Effect of Diving and Diving Hoods on the Bacterial Flora of the External Ear Canal and Skin (2006)
Brook, Itzhak, Coolbaugh, James C., Williscroft, Robert G.
Pub. in Jnl. of Clinical Microbiology, v15 n5 p855-859, May 1982.
Brook, Itzhak, Hausfeld, Jeffrey N.
Objective: To evaluate the effects of subinhibitory concentrations of penicillin and telithromycin on capsular formation by Streptococcus pneumoniae. Methods: A total of 60 isolates of S. pneumoniae,...
Brook, Itzhak, Hausfeld, Jeffrey N.
Objective: To evaluate the effects of subinhibitory concentrations of penicillin and telithromycin on capsular formation by Streptococcus pneumoniae. Methods: A total of 60 isolates of S. pneumoniae,...
Microbiology and management of brain abscess in children (2004)
Brain abscess is an uncommon but serious life threatening infection in children. The infection can originate from contiguous sites of existing infections, such as chronic otitis media, dental...
Microbiology and management of brain abscess in children (2004)
Brain abscess is an uncommon but serious life threatening infection in children. The infection can originate from contiguous sites of existing infections, such as chronic otitis media, dental...
Microbiology and management of brain abscess in children (2004)
Brain abscess is an uncommon but serious life threatening infection in children. The infection can originate from contiguous sites of existing infections, such as chronic otitis media, dental...
Objective: To investigate the antimicrobial susceptibility of the organisms isolated from the nasopharynx of children who present with acute maxillary sinusitis (AMS) or maxillary sinusitis that...
Objective: To investigate the antimicrobial susceptibility of the organisms isolated from the nasopharynx of children who present with acute maxillary sinusitis (AMS) or maxillary sinusitis that...
Effects of antimicrobial therapy on the microbial flora of the adenoids (2003)
The core of the adenoids contains polymicrobial aerobic and anaerobic flora and also includes potential respiratory pathogens. Similar flora, although in higher numbers and with a higher frequency of...
Effects of antimicrobial therapy on the microbial flora of the adenoids (2003)
The core of the adenoids contains polymicrobial aerobic and anaerobic flora and also includes potential respiratory pathogens. Similar flora, although in higher numbers and with a higher frequency of...
Effects of antimicrobial therapy on the microbial flora of the adenoids (2003)
The core of the adenoids contains polymicrobial aerobic and anaerobic flora and also includes potential respiratory pathogens. Similar flora, although in higher numbers and with a higher frequency of...
Clinical review: Bacteremia caused by anaerobic bacteria in children (2002)
Abstract This review describes the microbiology, diagnosis and management of bacteremia caused by anaerobic bacteria in children. Bacteroides fragilis , Peptostreptococcus sp., Clostridium sp., and...
Microbiology of polymicrobial abscesses and implications for therapy (2002)
Abscesses that develop as a result of introduction of the normal flora into a normally sterile body site are often polymicrobial. This review summarizes past studies published by our group on the...
Microbiology of polymicrobial abscesses and implications for therapy (2002)
Abscesses that develop as a result of introduction of the normal flora into a normally sterile body site are often polymicrobial. This review summarizes past studies published by our group on the...
Effect of amoxicillin and co-amoxiclav on the aerobic and anaerobic nasopharyngeal flora (2002)
The effects of co-amoxiclav (AMC) and amoxicillin (AMX) therapy on the nasopharyngeal flora of children with acute otitis media (AOM) were compared. Nasopharyngeal culture for aerobic and anaerobic...
Microbiology of polymicrobial abscesses and implications for therapy (2002)
Abscesses that develop as a result of introduction of the normal flora into a normally sterile body site are often polymicrobial. This review summarizes past studies published by our group on the...
Effect of amoxycillin with or without clavulanate on adenoid bacterial flora (2001)
The effect of antimicrobial therapy with amoxycillin (AMX) or co-amoxiclav (AMC) on the adenoid bacterial flora of 45 children with recurrent otitis media (ROM), scheduled for elective adenoidectomy,...
Quinolone therapy in the prevention of endogenous and exogenous infection after irradiation (1994)
Brook, Itzhak, Ledney, G. David
The effect of oral therapy with 6 quinolones, lomefloxacin, ofloxacin, sparfloxacin, temafloxacin, CI-960, and CI-990 in the prevention of post-irradiation bacteraemia and mortality was tested in...
Brook, Itzhak, Ledney, G. David
The effects on the faecal flora and the efficacies of various antibiotic regimens administered as treatment for a mixed infection caused by Bacteroides fragilis and Escherichia coli in the irradiated...
Brook, Itzhak, Ledney, G. David
The effect of antimicrobial therapy on gut flora, sepsis, and mortality was investigated in C3H/HeN female mice irradiated with 7.0, 8.0 or 8.5 Gy or 60Co. The antimicrobial agents tested were...
The comparative efficacies of cefoxitin, cefotetan and the combination of ampicillin with sulbactam were investigated in mixed aerobic and anaerobic infections of mice. Treatment was administered by...
Brook, Itzhak, Gillmore, James D.
Cefoxitin, cefotetan, cefmetazole, ceftizoxime, imipenem plus cilastatin, ampicillin plus sulbactam and clindamycin alone or combined with gentamicin, ciprofloxacin, ofloxacin or aztreonam were...
Brook, Itzhak, Tom, Samuel P., Ledney, G. David
The use of ofloxacin and glycopeptides was evaluated for the treatment of infections arising in C3H/HeN female mice irradiated with 8.3 Gy from a 60Co source. The 21 day regimen began 72 h after...
A recent increase in numbers of β-lactamase-producing strains of aerobic and anaerobic Gram-negative bacteria in upper respiratory tract infections has been associated with increased failure rates...
The failure of penicillin to eradicate Group A β-haemorytic streptococcal tonsillitis may be caused by β-lactamase producing bacteria in the tonsillar tissue. A prospective randomized clinical...
The activity of metronidazole and spiramycin, singly or in combination, was tested in vitro and also in vivo, in the eradication of infection caused by Bacteroides spp. and Staphylococcus aureus,...
Brook, Itzhak, Walker, Richard I.
Seven anaerobic and facultative Gram-positive coca and 12 clostridial species were tested for in-vitro and in-vivo susceptibilities to penicillin, clindamycin, and metronidazole, used singly or in...
Brook, Itzhak, Pazzaglia, Gary, Coolbaugh, James C., Walker, Richard I.
The incidence of persistent group A β-haemolytic streptococci in tonsils, despite penicillin therapy, has increased in recent years. β-Lactamase-producing organisms have previously been recovered...
Aerobic and Anaerobic Microbiology of Surgical-Site Infection Following Spinal Fusion
Brook, Itzhak, Frazier, Edith H.
The aerobic and anaerobic microbiology of surgical-site infections (SSI) following spinal fusion was retrospectively studied. This was done by reviewing the clinical and microbiological records at...
In Vitro Development of Resistance to Ofloxacin and Doxycycline in Bacillus anthracis Sterne
Choe, Chong H., Bouhaouala, Selim S., Brook, Itzhak, Elliott, Thomas B., Knudson, Gregory B.
Elliott, Thomas B., Brook, Itzhak, Harding, Rita A., Bouhaouala, S. Samy, Shoemaker, Michael O., Knudson, Gregory B.
Challenge with both nonlethal ionizing radiation and toxigenic Bacillus anthracis spores increases the rate of mortality from a mixed bacterial infection. If biological weapons, such as B. anthracis...
Clinical review: Bacteremia caused by anaerobic bacteria in children
This review describes the microbiology, diagnosis and management of bacteremia caused by anaerobic bacteria in children. Bacteroides fragilis, Peptostreptococcus sp., Clostridium sp., and...
Unexplained fever in young children: how to manage severe bacterial infection
Fever with no clear source of infection in children under 3 years old carries a small but important risk of sepsis and meningitis. This review describes the bacterial causes of such infection and the...
Clindamycin in Treatment of Aspiration Pneumonia in Children
Twenty-eight patients with anaerobic pleuropulmonary infections were treated with clindamycin alone or clindamycin with gentamicin. Sixteen of the patients presented with pneumonitis, nine with...
Nasopharyngeal cultures were obtained from 60 children with acute otitis media before and after treatment with either 45 or 90 mg of amoxicillin (given as amoxicillin-clavulanate) per kg of body...
Bacteriology of Acute and Chronic Ethmoid Sinusitis
Aspirates from 26 acutely and 17 chronically infected ethmoid sinuses were studied. Thirty-seven aerobes and 10 anaerobes were recovered from isolates from patients with acute sinusitis....
Efficacy of Penicillin versus Cefdinir in Eradication of Group A Streptococci and Tonsillar Flora
Brook, Itzhak, Foote, Perry A.
Core tonsillar cultures were obtained from 40 children with recurrent tonsillitis treated with either penicillin or cefdinir. Group A beta-hemolytic streptococci were isolated from 11 penicillin- and...
Brook, Itzhak, Hausfeld, Jeffrey N.
The effect on the nasopharyngeal flora of 7 days of amoxicillin-clavulanate or 5 days of 800 mg once a day was studied in 50 adults with acute sinusitis. The numbers of potential pathogens and...
This study reports bacterial specimens obtained from 112 children presenting with a ruptured appendix. Additional samples were studied from 11 of these patients who developed a postoperative surgical...
Aerobic and Anaerobic Microbiology of Surgical-Site Infection Following Spinal Fusion
Brook, Itzhak, Frazier, Edith H.
The aerobic and anaerobic microbiology of surgical-site infections (SSI) following spinal fusion was retrospectively studied. This was done by reviewing the clinical and microbiological records at...
In Vitro Development of Resistance to Ofloxacin and Doxycycline in Bacillus anthracis Sterne
Choe, Chong H., Bouhaouala, Selim S., Brook, Itzhak, Elliott, Thomas B., Knudson, Gregory B.
Elliott, Thomas B., Brook, Itzhak, Harding, Rita A., Bouhaouala, S. Samy, Shoemaker, Michael O., Knudson, Gregory B.
Challenge with both nonlethal ionizing radiation and toxigenic Bacillus anthracis spores increases the rate of mortality from a mixed bacterial infection. If biological weapons, such as B. anthracis...
Clinical review: Bacteremia caused by anaerobic bacteria in children
This review describes the microbiology, diagnosis and management of bacteremia caused by anaerobic bacteria in children. Bacteroides fragilis, Peptostreptococcus sp., Clostridium sp., and...
Unexplained fever in young children: how to manage severe bacterial infection
Fever with no clear source of infection in children under 3 years old carries a small but important risk of sepsis and meningitis. This review describes the bacterial causes of such infection and the...
Clindamycin in Treatment of Aspiration Pneumonia in Children
Twenty-eight patients with anaerobic pleuropulmonary infections were treated with clindamycin alone or clindamycin with gentamicin. Sixteen of the patients presented with pneumonitis, nine with...
Nasopharyngeal cultures were obtained from 60 children with acute otitis media before and after treatment with either 45 or 90 mg of amoxicillin (given as amoxicillin-clavulanate) per kg of body...
Bacteriology of Acute and Chronic Ethmoid Sinusitis
Aspirates from 26 acutely and 17 chronically infected ethmoid sinuses were studied. Thirty-seven aerobes and 10 anaerobes were recovered from isolates from patients with acute sinusitis....
Efficacy of Penicillin versus Cefdinir in Eradication of Group A Streptococci and Tonsillar Flora
Brook, Itzhak, Foote, Perry A.
Core tonsillar cultures were obtained from 40 children with recurrent tonsillitis treated with either penicillin or cefdinir. Group A beta-hemolytic streptococci were isolated from 11 penicillin- and...
Brook, Itzhak, Hausfeld, Jeffrey N.
The effect on the nasopharyngeal flora of 7 days of amoxicillin-clavulanate or 5 days of 800 mg once a day was studied in 50 adults with acute sinusitis. The numbers of potential pathogens and...
This study reports bacterial specimens obtained from 112 children presenting with a ruptured appendix. Additional samples were studied from 11 of these patients who developed a postoperative surgical...
Carnaud, Claude, Ilfeld, David, Brook, Itzhak, Trainin, Nathan
Unprimed mouse spleen cells cultured in vitro on syngeneic tumor cell monolayers have been previously shown to become specifically sensitized and to mediate cytotoxicity against the same type of...