J. G. Coote

Functional and structural studies on different forms of the adenylate cyclase toxin of Bordetella pertussis (2009)

Cheung, G.Y.C., Kelly, S.M., Jess, T.J., Prior, S., Price, N.C., Parton, R.G., ...

A comparison was made of the cytotoxic activity and secondary structural features of four recombinant forms of adenylate cyclase toxin (CyaA). These forms were fully functional CyaA, CyaA lacking...

Virulence spectra of typed strains of Campylobacter jejuni from different sources: a blinded in vivo study (2009)

Coote, J.G., Thompson, D.H., Candlish, D., Wardlaw, A.C., Candlish, A.

Campylobacter jejuni is a major cause of human diarrhoeal disease, but specific virulence mechanisms have not been well defined. The aims of the present blinded study were to measure and compare the...

Transcriptional responses of murine macrophages to the adenylate cyclase toxin of bordetella pertussis (2008)

Cheung, G.Y.C., Dickinson, P., Sing, G., Craigon, M., Ghazal, P., Parton, R., ...

Three different recombinant forms of CyaA were used to investigate transcriptional responses of murine bone marrow-derived macrophages (BMMs) using Affymetrix Mouse Genome GeneChips((R)). These forms...

Effect of different forms of adenylate cyclase toxin of Bordetella pertussis on protection afforded by an acellular pertussis vaccine in a murine model (2006)

Cheung, G.Y.C., Xing, D., Prior, S., Corbel, M.J., Parton, R., Coote, J.G.

Four recombinant forms of the cell-invasive adenylate cyclase toxin (CyaA) of Bordetella pertussis were compared for the ability to enhance protection against B. pertussis in mice when coadministered...