Integrated microsystem for non-invasive electrophysiological measurements on Xenopus oocytes (2007)
Dahan, Elodie, Bize, V., Lehnert, T., Horisberger, J. D., Gijs, M.A.M.
On-chip non-invasive voltage clamp on Xenopus oocytes (2005)
Dahan, E., Bize, V., Lehnert, T., Horisberger, J.D., Gijs, M.A.M.
In order to improve the throughput of the traditional “Two Electrode Voltage Clamp” (TEVC) measurements on Xenopus oocytes, we present here a chip-based non-invasive technique for the measurement...
Modular microsystem for epithelial cell culture and electrical characterisation (2001)
Hediger, S., Sayah, A., Horisberger, J.D., Gijs, M. A. M.
We have realised a microsystem for the culture and electrical characterisation of epithelial cell layers for cell-based diagnostic applications. The main goal of this work is to achieve both cell...
A mouse model for Liddle's syndrome (1999)
Pradervand, S., Wang, Q., Burnier, M., Beermann, F., Horisberger, J. D., Hummler, E., ...
A mouse model for the renal salt-wasting syndrome pseudohypoaldosteronism (1997)
Hummler, E., Barker, P., Talbot, C., Wang, Q., Verdumo, C., Grubb, B., ...
Aldosterone-dependent epithelial sodium transport in the distal nephron is mediated by the absorption of sodium through the highly selective, amiloride-sensitive epithelial sodium channel (ENaC) made...
Horisberger, J D, Jaunin, P, Good, P J, Rossier, B C, Geering, K
The active Na+/K+ pump is composed of an alpha and a beta subunit. Until now, three putative isoforms of the beta subunit have been identified that share sequence similarity. We have expressed the...
Canessa, C M, Horisberger, J D, Louvard, D, Rossier, B C
The cardiac glycoside ouabain inhibits Na,K-ATPase by binding to the alpha subunit. In a highly ouabain resistant clone from the MDCK cell line, we have found two alleles of the alpha subunit in...
The gamma subunit is a specific component of the Na,K-ATPase and modulates its transport function.
Béguin, P, Wang, X, Firsov, D, Puoti, A, Claeys, D, Horisberger, J D, ...
The role of small, hydrophobic peptides that are associated with ion pumps or channels is still poorly understood. By using the Xenopus oocyte as an expression system, we have characterized the...
Role in cation translocation of the N-terminus of the alpha-subunit of the Na(+)-K+ pump of Bufo.
Wang, X, Jaisser, F, Horisberger, J D
1. We have studied the effects on the physiological properties of the Na(+)-K+ pump of both 31- and 40-amino acid N-terminal truncated forms of the alpha-subunit of the Na(+)-K(+)-ATPase. 2. Na(+)-K+...
Horisberger, J D, Jaunin, P, Good, P J, Rossier, B C, Geering, K
The active Na+/K+ pump is composed of an alpha and a beta subunit. Until now, three putative isoforms of the beta subunit have been identified that share sequence similarity. We have expressed the...
Canessa, C M, Horisberger, J D, Louvard, D, Rossier, B C
The cardiac glycoside ouabain inhibits Na,K-ATPase by binding to the alpha subunit. In a highly ouabain resistant clone from the MDCK cell line, we have found two alleles of the alpha subunit in...
Role in cation translocation of the N-terminus of the alpha-subunit of the Na(+)-K+ pump of Bufo.
Wang, X, Jaisser, F, Horisberger, J D
1. We have studied the effects on the physiological properties of the Na(+)-K+ pump of both 31- and 40-amino acid N-terminal truncated forms of the alpha-subunit of the Na(+)-K(+)-ATPase. 2. Na(+)-K+...
The gamma subunit is a specific component of the Na,K-ATPase and modulates its transport function.
Béguin, P, Wang, X, Firsov, D, Puoti, A, Claeys, D, Horisberger, J D, ...
The role of small, hydrophobic peptides that are associated with ion pumps or channels is still poorly understood. By using the Xenopus oocyte as an expression system, we have characterized the...