J. A. Welsh

Publication List Details

Period

1981 - 1981

Number

9

Co-Authors

Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1.

Gerwin, B I, Spillare, E, Forrester, K, Lehman, T A, Kispert, J, Welsh, J A, ...

Loss of normal functions and gain of oncogenic functions when the p53 tumor suppressor gene is mutated are considered critical events in the development of the majority of human cancers. Human...

Frequent mutation of the p53 gene in human esophageal cancer.

Hollstein, M C, Metcalf, R A, Welsh, J A, Montesano, R, Harris, C C

Sequence alterations in the p53 gene have been detected in human tumors of the brain, breast, lung, and colon, and it has been proposed that p53 mutations spanning a major portion of the coding...

Mechanism of pyrimethamine resistance in recent isolates of Plasmodium falciparum.

McCutchan, T F, Welsh, J A, Dame, J B, Quakyi, I A, Graves, P M, Drake, J C, ...

Clones of Plasmodium falciparum prepared from recent isolates of infected blood were studied to determine the molecular mechanism of naturally occurring pyrimethamine resistance. Total DNA, as well...

In vivo testing of subunit vaccines against malaria sporozoites using a rodent system.

Lal, A A, De La Cruz, V F, Good, M F, Weiss, W R, Lunde, M, Maloy, W L, ...

To test the putative in vivo protective effects of antibodies to circumsporozoite (CS) protein repeats against malarial infection, different strains of mice were immunized against various repetitive...

Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1.

Gerwin, B I, Spillare, E, Forrester, K, Lehman, T A, Kispert, J, Welsh, J A, ...

Loss of normal functions and gain of oncogenic functions when the p53 tumor suppressor gene is mutated are considered critical events in the development of the majority of human cancers. Human...

Frequent mutation of the p53 gene in human esophageal cancer.

Hollstein, M C, Metcalf, R A, Welsh, J A, Montesano, R, Harris, C C

Sequence alterations in the p53 gene have been detected in human tumors of the brain, breast, lung, and colon, and it has been proposed that p53 mutations spanning a major portion of the coding...

Mechanism of pyrimethamine resistance in recent isolates of Plasmodium falciparum.

McCutchan, T F, Welsh, J A, Dame, J B, Quakyi, I A, Graves, P M, Drake, J C, ...

Clones of Plasmodium falciparum prepared from recent isolates of infected blood were studied to determine the molecular mechanism of naturally occurring pyrimethamine resistance. Total DNA, as well...

In vivo testing of subunit vaccines against malaria sporozoites using a rodent system.

Lal, A A, De La Cruz, V F, Good, M F, Weiss, W R, Lunde, M, Maloy, W L, ...

To test the putative in vivo protective effects of antibodies to circumsporozoite (CS) protein repeats against malarial infection, different strains of mice were immunized against various repetitive...