Telmisartan to prevent recurrent stroke and cardiovascular events (2008)
Yusuf, S, Diener, HC, Sacco, RL, Cotton, D, Ounpuu, S, Lawton, WA, ...
Background Prolonged lowering of blood pressure after a stroke reduces the risk of recurrent stroke. In addition, inhibition of the renin–angiotensin system in high-risk patients reduces the rate...
Telmisartan to prevent recurrent stroke and cardiovascular events (2008)
Yusuf, S, Diener, HC, Sacco, RL, Cotton, D, Ounpuu, S, Lawton, WA, ...
Background Prolonged lowering of blood pressure after a stroke reduces the risk of recurrent stroke. In addition, inhibition of the renin–angiotensin system in high-risk patients reduces the rate...
Utility of the stroke-thrombolytic predictive instrument (2008)
Uyttenboogaart, M., Stewart, R.E., Vroomen, P.C., Luijckx, G.J., De Keyser, J.
Objective: The goal of this study was to evaluate the utility of the stroke thrombolytic predictive instrument (s-TPI) in predicting clinical outcome in patients with acute ischaemic stroke treated...
Moderate hyperglycaemia is associated with favourable outcome in acute lacunar stroke (2007)
Uyttenboogaart, M., Koch, M.W., Stewart, R.E., Vroomen, P.C., Luijckx, G.J., De Keyser, J.
Hyperglycaemia in acute ischaemic stroke is traditionally associated with a worsened outcome. However, it is unclear whether the impact of hyperglycaemia on stroke outcome is similar in lacunar and...
Safety of routine IV thrombolysis between 3 and 4.5 h after ischemic stroke (2007)
Uyttenboogaart, M., Stewart, R.E., De Keyser, J., Luijckx, G.J.
Background: The administration of tissue plasminogen activator (t-PA) has been proven effective for ischemic stroke within 3 h after onset. A pooled-analysis of six trials showed that intravenous...
Moderate hyperglycaemia is associated with favourable outcome in acute lacunar stroke (2007)
Uyttenboogaart, M., Koch, M.W., Stewart, R.E., Vroomen, P.C., Luijckx, G.J., De Keyser, J.
Hyperglycaemia in acute ischaemic stroke is traditionally associated with a worsened outcome. However, it is unclear whether the impact of hyperglycaemia on stroke outcome is similar in lacunar and...
Safety of routine IV thrombolysis between 3 and 4.5 h after ischemic stroke (2007)
Uyttenboogaart, M., Stewart, R.E., De Keyser, J., Luijckx, G.J.
Background: The administration of tissue plasminogen activator (t-PA) has been proven effective for ischemic stroke within 3 h after onset. A pooled-analysis of six trials showed that intravenous...
Moderate hyperglycaemia is associated with favourable outcome in acute lacunar stroke (2007)
De Keyser, J., Luijckx, G.J., Vroomen, P.C., Stewart, R.E., Koch, M.W., Uyttenboogaart, M.
Hyperglycaemia in acute ischaemic stroke is traditionally associated with a worsened outcome. However, it is unclear whether the impact of hyperglycaemia on stroke outcome is similar in lacunar and...
Safety of routine IV thrombolysis between 3 and 4.5 h after ischemic stroke (2007)
Stewart, R.E., Uyttenboogaart, M., De Keyser, J., Luijckx, G.J.
Background: The administration of tissue plasminogen activator (t-PA) has been proven effective for ischemic stroke within 3 h after onset. A pooled-analysis of six trials showed that intravenous...
ROSINA - ROSETTA orbiter spectrometer for ion and neutral analysis (2007)
Balsiger, H., Altwegg, K., Bochsler, P., Eberhardt, P., Fischer, J., Graf, S., ...
Sheared magnetospheric plasma flows and discrete auroral arcs: a quasi-static coupling model (2007)
Echim, M. M., Roth, M., De Keyser, J.
We consider sheared flows in magnetospheric boundary layers of tangential discontinuity type, forming a structure that is embedded in a large-scale convergent perpendicular electric field. We...
Sheared magnetospheric plasma flows and discrete auroral arcs: a quasi-static coupling model (2007)
Echim, M. M., Roth, M., De Keyser, J.
We consider sheared flows in magnetospheric boundary layers of tangential discontinuity type, forming a structure that is embedded in a large-scale convergent perpendicular electric field. We...
De Keyser, J., Darrouzet, F., Dunlop, M. W., Décréau, P. M. E.
This paper describes a general-purpose algorithm for computing the gradients in space and time of a scalar field, a vector field, or a divergence-free vector field, from in situ measurements by one...
De Keyser, J., Darrouzet, F., Dunlop, M. W., Décréau, P. M. E.
This paper describes a general-purpose algorithm for computing the gradients in space and time of a scalar field, a vector field, or a divergence-free vector field, from in situ measurements by one...
Analysis of plasmaspheric plumes: CLUSTER and IMAGE observations (2006)
Darrouzet, F., De Keyser, J., Décréau, P. M. E., Gallagher, D. L., Pierrard, V., Lemaire, J. F., ...
Plasmaspheric plumes have been routinely observed by CLUSTER and IMAGE. The CLUSTER mission provides high time resolution four-point measurements of the plasmasphere near perigee. Total electron...
Analysis of plasmaspheric plumes: CLUSTER and IMAGE observations (2006)
Darrouzet, F., De Keyser, J., Décréau, P. M. E., Gallagher, D. L., Pierrard, V., Lemaire, J. F., ...
Plasmaspheric plumes have been routinely observed by CLUSTER and IMAGE. The CLUSTER mission provides high time resolution four-point measurements of the plasmasphere near perigee. Total electron...
Uyttenboogaart, M., Stewart, R.E., Vroomen, P.C., De Keyser, J., Luijckx, G.J.
BACKGROUND AND PURPOSE: There is little agreement on how to assess outcome in acute stroke trials. Cutoff scores for the Barthel Index (BI) and modified Rankin Scale (mRS) are frequently arbitrarily...
Bosma, R., Wynia, K., Havlikova, E., De Keyser, J., Middel, B.
OBJECTIVES: The current review evaluates the safety and efficacy of desmopressin in patients with multiple sclerosis (MS) who suffer from both daytime and nocturnal voiding frequency and from...
Uyttenboogaart, M., Stewart, R.E., Vroomen, P.C., De Keyser, J., Luijckx, G.J.
BACKGROUND AND PURPOSE: There is little agreement on how to assess outcome in acute stroke trials. Cutoff scores for the Barthel Index (BI) and modified Rankin Scale (mRS) are frequently arbitrarily...
Bosma, R., Wynia, K., Havlikova, E., De Keyser, J., Middel, B.
OBJECTIVES: The current review evaluates the safety and efficacy of desmopressin in patients with multiple sclerosis (MS) who suffer from both daytime and nocturnal voiding frequency and from...
Magnetopause and boundary layer (2005)
De Keyser, J., Dunlop, M. W., Owen, C. J., Sonnerup, B. U. Ö., Haaland, S. E., Vaivads, A., ...
De Keyser, J., Roth, M., Dunlop, M. W., Rème, H., Owen, C. J., Paschmann, G.
The magnetospheric boundary is always moving, making it difficult to establish its structure. This paper presents a novel method for tracking the motion of the boundary, based on in-situ observations...
De Keyser, J., Roth, M., Dunlop, M. W., Rème, H., Owen, C. J., Paschmann, G.
The magnetospheric boundary is always moving, making it difficult to establish its structure. This paper presents a novel method for tracking the motion of the boundary, based on in-situ observations...
Oeseburg, B., Jansen, D., De Keyser, J.
The Dutch healthcare system is effective for patients with acute, uncomplicated health problems but ineffective for patients with complex, chronic health problems such as multiple sclerosis (MS). To...
Oeseburg, B., Jansen, D., De Keyser, J.
The Dutch healthcare system is effective for patients with acute, uncomplicated health problems but ineffective for patients with complex, chronic health problems such as multiple sclerosis (MS). To...
Density structures inside the plasmasphere: Cluster observations (2004)
Darrouzet, F., Décréau, P. M. E., De Keyser, J., Masson, A., Gallagher, D. L., Santolik, O., ...
The electron density profiles derived from the EFW and WHISPER instruments on board the four Cluster spacecraft reveal density structures inside the plasmasphere and at its outer boundary, the...
De Keyser, J., Gustafsson, G., Roth, M., Darrouzet, F., Dunlop, M., Rème, H., ...
Multi-spacecraft data from Cluster allow for a more detailed magnetopause and boundary layer structure determination than ever before. Reconstruction methods, in which the time variability observed...
Density structures inside the plasmasphere: Cluster observations (2004)
Darrouzet, F., Décréau, P. M. E., De Keyser, J., Masson, A., Gallagher, D. L., Santolik, O., ...
The electron density profiles derived from the EFW and WHISPER instruments on board the four Cluster spacecraft reveal density structures inside the plasmasphere and at its outer boundary, the...
De Keyser, J., Gustafsson, G., Roth, M., Darrouzet, F., Dunlop, M., Rème, H., ...
Multi-spacecraft data from Cluster allow for a more detailed magnetopause and boundary layer structure determination than ever before. Reconstruction methods, in which the time variability observed...
Continuous pulse oximetry in acute hemiparetic stroke (2000)
Sulter, G., Elting, J.W., Stewart, R., Den Arend, A., De Keyser, J.
Background and purpose: Hypoxemia can adversely affect ischemic brain tissue in laboratory animals. The aim of this study was to assess the Value of early continuous monitoring with pulse oximetry in...
Continuous pulse oximetry in acute hemiparetic stroke (2000)
Sulter, G., Elting, J.W., Stewart, R., Den Arend, A., De Keyser, J.
Background and purpose: Hypoxemia can adversely affect ischemic brain tissue in laboratory animals. The aim of this study was to assess the Value of early continuous monitoring with pulse oximetry in...
Risks of multiple sclerosis in relatives of patients in Flanders, Belgium (1997)
Debruyne, J, De Keyser, J, D'Hooghe, M B, ...
OBJECTIVES: To calculate age adjusted risks for multiple sclerosis in relatives of Flemish patients with multiple sclerosis. METHODS: Lifetime risks were calculated using the maximum likelihood...
The European Stroke Scale (1994)
De Keyser, J, Diener, H C, Franke, C, Palm, R, ...
BACKGROUND AND PURPOSE: For detecting therapeutic effect and matching of treatment groups in stroke trials, a scale that meets the clinimetric criteria is of the utmost importance. METHODS: The...
Schoenen, Jean, Bulcke, J, Caekebeke, J, Dehaene, I, De Keyser, J, Hildebrand, G, ...
In a multicenter open longitudinal clinical trial where 479 patients suffering from migraine with or without aura were recruited, patients treated at home one to three migraine attacks with their...
Risks of multiple sclerosis in relatives of patients in Flanders, Belgium.
Carton, H, Vlietinck, R, Debruyne, J, De Keyser, J, D'Hooghe, M B, Loos, R, ...
OBJECTIVES: To calculate age adjusted risks for multiple sclerosis in relatives of Flemish patients with multiple sclerosis. METHODS: Lifetime risks were calculated using the maximum likelihood...
Low leucocyte myeloperoxidase activity in patients with multiple sclerosis
Ramsaransing, G, Teelken, A, Prokopenko, V, Arutjunyan, A., De Keyser, J
Mostert, J. P., Blaauw, Y., Koch, M. W., Kuiper, A. J., Hoogduin, J. M., De Keyser, J.
N-acetylaspartate/creatine (NAA/Cr) ratios, assessed with proton magnetic resonance spectroscopy, are increasingly used as a surrogate marker for axonal dysfunction and degeneration in multiple...
Aspirin and Extended-Release Dipyridamole versus Clopidogrel for Recurrent Stroke
Sacco, RL, Diener, Hans-Christoph, Yusuf, S, Cotton, D, Ounpuu, S, Lawton, WA, ...
Background Recurrent stroke is a frequent, disabling event after ischemic stroke. This study compared the efficacy and safety of two antiplatelet regimens — aspirin plus extendedrelease...
Enophthalmos as a rare manifestation of metastatic orbital involvement.
De Keyser, J., Bruyland, M., De Greve, J., Bernheim, J., Ebinger, G.
Two cases in which orbital metastasis produced enophthalmos, instead of the usual exophthalmos, are reported. Only fourteen other cases have been described previously and they are reviewed. At time...
Plasma homocysteine levels in multiple sclerosis
Ramsaransing, G S M, Fokkema, M R, Teelken, A, Arutjunyan, A V, Koch, M, De Keyser, J
Aspirin and Extended-Release Dipyridamole versus Clopidogrel for Recurrent Stroke
Sacco, RL, Diener, Hans-Christoph, Yusuf, S, Cotton, D, Ounpuu, S, Lawton, WA, ...
Background Recurrent stroke is a frequent, disabling event after ischemic stroke. This study compared the efficacy and safety of two antiplatelet regimens — aspirin plus extendedrelease...