J. Hampe

Publication List Details

Period

1993 - 2008

Number

36

Co-Authors

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. (2008)

Tomlinson, I.P.M., Webb, E., Carvajal-Carmona, L., Broderick, P., Howarth, K., Pittman, A.M., ...

To identify colorectal cancer (CRC) susceptibility alleles, we conducted a genome-wide association study. In phase 1, we genotyped 550,163 tagSNPs in 940 familial colorectal tumor cases (627 CRC, 313...

The gene for autosomal dominant craniometaphyseal dysplasia maps to chromosome 5p and is distinct from the growth hormone-receptor gene.

Nürnberg, P, Tinschert, S, Mrug, M, Hampe, J, Müller, C R, Fuhrmann, E, ...

Craniometaphyseal dysplasia (CMD) is an osteochondrodysplasia of unknown etiology characterized by hyperostosis and sclerosis of the craniofacial bones associated with abnormal modeling of the...

A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort.

Hampe, J, Schreiber, S, Shaw, S H, Lau, K F, Bridger, S, Macpherson, A J, ...

Inflammatory bowel disease (IBD) is characterized by a chronic relapsing intestinal inflammation, typically starting in early adulthood. IBD is subdivided into two subtypes, on the basis of clinical...

A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort.

Hampe, J, Schreiber, S, Shaw, S H, Lau, K F, Bridger, S, Macpherson, A J, ...

Inflammatory bowel disease (IBD) is characterized by a chronic relapsing intestinal inflammation, typically starting in early adulthood. IBD is subdivided into two subtypes, on the basis of clinical...

The gene for autosomal dominant craniometaphyseal dysplasia maps to chromosome 5p and is distinct from the growth hormone-receptor gene.

Nürnberg, P, Tinschert, S, Mrug, M, Hampe, J, Müller, C R, Fuhrmann, E, ...

Craniometaphyseal dysplasia (CMD) is an osteochondrodysplasia of unknown etiology characterized by hyperostosis and sclerosis of the craniofacial bones associated with abnormal modeling of the...

Activation of nuclear factor κB in inflammatory bowel disease

Schreiber, S, Nikolaus, S, Hampe, J

Charité University Hospital, 4th Medical Department, Humboldt University, Berlin, Germany

Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease

Hampe, J, Lynch, N, Daniels, S, Bridger, S, Macpherson, A, Stokkers, P, ...

BACKGROUND AND AIMS—Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has...

Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease

Schreiber, S, Rosenstiel, P, Hampe, J, Nikolaus, S, Groessner, B, Schottelius, A, ...

Background: Increased expression of proinflammatory cytokines, including tumour necrosis factor α, interleukin 6, and interferon γ, as well as activation of proinflammatory signalling molecules...

Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease

Ott, S J, Musfeldt, M, Wenderoth, D F, Hampe, J, Brant, O, Fölsch, U R, ...

Background and aims: The intestinal bacterial microflora plays an important role in the aetiology of inflammatory bowel disease (IBD). As most of the colonic bacteria cannot be identified by culture...

Genetic variants in the CCR gene cluster and spontaneous viral elimination in hepatitis C-infected patients

MASCHERETTI, S, HINRICHSEN, H, ROSS, S, BUGGISCH, P, HAMPE, J, FOELSCH, U R, ...

Hepatitis C virus (HCV) infection results in chronic hepatitis in more than 80% of infected patients while 10–20% of patients recover spontaneously. Host genetic factors may influence the ability...

Activation of signal-transducer and activator of transcription 1 (STAT1) in pouchitis

Kühbacher, T, Gionchetti, P, Hampe, J, Helwig, U, Rosenstiel, P, Campieri, M, ...

Activation of signal transducer and activator of transcription 1 (STAT1) is a hallmark of IFN-γ receptor signal transduction but is also part of the signalling pathway of other cytokines/growth...

Study of Toll-like receptor gene loci in sarcoidosis

Schürmann, M, Kwiatkowski, R, Albrecht, M, Fischer, A, Hampe, J, Müller-Quernheim, J, ...

Sarcoidosis is a multi-factorial systemic disease of granulomatous inflammation. Current concepts of the aetiology include interactions of unknown environmental triggers with an inherited...