J. Aten

Increased expression of heparanase in overt diabetic nephropathy (2006)

Rops, A.L., Bakker, M.A. Den, Aten, J., Rutjes, N., Roestenberg, P., ...

In overt diabetic nephropathy (DNP), an increase in the permeability of the glomerular basement membrane (GBM) has been associated with a loss of negatively charged heparan sulfates (HS) in the GBM....

Angiotensin converting enzyme inhibition prevents development of collapsing focal segmental glomerulosclerosis in Thy-1.1 transgenic mice (2006)

Smeets, B., Steenbergen, M.L.M., Verrijp, K.N., Aten, J., ...

Background. Thy-1.1 transgenic mice develop hypercellular focal and segmental glomerulosclerosis (FSGS) lesions that mimic human collapsing FSGS, in 7 days after injection with anti-Thy-1.1...

Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice (2006)

Roestenberg, P., Nieuwenhoven, F.A. Van, Joles, J.A., Trischberger, C., Martens, P.P., Oliver, N., ...

Connective tissue growth factor (CTGF) is overexpressed in diabetic nephropathy (DN) and has therefore been implicated in its pathogenesis. The objective of the present study was to determine the...

Human renal epithelial cells produce the long pentraxin PTX3 (2005)

Nauta, A.J., Haij, S. De, Bottazzi, B., Mantovani, A., Borrias, M.C., Aten, J., ...

Plasma chitotriosidase and CCL18: early biochemical surrogate markers in type B Niemann-Pick disease (2005)

Brinkman, J., Wijburg, F.A., Hollak, C.E.M., Groener, J.E.M., Verhoek, M., Scheij, S., ...

Effects of inhibition of the polyol pathway during chronic peritoneal exposure to a dialysis solution (2005)

Westrhenen, R. Van, Aten, J., Aberra, M., Dragt, C.A.M., Deira, G., Krediet, R.T.

Plasma chitotriosidase and CCL18: early biochemical surrogate markers in type B Niemann-Pick disease (2005)

Brinkman, J., Wijburg, F.A., Hollak, C.E.M., Groener, J.E.M., Verhoek, M., Scheij, S., ...

Effects of inhibition of the polyol pathway during chronic peritoneal exposure to a dialysis solution (2005)

Westrhenen, R. Van, Aten, J., Aberra, M., Dragt, C.A.M., Deira, G., Krediet, R.T.

Extra-dornain-a fibronectin: A new marker of fibrosis in cutaneous Graft-Versus-Host disease (2004)

Verdonck, L.F., Castigliego, D., Borst, H.P.E., Aten, J., ...

CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy (2004)

Rouschop, K.A.M., Sewnath, M.E., Claessen, N., Hoedemaeker, I., Neut, R. Van Der, ...

In situ expression of connective tissue growth factor in human crescentic glomerulonephritis (2004)

Kanemoto, K., Usui, J., Nitta, K., Horita, S., Harada, A., Koyama, A., ...

Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection (2003)

Rowshani, A.T., Claessen, N., Aten, J., ...

Increased expression of connective tissue growth factor in amyotrophic lateral sclerosis human spinal cord (2003)

Spliet, W.G.M., Aronica, E.M.A., Ramkema, M.D., Aten, J., Troost, D.

Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection (2003)

Rowshani, A.T., Claessen, N., Aten, J., ...

Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype (2003)

Smit, L.A., Bende, R.J., Aten, J., Guikema, J.E.J., Aarts, W.M.

Connective tissue growth factor participates in scar formation of crescentic glomerulonephritis (2003)

Kanemoto, K., Usui, J., Tomari, S., Yokoi, H., Mukoyama, M., Aten, J., ...

Increased expression of connective tissue growth factor in amyotrophic lateral sclerosis human spinal cord (2003)

Spliet, W.G.M., Aronica, E.M.A., Ramkema, M.D., Aten, J., Troost, D.

Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection (2003)

Rowshani, A.T., Claessen, N., Aten, J., ...

Increased expression of connective tissue growth factor in amyotrophic lateral sclerosis human spinal cord (2003)

Spliet, W.G.M., Aronica, E.M.A., Ramkema, M.D., Aten, J., Troost, D.

IgG subclass distribution of autoantibodies differs between renal and extra-renal relapses in patients with systemic lupus erythematosus (2002)

Bijl, M., Dijstelbloem, H., Oost, W.W., Bootsma, H., Aten, J., ...

Interleukin-4 and 13-promote basolateral secretion of H+ and cathepsin L by glomerular epithelial cells (2002)

Aten, J., Annink, C., Ravesloot, J-H., Weber, E., Weening, J.J.

Interleukin-4 and 13-promote basolateral secretion of H+ and cathepsin L by glomerular epithelial cells (2002)

Aten, J., Annink, C., Ravesloot, J-H., Weber, E., Weening, J.J.

Interleukin-4 and 13-promote basolateral secretion of H+ and cathepsin L by glomerular epithelial cells (2002)

Aten, J., Annink, C., Ravesloot, J-H., Weber, E., Weening, J.J.

Genotype versus phenotype: conflicting results in mapping a lung tumor susceptibility locus to the G7c recombination interval in the mouse MHC class III region (2001)

Kooij, M. Van, Groot, K. De, Vugt, H. Van, Aten, J., Snoek, M.

The immune dysregulatory compound mercuric chloride induces integrin-mediated T-lymphocyte adhesion (2001)

Roos, A., Neeft, M., Engelen, L., Kunzendorf, U., Weening, J.J., ...

Kinetics of connective tissue growth factor expression during experimental proliferative glomerulonephritis (2001)

Ito, Y., Goldschmeding, R., Bende, R.J., Claessen, N., Chand, M.A., Kleij, L., ...

Immunoglobulin V-H-gene usage of autoantibodies in mercuric chloride-induced membranous glomerulopathy in the rat (2001)

Dammers, P.M., Bellon, B., Kroese, F.G.M., Aten, J.

Severe non-proliferative lupus nephritis with predominant sub-endothelial IgA deposits (2001)

Florquin, S., Roos, A., Groothoff, J.W., Claessen, N., Aten, J., ...

In vitro evidence for differential involvement of CTGF, TGF beta, and PDGF-BB in mesangial response to injury (2001)

Blom, I.E., Dijk, A.J. Van, Wieten, L., Duran, K., Ito, Y., Kleij, L., ...

Expression and modulation of apoptosis regulatory molecules in human melanocytes: significance in vitiligo (2000)

Aten, J., Scheepmaker, A., Poole, I.C. Le, Tigges, A.J., Westerhof, W., ...

Strong and selective glomerular localization of CD134 ligand and TNF receptor-1 in proliferative lupus nephritis (2000)

Aten, J., Roos, A., Claessen, N., Weening, J.J.

Correction of liver disease by hepatocyte transplantationin a mouse model of progresssive familial intrahepatic cholectasis (2000)

Ottenhoff, R., Bosma, P.J., Smith, A.J., Aten, J.

Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis (2000)

Ottenhoff, R., Bosma, P.J., Smith, A.J., Aten, J.

Interleukin-4 and interleukin-13 act on glomerular visceral epithelial cells (2000)

Aten, J., Chand, M.A., Claessen, N., Dijkink, L., Wijdenes, J., ...

Strong and selective glomerular localization of CD134 ligand and TNF receptor-1 in proliferative lupus nephritis (2000)

Aten, J., Roos, A., Claessen, N., Weening, J.J.

Expression and modulation of apoptosis regulatory molecules in human melanocytes: significance in vitiligo (2000)

Aten, J., Scheepmaker, A., Poole, I.C. Le, Tigges, A.J., Westerhof, W., ...

Connective tissue growth factor: just another factor in renal fibrosis ? (2000)

Goldschmeding, R., Aten, J., Ito, Y., Blom, I., Rabelink, T., Weening, J.J.

Expression and modulation of apoptosis regulatory molecules in human melanocytes: significance in vitiligo (2000)

Aten, J., Scheepmaker, A., Poole, I.C. Le, Tigges, A.J., Westerhof, W., ...

Strong and selective glomerular localization of CD134 ligand and TNF receptor-1 in proliferative lupus nephritis (2000)

Aten, J., Roos, A., Claessen, N., Weening, J.J.

T cell/melanocyt interacties in vitiligo (1999)

Wankowicz-Kalinska, A., Poole, I.C. Le, Aten, J., Westerhof, W., Das, P.K.

Apoptotic tubular cell death during acute renal allograft rejection (1998)

Wever, P.C., Aten, J., Rentenaar, R.J., Hack, C.E., Koopman, G., Weening, J.J., ...

Apoptotic tubular cell death during acute renal allograft rejection (1998)

Wever, P.C., Aten, J., Rentenaar, R.J., Hack, C.E., Koopman, G., Weening, J.J., ...

Strong expression of CD134 (OX40), a member of the TNF receptor family, in a T helper 2-type cytokine environment (1998)

Roos, J., Schilder, E.J.M., Weening, J.J., Aten, J.

Differential expression of T-cell adhesion molecules and LFA-1-dependent intercellular adhesion in HgC12-induced autoimmunity and immune suppression (1998)

Roos, J., Claessen, N., Schilder, E.J.M., Weening, J.J., Aten, J.

Expression of connective tissue growth factor in human renal fibrosis (1998)

Ito, Y., Aten, J., Bende, R.J., Oemar, B.S., Rabelink, T.J., Weening, J.J., ...

Apoptotic tubular cell death during acute renal allograft rejection (1998)

Wever, P.C., Aten, J., Rentenaar, R.J., Hack, C.E., Koopman, G., Weening, J.J., ...

Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis (1998)

Jaquemin, E., Sturm, E., Cresteil, D., Bosma, P.J., Aten, J., ...

Class III type P-glycoproteins and their role in cholestatic liver disease (1998)

Sturm, E., Bosma, P.J., Aten, J., Burdelski, M., ...

Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis (1998)

Jacquemin, E., Sturm, E., Cresteil, D., Bosma, P.J., Aten, J., ...

HgCl2 and IL4 differentially modify expression of major histocompatibility complex class II molecules RT1.B and RT1.D in N lymphocytes from brown Norway and Lewis rats (1997)

Roos, J., Schilder, E.J.M., Chand, M.A., Weening, J.J., Aten, J.

Thiol levels in CD134-defined subsets of rat T lymphocytes: possible implications for HgCl2-induced immune dysregulation (1997)

Roos, J., Claessen, N., Schilder, E.J.M., Chand, M.A., Weening, J.J., Aten, J.

Glomerulopathy induced by graft-versus-host reaction in the rat. Requirement of donor CD4+ T lymphocytes and MHC class II incompatibility at the lymphoid compartment. (1992)

Aten, J., Stet, R.J.M., Weening, J.J., Fleueren, G.J., Nieuwenhuis, P.

The effect of aniosmotic media on the volume of the T-lymphocyte nucleus (1991)

Hoekstra, A.G., Aten, J., Sloot, P.M.A.

Time-resolved measurements of the nuclear volume response of human peripheral T-lymphocytes, under aniosmotic conditions, are presented. In the experiments slit scanning FlowCytometry methods were...

Pure chromosome-specific PCR libraries from single sorted chromosomes.

VanDevanter, D R, Choongkittaworn, N M, Dyer, K A, Aten, J, Otto, P, Behler, C, ...

Chromosome-specific DNA libraries can be very useful in molecular and cytogenetic genome mapping studies. We have developed a rapid and simple method for the generation of chromosome-specific DNA...

Pure chromosome-specific PCR libraries from single sorted chromosomes.

VanDevanter, D R, Choongkittaworn, N M, Dyer, K A, Aten, J, Otto, P, Behler, C, ...

Chromosome-specific DNA libraries can be very useful in molecular and cytogenetic genome mapping studies. We have developed a rapid and simple method for the generation of chromosome-specific DNA...

Differential regulation of expression of the MHC class II molecules RT1.B and RT1.D on rat B lymphocytes: effects of interleukin-4, interleukin-13 and interferon-gamma.

Roos, A, Schilder-Tol, E J, Chand, M A, Claessen, N, Lakkis, F G, Pascual, D W, ...

Susceptibility to induction of both T helper 1- (Th1) and Th2-mediated autoimmunity is multifactorial and involves genetic linkage to the major histocompatibility complex (MHC) class II haplotype....

The immune dysregulatory compound mercuric chloride induces integrin-mediated T-lymphocyte adhesion

Roos, A, Neeft, M, Engelen, L, Kunzendorf, U, Weening, J J, ...

Exposure of Brown Norway rats to mercuric chloride induces systemic autoimmunity, involving T- and B-lymphocyte activation, (auto-)antibody production and multiorgan inflammation. Several divalent...

Autoantibodies to the laminin P1 fragment in HgCl2-induced membranous glomerulopathy.

Aten, J., Veninga, A., Coers, W., Sonnenberg, A., Timpl, R., Claessen, N., ...

Exposure to mercuric chloride induces the development of a membranous glomerulopathy with high proteinuria in DZB rats, in which immunoglobulin (Ig)G1 and IgG2a bound in the glomeruli were previously...

Mercuric chloride-induced autoimmunity in the brown Norway rat. Cellular kinetics and major histocompatibility complex antigen expression.

Aten, J., Bosman, C. B., Rozing, J., Stijnen, T., Hoedemaeker, P. J., Weening, J. J.

HgCl2 induces an autoimmune syndrome in Brown Norway rats that involves synthesis of anti-glomerular basement membrane (GBM) antibodies and development of nephritis with high proteinuria....

Cyclosporin A induces long-term unresponsiveness in mercuric chloride-induced autoimmune glomerulonephritis.

Aten, J, Bosman, C B, De Heer, E, Hoedemaeker, P J, Weening, J J

Mercuric chloride induces a transient systemic T-lymphocyte dependent autoimmune syndrome in Brown Norway rats. Two weeks after the first HgCl2 injection maximum serum levels of anti-GBM antibodies...