Irma Sánchez-Vargas

Dengue virus type 2: replication and tropisms in orally infected Aedes aegyptimosquitoes (2007)

Salazar, Ma Isabel, Richardson, Jason H, Sánchez-Vargas, Irma, Olson, Ken E, Beaty, Barry J

Abstract Background To be transmitted by its mosquito vector, dengue virus (DENV) must infect midgut epithelial cells, replicate and disseminate into the hemocoel, and finally infect the salivary...

La Crosse Bunyavirus Nonstructural Protein NSs Serves To Suppress the Type I Interferon System of Mammalian Hosts▿

Blakqori, Gjon, Delhaye, Sophie, Habjan, Matthias, Blair, Carol D., Sánchez-Vargas, Irma, Olson, Ken E., ...

La Crosse virus (LACV) is a mosquito-transmitted member of the Bunyaviridae family that causes severe encephalitis in children. For the LACV nonstructural protein NSs, previous overexpression studies...

Dengue Virus Type 2 Infections of Aedes aegypti Are Modulated by the Mosquito's RNA Interference Pathway

Sánchez-Vargas, Irma, Scott, Jaclyn C., Poole-Smith, B. Katherine, Franz, Alexander W. E., Barbosa-Solomieu, Valérie, Wilusz, Jeffrey, ...

A number of studies have shown that both innate and adaptive immune defense mechanisms greatly influence the course of human dengue virus (DENV) infections, but little is known about the innate...