Petri, M, Kasitanon, N, Lee, SS, Link, K, Magder, L, Bae, SC, ...
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Illei, G. G., Yarboro, C. H., Kuroiwa, T., Schlimgen, R., Austin, H. A., Tisdale, J. F., ...
Objectives. To determine the safety and efficacy of a short course of fludarabine combined with cyclophoshamide in lupus nephritis. Methods. A phase I/II open label pilot study. Thirteen patients...
Illei, G. G., Yarboro, C. H., Kuroiwa, T., Schlimgen, R., Austin, H. A., Tisdale, J. F., ...
Objectives. To determine the safety and efficacy of a short course of fludarabine combined with cyclophoshamide in lupus nephritis. Methods. A phase I/II open label pilot study. Thirteen patients...
Illei, G. G., Yarboro, C. H., Kuroiwa, T., Schlimgen, R., Austin, H. A., Tisdale, J. F., ...
Objectives. To determine the safety and efficacy of a short course of fludarabine combined with cyclophoshamide in lupus nephritis. Methods. A phase I/II open label pilot study. Thirteen patients...
The classification of glomerulonephritis in systemic lupus erythematosus revisited (2004)
Weening, J.J., D'Agati, V.D., Schwartz, M.M., Seshan, S.V., Alpers, C.E., Appel, G.B., ...
The classification of glomerulonephritis in systemic lupus erythematosus revisited (2004)
Weening, J.J., D'Agati, V.D., Schwartz, M.M., Seshan, S.V., Alpers, C.E., Appel, G.B., ...
Aksentijevich, I., Centola, M., Deng, Z. M., Sood, R., Balow, J. E., Wood, G., ...
Familial Mediterranean fever (FMF) is a recessively inherited disorder characterized by dramatic episodes of fever and serosal inflammation. This report describes the cloning of the gene likely to...
Austin, H. A., Boumpas, D. T., Vaughan, E. M., Balow, J. E.
Background The pleomorphic nature of lupus nephritis has confounded efforts to refine estimates of prognosis. Consideration of interactions among prognostic factors may help to identify high-risk...
Inghirami, G, Nakamura, M, Balow, J E, Notkins, A L, Casali, P
Epstein-Barr virus (EBV) was purified and biotinylated without significant loss of its cell-transforming activity. The use of biotinylated virus in conjunction with antibodies specific for selected...
Boumpas, D T, Anastassiou, E D, Older, S A, Tsokos, G C, Nelson, D L, Balow, J E
Glucocorticosteroids have an inhibitory effect on the expression of interleukin 2 (IL-2) and interleukin 2 receptor (IL-2R) genes. To determine the mechanisms of this inhibition, human T lymphocytes...
Balow, J E, Hurley, D L, Fauci, A S
The characteristics of cyclophosphamide-induced suppression of established ccll mediated immunity were studied in guinea pigs previously senstized to tuberculin. Cyclophosphamide treatment for 5 days...
Human bone marrow lymphocytes. Cytotoxic effector cells in the bone marrow of normal individuals.
Fauci, A S, Balow, J E, Pratt, K R
This study was undertaken to determine the capability of lymphocytes in the bone marrow of normal individuals to mediate nonspecific killer cell functions in assays of phytohemagglutinin...
Inghirami, G, Nakamura, M, Balow, J E, Notkins, A L, Casali, P
Epstein-Barr virus (EBV) was purified and biotinylated without significant loss of its cell-transforming activity. The use of biotinylated virus in conjunction with antibodies specific for selected...
Boumpas, D T, Anastassiou, E D, Older, S A, Tsokos, G C, Nelson, D L, Balow, J E
Glucocorticosteroids have an inhibitory effect on the expression of interleukin 2 (IL-2) and interleukin 2 receptor (IL-2R) genes. To determine the mechanisms of this inhibition, human T lymphocytes...
Balow, J E, Hurley, D L, Fauci, A S
The characteristics of cyclophosphamide-induced suppression of established ccll mediated immunity were studied in guinea pigs previously senstized to tuberculin. Cyclophosphamide treatment for 5 days...
Human bone marrow lymphocytes. Cytotoxic effector cells in the bone marrow of normal individuals.
Fauci, A S, Balow, J E, Pratt, K R
This study was undertaken to determine the capability of lymphocytes in the bone marrow of normal individuals to mediate nonspecific killer cell functions in assays of phytohemagglutinin...
Characterization of the direct effects of cyclophosphamide on cell-mediated immunological responses.
Balow, J E, Parrillo, J E, Fauci, A S
The direct immunosuppressive effects of cyclophosphamide were examined by incubating normal guinea-pig mononuclear cells with activated cyclophosphamide prepared from the serum of separate animals...
Regulation of immunoglobulin secretion by factor H of human complement.
Tsokos, G C, Inghirami, G, Tsoukas, C D, Balow, J E, Lambris, J D
As human B lymphocytes and macrophages carry surface receptors for Factor H (B1H), we investigated the possibility that this complement component regulates their function. Factor H inhibits...
Tsokos, G C, Christian, C B, Balow, J E
Experiments were performed to examine whether the concanavalin A (Con A)- induced suppressor cells of several in vitro T- and B-lymphocyte functions constitute a functionally unique cell population....
Bernstein, K A, Kahl, L E, Balow, J E, Lefkowith, J B
In order to assess the ability of various serologic assays to correlate with lupus nephritis, we analysed sera obtained from 60 patients with systemic lupus erythematosus (SLE). Patients were...
Miller, F W, Love, L A, Barbieri, S A, Balow, J E, Plotz, P H
We studied the immunologic correlates of disease activity and differences among subgroups of patients with idiopathic inflammatory myopathy by analysing phenotypic and activation marker expression on...
Tsokos, G C, Balow, J E, Huston, D P, Wei, N, Decker, J L
Nine patients with active systemic lupus erythematosus entered a double-blind randomized trial to study the therapeutic effect of vigorous versus sham reinfusion plasmapheresis. Four of them received...
Natural killer cells and interferon responses in patients with systemic lupus erythematosus.
Tsokos, G C, Rook, A H, Djeu, J Y, Balow, J E
Natural killer (NK) cell activity was studied in 23 patients with systemic lupus erythematosus (SLE). The overall NK activity was lower in patients with SLE than in normal female individuals....
Decreased interleukin 2 inhibitor in sera of patients with autoimmune disorders.
Djeu, J Y, Kasahara, T, Balow, J E, Tsokos, G C
The lymphokine, interleukin 2 (IL-2), is an important modulator of cell-mediated immune (CMI) responses. We report here the detection of an inhibitor of IL-2 in normal sera by measuring the...
Levy, E. N., Shen, Y., Kupelian, A., Kruglyak, L., Aksentijevich, I., Pras, E., ...
This report presents refined genetic mapping data for the gene causing familial Mediterranean fever (FMF), a recessively inherited disorder of inflammation. We sampled 65 Jewish, Armenian, and Arab...