become increasingly popular in the last decade because shared lengths in haplotypes can be used for disease localization. In this contribution, we propose a...
Blankenburg, Sandra, König, Inke R., Moessner, Rotraut, Laspe, Petra, Thoms, Kai-Martin, Krueger, Ullrich, ...
Individuals with the rare DNA repair deficiency syndrome xeroderma pigmentosum (XP) are sun-sensitive and exhibit a 1000-fold increased risk for developing skin cancers including cutaneous melanoma....
Blankenburg, Sandra, König, Inke R., Moessner, Rotraut, Laspe, Petra, Thoms, Kai-Martin, Krueger, Ullrich, ...
Individuals with the rare DNA repair deficiency syndrome xeroderma pigmentosum (XP) are sensitive to the sun and exhibit a 1000-fold increased risk for developing skin cancers, including cutaneous...
Fitze, Guido, Appelt, Hella, König, Inke R., Görgens, Heike, Stein, Ulrike, Walther, Wolfgang, ...
The activation of the RET signaling pathway during embryogenesis is a crucial prerequisite for a directional migration of enteric nervous system progenitor cells. Loss-of-function germline mutations...
Fitze, Guido, Appelt, Hella, König, Inke R., Görgens, Heike, Stein, Ulrike, Walther, Wolfgang, ...
The activation of the RET signaling pathway during embryogenesis is a crucial prerequisite for a directional migration of enteric nervous system progenitor cells. Loss-of-function germline mutations...
Fitze, Guido, Appelt, Hella, König, Inke R., Görgens, Heike, Stein, Ulrike, Walther, Wolfgang, ...
The activation of the RET signaling pathway during embryogenesis is a crucial prerequisite for a directional migration of enteric nervous system progenitor cells. Loss-of-function germline mutations...
König, Inke R., Schäfer, Helmut, Müller, Hans-Helge, Ziegler, Andreas
The study of genetic linkage or association in complex traits requires large sample sizes, as the expected effect sizes are small and extremely low significance levels need to be adopted. One...
Strong Genetic Evidence of DCDC2 as a Susceptibility Gene for Dyslexia
Schumacher, Johannes, Anthoni, Heidi, Dahdouh, Faten, König, Inke R., Hillmer, Axel M., Kluck, Nadine, ...
We searched for linkage disequilibrium (LD) in 137 triads with dyslexia, using markers that span the most-replicated dyslexia susceptibility region on 6p21-p22, and found association between the...
König, Inke R., Schäfer, Helmut, Müller, Hans-Helge, Ziegler, Andreas
The study of genetic linkage or association in complex traits requires large sample sizes, as the expected effect sizes are small and extremely low significance levels need to be adopted. One...
Strong Genetic Evidence of DCDC2 as a Susceptibility Gene for Dyslexia
Schumacher, Johannes, Anthoni, Heidi, Dahdouh, Faten, König, Inke R., Hillmer, Axel M., Kluck, Nadine, ...
We searched for linkage disequilibrium (LD) in 137 triads with dyslexia, using markers that span the most-replicated dyslexia susceptibility region on 6p21-p22, and found association between the...
Genome-Wide Linkage Analysis of Malaria Infection Intensity and Mild Disease
Timmann, Christian, Evans, Jennifer A, König, Inke R, Kleensang, André, Rüschendorf, Franz, Lenzen, Julia, ...
Although balancing selection with the sickle-cell trait and other red blood cell disorders has emphasized the interaction between malaria and human genetics, no systematic approach has so far been...
Picking single-nucleotide polymorphisms in forests
Schwarz, Daniel F, Szymczak, Silke, Ziegler, Andreas, König, Inke R
With the development of high-throughput single-nucleotide polymorphism (SNP) technologies, the vast number of SNPs in smaller samples poses a challenge to the application of classical statistical...
Linsel-Nitschke, Patrick, Götz, Anika, Erdmann, Jeanette, Braenne, Ingrid, Braund, Peter, Hengstenberg, Christian, ...
Linsel-Nitschke, Patrick, Götz, Anika, Erdmann, Jeanette, Braenne, Ingrid, Braund, Peter, Hengstenberg, Christian, ...
Analysis of a functional serotonin transporter promoter polymorphism in psoriasis vulgaris
Mössner, Rotraut, Stiens, Gerthild, König, Inke R., Schmidt, Diane, Platzer, Anja, Krüger, Ullrich, ...
Serotonin is a monoamine acting as a neuromediator in the central and peripheral nervous system. Recently, serotonin has also been shown to influence T- and B-cell function. The serotonin transporter...
Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations
Hicks, Andrew A., Pramstaller, Peter P., Johansson, Åsa, Vitart, Veronique, Rudan, Igor, Ugocsai, Peter, ...
Sphingolipids have essential roles as structural components of cell membranes and in cell signalling, and disruption of their metabolism causes several diseases, with diverse neurological,...