BMC Psychiatry BMC 22002, Psychiatry Hypothesis (2007)
Hans W Moises, Tomas Zoega, Irving I Gottesman
The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia
Schizophrenia and psychotic symptoms in families of two American Indian tribes (2007)
Robin, Robert W, Gottesman, Irving I, Albaugh, Bernard, Goldman, David
Abstract Background The risk of schizophrenia is thought to be higher in population isolates that have recently been exposed to major and accelerated cultural change, accompanied by ensuing...
Braff, David L., Freedman, Robert, Schork, Nicholas J., Gottesman, Irving I.
The genetics of schizophrenia has been approached utilizing a variety of methods. One emerging strategy is the use of endophenotypes in order to understand and identify the functional importance of...
Thompson, William W, Gottesman, Irving I, Zalewski, Christine
Abstract Background Two large independent studies funded by the US government have assessed the impact of the Vietnam War on the prevalence of PTSD in US veterans. The National Vietnam Veterans...
Braff, David L., Freedman, Robert, Schork, Nicholas J., Gottesman, Irving I.
The genetics of schizophrenia has been approached utilizing a variety of methods. One emerging strategy is the use of endophenotypes in order to understand and identify the functional importance of...
BMC Psychiatry BioMed Central (2006)
William W Thompson, Irving I Gottesman, Christine Zalewski, Open Access
Research article Reconciling disparate prevalence rates of PTSD in large samples of US male Vietnam veterans and their controls
Theories of schizophrenia: a genetic-inflammatory-vascular synthesis (2005)
Hanson, Daniel R, Gottesman, Irving I
Abstract Background Schizophrenia, a relatively common psychiatric syndrome, affects virtually all brain functions yet has eluded explanation for more than 100 years. Whether by developmental and/or...
Daniel R Hanson, Irving I Gottesman, Daniel R Hanson, Irving I Gottesman
© 2005 Hanson and Gottesman; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Phenotypic differences in genetically identical organisms: the epigenetic perspective (2005)
Wong, Albert H.C., Gottesman, Irving I., Petronis, Arturas
Human monozygotic twins and other genetically identical organisms are almost always strikingly similar in appearance, yet they are often discordant for important phenotypes including complex...
Monozygotic Twins Exhibit Numerous Epigenetic Differences: Clues to Twin Discordance? (2003)
Petronis, Arturas, Gottesman, Irving I., Kan, Peixiang, Kennedy, James L., Basile, Vincenzo S., Paterson, Andrew D., ...
The goal of this pilot study was to explore the putative molecular mechanisms underlying the phenotypic discordance of monozygotic (MZ) twins. Thus, patterns of epigenetic DNA modification were...
The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia (2002)
Moises, Hans W, Zoega, Tomas, Gottesman, Irving I
Abstract Background A systems approach to understanding the etiology of schizophrenia requires a theory which is able to integrate genetic as well as neurodevelopmental factors. Presentation of the...
Moises, Hans W., Matthiasson, Pall, Zoega, Tomas, Jhala, Gaurang, Yang, Liu, Gottesman, Irving I., ...
This paper has been withdrawn by the authors, due to a possible bias in the twosome approach found by Dr. George Kirov. It seems that the bias has amplified an existing weak signal. The detection of...
Genes, Experience, and Chance in Schizophrenia--Positioning for the 21st Century (1997)
Moldin, Steven O., Gottesman, Irving I.
Genetic factors make important contributions to the etiologies of schizophrenia. The mode of familial inheritance remains unknown, but it is highly likely that multiple genes and idiosyncratic...
HIV/AIDS Risks as a Consequence of Schizophrenia (1997)
Gottesman, Irving I., Groome, Carol S.
Given both the rapid rise in the prevalence of HIV infection among adolescent and adult males (0.6%) and females (0.1%) in the United States from 1984 to 1992 and the associations among HIV,...
Negative Association Between Schizophrenia and Rheumatoid Arthritis (1991)
Vinogradov, Sophia, Gottesman, Irving I., Moises, Hans W., Nicol, Susan
Persuasive evidence has accumulated demonstrating a strong negative association between rheumatoid arthritis and schizophrenia at the population level. Explanations for this phenomenon have taken...
Schizophrenics Kill Themselves Too: A Review of Risk Factors for Suicide (1990)
Caldwell, Constance B., Gottesman, Irving I.
Suicide rates among schizophrenic individuals are disturbingly high. At present, suicide is the number one cause of premature death among schizophrenics, with 10 to 13 percent killing themselves....
Farmer, Anne, McGuffin, Peter, Gottesman, Irving I.
The authors defend the proposition that the simple division of schizophrenia into family history positive versus family history negative in the hope of uncovering etiological heterogeneity is too...
Vital Statistics, Demography, and Schizophrenia: Editor's Introduction (1989)
The Guest Editor introduces this Theme Issue of the Schizophrenia Bulletin with an overview of the kinds of subject matters appropriate for a comprehensive understanding of the vital statistics and...
Genetic Linkage in Schizophrenia: Perspectives From Genetic Epidemiology (1989)
McGue, Matthew, Gottesman, Irving I.
Research on the genetic epidemiology of schizophrenia is briefly and selectively reviewed. The following three salient features of schizophrenia that represent challenges to the design of linkage...
The psychotic hinterlands or the fringes of lunacy (1987)
The hinterlands of the major psychoses—schizophrenia and bipolar and unipolar affective disorders—are occupied by both unusual and quite ordinary individuals, only some of whom go on to a...
Gottesman, Irving I., McGuffin, Peter, Farmer, Anne E.
Although a decade has passed since the genetics of schizophrenia was examined for the Schizophrenia Bulletin, the epigenetic puzzle of schizophrenia has not yielded its secrets to any scientific...
Platelet MAO Activity: Relationships to Clinical and Psychometric Variables (1980)
Adler, Stephanie A., Gottesman, Irving I., Orsulak, Paul J., Kizuka, Patricia Platz, Schildkraut, Joseph J.
Platelet monoamine oxidase (MAO) activity was measured in a group of hospitalized male psychiatric patients. The findings of this study confirm previous reports of: (1) reduced platelet MAO activity...
The psychogenetics of personality--[microform] /--by Irving I. Gottesman. (1960)
Thesis (Ph. D.)--University of Minnesota, 1960.
Schizophrenia and psychotic symptoms in families of two American Indian tribes
Robin, Robert W, Gottesman, Irving I, Albaugh, Bernard, Goldman, David
Braff, David L., Freedman, Robert, Schork, Nicholas J., Gottesman, Irving I.
The genetics of schizophrenia has been approached utilizing a variety of methods. One emerging strategy is the use of endophenotypes in order to understand and identify the functional importance of...