Irina Khrebtukova, Christian D. Haudenschild, Daixing Zhou, Selene M. Virk, Maria Johnson, Keith Moon, ...
It is generally believed that the first step toward systems biology is to construct a comprehensive expression database that catalogs all the mRNA and regulatory RNA in a sample and documents their...
Accurate whole human genome sequencing using reversible terminator chemistry (2008)
Bentley, David R., Balasubramanian, Shankar, Swerdlow, Harold P., Smith, Geoffrey P., Milton, John, Brown, Clive G., ...
DNA sequence information underpins genetic research, enabling discoveries of important biological or medical benefit. Sequencing projects have traditionally used long (400-800 base pair) reads, but...
An atlas of human gene expression from massively parallel signature sequencing (MPSS) (2005)
Jongeneel, C. Victor, Delorenzi, Mauro, Iseli, Christian, Zhou, Daixing, Haudenschild, Christian D., Khrebtukova, Irina, ...
We have used massively parallel signature sequencing (MPSS) to sample the transcriptomes of 32 normal human tissues to an unprecedented depth, thus documenting the patterns of expression of almost...
MPSS profiling of human embryonic stem cells (2004)
Brandenberger, Ralph, Khrebtukova, Irina, Thies, R Scott, Miura, Takumi, Jingli, Cai, Puri, Raj, ...
Abstract Background Pooled human embryonic stem cells (hESC) cell lines were profiled to obtain a comprehensive list of genes common to undifferentiated human embryonic stem cells. Results Pooled...
Khrebtukova, Irina, Spreitzer, Robert J.
Ribulose-1,5-bisphosphate carboxylase/oxygenase (EC 4.1.1.39) is the key photosynthetic enzyme that catalyzes the first step of CO2 fixation. The chloroplast-localized holoenzyme of plants and green...
MPSS profiling of human embryonic stem cells
Brandenberger, Ralph, Khrebtukova, Irina, Thies, R Scott, Miura, Takumi, Jingli, Cai, Puri, Raj, ...
An atlas of human gene expression from massively parallel signature sequencing (MPSS)
Jongeneel, C. Victor, Delorenzi, Mauro, Iseli, Christian, Zhou, Daixing, Haudenschild, Christian D., Khrebtukova, Irina, ...
We have used massively parallel signature sequencing (MPSS) to sample the transcriptomes of 32 normal human tissues to an unprecedented depth, thus documenting the patterns of expression of almost...
Khrebtukova, Irina, Spreitzer, Robert J.
Ribulose-1,5-bisphosphate carboxylase/oxygenase (EC 4.1.1.39) is the key photosynthetic enzyme that catalyzes the first step of CO2 fixation. The chloroplast-localized holoenzyme of plants and green...
MPSS profiling of human embryonic stem cells
Brandenberger, Ralph, Khrebtukova, Irina, Thies, R Scott, Miura, Takumi, Jingli, Cai, Puri, Raj, ...
An atlas of human gene expression from massively parallel signature sequencing (MPSS)
Jongeneel, C. Victor, Delorenzi, Mauro, Iseli, Christian, Zhou, Daixing, Haudenschild, Christian D., Khrebtukova, Irina, ...
We have used massively parallel signature sequencing (MPSS) to sample the transcriptomes of 32 normal human tissues to an unprecedented depth, thus documenting the patterns of expression of almost...
Mudge, Joann, Miller, Neil A., Khrebtukova, Irina, Lindquist, Ingrid E., May, Gregory D., Huntley, Jim J., ...
Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we...
Ab initio construction of a eukaryotic transcriptome by massively parallel mRNA sequencing
Yassour, Moran, Kaplan, Tommy, Fraser, Hunter B., Levin, Joshua Z., Pfiffner, Jenna, Adiconis, Xian, ...
Defining the transcriptome, the repertoire of transcribed regions encoded in the genome, is a challenging experimental task. Current approaches, relying on sequencing of ESTs or cDNA libraries, are...
Chimeric transcript discovery by paired-end transcriptome sequencing
Maher, Christopher A., Palanisamy, Nallasivam, Brenner, John C., Cao, Xuhong, Kalyana-Sundaram, Shanker, Luo, Shujun, ...
Recurrent gene fusions are a prevalent class of mutations arising from the juxtaposition of 2 distinct regions, which can generate novel functional transcripts that could serve as valuable...