A cognitive approach to identifying measurable milestones for programming skill acquisition (2006)
Mead, J, Gray, S, Hamer, J, James, R, Sorva, J, St. Clair, C, ...
Traditional approaches to programming education, as exemplified by the typical CS1/CS2 course sequence, have not taken advantage of the long record of psychological and experimental studies on the...
Rahman, Z, Kavanagh, J, Champlin, R, Giles, R, Hanania, E, Fu, SQ, ...
Most patients relapse after high-dose chemotherapy (HDCT) with autologous stem-cell transplantation (ASCT) for metastatic breast cancer. Further chemotherapy immediately after hematopoietic recovery...
The Use of New Generation Stainless Steels in Combustion Systems. (1998)
Control of emission in fossil fuel fired power generation plants has brought about significant changes in combustion systems; these changes have increased the demands placed on alloys used in...
Johansson, R., Hamer, J., Redmond, J. D., Davison, R. M.
The combined effect of rare earth metals(REM), silicon and nitrogen on high temperature properties of austenitic stainless steels has been studied in three steels with increasing alloy content,...
Hanania, EG, Kavanagh, J, Giles, RE, Kudelka, A, Rahman, Z, Holmes, F, ...
Multi-Methods in a Statically-Typed Programming Language (1991)
Mugridge, R.B., Hamer, J., Hosking, J.G.
Multivariant functions in Kea are a statically-typed form of the multi-methods of CLOS (Keene, 1989) but encapsulation is retained. Multivariants permit fine typing distinctions to be made, allow...
THE EFFECT OF CARBON DIOXIDE ON CEREBRAL BLOOD FLOW AND CEREBRAL METABOLISM IN DOGS (1975)
ALBERTI, E., HAMER, J., STOECKEL, H., PACKSCHIESS, P., WEINHARDT, F.
In 11 normally oxygenated, normotensive mongrel dogs, blood flow and oxidative metabolism of the brain was studied during normocapnia and during respiratory alkalosis and respiratory acidosis....
The Effect of Noradrenaline on the Calcium Uptake of the Sarcoplasmic Reticulum (1969)
Shinebourne, E. A., Hess, M. L., White, R. J., Hamer, J.
Authors' SynopsisIt is known that noradrenaline has a profound effect on myocardial contractility, but no satisfactory explanation of this process at a cellular level has been available previously....
Knight, R K, Miall, P A, Hawkins, L A, Dacombe, J, Edwards, C R, Hamer, J
To assess the relation of hyperaldosteronism and potassium depletion to the intensity of diuretic therapy we have measured plasma aldosterone by radioimmunoassay and total exchangeable potassium by...
Stephens, J, Hayward, R, Ead, H, Adams, L, Hamer, J, Spurrell, R
The effects on coronary dynamics of propranolol and atenolol were studied in 12 patients undergoing cardiac catheterisation for suspected coronary artery disease. Myocardial blood flow was measured...
Potassium Depletion in Severe Heart Disease
White, R. J., Chamberlain, D. A., Hamer, J., McAlister, Joan, Hawkins, L. A.
Exchangeable sodium and potassium, total body water, and sulphate space were measured in 42 patients with severe valvular heart disease who were free of oedema. Compared with normal subjects of the...
Vasodilatation in the treatment of congestive heart failure
1 To reduce load on the failing heart would seem likely to improve its performance, but it is remarkable that apparently adverse effects such as reduced filling pressure and arterial vasodilatation...
Systemic availability of oral verapamil and effect on PR interval in man.
Johnston, A, Burgess, C D, Hamer, J
1 The plasma levels of verapamil and its major metabolite norverapamil were related to its effect as a Ca-antagonist on atrio-ventricular (AV) conduction, judged from prolongation of the PR interval...
Procainamide absorption studies to test the feasibility of using a sustained-release preparation.
Shaw, T R, Kumana, C R, Kaye, C M, Padgham, C, Kaspi, T, Hamer, J
Using in vitro techniques it was confirmed that whilst the release of procainamide from the conventional formulation (Pronestyl) was rapid, that from the sustained-release preparation (Cardiorytmin...
Relationship between myocardial uptake and actions in heart failure of methyldigoxin.
Hayward, R, Greenwood, H, Stephens, J, Hamer, J
1 Problems have been encountered in recent years in confirming useful benefit to patients with heart failure and sinus rhythm from acute exposure to digitalis glycosides, though effectiveness of...
Comparison of digoxin and medigoxin in normal subjects.
Hayward, R P, Greenwood, H, Hamer, J
1 The properties of a recently introduced digitalis glycoside, 4-beta-methyl digoxin (medigoxin) were compared to those of a standard digoxin preparation. Using a radioimmunoassay (RIA) technique,...
Hamer, J., Boulton, T., Fleming, J., Hayward, G. W., Hill, I. M., Monro, I., ...
The first 16 patients to have mitral valve replacement with the Starr-Edwards prosthesis at St. Bartholomew's Hospital, London, were reviewed from one to three years after operation. These patients...
Some cardiovascular problems with disopyramide.
Five patients with apparent adverse cardiovascular effects of disopyramide are reveiwed. Attention is drawn to the following problems. (1) A vagolytic effect may produce a sinus tachycardia with wide...