Mohrenweiser, H. W., Asakawa, J.
Two new electrophoretic variants of human triosephosphate isomerase (TPI) have been partially purified and characterized. The TPI Manchester variant, a cathodally migrating electrophoretic allozyme...
Thoraval, D, Asakawa, J, Kodaira, M, Chang, C, Radany, E, Kuick, R, ...
We have implemented an approach for the detection of DNA alterations in cancer by means of computerized analysis of end-labeled genomic fragments, separated in two dimensions. Analysis of...
Genetic variation detected by quantitative analysis of end-labeled genomic DNA fragments.
Asakawa, J, Kuick, R, Neel, J V, Kodaira, M, Satoh, C, Hanash, S M
The continuing efforts to evaluate specific human populations for altered germinal mutation rates would profit from more efficient and more specific approaches than those of the past. To this end, we...
Asakawa, J, Satoh, C, Yamasaki, Y, Chen, S H
We have developed a technique to detect accurately heterozygous carriers of a deletion. Specific target sequences were amplified by the polymerase chain reaction (PCR), and the products subsequently...
The rate with which spontaneous mutation alters the electrophoretic mobility of polypeptides.
Neel, J V, Satoh, C, Goriki, K, Fujita, M, Takahashi, N, Asakawa, J, ...
Studies of a Japanese population, involving a total of 539,170 locus tests distributed over 36 polypeptides, yielded three presumptive spontaneous mutations altering the electrophoretic mobility of...
Neel, J V, Satoh, C, Hamilton, H B, Otake, M, Goriki, K, Kageoka, T, ...
A total of 289,868 locus tests, based on 28 different protein phenotypes and using one-dimensional electrophoresis to detect variant proteins, has yielded one probable mutation in the offspring of...
Tsiagbe, V K, Yoshimoto, T, Asakawa, J, Cho, S Y, Meruelo, D, Thorbecke, G J
The MHC class II I-A(s) positive B cell lymphomas reticulum cell sarcoma (RCS) that arise in > 90% of SJL mice by the age of 12 months have superantigen-like stimulating properties. In the present...
Genetic analysis of children of atomic bomb survivors.
Satoh, C, Takahashi, N, Asakawa, J, Kodaira, M, Kuick, R, Hanash, S M, ...
Studies are under way for the detection of potential genetic effects of atomic bomb radiation at the DNA level in the children of survivors. In a pilot study, we have examined six minisatellites and...
Satoh, C, Takahashi, N, Asakawa, J, Hiyama, K, Kodaira, M
In the course of feasibility studies to examine the efficiencies and practicalities of various techniques for screening for genetic variations, the human coagulation factor IX (F9) genes of 63...
Thoraval, D, Asakawa, J, Kodaira, M, Chang, C, Radany, E, Kuick, R, ...
We have implemented an approach for the detection of DNA alterations in cancer by means of computerized analysis of end-labeled genomic fragments, separated in two dimensions. Analysis of...
Genetic variation detected by quantitative analysis of end-labeled genomic DNA fragments.
Asakawa, J, Kuick, R, Neel, J V, Kodaira, M, Satoh, C, Hanash, S M
The continuing efforts to evaluate specific human populations for altered germinal mutation rates would profit from more efficient and more specific approaches than those of the past. To this end, we...
Asakawa, J, Satoh, C, Yamasaki, Y, Chen, S H
We have developed a technique to detect accurately heterozygous carriers of a deletion. Specific target sequences were amplified by the polymerase chain reaction (PCR), and the products subsequently...
The rate with which spontaneous mutation alters the electrophoretic mobility of polypeptides.
Neel, J V, Satoh, C, Goriki, K, Fujita, M, Takahashi, N, Asakawa, J, ...
Studies of a Japanese population, involving a total of 539,170 locus tests distributed over 36 polypeptides, yielded three presumptive spontaneous mutations altering the electrophoretic mobility of...
Neel, J V, Satoh, C, Hamilton, H B, Otake, M, Goriki, K, Kageoka, T, ...
A total of 289,868 locus tests, based on 28 different protein phenotypes and using one-dimensional electrophoresis to detect variant proteins, has yielded one probable mutation in the offspring of...
Tsiagbe, V K, Yoshimoto, T, Asakawa, J, Cho, S Y, Meruelo, D, Thorbecke, G J
The MHC class II I-A(s) positive B cell lymphomas reticulum cell sarcoma (RCS) that arise in > 90% of SJL mice by the age of 12 months have superantigen-like stimulating properties. In the present...
Genetic analysis of children of atomic bomb survivors.
Satoh, C, Takahashi, N, Asakawa, J, Kodaira, M, Kuick, R, Hanash, S M, ...
Studies are under way for the detection of potential genetic effects of atomic bomb radiation at the DNA level in the children of survivors. In a pilot study, we have examined six minisatellites and...
Satoh, C, Takahashi, N, Asakawa, J, Hiyama, K, Kodaira, M
In the course of feasibility studies to examine the efficiencies and practicalities of various techniques for screening for genetic variations, the human coagulation factor IX (F9) genes of 63...
Neel, J V, Satoh, C, Goriki, K, Asakawa, J, Fujita, M, Takahashi, N, ...
A sample of (1) children whose parents had been proximally exposed (i.e., less than 2,000 m from the hypocenter) at the time of the atomic bombings of Hiroshima and Nagasaki and (2) a suitable...
Protein variants in Hiroshima and Nagasaki: tales of two cities.
Neel, J V, Satoh, C, Smouse, P, Asakawa, J, Takahashi, N, Goriki, K, ...
The results of 1,465,423 allele product determinations based on blood samples from Hiroshima and Nagasaki, involving 30 different proteins representing 32 different gene products, are analyzed in a...