J. D. Speelman

Determinants of disability and quality of life in mild to moderate Parkinson disease (2008)

Muslimovic, D., Post, B., Speelman, J.D., Schmand, B., Haan, R.J. De

Objective: To identify factors that independently contribute to disability and quality of life (QoL) in patients with mild to moderate Parkinson disease (PD). Methods: A group of 190 patients with PD...

Motor procedural learning in Parkinson's disease (2007)

Muslimovic, D., Post, B., Speelman, J. D., Schmand, B.

Functional neuroimaging research has repeatedly implicated the striatum in motor procedural learning, but attempts to explore this relation in patients with Parkinson's disease (PD) have yielded...

The AMC Linear Disability Score in patients with newly diagnosed Parkinson disease (2007)

Weisscher, N., Post, B., Haan De, R.J., Glas, C.A.W., Speelman, J.D., Vermeulen, N.D.

Objective: The aim of this study was to examine the clinimetric properties of the AMC Linear Disability Score (ALDS), a new generic disability measure based on Item Response Theory, in patients with...

New actigraph for long-term tremor recording (2006)

Pticek, M.D., Speelman, J.D., Schuurman, P.R., Esselink, R., Swaab, D.F.

A new method of movement analysis is validated, allowing an actigraph to discriminate tremor from other movements and store duration and intensity measures of both movement types. For algorithm...

Stimulation of the subthalamic region facilitates the selection and inhibition of motor responses in Parkinson's disease (2006)

Bosch, D.A., Speelman, J.D., Brunia, C.H.M.

The aim of the present study was to specify the involvement of the basal ganglia in motor response selection and response inhibition, Two samples Were studied. The First sample consisted of patients...

Neuropsychological effects of bilateral STN stimulation in Parkinson disease - A controlled study (2006)

Smeding, H.M.M., Speelman, J.D., Koning-Haanstra, M., Schuurman, P.R., Nijssen, P., Laar, T. Van Der, ...

Objective: To evaluate the cognitive and behavioral effects of bilateral subthalamic nucleus (STN) stimulation in patients with Parkinson disease (PD). Methods: The authors included 103 patients; 99...

Phenotype-genotype correlation in Dutch patients with myoclonus-dystonia (2006)

Gerrits, M.C.F., Foncke, E.M.J., Haan, R. De, Hedrich, K., Ozelius, L.J., ...

The epsilon-sarcoglycan (SGCE) gene is an important cause of myoclonus-dystonia (M-D), although the majority of cases with an M-D phenotype test negative. Seven of 31 patients with the M-D phenotype...

Unilateral pallidotomy versus bilateral subthalamic nucleus stimulation in Parkinson's disease: one year follow-up of a randomised observer-blind multi centre trial (2006)

Esselink, R.A.J., Haan, R.J. De, Beute, G.N., Portman, A.T., ...

Background. To investigate whether STN stimulation is more efficacious than unilateral pallidotomy in advanced Parkinson's disease (PD) one year after surgery. Method. Thirty-four patients with...

Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up (2005)

Rodriguez-Oroz, M. C., Obeso, J. A., Lang, A. E., Pollak, P., Rehncrona, S., ...

Deep brain stimulation (DBS) is associated with significant improvement of motor complications in patients with severe Parkinson's disease after some 6–12 months of treatment. Long-term results in...

Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up (2005)

Rodriguez-Oroz, M. C., Obeso, J. A., Lang, A. E., Pollak, P., Rehncrona, S., ...

Deep brain stimulation (DBS) is associated with significant improvement of motor complications in patients with severe Parkinson's disease after some 6-12 months of treatment. Long-term results in a...

Blepharospasm In Association With A Lower Pontine Lesion. (1996)

Aramideh, M., Ongerboer De Visser, B.W., Holstege, G., Majoie, G., Speelman, J.D.

A patient with neurofibromatosis type I and breast carcinoma developed a bilateral but asymmetric blepharospasm and paresis of the left abducens muscle over a 2-week course. MRI disclosed a small...

Abnormal eye movements in blepharospasm and involuntary levator palpebrae inhibition: Clinical and pathophysiological considerations (1994)

Aramideh, M., Bour, L. J., Speelman, J. D., Ongerboer De Visser, B. W.

We report on four patients with involuntary eyelid closure and eye movement disorders. Three were healthy until the onset of their illness and one had a mild generalized choreoathetosis and dystonia...

Pretarsal application of botulinum toxin for treatment of blepharospasm.

Aramideh, M, Ongerboer De Visser, B W, Brans, J W, Koelman, J H, Speelman, J D

The response to botulinum toxin type A was compared after two injection techniques in 45 patients with blepharospasm. Initially, patients were treated according to a triple injection technique; two...

Quality of life in patients with Parkinson's disease: development of a questionnaire.

De Boer, A G, Wijker, W, Speelman, J D, De Haes, J C

OBJECTIVES--To develop and test a questionnaire for measuring quality of life in patients with Parkinson's disease. METHODS--An item pool was developed based on the experience of patients with...

[123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson's disease.

Booij, J, Tissingh, G, Boer, G J, Speelman, J D, Stoof, J C, Janssen, A G, ...

OBJECTIVES: The main neuropathological feature in Parkinson's disease is a severe degeneration of the dopaminergic neurons in the substantia nigra resulting in a loss of dopamine (DA) transporters in...

Stereotactic thalamotomy for the relief of intention tremor of multiple sclerosis.

Speelman, J D, Van Manen, J

The results of a stereotactic thalamotomy in 11 patients with clinically definite multiple sclerosis and severe intention tremor are discussed. The operation produces a beneficial effect on the...

Acute dysautonomia associated with Hodgkin's disease.

Van Lieshout, J J, Wieling, W, Van Montfrans, G A, Settels, J J, Speelman, J D, Endert, E, ...

A patient is described with acute dysautonomia associated with Hodgkin's disease. Testing of cardiovascular reflex control showed that this patient had a rare manifestation of autonomic...

Electromyography and recovery of the blink reflex in involuntary eyelid closure: a comparative study.

Aramideh, M, Eekhof, J L, Bour, L J, Koelman, J H, Speelman, J D, Ongerboer De Visser, B W

Electromyographic (EMG) activity of orbicularis oculi and levator palpebrae muscles was recorded to study the origin of involuntary eyelid closure in 33 patients. The evoked blink reflex in all...