The Micro Slit Gas Detector (1998)
Labbé, J C, Gómez, F, Núñez, T
We describe the first tests with a new proportional gas detector. Its geometry consists in slits opened in a copper metallized kapton foil with 30 $\mu$m anode strips suspended in these openings. In...
Beam tests of the gas electron multiplier (1998)
Bressan, A, Labbé, J C, Pagano, P, Ropelewski, Leszek, Sauli, Fabio
We describe the results of systematic measurements, carried out with single and double GEM detectors with printed circuit read-out and having an active area 10x10 cm , both in the laboratory and in a...
Two-dimensional readout of GEM detectors (1998)
Bressan, A, De Oliveira, R, Gandi, A, Labbé, J C, Ropelewski, Leszek, Sauli, Fabio, ...
The recently introduced Gas Electron Multiplier (GEM) permits the amplification of electrons released by ionizing radiation in a gas by factors approaching ten thousand, larger gains can be obtained...
The Micro Slit Gas Detector (1998)
Labbé, J C, Gómez, F, Núñez, T
We describe the first tests with a new proportional gas detector. Its geometry consists in slits opened in a copper metallized kapton foil with 30 $\mu$m anode strips suspended in these openings. In...
Further developments of the gas electron multiplier (GEM) (1998)
Benlloch, J M, Bressan, A, Capéans-Garrido, M, Gruwé, M, Hoch, M, Labbé, J C, ...
We describe the development and operation of the Gas Electron Multiplier, a thin insulating foil metal-clad on both sides and perforated by a regular pattern of small holes. The mesh can be...
Development of the gas electron multiplier (GEM) (1998)
Benlloch, J M, Bressan, A, Büttner, C, Capéans-Garrido, M, Gruwé, M, Hoch, M, ...
We describe recent developments of the Gas Electron Multiplier (GEM), a thin composite mesh acting as proportional avalanche amplifier in gas counters. In beam tests we have verified the excellent...
Barr, A J, Bachmann, S, Boimska, B, Bouclier, Roger, Braem, André, Camps, C, ...
We describe the construction, test and installation procedures, and the experience gained with the operation of a small but complete system of high rate Micro-Strip Gas Chambers, made on thin...
Progress with the gas electron multiplier (1997)
Büttner, C, Capéans-Garrido, M, Dominik, Wojciech, Hoch, M, Labbé, J C, Manzin, G, ...
The Gas Electron Multiplier (GEM) amplifies electrons released in a gas and transfers them to a second element of detection, multi-wire or micro-strip chamber. We describe recent developments...
New observations with the gas electron multiplier (GEM) (1997)
Bouclier, Roger, Dominik, Wojciech, Hoch, M, Labbé, J C, Million, Gilbert, Ropelewski, Leszek, ...
We describe recent measurements realized with the Gas Electron Multiplier (GEM) mesh added as pre-amplification element to a multiwire and a micro-strip chamber. Large, stable combined gains are...
The gas electron multiplier (GEM) (1996)
Bouclier, Roger, Capéans-Garrido, M, Dominik, Wojciech, Hoch, M, Labbé, J C, Million, Gilbert, ...
We describe operating priciples and results obtained with a new detector component: the Gas Electrons Multiplier (GEM). Consisting of a thin composite sheet with two metal layers separated by a thin...
Mitosis-specific phosphorylation of nucleolin by p34cdc2 protein kinase.
Belenguer, P, Caizergues-Ferrer, M, Labbé, J C, Dorée, M, Amalric, F
Nucleolin is a ubiquitous multifunctional protein involved in preribosome assembly and associated with both nucleolar chromatin in interphase and nucleolar organizer regions on metaphasic chromosomes...
Devault, A, Martinez, A M, Fesquet, D, Labbé, J C, Morin, N, Tassan, J P, ...
The kinase responsible for Thr161-Thr160 phosphorylation and activation of cdc2/cdk2 (CAK:cdk-activating kinase) has been shown previously to comprise at least two subunits, cdk7 and cyclin H. An...
Labbé, J C, Martinez, A M, Fesquet, D, Capony, J P, Darbon, J M, Derancourt, J, ...
p40MO15, a cdc2-related protein, is the catalytic subunit of the kinase (CAK, cdk-activating kinase) responsible for Thr161/Thr160 phosphorylation and activation of cdk1/cdk2. We have found that...
Labbé, J C, Capony, J P, Caput, D, Cavadore, J C, Derancourt, J, Kaghad, M, ...
We have purified to near homogeneity the M-phase-specific protein kinase from starfish oocytes at first meiotic metaphase, using an improved procedure based on affinity chromatography on the...
Fesquet, D, Labbé, J C, Derancourt, J, Capony, J P, Galas, S, Girard, F, ...
Phosphorylation of Thr161, a residue conserved in all members of the cdc2 family, has been reported to be absolutely required for the catalytic activity of cdc2, the major regulator of eukaryotic...
Lorca, T, Labbé, J C, Devault, A, Fesquet, D, Capony, J P, Cavadore, J C, ...
Exit from metaphase of the cell cycle requires inactivation of MPF, a stoichiometric complex between the cdc2 catalytic and the cyclin B regulatory subunits, as well as that of cyclin A-cdc2 kinase....
Martinez, A M, Afshar, M, Martin, F, Cavadore, J C, Labbé, J C, Dorée, M
A cyclin-dependent kinase (cdk)-activating kinase (CAK) has been shown previously to catalyze T-loop phosphorylation of cdks in most eukaryotic cells. This enzyme exists in either of two forms: the...
Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts.
Lorca, T, Castro, A, Martinez, A M, Vigneron, S, Morin, N, Sigrist, S, ...
The Xenopus homologue of Drosophila Fizzy and budding yeast CDC20 has been characterized. The encoded protein (X-FZY) is a component of a high molecular weight complex distinct from the...
CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans.
Felkai, S, Ewbank, J J, Lemieux, J, Labbé, J C, Brown, G G, Hekimi, S
Mutations in the clk-1 gene of the nematode Caenorhabditis elegans result in an average slowing of a variety of developmental and physiological processes, including the cell cycle, embryogenesis,...
Labbé, J C, Hekimi, S, Rokeach, L A
The Ro ribonucleoproteins (RoRNP) consist of at least one major protein of 60 kD, Ro60, and one small associated RNA, designated Y RNA. Although RoRNP have been found in all vertebrate species...
Mitosis-specific phosphorylation of nucleolin by p34cdc2 protein kinase.
Belenguer, P, Caizergues-Ferrer, M, Labbé, J C, Dorée, M, Amalric, F
Nucleolin is a ubiquitous multifunctional protein involved in preribosome assembly and associated with both nucleolar chromatin in interphase and nucleolar organizer regions on metaphasic chromosomes...
Devault, A, Martinez, A M, Fesquet, D, Labbé, J C, Morin, N, Tassan, J P, ...
The kinase responsible for Thr161-Thr160 phosphorylation and activation of cdc2/cdk2 (CAK:cdk-activating kinase) has been shown previously to comprise at least two subunits, cdk7 and cyclin H. An...
Labbé, J C, Martinez, A M, Fesquet, D, Capony, J P, Darbon, J M, Derancourt, J, ...
p40MO15, a cdc2-related protein, is the catalytic subunit of the kinase (CAK, cdk-activating kinase) responsible for Thr161/Thr160 phosphorylation and activation of cdk1/cdk2. We have found that...
Labbé, J C, Capony, J P, Caput, D, Cavadore, J C, Derancourt, J, Kaghad, M, ...
We have purified to near homogeneity the M-phase-specific protein kinase from starfish oocytes at first meiotic metaphase, using an improved procedure based on affinity chromatography on the...
Fesquet, D, Labbé, J C, Derancourt, J, Capony, J P, Galas, S, Girard, F, ...
Phosphorylation of Thr161, a residue conserved in all members of the cdc2 family, has been reported to be absolutely required for the catalytic activity of cdc2, the major regulator of eukaryotic...
Lorca, T, Labbé, J C, Devault, A, Fesquet, D, Capony, J P, Cavadore, J C, ...
Exit from metaphase of the cell cycle requires inactivation of MPF, a stoichiometric complex between the cdc2 catalytic and the cyclin B regulatory subunits, as well as that of cyclin A-cdc2 kinase....
Martinez, A M, Afshar, M, Martin, F, Cavadore, J C, Labbé, J C, Dorée, M
A cyclin-dependent kinase (cdk)-activating kinase (CAK) has been shown previously to catalyze T-loop phosphorylation of cdks in most eukaryotic cells. This enzyme exists in either of two forms: the...
Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts.
Lorca, T, Castro, A, Martinez, A M, Vigneron, S, Morin, N, Sigrist, S, ...
The Xenopus homologue of Drosophila Fizzy and budding yeast CDC20 has been characterized. The encoded protein (X-FZY) is a component of a high molecular weight complex distinct from the...
CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans.
Felkai, S, Ewbank, J J, Lemieux, J, Labbé, J C, Brown, G G, Hekimi, S
Mutations in the clk-1 gene of the nematode Caenorhabditis elegans result in an average slowing of a variety of developmental and physiological processes, including the cell cycle, embryogenesis,...
Labbé, J C, Hekimi, S, Rokeach, L A
The Ro ribonucleoproteins (RoRNP) consist of at least one major protein of 60 kD, Ro60, and one small associated RNA, designated Y RNA. Although RoRNP have been found in all vertebrate species...