Irma Sanchez-Vargas

RNA Silencing of Dengue Virus Type 2 Replication in Transformed C6/36 Mosquito Cells Transcribing an Inverted-Repeat RNA Derived from the Virus Genome

Adelman, Zach N., Sanchez-Vargas, Irma, Travanty, Emily A., Carlson, Jon O., Beaty, Barry J., Blair, Carol D., ...

Double-stranded RNA (dsRNA) initiates cellular posttranscriptional responses that are collectively called RNA silencing in a number of different organisms, including plants, nematodes, and fruit...

RNA interference acts as a natural antiviral response to O'nyong-nyong virus (Alphavirus; Togaviridae) infection of Anopheles gambiae

Keene, Kimberly M., Foy, Brian D., Sanchez-Vargas, Irma, Beaty, Barry J., Blair, Carol D., Olson, Ken E.

RNA interference (RNAi) is triggered in eukaryotic organisms by double-stranded RNA (dsRNA), and it destroys any mRNA that has sequence identity with the dsRNA trigger. The RNAi pathway in Anopheles...

Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti

Franz, Alexander W. E., Sanchez-Vargas, Irma, Adelman, Zach N., Blair, Carol D., Beaty, Barry J., James, Anthony A., ...

Mosquitoes (Aedes aegypti) were genetically modified to exhibit impaired vector competence for dengue type 2 viruses (DENV-2). We exploited the natural antiviral RNA interference (RNAi) pathway in...

RNA Silencing of Dengue Virus Type 2 Replication in Transformed C6/36 Mosquito Cells Transcribing an Inverted-Repeat RNA Derived from the Virus Genome

Adelman, Zach N., Sanchez-Vargas, Irma, Travanty, Emily A., Carlson, Jon O., Beaty, Barry J., Blair, Carol D., ...

Double-stranded RNA (dsRNA) initiates cellular posttranscriptional responses that are collectively called RNA silencing in a number of different organisms, including plants, nematodes, and fruit...

RNA interference acts as a natural antiviral response to O'nyong-nyong virus (Alphavirus; Togaviridae) infection of Anopheles gambiae

Keene, Kimberly M., Foy, Brian D., Sanchez-Vargas, Irma, Beaty, Barry J., Blair, Carol D., Olson, Ken E.

RNA interference (RNAi) is triggered in eukaryotic organisms by double-stranded RNA (dsRNA), and it destroys any mRNA that has sequence identity with the dsRNA trigger. The RNAi pathway in Anopheles...

Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti

Franz, Alexander W. E., Sanchez-Vargas, Irma, Adelman, Zach N., Blair, Carol D., Beaty, Barry J., James, Anthony A., ...

Mosquitoes (Aedes aegypti) were genetically modified to exhibit impaired vector competence for dengue type 2 viruses (DENV-2). We exploited the natural antiviral RNA interference (RNAi) pathway in...