Ioannis Panagopoulos

Expression levels of HMGA2in adipocytic tumors correlate with morphologic and cytogenetic subgroups (2009)

Bartuma, Hammurabi, Panagopoulos, Ioannis, Collin, Anna, Trombetta, Domenico, Domanski, Henryk A, Mandahl, Nils, ...

Abstract Background The HMGA2 gene encodes a protein that alters chromatin structure. Deregulation, typically through chromosomal rearrangements, of HMGA2 has an important role in the development of...

Bone marrow ectopic expression of a non-coding RNA in childhood T-cell acute lymphoblastic leukemia with a novel t(2;11)(q11.2;p15.1) translocation (2008)

Guastadisegni, Maria, Lonoce, Angelo, Impera, Luciana, Albano, Francesco, D'Addabbo, Pietro, Caruso, Sebastiano, ...

Abstract Chromosomal translocations play a crucial role in tumorigenesis, often resulting in the formation of chimeric genes or in gene deregulation through position effects. T-cell acute...

Behavioral Synthesis with SystemC (2008)

George Economakos, Petros Oikonomakos, Ioannis Panagopoulos, Ioannis Poulakis, George Papakonstantinou

Having to cope with the continuously increasing complexity of modern digital systems, hardware designers are considering more and more seriously language based methodologies for parts of their...

Index Terms—FPGA Design, Diophantine equation (2008)

Ioannis Panagopoulos, Christos Pavlatos, Ros Dimopoulos, George Papakonstantinou

Abstract-- In this paper we present the theoretical framework for enumerating the solutions of the first order Diophantine equation with unitary coefficients that helps us to define the sets of...

A Comparative Evaluation of Models and Specification Languages for Embedded System Design ♠ (2008)

Ioannis Panagopoulos, George Papakonstantinou, Nikitas Alex

Abstract. The HW/SW Codesign approach in the design of embedded systems and their increasing complexity has turned the need of simplifying the specification of both the desired behaviour and the...

Behavioral Synthesis with SystemC (2007)

George Economakos, Petros Oikonomakos, Ioannis Panagopoulos, Ioannis Poulakis, George Papakonstantinou

Having to cope with the continuously increasing complexity of modern digital systems, hardware designers are considering more and more seriously language based methodologies for parts of their...

clustered near-centromeric breakpoints and overexpression of genes (2007)

Josef Davidsson, Anna Andersson, Kajsa Paulsson, Markus Heidenblad, Åke Borg, Jesper Heldrup, ...

Tiling resolution array CGH, expression, and methylation analyses of dup(1q) in Burkitt

Midline carcinoma with t(15;19) and BRD4-NUTfusion oncogene in a 30-year-old female with response to docetaxel and radiotherapy (2006)

Engleson, Jens, Soller, Maria, Panagopoulos, Ioannis, Dahlén, Anna, Dictor, Michael, Jerkeman, Mats

Abstract Background Poorly differentiated midline carcinoma with a translocation between chromosomes 15 and 19, i.e. t(15;19), has been recognized as a distinct clinical entity for over a decade....

Rearrangement of the COL12A1 and COL4A5 genes in subungual exostosis: molecular cytogenetic delineation of the tumor-specific translocation t(X;6)(q13-14;q22) (2006)

Panagopoulos, Ioannis, Mandahl, Nils, Mertens, Fredrik, ...

Subungual exostosis is a benign bone- and cartilage-producing tumor occurring in the hands and feet of children and young adults. The recent identification of a recurrent chromosomal translocation...

Clinicopathologic and molecular genetic characterization of low-grade fibromyxoid sarcoma, and cloning of a novel FUS/CREB3L1 fusion gene (2005)

Fletcher, Christopher D M, Antonescu, Cristina R, Coindre, Jean-Michel, Colecchia, Maurizio, Domanski, Henryk A, ...

Low-grade fibromyxoid sarcoma (LGFMS) is an indolent, late-metastasizing malignant soft-tissue tumor that is often mistaken for either more benign or more malignant tumor types. Cytogenetic analyses...

Activation of the GLI oncogene through fusion with the beta-actin gene (ACTB) in a group of distinctive pericytic neoplasms: pericytoma with t(7;12) (2004)

Fletcher, Christopher D M, Mertens, Fredrik, Fletcher, Jonathan A, Perez-Atayde, Antonio R, Hicks, M John, ...

Activation of the GLI oncogene is an important step in the sonic hedgehog signaling pathway, and leads to, eg, tissue-specific cell proliferation during embryogenesis. GLI activity in adult tissues...

Vascular endothelial growth factor gene polymorphisms and pre-eclampsia (2004)

Papazoglou, Dimitrios, Galazios, Georgios, Koukourakis, Michael I., Panagopoulos, Ioannis, Kontomanolis, Emmanuel N., Papatheodorou, Konstantinos, ...

Vascular endothelial growth factor (VEGF) plays a crucial role in physiological vasculogenesis and vascular permeability and has been implicated in the pathogenesis of pre-eclampsia. Our present...

Vascular endothelial growth factor gene polymorphisms and pre-eclampsia (2004)

Papazoglou, Dimitrios, Galazios, Georgios, Koukourakis, Michael I., Panagopoulos, Ioannis, Kontomanolis, Emmanuel N., Papatheodorou, Konstantinos, ...

Vascular endothelial growth factor (VEGF) plays a crucial role in physiological vasculogenesis and vascular permeability and has been implicated in the pathogenesis of pre‐eclampsia. Our present...

Vascular endothelial growth factor gene polymorphisms and pre-eclampsia (2004)

Papazoglou, Dimitrios, Galazios, Georgios, Koukourakis, Michael I., Panagopoulos, Ioannis, Kontomanolis, Emmanuel N., Papatheodorou, Konstantinos, ...

Vascular endothelial growth factor (VEGF) plays a crucial role in physiological vasculogenesis and vascular permeability and has been implicated in the pathogenesis of pre-eclampsia. Our present...

Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma (2003)

Storlazzi, Clelia Tiziana, Mertens, Fredrik, Nascimento, Antonio, Isaksson, Margareth, Wejde, Johan, Brosjö, Otte, ...

The FUSgene at 16p11 fuses with DDIT3and ATF1 as the result of translocations with chromosome band 12q13 in myxoid liposarcoma and angiomatoid fibrous histiocytoma, respectively, and with ERG as the...

Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma (2003)

Storlazzi, Clelia Tiziana, Mertens, Fredrik, Nascimento, Antonio, Isaksson, Margareth, Wejde, Johan, Brosjö, Otte, ...

The FUS gene at 16p11 fuses with DDIT3 and ATF1 as the result of translocations with chromosome band 12q13 in myxoid liposarcoma and angiomatoid fibrous histiocytoma, respectively, and with ERG as...

Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma (2003)

Storlazzi, Clelia Tiziana, Mertens, Fredrik, Nascimento, Antonio, Isaksson, Margareth, Wejde, Johan, Brosjö, Otte, ...

The FUSgene at 16p11 fuses with DDIT3and ATF1 as the result of translocations with chromosome band 12q13 in myxoid liposarcoma and angiomatoid fibrous histiocytoma, respectively, and with ERG as the...

Expression of NUP98/TOP1, but not of TOP1/NUP98, in a treatment-related myelodysplastic syndrome with t(10;20;11)(q24;q11;p15). (2002)

Panagopoulos, Ioannis, Fioretos, Thoas, Isaksson, Margareth, Larsson, Gun, Billström, Rolf, Mitelman, Felix, ...

The t(11;20)(p15;q11) is a rare but recurrent translocation that so far has been described in only four acute myeloid leukemias (AMLs), two treatment-related myelodysplastic syndromes (t-MDSs), and...

Molecular genetic characterization of the EWS/ATF1 fusion gene in clear cell sarcoma of tendons and aponeuroses. (2002)

Panagopoulos, Ioannis, Mertens, Fredrik, Dêbiec-Rychter, Maria, Isaksson, Margareth, Limon, Janusz, Kardas, Iwona, ...

Clear cell sarcoma (CCS) is a rare malignant soft tissue tumor particularly associated with tendons and aponeuroses. The cytogenetic hallmark is the translocation t(12;22)(q13;q12) resulting in a...

Fusion of RDC1 with HMGA2 in lipomas as the result of chromosome aberrations involving 2q35-37 and 12q13-15. (2002)

Broberg, Karin, Zhang, Miao, Strombeck, Bodil, Isaksson, Margareth, Nilsson, Malin, Mertens, Fredrik, ...

Rearrangements of chromosome bands 12q13-15 are frequent in various benign mesenchymal and epithelial tumors, and the gene HMGA2 seems to be the most common target within this chromosome region. In...

Molecular genetic characterization of the EWS/CHN and RBP56/CHN fusion genes in extraskeletal myxoid chondrosarcoma. (2002)

Panagopoulos, Ioannis, Mertens, Fredrik, Isaksson, Margareth, Domanski, Henryk A, Brosjö, Otte, Heim, Sverre, ...

Extraskeletal myxoid chondrosarcoma (EMC) is a soft-tissue neoplasm cytogenetically characterized by the translocations t(9;22)(q22;q11-12) or t(9;17)(q22;q11), generating EWS/CHN or RBP56/CHN fusion...

Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13) (2001)

Panagopoulos, Ioannis, Fioretos, Thoas, Isaksson, Margareth, Samuelsson, Ulf, Billström, Rolf, Strömbeck, Bodil, ...

The CBP gene at 16p13 fuses to MOZ and MLL as a result of the t(8;16)(p11;p13) in acute (myelo)monocytic leukemias (AML M4/M5) and the t(11;16)(q23;p13) in treatment-related AML, respectively. We...

Advances in Attribute Grammar Driven Hardware Compilation (2000)

George Economakos, Ioannis Panagopoulos, George Papakonstantinou

High-level or behavioral synthesis of digital circuits offers an effective way to deal with the increasing complexity of digital hardware design. A high-level synthesis tool transforms an abstract...

Response of sugar beet plants to ultraviolet-B (280-320 nm) radiation and Cercospora leaf spot disease (1992)

Panagopoulos, Ioannis, Bornman, Janet F., Björn, Lars Olof

Sugar beet (Beta vulgaris L.) plants injected with Cercospora beticola Sacc. as well as non-infected plants were grown under visible light with or without ultraviolet-B (UV-B, 280-320 nm) radiation...

Effects of ultraviolet radiation and visible light on growth, fluorescence induction, ultraweak luminescence and peroxidase activity in sugar beet plants (1990)

Panagopoulos, Ioannis, Bornman, Janet F., Björn, Lars Olof

Experiments were conducted under growth chamber conditions in order to investigate the importance of the background light quality for the effect of UVB (280–320 nm) radiation on plants. Three...

Lentivirus Vector Gene Expression during ES Cell-Derived Hematopoietic Development In Vitro

Hamaguchi, Isao, Woods, Niels-Bjarne, Panagopoulos, Ioannis, Andersson, Elisabet, Mikkola, Hanna, Fahlman, Cecilia, ...

The murine embryonal stem (ES) cell virus (MESV) can express transgenes from the long terminal repeat (LTR) promoter/enhancer in undifferentiated ES cells, but expression is turned off upon...

Fusion of the Tumor-Suppressor Gene CHEK2 and the Gene for the Regulatory Subunit B of Protein Phosphatase 2 PPP2R2A in Childhood Teratoma1

Jin, Yuesheng, Mertens, Fredrik, Kullendorff, Carl-Magnus, Panagopoulos, Ioannis

We characterized the molecular genetic consequences of a balanced chromosome translocation t(8;22)(p21;q12) which occurred as the sole cytogenetic aberration in short-term cultured cells from an...

Lentivirus Vector Gene Expression during ES Cell-Derived Hematopoietic Development In Vitro

Hamaguchi, Isao, Woods, Niels-Bjarne, Panagopoulos, Ioannis, Andersson, Elisabet, Mikkola, Hanna, Fahlman, Cecilia, ...

The murine embryonal stem (ES) cell virus (MESV) can express transgenes from the long terminal repeat (LTR) promoter/enhancer in undifferentiated ES cells, but expression is turned off upon...

Fusion of the Tumor-Suppressor Gene CHEK2 and the Gene for the Regulatory Subunit B of Protein Phosphatase 2 PPP2R2A in Childhood Teratoma1

Jin, Yuesheng, Mertens, Fredrik, Kullendorff, Carl-Magnus, Panagopoulos, Ioannis

We characterized the molecular genetic consequences of a balanced chromosome translocation t(8;22)(p21;q12) which occurred as the sole cytogenetic aberration in short-term cultured cells from an...

Activation of the GLI Oncogene through Fusion with the β-Actin Gene (ACTB) in a Group of Distinctive Pericytic Neoplasms: Pericytoma with t(7;12)

Dahlén, Anna, Fletcher, Christopher D. M., Mertens, Fredrik, Fletcher, Jonathan A., Perez-Atayde, Antonio R., Hicks, M. John, ...

Activation of the GLI oncogene is an important step in the sonic hedgehog signaling pathway, and leads to, eg, tissue-specific cell proliferation during embryogenesis. GLI activity in adult tissues...

Bone marrow ectopic expression of a non-coding RNA in childhood T-cell acute lymphoblastic leukemia with a novel t(2;11)(q11.2;p15.1) translocation

Guastadisegni, Maria Corsignano, Lonoce, Angelo, Impera, Luciana, Albano, Francesco, D'Addabbo, Pietro, Caruso, Sebastiano, ...

Chromosomal translocations play a crucial role in tumorigenesis, often resulting in the formation of chimeric genes or in gene deregulation through position effects. T-cell acute lymphoblastic...