Isabelle Goiffon

Dynamic remodelling of human 7SK snRNP controls the nuclear level of active P-TEFb

Van Herreweghe, Elodie, Egloff, Sylvain, Goiffon, Isabelle, Jády, Beáta E, Froment, Carine, Monsarrat, Bernard, ...

The 7SK small nuclear RNA (snRNA) regulates RNA polymerase II transcription elongation by controlling the protein kinase activity of the positive transcription elongation factor b (P-TEFb). In...