Wiser, L C, Plain, R H, Dossetor, J B
It is possible for a nonpharmaceutical medical innovation to enter the mainstream of the health care system without its efficacy and effectiveness having first been established by means of a...
Morgan, K, Holmes, T M, Pazderka, F, Dossetor, J B
Segregation of HLA haplotypes and offspring genotype distributions were analyzed in families from an inbred Caucasoid population, the Dariusleut Hutterite Brethren. Both parents and from one to 12...
Morgan, K, Holmes, T M, Schlaut, J, Marchuk, L, Kovithavongs, T, Pazderka, F, ...
There are three endogamous subdivisions of the Hutterite population, a North American religious isolate. These individuals live on communal farms, and residence is strictly patrilocal. We report on...
Wiser, L C, Plain, R H, Dossetor, J B
It is possible for a nonpharmaceutical medical innovation to enter the mainstream of the health care system without its efficacy and effectiveness having first been established by means of a...
Morgan, K, Holmes, T M, Pazderka, F, Dossetor, J B
Segregation of HLA haplotypes and offspring genotype distributions were analyzed in families from an inbred Caucasoid population, the Dariusleut Hutterite Brethren. Both parents and from one to 12...
Morgan, K, Holmes, T M, Schlaut, J, Marchuk, L, Kovithavongs, T, Pazderka, F, ...
There are three endogamous subdivisions of the Hutterite population, a North American religious isolate. These individuals live on communal farms, and residence is strictly patrilocal. We report on...
Cutting the costs of dialysis by using paid helpers.
Higgins, M R, Bettcher, K B, Dossetor, J B, Rice, R, Mandin, H, LeTourneau, P
Fibroblast lysis by lymphocytes from normal persons and SLE patients on short-term cultures.
Liburd, E M, Pazderka, V, Russell, A S, Dossetor, J B
Lymphocytes from thirty-six normal individuals of both sexes with ages ranging from 4-89 years were tested for their cytotoxic activity against short term cluters of fibroblasts from nine foetal...
Latent carcinoma of the prostate in a 24-year-old man receiving cyclophosphamide and azathioprine.
Elliott, G. B., Silverberg, D. S., Dossetor, J. B., Muir, C. S.
Survival of patients treated for end-stage renal disease by dialysis and transplantation.
Higgins, M. R., Grace, M., Dossetor, J. B.
The results of treatment in 213 patients with end-stage renal disease who underwent hemodialysis, peritoneal dialysis or transplantation, or a combination, between 1962 and 1975 were analysed....
Radioconglutinin-binding azssay for circulating immune complexes: a new method.
Johny, K V, Dasgupta, M K, Singh, B, Dossetor, J B
A new method for the detection of circulating immune complexes using radiolabelled conglutinin as a marker for complement-bound complexes precipitated in low concentrations (3.5%) of polyethylene...
Cell-mediated autoimmunity in NZB mice
Stiller, C. R., Russell, A. S., McConnachie, P., Dossetor, J. B., Diener, E.
NZB mice spontaneously develop immune-complex nephritis comparable to that of human systemic lupus erythematosus in which the principal immunologic mechanism is thought to be humoral. A prominent...
An antibody to isogeneic fibroblasts in the serum of diseased NZB mice
Liburd, E., Russell, A. S., Dossetor, J. B.
We have described a new autoantibody present in the serum of diseased NZB mice reactive with autochthonous and syngeneic fibroblasts. Allogeneic cells are not affected. This antibody can be...
Taguchi, Y., MacKinnon, K. J., Helle, S., Dossetor, J. B.
Usefulness of intestinal perfusion in the treatment of uremia is limited by (a) low clearances, (b) atrophy of the perfused mucous membrane, and (c) poor toleration by the patient. A method of...
Cadaver Renal Homotransplants: Initial Experiences
Dossetor, J. B., Gault, M. H., Oliver, J. A., Inglis, F. G., MacKinnon, K. J., MacLean, L. D.
Four renal homotransplants were carried out between cadaver donors and four recipients, all of whom were in terminal chronic renal failure. Immune suppression was attempted with azathioprine...
Histoplasmosis and Thrombocytopenic Purpura: Transmission by Renal Homotransplantation
Hood, A. B., Inglis, F. G., Lowenstein, L., Dossetor, J. B., MacLean, L. D.
Two patients with disseminated histoplasmosis are reported. One patient presented with severe thrombocytopenic purpura and splenomegaly. Histoplasmin skin test, blood and bone marrow cultures and...
The 131I Ortho-iodohippurate Photoscan in Human Renal Allografts
Dossetor, J. B., Zweig, S. M., Treves, S., Ross, W. M.
Nine examples, in seven patients, from a large cadaver renal allograft program, illustrate the value of radio-hippuran photoscans in differentiating causes of post-implant oliguria. Hippuran scans...
Bone marrow transplantation in a patient with drug-induced aplastic anemia
Banerjee, T. K., Band, P. R., Pabst, H., Goldsand, G., Armstrong, W. D., Brown, J., ...
A 23-year-old woman gravely ill with Pseudomonas septicemia secondary to presumed drug-induced bone marrow aplasia received marrow transplantation from two male HL-A identical sibling donors. She had...
Differential Renal Function Studies in the Diagnosis of Renal Hypertension
Dossetor, J.B., Fam, W., Gutelius, J.R., Turgeon-Knaack, C., Morehouse, D. D.
Over a 10-year period, positive criteria of the Howard test and the Rapoport Index have shown consistently good correlation with sustained relief or marked improvement in hypertension, in patients...
Male Fertility in Uremia: Restoration by Renal Allografts
Phadke, A.G., MacKinnon, K.J., Dossetor, J.B.
Spermatogenesis has been studied in eight chronic uremic patients on hemodialysis and in 11 recipients of well-functioning renal allografts. Sexual activity, semen analysis and testicular biopsy are...
Silverberg, D. S., Dossetor, J. B., Eid, T. C., Mant, M. J., Miller, J. D. R.
A patient with membranoproliferative glomerulonephritis and mild hypertension is described who, after a renal biopsy, developed an arteriovenous fistula and then severe continuous hematuria from the...
Effect of I,25-dihydroxycholecalciferol in renal osteodystrophy.
Silverberg, D. S., Bettcher, K. B., Dossetor, J. B., Overton, T. R., Holick, M. F., DeLuca, H. F.
A 23-year-old man with medullary cystic disease had been undergoing hemodialysis for 5 years and had become confined to a wheelchair because of renal osteodystrophy. He was treated with...
Hydatidiform mole metastasizing to the lung.
Band, P. R., Masse, S. R., Reid, D. W., Dossetor, J. B.
Pulmonary lesions developed in three patients with an invasive hydatidiform mole. At open thoracotomy the modules were found to contain molar tissue. Therapy with twice-weekly methotrexate induced...