Ionel Sandovici

Human Imprinted Chromosomal Regions Are Historical Hot-Spots of Recombination (2006)

Ionel Sandovici, Sacha Kassovska-Bratinova, Joe E. Vaughan, Rae Stewart, Mark Leppert, Carmen Sapienza

Human recombination rates vary along the chromosomes as well as between the two sexes. There is growing evidence that epigenetic factors may have an important influence on recombination rates, as...

Human Imprinted Chromosomal Regions are Historical Hot-Spots of Recombination (2006)

Ionel Sandovici, Sacha Kassovska-Bratinova, Joe E Vaughan, Rae Stewart, Mark Leppert, Carmen Sapienza

Human recombination rates vary along the chromosomes as well as between the two sexes. There is growing evidence that epigenetic factors may have an important influence on recombination rates, as...

Interindividual variability and parent of origin DNA methylation differences at specific human Alu elements (2005)

Sandovici, Ionel, Kassovska-Bratinova, Sacha, Loredo-Osti, J. Concepción, Leppert, Mark, Suarez, Alexander, Stewart, Rae, ...

We investigated the CpG methylation of 19 specific members of Alu sub-families in human DNA isolated from whole blood, using an assay based on methylation-sensitive restriction endonuclease digestion...

Interindividual variability and parent of origin DNA methylation differences at specific human Alu elements (2005)

Sandovici, Ionel, Kassovska-Bratinova, Sacha, Leppert, Mark, Suarez, Alexander, Stewart, Rae, ...

We investigated the CpG methylation of 19 specific members of Alu subfamilies in human DNA isolated from whole blood, using an assay based on methylation-sensitive restriction endonuclease digestion...

Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions (2004)

Sandovici, Ionel, Leppert, Mark, Hawk, Patricia Red, Suarez, Alexander, Linares, Yendi, Sapienza, Carmen

Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions (2003)

Sandovici, Ionel, Leppert, Mark, Hawk, Patricia Red, Suarez, Alexander, Linares, Yendi, Sapienza, Carmen

Loss of imprinting (LOI) has been observed in many types of human tumors and may be a predisposing event in some colon cancers. LOI is strongly associated with alteration of normal DNA methylation...

Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems

Constância, Miguel, Angiolini, Emily, Sandovici, Ionel, Smith, Paul, Smith, Rachel, Kelsey, Gavin, ...

The mammalian fetus is unique in its dependence during gestation on the supply of maternal nutrients through the placenta. Maternal supply and fetal demand for nutrients need to be fine tuned for...

Human Imprinted Chromosomal Regions Are Historical Hot-Spots of Recombination

Sandovici, Ionel, Kassovska-Bratinova, Sacha, Vaughan, Joe E, Stewart, Rae, Leppert, Mark, Sapienza, Carmen

Human recombination rates vary along the chromosomes as well as between the two sexes. There is growing evidence that epigenetic factors may have an important influence on recombination rates, as...

Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems

Constância, Miguel, Angiolini, Emily, Sandovici, Ionel, Smith, Paul, Smith, Rachel, Kelsey, Gavin, ...

The mammalian fetus is unique in its dependence during gestation on the supply of maternal nutrients through the placenta. Maternal supply and fetal demand for nutrients need to be fine tuned for...

Human Imprinted Chromosomal Regions Are Historical Hot-Spots of Recombination

Sandovici, Ionel, Kassovska-Bratinova, Sacha, Vaughan, Joe E, Stewart, Rae, Leppert, Mark, Sapienza, Carmen

Human recombination rates vary along the chromosomes as well as between the two sexes. There is growing evidence that epigenetic factors may have an important influence on recombination rates, as...