Jörg Bernhardt

Norvaline is accumulated after a down-shift of oxygen in Escherichia coli W3110 (2008)

Soini, Jaakko, Falschlehner, Christina, Liedert, Christina, Bernhardt, Jörg, Vuoristo, Jussi, Neubauer, Peter

Abstract Background Norvaline is an unusual non-proteinogenic branched-chain amino acid which has been of interest especially during the early enzymological studies on regulatory mutants of the...

Visual Analysis of Gel-free Proteome Data (2008)

Lars Linsen, Julia Löcherbach, Matthias Berth, Dörte Becher, Jörg Bernhardt

Abstract — We present a visual exploration system supporting protein analysis when using gel-free data acquisition methods. The data to be analyzed is obtained by coupling liquid chromatography...

Defining the proteome (2005)

Bernhardt, Jörg

A report on the Fourth Annual HUPO World Congress (HUPO2005) 'From Defining the Proteome to Understanding Function', Munich, Germany, 28 August-1 September 2005.

Differential protein expression analysis via liquid-chromatography/massspectrometry data visualization (2005)

Lars Linsen, Julia Löcherbach, Matthias Berth, Jörg Bernhardt, Dörte Becher

region of interest. Differential protein expression analysis is one of the main challenges in proteomics. It denotes the search for proteins, whose encoding genes are differentially expressed under a...

Bacillus subtilis During Feast and Famine: Visualization of the Overall Regulation of Protein Synthesis During Glucose Starvation by Proteome Analysis (2003)

Bernhardt, Jörg, Weibezahn, Jimena, Scharf, Christian, Hecker, Michael

Dual channel imaging and warping of two-dimensional (2D) protein gels were used to visualize global changes of the gene expression patterns in growing Bacillus subtilis cells during entry into the...

Identification of ςB-Dependent Genes in Bacillus subtilis Using a Promoter Consensus-Directed Search and Oligonucleotide Hybridization

Petersohn, Anja, Bernhardt, Jörg, Gerth, Ulf, Höper, Dirk, Koburger, Torsten, Völker, Uwe, ...

A consensus-directed search for ςB promoters was used to locate potential candidates for new ςB-dependent genes in Bacillus subtilis. Screening of those candidates by oligonucleotide hybridizations...

Role of CcpA in Regulation of the Central Pathways of Carbon Catabolism in Bacillus subtilis

Tobisch, Steffen, Zühlke, Daniela, Bernhardt, Jörg, Stülke, Jörg, Hecker, Michael

The Bacillus subtilis two-dimensional (2D) protein index contains almost all glycolytic and tricarboxylic acid (TCA) cycle enzymes, among them the most abundant housekeeping proteins of growing...

Bacillus subtilis During Feast and Famine: Visualization of the Overall Regulation of Protein Synthesis During Glucose Starvation by Proteome Analysis

Bernhardt, Jörg, Weibezahn, Jimena, Scharf, Christian, Hecker, Michael

Dual channel imaging and warping of two-dimensional (2D) protein gels were used to visualize global changes of the gene expression patterns in growing Bacillus subtilis cells during entry into the...

Defining the proteome

Bernhardt, Jörg

A report on the Fourth Annual HUPO World Congress (HUPO2005) ‘From Defining the Proteome to Understanding Function’, Munich, Germany, 28 August-1 September 2005.

Identification of ςB-Dependent Genes in Bacillus subtilis Using a Promoter Consensus-Directed Search and Oligonucleotide Hybridization

Petersohn, Anja, Bernhardt, Jörg, Gerth, Ulf, Höper, Dirk, Koburger, Torsten, Völker, Uwe, ...

A consensus-directed search for ςB promoters was used to locate potential candidates for new ςB-dependent genes in Bacillus subtilis. Screening of those candidates by oligonucleotide hybridizations...

Role of CcpA in Regulation of the Central Pathways of Carbon Catabolism in Bacillus subtilis

Tobisch, Steffen, Zühlke, Daniela, Bernhardt, Jörg, Stülke, Jörg, Hecker, Michael

The Bacillus subtilis two-dimensional (2D) protein index contains almost all glycolytic and tricarboxylic acid (TCA) cycle enzymes, among them the most abundant housekeeping proteins of growing...

Bacillus subtilis During Feast and Famine: Visualization of the Overall Regulation of Protein Synthesis During Glucose Starvation by Proteome Analysis

Bernhardt, Jörg, Weibezahn, Jimena, Scharf, Christian, Hecker, Michael

Dual channel imaging and warping of two-dimensional (2D) protein gels were used to visualize global changes of the gene expression patterns in growing Bacillus subtilis cells during entry into the...

Defining the proteome

Bernhardt, Jörg

A report on the Fourth Annual HUPO World Congress (HUPO2005) ‘From Defining the Proteome to Understanding Function’, Munich, Germany, 28 August-1 September 2005.

The state of the art in the analysis of two-dimensional gel electrophoresis images

Berth, Matthias, Moser, Frank Michael, Kolbe, Markus, Bernhardt, Jörg

Software-based image analysis is a crucial step in the biological interpretation of two-dimensional gel electrophoresis experiments. Recent significant advances in image processing methods combined...