J. Andrew Williams

DNA damage in human breast milk cells and its induction by ‘early’ and ‘late’ milk extracts (2000)

L.Martin, Francis, J.Cole, Kathleen, Harvey, David, Weaver, Gillian, Williams, J.Andrew, C.Millar, Barbara, ...

Environmental and dietary factors are thought to be significant in breast cancer aetiology. The alkaline single-cell gel electrophoresis (‘Comet’) assay was used to examine breast milk cells for...

Pathways of heterocyclic amine activation in the breast: DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) formed by peroxidases and in human mammary epithelial cells and fibroblasts (2000)

Williams, J.Andrew, Stone, Elaine M., Millar, Barbara C., Hewer, Alan, Phillips, David H.

Most human mammary carcinomas originate in the epithelial cells of the breast ducts. A potential role of heterocyclic amines (HAs) in the aetiology of this disease has led us to investigate...

Induction of cytochrome P4503A in vivo and in vitro. (1995)

Williams, J. Andrew.

Thesis (Ph. D.)--University of Aberdeen, 1995.

Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation

Uchaipichat, Verawan, Winner, Leanne K, Mackenzie, Peter I, Elliot, David J, Williams, J Andrew, Miners, John O

Limited influence of UGT1A1*28 and no effect of UGT2B7*2 polymorphisms on UGT1A1 or UGT2B7 activities and protein expression in human liver microsomes

Peterkin, Vincent C, Bauman, Jonathan N, Goosen, Theunis C, Menning, Lee, Man, Michael Z, Paulauskis, Joseph D, ...

What is already known about this subjectThe UGT1A1*28 polymorphism is known to reduce UGT1A1 enzyme activities, via an extra TA repeat in the promoter.However, a gap exists with regard to a...